专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5921967A Plunger for nozzle assembly 失效
标题翻译：喷嘴组装用柱塞
公开(公告)号：US5921967A
公开(公告)日：1999-07-13
申请号：US773660
申请日：1996-12-24
申请人： Peter L. Sadowski , David Schiff , Walter Stoeckmann , Paul Mulhauser
发明人： Peter L. Sadowski , David Schiff , Walter Stoeckmann , Paul Mulhauser
IPC分类号： A61M5/30 , A61M5/315 , A61M5/50 , A61M5/00
CPC分类号： A61M5/5066 , A61M5/30 , A61M2005/31516 , A61M2005/5073 , A61M5/31515
摘要： The present invention is directed toward a plunger provided for use in a nozzle assembly. The nozzle assembly includes an internal chamber with an outwardly tapered portion at one end thereof. The plunger includes a plurality of outwardly curved prongs or legs which mate with an inwardly tapered portion of the internal chamber in order to allow the piston of the injector to be released from the plunger. As a result, the plunger may be removed from the injector when the nozzle assembly is removed therefrom. This plunger may include a frangible portion so that, upon firing, a first driving member of the plunger breaks away from a second driving member of the plunger. As a result of this frangible connection, the first driving member remains lodged in a distal portion of the chamber to prevent reuse of the nozzle assembly.
摘要翻译：本发明涉及一种用于喷嘴组件中的柱塞。喷嘴组件包括在其一端具有向外锥形部分的内部腔室。柱塞包括多个向外弯曲的插脚或支腿，其与内部腔室的向内的锥形部分配合，以便允许喷射器的活塞从柱塞释放。结果，当喷嘴组件从其中移除时，柱塞可以从喷射器移除。该柱塞可以包括易碎部分，使得在点火时，柱塞的第一驱动构件从柱塞的第二驱动构件脱离。作为这种易断连接的结果，第一驱动构件保持在腔室的远端部分中，以防止喷嘴组件重复使用。

2. 发明授权

US5769138A Nozzle and adapter for loading medicament into an injector 失效
标题翻译：用于将药剂装入注射器的喷嘴和适配器
公开(公告)号：US5769138A
公开(公告)日：1998-06-23
申请号：US625881
申请日：1996-04-01
申请人： Peter L. Sadowski , Sheldon Nelson , David Schiff , Walter Stoeckmann
发明人： Peter L. Sadowski , Sheldon Nelson , David Schiff , Walter Stoeckmann
IPC分类号： B65B1/04 , A61J1/00 , A61J1/20 , A61M5/30
CPC分类号： A61J1/2096 , A61M5/30 , A61J1/201 , A61J1/2055
摘要： An injector nozzle which has a body defining a chamber. A portion of the body has an orifice which communicates with the chamber for allowing fluid to enter into or exit from the chamber. The nozzle body includes at least one depression which is configured and dimensioned to cooperatively engage a tab member of an associated component for coupling thereto. The depression is also configured and dimensioned to positively lock the body to the associated component. The body portion which contains the depression is spaced proximally from the orifice. Also, an adapter for coupling the nozzle to a fluid container. The adapter includes a tubular member having first and second ends and a wall therebetween. The wall includes a passageway therethrough with the first end being dimensioned and configured to cooperatively engage the nozzle. The orifice of the nozzle generally aligns with the wall passageway for fluid communication therebetween. The second end of the adapter is configured and dimensioned to cooperatively engage a fluid container. These devices can be used in combination to provide a system for filling an injector with medicament.
摘要翻译：一种具有限定腔室的主体的喷射器喷嘴。身体的一部分具有与腔室连通的孔口，用于允许流体进入或离开腔室。喷嘴主体包括至少一个凹陷，其被构造和尺寸设计成与相关联的部件的凸片构件配合地接合以便与其连接。凹陷还被构造和尺寸确定以将身体正确地锁定到相关联的部件。包含凹陷的主体部分与孔口向近侧间隔开。另外，用于将喷嘴连接到流体容器的适配器。适配器包括具有第一端和第二端以及其间的壁的管状构件。该壁包括通过其中的通道，其第一端的尺寸和构造成与喷嘴配合地接合。喷嘴的孔口通常与壁通道对准以在其间流体连通。适配器的第二端被构造和尺寸设计成与流体容器配合地接合。这些装置可以组合使用以提供用于用药剂填充注射器的系统。

3. 发明授权

US5697917A Nozzle assembly with adjustable plunger travel gap 失效
标题翻译：喷嘴总成可调节柱塞行程间隙
公开(公告)号：US5697917A
公开(公告)日：1997-12-16
申请号：US609146
申请日：1996-02-29
申请人： Peter L. Sadowski , David Schiff , Paul Mulhauser
发明人： Peter L. Sadowski , David Schiff , Paul Mulhauser
IPC分类号： A61M5/30 , A61M5/50 , A61M5/00
CPC分类号： A61M5/30 , A61M5/5066 , A61M2005/5073
摘要： The present invention relates to a nozzle assembly adapted for use with an injector device having an energy generating source and a chamber adapted for holding a fluid and having first and second end portions with an orifice defined at the first end portion for passage of the fluid and being open at the second end portion. The device includes a first driving member movably positioned in the chamber; a second driving member movably positioned in the chamber and spaced apart from the first driving member according to a predetermined travel distance and including an end portion operative for expelling fluid out of or drawing fluid into the chamber via the orifice; and a spacing member disposed between the first and second driving members for maintaining said predetermined travel distance during displacement of the first and second driving members before the energy generating source is activated.
摘要翻译：本发明涉及一种喷嘴组件，其适于与具有能量产生源和适于保持流体的腔室一起使用的喷射器装置一起使用，并具有第一和第二端部，该第一和第二端部具有限定在第一端部处的流体通道，在第二端部开口。该装置包括可移动地定位在腔室中的第一驱动构件; 第二驱动构件，其可移动地定位在所述腔室中并且根据预定行进距离与所述第一驱动构件间隔开，并且包括端部，其用于将流体经由所述孔排出或将流体引入所述腔室; 以及设置在所述第一和第二驱动构件之间的间隔构件，用于在所述能量产生源被激活之前，在所述第一和第二驱动构件的位移期间保持所述预定行驶距离。

4. 发明授权

US08579865B2 Hazardous agent injection system 有权
公开(公告)号：US08579865B2
公开(公告)日：2013-11-12
申请号：US13257555
申请日：2010-03-19
申请人： Paul Wotton , Peter L. Sadowski , John William Hayes
发明人： Paul Wotton , Peter L. Sadowski , John William Hayes
IPC分类号： A61M5/00 , A61M5/315
CPC分类号： A61M5/30 , A61K9/0019 , A61K9/0087 , A61K31/519 , A61K31/568 , A61M5/178 , A61M5/2033 , A61M5/3202 , A61M5/326 , A61M2005/2013 , A61M2005/2073 , A61M2005/3247
摘要： Injection systems comprising a powered injector and one or more hazardous agents are disclosed.

5. 发明授权

US08419686B2 Intradermal injector 有权
标题翻译：皮内注射器
公开(公告)号：US08419686B2
公开(公告)日：2013-04-16
申请号：US13427969
申请日：2012-03-23
申请人： Peter L. Sadowski , Paul R. Lesch, Jr. , David L. Bremseth
发明人： Peter L. Sadowski , Paul R. Lesch, Jr. , David L. Bremseth
IPC分类号： A61M37/00
CPC分类号： A61M5/3204 , A61M5/2033 , A61M5/2046 , A61M5/2053 , A61M5/2459 , A61M5/3134 , A61M5/3202 , A61M5/326 , A61M5/425 , A61M2005/206 , A61M2005/2073 , A61M2005/3118
摘要： An injection device that comprises a chamber configured for containing a substance to be injected and a needle operatively associated with the chamber and having a length sufficient to deliver the substance to an intradermal injection site. A collar surrounds the needle, defining a collar cavity. The collar also has a peripheral forward skin-contacting surface that surrounds and is radially spaced from the needle and injection site by an area that is sufficiently large to allow a patient's skin to move into the collar cavity to properly position the needle for intradermal delivery of the substance to the injection site to allow spread of the injected substance under the skin while inhibiting or preventing backpressure within the skin from forcing the substance out through the injection site.
摘要翻译：一种注射装置，其包括被配置为容纳要注射的物质的腔室和与腔室可操作地相关联并且具有足以将物质输送到皮内注射部位的长度的针。衣领围绕针，限定一个衣领腔。套环还具有外围的向前皮肤接触表面，该表面围绕并且与针和注射部位径向间隔开足够大的区域，以允许患者的皮肤移动到套环空腔中以适当地定位针以便皮内递送该物质到注射部位以允许将注射物质扩散到皮肤下，同时抑制或防止皮肤内的背压，从而迫使物质通过注射部位。

6. 发明申请

US20130018313A1 INJECTION DEVICE WITH CAMMED RAM ASSEMBLY 有权
公开(公告)号：US20130018313A1
公开(公告)日：2013-01-17
申请号：US13184229
申请日：2011-07-15
申请人： Thomas Kramer , Matthew Howard Rust , Paul Michael Goudreau , Peter Anthony Hoeft , Julius Craig Sund , Peter L. Sadowski
发明人： Thomas Kramer , Matthew Howard Rust , Paul Michael Goudreau , Peter Anthony Hoeft , Julius Craig Sund , Peter L. Sadowski
IPC分类号： A61M5/20
CPC分类号： A61M5/5086 , A61M5/2033 , A61M5/30 , A61M5/3007 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/3247 , A61M2205/584
摘要： An exemplary embodiment of the present disclosure can provide an injector including a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

7. 发明授权

US06565553B2 Needle assisted jet injector 有权
标题翻译：针辅助喷射器
公开(公告)号：US06565553B2
公开(公告)日：2003-05-20
申请号：US10062652
申请日：2002-01-31
申请人： Peter L. Sadowski , David M. DeBoer , Claude L. Berman , Paul R. Lesch, Jr.
发明人： Peter L. Sadowski , David M. DeBoer , Claude L. Berman , Paul R. Lesch, Jr.
IPC分类号： A61M3100
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： The invention relates to methods and devices for delivering medicament by jet injection to an injection site in a patient. The method includes inserting a needle into an insertion point, wherein the needle has a length of less than 5 mm and is operatively associated with an orifice in a nozzle assembly in fluid communication with an ampule chamber containing the medicament. The needle extends less than about 5 mm from the nozzle assembly orifice when the medicament is expelled. Next, a force generating mechanism is activated, and a pressure wall member that is operatively associated with the force generating member moves in response to the activation of the force generating mechanism at a speed sufficient to jet inject the medicament from the ampule chamber through the orifice and needle under a pressure of less than about 4000 psi to deliver a substantial portion of the medicament through the needle and past the insertion point to the injection site. The needle tip maybe part of a retractable needle of a jet injection device, or is part of a fixed needle of a jet injection device.
摘要翻译：本发明涉及通过射流注射将药物输送到患者的注射部位的方法和装置。该方法包括将针插入插入点，其中针具有小于5mm的长度并且与喷嘴组件中的孔口可操作地相关联，该喷嘴组件与容纳药物的安瓿室流体连通。当药物被排出时，针从喷嘴组件孔口延伸小于约5mm。接下来，启动力产生机构，并且与力产生构件可操作地相关联的压力壁构件响应于力产生机构的激活而移动，其速度足以喷射从安瓿室喷射药物通过孔和针在小于约4000psi的压力下，以将大部分药物通过针输送并穿过插入点至注射部位。针尖可以是喷射装置的可缩回针的一部分，或者是喷射装置的固定针的一部分。

8. 发明申请

US20130030367A1 HAZARDOUS AGENT INJECTION SYSTEM 有权
标题翻译：危险代理注射系统
公开(公告)号：US20130030367A1
公开(公告)日：2013-01-31
申请号：US13607659
申请日：2012-09-07
申请人： Paul Wotton , Peter L. Sadowski , John William Hayes
发明人： Paul Wotton , Peter L. Sadowski , John William Hayes
IPC分类号： A61M5/20
CPC分类号： A61M5/30 , A61K9/0019 , A61K9/0087 , A61K31/519 , A61K31/568 , A61M5/178 , A61M5/2033 , A61M5/3202 , A61M5/326 , A61M2005/2013 , A61M2005/2073 , A61M2005/3247
摘要： A hazardous agent injection system including from about 0.02 ml to about 4.0 ml of methotrexate at a concentration of from about 7.5 mg/ml to about 150 mg/ml; a needle-assisted jet injector including a container configured to contain the methotrexate; a injection outlet member associated with the container; an injection-assisting needle coupled to the injection outlet member; a firing mechanism associated with the container; an energy source associated with the firing mechanism; and a trigger mechanism associated with the firing mechanism, wherein the needle-assisted jet injector is configured to eject the methotrexate from the injection outlet member such that the Cmax, Tmax and bioavailability of the needle-assisted jet injected methotrexate falls between about 80% and about 125% of the Cmax, Tmax and bioavailability of methotrexate delivered by a hand-powered syringe.
摘要翻译：一种危险剂注射系统，包括约0.02ml至约4.0ml浓度为约7.5mg / ml至约150mg / ml的甲氨蝶呤; 一种针辅助喷射喷射器，其包括容纳甲氨蝶呤的容器; 与所述容器相关联的注射出口构件; 注射辅助针，其联接到所述注射出口构件; 与容器相关联的击发机构; 与发射机构相关联的能量源; 以及与所述击发机构相关联的触发机构，其中所述针辅助喷射器被配置为从所述注射出口构件喷射所述甲氨蝶呤，使得针刺喷射的甲氨蝶呤的C max，T max和生物利用度落在约80％和用手动注射器输送的甲氨蝶呤的Cmax，Tmax和生物利用度的约125％。

9. 发明授权

US07776015B2 Needle assisted jet injector 有权
标题翻译：针辅助喷射器
公开(公告)号：US07776015B2
公开(公告)日：2010-08-17
申请号：US11002687
申请日：2004-12-03
申请人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
发明人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
IPC分类号： A61M37/00
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： A jet injection device with a fluid chamber in a housing member for holding about 0.02 ml to about 3 ml of a medicament. An injection-assisting needle has an injection end that extends from the housing for inserting into a patient to a depth of up to about 5 mm. A force-generating source is configured to apply a pressure reaching about 100-1000 psi to the medicament in the chamber to expel the medicament through the injecting end of the needle.
摘要翻译：一种喷射装置，其具有用于容纳约0.02ml至约3ml药物的壳体构件中的流体室。注射辅助针具有从壳体延伸以插入患者到达约5mm的深度的注射端。力产生源被配置为向腔室中的药物施加达到约100-1000psi的压力，以通过针的注射端排出药物。

10. 发明申请

US20090292240A1 TWO-STAGE RECONSTITUTING INJECTOR 有权
标题翻译：两级重建注射器
公开(公告)号：US20090292240A1
公开(公告)日：2009-11-26
申请号：US12299274
申请日：2007-05-02
申请人： Thomas E. KraMer , Peter L. Sadowski
发明人： Thomas E. KraMer , Peter L. Sadowski
IPC分类号： A61M5/31
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/2466 , A61M5/30 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/2073 , A61M2005/2474 , A61M2005/3125
摘要： An injector for injecting a medicament into a patient. The injector includes a container defining a first chamber, which contains a fluid therein, and a second chamber. The injector also includes an injection conduit configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.
摘要翻译：一种用于将药物注射到患者体内的注射器。喷射器包括限定在其中包含流体的第一室的容器和第二室。注射器还包括注射管道，其被配置用于将从容器中喷出的流体引导到患者体内。传送机构可由用户操作以在第一操作阶段将流体从第一腔室传送到第二腔室，并且击发机构可由使用者操作，用于通过喷射导管从第二腔室喷射流体第二阶段运作。一个能量源与击发机构相关联，以驱动第一和第二阶段的击发机构。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式