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1. 再颁专利

USRE44847E1 Needle assisted jet injector 有权
标题翻译：针辅助喷射器
公开(公告)号：USRE44847E1
公开(公告)日：2014-04-15
申请号：US13530974
申请日：2012-06-22
申请人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
发明人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
IPC分类号： A61M31/00
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： A needle assisted jet injector and method for jet injecting medicament are disclosed. In one embodiment of the injector, the needle is retractably located within an injector nozzle assembly. Upon activation of the force generating source, a portion of the needle extends past the nozzle assembly and penetrates the outer layer of skin to deliver the medicament via jet injection to a deeper region. After activation, the needle retracts back into the nozzle assembly. In another embodiment, the needle is fixed to the end of the nozzle assembly. In both embodiments, the length of the portion of the needle that penetrates the skin is less than 5 mm.
摘要翻译：公开了一种针刺辅助喷射器和喷射注射药物的方法。在注射器的一个实施例中，针可缩回地位于注射器喷嘴组件内。在激活力产生源时，针的一部分延伸穿过喷嘴组件并穿透皮肤的外层，以通过喷射注射将药物输送到更深的区域。激活后，针头缩回到喷嘴组件中。在另一个实施例中，针被固定到喷嘴组件的端部。在两个实施例中，穿过皮肤的针的部分的长度小于5mm。

2. 发明授权

US07744582B2 Needle assisted jet injector 有权
标题翻译：针辅助喷射器
公开(公告)号：US07744582B2
公开(公告)日：2010-06-29
申请号：US10861429
申请日：2004-06-07
申请人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
发明人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
IPC分类号： A61M31/00
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： A needle assisted jet injector and method for jet injecting medicament are disclosed. In one embodiment of the injector, the needle is retractably located within an injector nozzle assembly. Upon activation of the force generating source, a portion of the needle extends past the nozzle assembly and penetrates the outer layer of skin to deliver the medicament via jet injection to a deeper region. After activation, the needle retracts back into the nozzle assembly. In another embodiment, the needle is fixed to the end of the nozzle assembly. In both embodiments, the length of the portion of the needle that penetrates the skin is less than 5 mm.
摘要翻译：公开了一种针刺辅助喷射器和喷射注射药物的方法。在注射器的一个实施例中，针可缩回地位于注射器喷嘴组件内。在激活力产生源时，针的一部分延伸穿过喷嘴组件并穿透皮肤的外层，以通过喷射注射将药物输送到更深的区域。激活后，针头缩回到喷嘴组件中。在另一个实施例中，针被固定到喷嘴组件的端部。在两个实施例中，穿过皮肤的针的部分的长度小于5mm。

3. 发明授权

US07108675B2 Injection-assisting probe for medical injector assembly 有权
公开(公告)号：US07108675B2
公开(公告)日：2006-09-19
申请号：US10034926
申请日：2001-10-29
申请人： David M. Deboer , Peter L. Sadowski , Paul R. Lesch, Jr. , Claude L. Berman , Lucio Giambattista
发明人： David M. Deboer , Peter L. Sadowski , Paul R. Lesch, Jr. , Claude L. Berman , Lucio Giambattista
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/3007 , A61M5/3232
摘要： A probe and nozzle assembly for reducing the pressure at which a needleless injector must deliver medicament for proper delivery are disclosed. In one embodiment of the probe, the probe is retractably located within an injector nozzle assembly. Upon activation of the energy source a portion of the probe extends past the nozzle assembly to deliver the medicament through a discharge channel. After activation the probe retracts back into the nozzle assembly. In another embodiment, the probe is fixed to the end of the nozzle assembly. In both embodiments the ratio of discharge channel length to diameter is greater than 6/1.

4. 发明授权

US06309371B1 Injection-assisting probe for medical injector assembly 有权
标题翻译：用于医用注射器组件的注射辅助探针
公开(公告)号：US06309371B1
公开(公告)日：2001-10-30
申请号：US09359790
申请日：1999-07-26
申请人： David M. Deboer , Peter L. Sadowski , Paul R. Lesch, Jr. , Claude L. Berman , Lucio Giambattista
发明人： David M. Deboer , Peter L. Sadowski , Paul R. Lesch, Jr. , Claude L. Berman , Lucio Giambattista
IPC分类号： A61M530
CPC分类号： A61M5/30 , A61M5/3007 , A61M5/3232
摘要： A probe and nozzle assembly for reducing the pressure at which a needleless injector must deliver medicament for proper delivery are disclosed. In one embodiment of the probe, the probe is retractably located within an injector nozzle assembly. Upon activation of the energy source a portion of the probe extends past the nozzle assembly to deliver the medicament through a discharge channel. After activation the probe retracts back into the nozzle assembly. In another embodiment, the probe is fixed to the end of the nozzle assembly. In both embodiments the ratio of discharge channel length to diameter is greater than 6/1. The present invention also relates to nozzle assemblies with a discharge channel length to diameter ratio greater than 6/1.
摘要翻译：公开了一种用于降低无针注射器必须输送药物以适当递送的压力的探针和喷嘴组件。在探针的一个实施例中，探针可缩回地位于注射器喷嘴组件内。在激活能量源时，探针的一部分延伸穿过喷嘴组件以将药物输送通过排放通道。激活后，探头缩回到喷嘴组件中。在另一个实施例中，探针固定到喷嘴组件的端部。在两个实施例中，排出通道长度与直径的比率大于6/1。本发明还涉及排气通道长径比大于6/1的喷嘴组件。

5. 发明授权

US6123684A Loading mechanism for medical injector assembly 有权
标题翻译：医用注射器组装装载机构
公开(公告)号：US6123684A
公开(公告)日：2000-09-26
申请号：US359791
申请日：1999-07-26
申请人： David M. Deboer , Paul R. Lesch, Jr. , Sheldon J. Nelson
发明人： David M. Deboer , Paul R. Lesch, Jr. , Sheldon J. Nelson
IPC分类号： A61M5/178 , A61M5/30 , A61M5/00
CPC分类号： A61M5/1782 , A61M5/30 , A61M5/3007 , A61M5/31511 , A61M5/46 , A61M5/482
摘要： A loading mechanism for a medical injector assembly is disclosed. The loading mechanism according to the present invention includes a dosing sleeve slidingly joining first and second injector housing portions and having tabs at a first end and fixed to one of the first or second housing portions at a second end; and a sleeve retainer fixed to the other of the first or second housing portions and engageable with the tabs of the dosing sleeve at an engagement point to prevent movement of the dosing sleeve once an injector plunger is at a rear portion of an injector fluid chamber, wherein movement of the first housing portion away from the second housing portion moves the plunger in a second direction to load fluid into the fluid chamber and movement of the first housing portion toward the second housing portion moves the plunger in a first direction to remove the fluid from the fluid chamber. The disclosed loading mechanism facilitates filling the assembly with medicament and priming the assembly for use.
摘要翻译：公开了一种用于医用注射器组件的装载机构。根据本发明的加载机构包括：定量套筒，其滑动地接合第一和第二喷射器壳体部分，并且在第一端处具有突出部并且在第二端处固定到第一壳体部分或第二壳体部分中的一个; 以及套筒保持器，其固定到所述第一或第二壳体部分中的另一个，并且在接合点处可与所述计量套筒的所述突片接合，以防止一旦注射器柱塞位于注射器流体室的后部处时所述计量套管的运动，其中所述第一壳体部分远离所述第二壳体部分的运动使所述柱塞在第二方向上移动以将流体加载到所述流体室中，并且所述第一壳体部分朝向所述第二壳体部分的运动沿着第一方向移动所述柱塞以移除所述流体从流体室。所公开的装载机构有助于用药物填充组件并启动组件以供使用。

6. 发明授权

US06565553B2 Needle assisted jet injector 有权
标题翻译：针辅助喷射器
公开(公告)号：US06565553B2
公开(公告)日：2003-05-20
申请号：US10062652
申请日：2002-01-31
申请人： Peter L. Sadowski , David M. DeBoer , Claude L. Berman , Paul R. Lesch, Jr.
发明人： Peter L. Sadowski , David M. DeBoer , Claude L. Berman , Paul R. Lesch, Jr.
IPC分类号： A61M3100
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： The invention relates to methods and devices for delivering medicament by jet injection to an injection site in a patient. The method includes inserting a needle into an insertion point, wherein the needle has a length of less than 5 mm and is operatively associated with an orifice in a nozzle assembly in fluid communication with an ampule chamber containing the medicament. The needle extends less than about 5 mm from the nozzle assembly orifice when the medicament is expelled. Next, a force generating mechanism is activated, and a pressure wall member that is operatively associated with the force generating member moves in response to the activation of the force generating mechanism at a speed sufficient to jet inject the medicament from the ampule chamber through the orifice and needle under a pressure of less than about 4000 psi to deliver a substantial portion of the medicament through the needle and past the insertion point to the injection site. The needle tip maybe part of a retractable needle of a jet injection device, or is part of a fixed needle of a jet injection device.
摘要翻译：本发明涉及通过射流注射将药物输送到患者的注射部位的方法和装置。该方法包括将针插入插入点，其中针具有小于5mm的长度并且与喷嘴组件中的孔口可操作地相关联，该喷嘴组件与容纳药物的安瓿室流体连通。当药物被排出时，针从喷嘴组件孔口延伸小于约5mm。接下来，启动力产生机构，并且与力产生构件可操作地相关联的压力壁构件响应于力产生机构的激活而移动，其速度足以喷射从安瓿室喷射药物通过孔和针在小于约4000psi的压力下，以将大部分药物通过针输送并穿过插入点至注射部位。针尖可以是喷射装置的可缩回针的一部分，或者是喷射装置的固定针的一部分。

7. 发明授权

US5533798A Lock system for casegoods 失效
标题翻译：锁定系统
公开(公告)号：US5533798A
公开(公告)日：1996-07-09
申请号：US138638
申请日：1993-10-15
申请人： Thomas G. Feldpausch , Phillip D. Carino , Frederick S. Faiks , David M. DeBoer , Samuel J. Ellison , Daniel N. Siegrist
发明人： Thomas G. Feldpausch , Phillip D. Carino , Frederick S. Faiks , David M. DeBoer , Samuel J. Ellison , Daniel N. Siegrist
IPC分类号： E05B47/00 , E05B53/00 , E05B65/46
CPC分类号： E05B65/463 , E05B53/003 , E05B65/462 , E05B47/00 , E05B65/466 , Y10T292/0841
摘要： A lock system for casegoods, such as desks, cabinets, storage units, wardrobes and the like, includes an elongated, flexible tape or lock member having a plurality of spaced lock studs positioned thereon. A lock actuator moves the tape between unlocked and locked positions. Catches are mounted on the drawers, doors and the like of the article. When the flexible tape is moved to the locked position, the lock studs block or prevent opening movement of the drawers or doors due to contact with the catches. The flexible tape is routed through channels or other mounting structure formed in panels and tops of the article of furniture. An interlock mechanism, which may be integrated with the lock member, includes a lock lever, a cable attached to the lock lever and a plurality of interlock cams. Control members on the drawers rotate the cams to take up the cable causing the interlock lever to pivot and engage the lock member, thereby moving the lock member to a locked position. The interlock mechanism may include a plurality of force generating members which act upon the lock member upon the opening of a drawer. The force generated by each of the members is insufficient in and of itself to move the tape to the locked position. The force generated by two of the members is, however, sufficient to move the tape to a locked position, thereby preventing opening of a second drawer.
摘要翻译：用于盒子的锁定系统，例如书桌，橱柜，存储单元，衣柜等，包括细长的，柔性的带或锁定构件，其具有定位在其上的多个间隔开的锁定螺柱。锁定致动器将胶带移动到解锁位置和锁定位置之间。卡扣安装在物品的抽屉，门等上。当柔性带移动到锁定位置时，由于与卡扣的接触，锁定螺栓阻挡或阻止抽屉或门的打开运动。柔性带通过通道或形成在家具制品的顶部和顶部的其它安装结构。可以与锁定构件一体化的互锁机构包括锁定杆，连接到锁定杆的电缆和多个互锁凸轮。抽屉上的控制构件旋转凸轮以吸收电缆，使得互锁杆枢转并接合锁定构件，从而将锁定构件移动到锁定位置。互锁机构可以包括多个力产生构件，其在抽屉的打开时作用在锁定构件上。由每个构件产生的力本身不足以将带移动到锁定位置。然而，由两个构件产生的力足以将带移动到锁定位置，从而防止第二抽屉的打开。

8. 再颁专利

USRE44846E1 Needle assisted jet injector 有权
标题翻译：针辅助喷射器
公开(公告)号：USRE44846E1
公开(公告)日：2014-04-15
申请号：US13531023
申请日：2012-06-22
申请人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
发明人： Peter L. Sadowski , David M. Deboer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
IPC分类号： A61M37/00
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： A jet injection device with a fluid chamber in a housing member for holding about 0.02 ml to about 3 ml of a medicament. An injection-assisting needle has an injection end that extends from the housing for inserting into a patient to a depth of up to about 5 mm. A force-generating source is configured to apply a pressure reaching about 100-1000 psi to the medicament in the chamber to expel the medicament through the injecting end of the needle.
摘要翻译：一种喷射装置，其具有用于容纳约0.02ml至约3ml药物的壳体构件中的流体室。注射辅助针具有从壳体延伸以插入患者到达约5mm的深度的注射端。力产生源被配置为向腔室中的药物施加达到约100-1000psi的压力，以通过针的注射端排出药物。

9. 发明授权

US06746429B2 Needle assisted jet injector 有权
公开(公告)号：US06746429B2
公开(公告)日：2004-06-08
申请号：US09779603
申请日：2001-02-09
申请人： Peter L. Sadowski , David M. DeBoer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
发明人： Peter L. Sadowski , David M. DeBoer , Claude L. Berman , Paul R. Lesch, Jr. , Margaret L. Holland
IPC分类号： A61M524
CPC分类号： A61M5/326 , A61M5/002 , A61M5/20 , A61M5/24 , A61M5/2425 , A61M5/2466 , A61M5/282 , A61M5/288 , A61M5/30 , A61M5/3202 , A61M5/3232 , A61M5/3243 , A61M5/3286 , A61M5/349 , A61M2005/3247 , A61M2205/583
摘要： A needle assisted jet injector and method for jet injecting medicament are disclosed. In one embodiment of the injector, the needle is retractably located within an injector nozzle assembly. Upon activation of the force generating source, a portion of the needle extends past the nozzle assembly and penetrates the outer layer of skin to deliver the medicament via jet injection to a deeper region. After activation, the needle retracts back into the nozzle assembly. In another embodiment, the needle is fixed to the end of the nozzle assembly. In both embodiments, the length of the portion of the needle that penetrates the skin is less than 5 mm.

10. 发明授权

US5709442A Lock system for casegoods 失效
公开(公告)号：US5709442A
公开(公告)日：1998-01-20
申请号：US628551
申请日：1996-04-10
申请人： Thomas G. Feldpausch , Phillip D. Carino , Frederick S. Faiks , David M. DeBoer , Samuel J. Ellison , Daniel N. Siegrist
发明人： Thomas G. Feldpausch , Phillip D. Carino , Frederick S. Faiks , David M. DeBoer , Samuel J. Ellison , Daniel N. Siegrist
IPC分类号： E05B47/00 , E05B53/00 , E05B65/46
CPC分类号： E05B65/463 , E05B53/003 , E05B65/462 , E05B47/00 , E05B65/466 , Y10T292/0841
摘要： A lock system for casegoods, such as desks, cabinets, storage units, wardrobes and the like, includes an elongated, flexible tape or lock member having a plurality of spaced lock studs positioned thereon. A lock actuator moves the tape between unlocked and locked positions. Catches are mounted on the drawers, doors and the like of the article. When the flexible tape is moved to the locked position, the lock studs block or prevent opening movement of the drawers or doors due to contact with the catches. The flexible tape is routed through channels or other mounting structure formed in panels and tops of the article of furniture. An interlock mechanism, which may be integrated with the lock member, includes a lock lever, a cable attached to the lock lever and a plurality of interlock cams. Control members on the drawers rotate the cams to take up the cable causing the interlock lever to pivot and engage the lock member, thereby moving the lock member to a locked position. The interlock mechanism may include a plurality of force generating members which act upon the lock member upon the opening of a drawer. The force generated by each of the members is insufficient in and of itself to move the tape to the locked position. The force generated by two of the members is, however, sufficient to move the tape to a locked position, thereby preventing opening of a second drawer.

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