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1. 发明申请

US20110082353A1 Implanting Optical Cavity Structures 有权
标题翻译：植入光腔结构
公开(公告)号：US20110082353A1
公开(公告)日：2011-04-07
申请号：US12968115
申请日：2010-12-14
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Richard H. Bruce , Noble M. Johnson
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Richard H. Bruce , Noble M. Johnson
IPC分类号： A61B5/00
CPC分类号： G01N21/03 , A61B5/0075 , A61B5/0084 , A61B5/14532 , A61B5/1459 , G01N21/0303 , G01N21/274 , G01N21/31
摘要： An implantable product includes an optical cavity structure with first and second parts, each of which can operate as an optical cavity. The first part includes a container with at least one opening through which bodily fluid can transfer between the container's interior and exterior when the product is implanted in a body. The second part includes a container that is closed and contains a reference fluid. The implantable product can also include one or both of a light source component and a photosensing component. Photosensed quantities from the first part's output light can be adjusted based on photosensed quantities from the second part's output light. Both parts can have their light interface surfaces aligned so that they both receive input light from a light source component and both provide output light to a photosensing component.
摘要翻译：可植入产品包括具有第一和第二部分的光学腔结构，每个部分可以作为光腔工作。第一部分包括具有至少一个开口的容器，当产品植入体内时，体液可以通过该开口在容器的内部和外部之间转移。第二部分包括封闭的容器并且包含参考流体。可植入产品还可以包括光源组件和感光组件中的一个或两个。可以根据第二部分输出指示灯的光线数量来调整第一部分输出光的照片数量。两个部件可以使它们的光接口表面对准，使得它们都接收来自光源部件的输入光并且都向光敏部件提供输出光。

2. 发明授权

US07741147B2 Method of field-controlled diffusion and devices formed thereby 失效
标题翻译：现场控制扩散方法及由此形成的器件
公开(公告)号：US07741147B2
公开(公告)日：2010-06-22
申请号：US11615331
申请日：2006-12-22
申请人： Peter Kiesel , Oliver Schmidt
发明人： Peter Kiesel , Oliver Schmidt
IPC分类号： H01L21/00 , H01L21/16 , H01L21/331 , H01L21/326
CPC分类号： H01L29/66848 , H01L29/22 , H01L29/66143 , H01L31/108 , H01L31/1828 , Y02E10/543 , Y02P70/521
摘要： A technique for creating high quality Schottky barrier devices in doped (e.g., Li+) crystalline metal oxide (e.g., ZnO) comprises field-controlled diffusion of mobile dopant atoms within the metal oxide crystal lattice. When heated (e.g., above 550 K) in the presence of an electric field (e.g., bias to ground of +/−50 V) the dopant atoms are caused to collect to form an ohmic contact, leaving a depletion region. The size of the depletion region controls the thickness of the Schottky barrier. Metal-semiconductor junction devices such as diodes, photo-diodes, photo-detectors, MESFETs, etc. may thereby be fabricated.
摘要翻译：在掺杂（例如Li +）结晶金属氧化物（例如ZnO）中产生高质量肖特基势垒器件的技术包括在金属氧化物晶格内的移动掺杂剂原子的场控扩散。当在存在电场（例如，+/- 50V的接地偏压）的情况下加热（例如，高于550K）时，引起掺杂剂原子以形成欧姆接触，留下耗尽区。耗尽区的大小控制肖特基势垒的厚度。因此可以制造诸如二极管，光电二极管，光电检测器，MESFET等的金属 - 半导体结器件。

3. 发明授权

US07633629B2 Tuning optical cavities 有权
标题翻译：调谐光腔
公开(公告)号：US07633629B2
公开(公告)日：2009-12-15
申请号：US11702321
申请日：2007-02-05
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
IPC分类号： G01B9/02
CPC分类号： G01J3/26 , G01N21/45 , G01N2021/451 , G02B26/001
摘要： A tunable optical cavity can be tuned by relative movement between two reflection surfaces, such as by deforming elastomer spacers connected between mirrors or other light-reflective components that include the reflection surfaces. The optical cavity structure includes an analyte region in its light-transmissive region, and presence of analyte in the analyte region affects output light when the optical cavity is tuned to a set of positions. Electrodes that cause deformation of the spacers can also be used to capacitively sense the distance between them. Control circuitry that provides tuning signals can cause continuous movement across a range of positions, allowing continuous photosensing of analyte-affected output light by a detector.
摘要翻译：可调光学腔可以通过两个反射表面之间的相对运动进行调节，例如通过变形连接在反射镜之间的弹性体隔离物或包括反射表面的其它光反射部件。光腔结构包括其透光区域中的分析物区域，并且当光学腔被调谐到一组位置时，分析物区域中的分析物的存在影响输出光。导致间隔物变形的电极也可用于电容地感测它们之间的距离。提供调谐信号的控制电路可以在一定范围的位置上引起连续的运动，从而允许由检测器对被分析物影响的输出光进行连续光敏。

4. 发明授权

US07471399B2 Photosensing optical cavity output light 有权
公开(公告)号：US07471399B2
公开(公告)日：2008-12-30
申请号：US11702250
申请日：2007-02-05
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler
IPC分类号： G01B9/02
CPC分类号： G01N21/031 , B01L3/5085 , G01J3/26 , G01N2021/391
摘要： An optical cavity, such as a laser or transmissive cavity, that can contain an analyte provides a different intensity-energy function with analyte present than when absent. The intensity-energy functions can, for example, include respective peaks that are different in at least one of central energy, amplitude, contrast, and full width half maximum (FWHM) (or other intermediate intensity width). Each intensity-energy function can include a set of modes in which the optical cavity provides output light. A laterally varying transmission component, such as a layered linearly varying filter, responds to the intensity-energy functions by providing different laterally varying energy distributions to a photosensing IC, and the distributions are also different, such as in position, size, or intensity. In response, the photosensing IC provides sensing results that are also different. The sensing results can be used to obtain information about the analyte, such as its refractive index or absorption coefficient.

5. 发明授权

US07432526B2 Surface-passivated zinc-oxide based sensor 失效
标题翻译：表面钝化的氧化锌基传感器
公开(公告)号：US07432526B2
公开(公告)日：2008-10-07
申请号：US11314881
申请日：2005-12-20
申请人： Christian G. Van de Walle , Peter Kiesel , Oliver Schmidt
发明人： Christian G. Van de Walle , Peter Kiesel , Oliver Schmidt
IPC分类号： H01L29/10
CPC分类号： G01N27/414 , B82Y10/00 , B82Y15/00 , B82Y30/00 , H01L29/225
摘要： A semiconductor device has a heterostructure including a first layer of semiconductor oxide material. A second layer of semiconductor oxide material is formed on the first layer of semiconductor oxide material such that a two dimensional electron gas builds up at an interface between the first and second materials. A passivation layer on the outer surface stabilizes the structure. The device also has a source contact and a drain contact.
摘要翻译：半导体器件具有包括第一半导体氧化物材料层的异质结构。半导体氧化物材料的第二层形成在第一半导体氧化物层上，使得二维电子气在第一和第二材料之间的界面积聚。外表面上的钝化层使结构稳定。该器件还具有源触点和漏极触点。

6. 发明申请

US20080186508A1 Tuning optical cavities 有权
标题翻译：调谐光腔
公开(公告)号：US20080186508A1
公开(公告)日：2008-08-07
申请号：US11702321
申请日：2007-02-05
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
IPC分类号： G01B9/02
CPC分类号： G01J3/26 , G01N21/45 , G01N2021/451 , G02B26/001
摘要： A tunable optical cavity can be tuned by relative movement between two reflection surfaces, such as by deforming elastomer spacers connected between mirrors or other light-reflective components that include the reflection surfaces. The optical cavity structure includes an analyte region in its light-transmissive region, and presence of analyte in the analyte region affects output light when the optical cavity is tuned to a set of positions. Electrodes that cause deformation of the spacers can also be used to capacitively sense the distance between them. Control circuitry that provides tuning signals can cause continuous movement across a range of positions, allowing continuous photosensing of analyte-affected output light by a detector.
摘要翻译：可调光学腔可以通过两个反射表面之间的相对运动进行调节，例如通过变形连接在反射镜之间的弹性体隔离物或包括反射表面的其它光反射部件。光腔结构包括其透光区域中的分析物区域，并且当光学腔被调谐到一组位置时，分析物区域中的分析物的存在影响输出光。导致间隔物变形的电极也可用于电容地感测它们之间的距离。提供调谐信号的控制电路可以在一定范围的位置上引起连续的运动，从而允许由检测器对被分析物影响的输出光进行持续的光敏。

7. 发明申请

US20080181827A1 Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity 有权
标题翻译：实现空间调制激发或发射的方法和系统，用于增强灵敏度的粒子表征
公开(公告)号：US20080181827A1
公开(公告)日：2008-07-31
申请号：US11698409
申请日：2007-01-26
申请人： Michael Bassler , Peter Kiesel , Oliver Schmidt , Noble M. Johnson
发明人： Michael Bassler , Peter Kiesel , Oliver Schmidt , Noble M. Johnson
IPC分类号： A61L2/28 , G01N33/00 , G01N21/75 , G01N21/76
CPC分类号： G01N21/6486 , G01N15/1427 , G01N15/147 , G01N2015/1447 , G01N2015/1454 , Y10T436/143333 , Y10T436/17
摘要： A method and system for using spatially modulated excitation/emission and relative movement between a particle (cell, molecule, aerosol, . . . ) and an excitation/emission pattern are provided. In at least one form, an interference pattern of the excitation light with submicron periodicity perpendicular to the particle flow is used. As the particle moves along the pattern, emission is modulated according to the speed of the particle and the periodicity of the stripe pattern. A single detector, which records the emission over a couple of stripes, can be used. The signal is recorded with a fast detector read-out in order to capture the “blinking” of the particles while they are moving through the excitation pattern. This concept enables light detection with high signal-to-noise ratio and high spatial resolution without the need of expensive and bulky optics.
摘要翻译：提供了使用空间调制的激发/发射和颗粒（细胞，分子，气溶胶等）和激发/发射图案之间的相对运动的方法和系统。在至少一种形式中，使用具有垂直于颗粒流的亚微米周期的激发光的干涉图案。当颗粒沿着图案移动时，根据颗粒的速度和条纹图案的周期性来调制发射。可以使用记录两条条纹上的发射的单个检测器。用快速检测器读出来记录信号，以便在它们移动通过激励图案时捕获颗粒的“闪烁”。这个概念能够实现高信噪比和高空间分辨率的光检测，而不需要昂贵和庞大的光学元件。

8. 发明申请

US20080013877A1 METHOD AND APPARATUS FOR IMPROVED LIGHT DISTRIBUTION IN AN ANTI-RESONANT WAVEGUIDE SENSOR 有权
标题翻译：用于改进光分布在抗共振波导传感器中的方法和装置
公开(公告)号：US20080013877A1
公开(公告)日：2008-01-17
申请号：US11777976
申请日：2007-07-13
申请人： Oliver Schmidt , Michael Bassler , Peter Kiesel , Patrick Maeda , Noble Johnson
发明人： Oliver Schmidt , Michael Bassler , Peter Kiesel , Patrick Maeda , Noble Johnson
IPC分类号： G02B6/00
CPC分类号： G02B6/10 , G01N21/03 , G01N21/0303 , G01N21/33 , G01N21/35 , G01N21/3577 , G01N21/64 , G01N21/65 , G01N2021/651 , G02B6/032 , G02B6/34
摘要： An improved method of analyzing target analytes in a sample is described. The method is based on creating an approximately homogeneous distribution of light in an anti-resonant guided optical waveguide to improve light-target interaction in a target-containing medium. The light-target interaction can be monitored by many different means to determine characteristics of the target analyte.
摘要翻译：描述了一种分析样品中目标分析物的改进方法。该方法基于在反谐振引导光波导中产生大致均匀的光分布，以改善含靶介质中的光 - 目标相互作用。光靶相互作用可以通过许多不同的手段来监测，以确定目标分析物的特征。

9. 发明授权

US07248361B2 Fluorescence reader based on anti-resonant waveguide excitation 有权
标题翻译：基于反谐振波导激发的荧光读数器
公开(公告)号：US07248361B2
公开(公告)日：2007-07-24
申请号：US11315797
申请日：2005-12-22
申请人： Peter Kiesel , Oliver Wolst , Michael Kneissl , Huangpin Ben Hsieh , Oliver Schmidt
发明人： Peter Kiesel , Oliver Wolst , Michael Kneissl , Huangpin Ben Hsieh , Oliver Schmidt
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01N21/03 , G01N21/0303 , G01N21/05 , G01N21/31 , G01N21/33 , G01N21/35 , G01N21/3504 , G01N21/3577 , G01N21/3581 , G01N21/59 , G01N21/64 , G01N21/6456 , G01N2021/0346 , G01N2021/058 , G01N2021/513 , G01N2021/6467 , G01N2021/6469 , G01N2021/6493
摘要： A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a second index of refraction, and the substrate has a third index of refraction. The second index of refraction, and the third index of refraction are both greater than the first index of refraction. A detection device of the system includes a low power light source used to direct light into the sample and generate an anti-resonant optical mode in the sample, and an analyzing system to detect the interaction of the light propagating in the sample.
摘要翻译：一种样本检测系统，包括反谐振波导，包括具有第一折射率的样品，顶层和围绕样品的基底，其中顶层具有第二折射率，并且所述基底具有第三指数折射。第二折射率和第三折射率均大于第一折射率。该系统的检测装置包括用于将光引入样品并在样品中产生反谐振光学模式的低功率光源，以及用于检测在样品中传播的光的相互作用的分析系统。

10. 发明申请

US20070147728A1 Providing light to channels or portions 有权
标题翻译：向通道或部分提供光
公开(公告)号：US20070147728A1
公开(公告)日：2007-06-28
申请号：US11316660
申请日：2005-12-22
申请人： Oliver Schmidt , Setu Mohta , Peter Kiesel
发明人： Oliver Schmidt , Setu Mohta , Peter Kiesel
IPC分类号： G02B6/12
CPC分类号： G01N21/05 , B01L3/502715 , B01L2300/0654 , B01L2300/0816 , B01L2300/168 , G01N21/0303 , G01N21/64 , G01N21/65 , G01N2021/0346
摘要： A fluidity structure includes a channel, a portion of which can contain fluid. Light can propagate in the portion, such as in response to illumination. The refractive index of material at the portion's boundary can be higher than that of the fluid, and more than approximately 10% of intensity of light propagating longitudinally occurs in the fluid, possibly approximately 90%. An IC can be positioned along the portion, with a set of cells of a photosensor array on the IC sensing photons emanating in response to the propagating light. The light can enter through a light-transmissive component along the channel's boundary, then pass obliquely through a portion of the channel that contains air before passing through a bounding component and obliquely into the portion that can contain fluid. The light can couple to an anti-resonant waveguide mode.
摘要翻译：流动性结构包括通道，其一部分可以容纳流体。光可以在该部分中传播，例如响应照明。在该部分边界的材料的折射率可以高于流体的折射率，并且大约10％的光纵向传播的强度发生在流体中，可能约为90％。 IC可以沿着该部分定位，其中一组光电传感器阵列的单元被感测响应于传播光发出的光子。光可以沿着通道的边界通过透光部件进入，然后在通过边界部件之前倾斜地穿过包含空气的通道的一部分，并倾斜地穿过可容纳流体的部分。光可以耦合到反谐振波导模式。

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