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1. 发明授权

US07771940B2 Methods of detecting a plurality of sequence specific DNA binding proteins with oligonucleotide detection duplexes 失效
标题翻译：用寡核苷酸检测双链体检测多个序列特异性DNA结合蛋白的方法
公开(公告)号：US07771940B2
公开(公告)日：2010-08-10
申请号：US11549830
申请日：2006-10-16
申请人： Peter A. Clausen , David P. Carlson , James G. Lazar
发明人： Peter A. Clausen , David P. Carlson , James G. Lazar
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： C12Q1/44 , G01N33/5308 , G01N33/6875 , G01N2333/4703 , G01N2333/922
摘要： Compositions and methods are provided for detecting and measuring DNA-binding proteins. The compositions and methods permit the simultaneous or near-simultaneous detection of multiple DNA-binding proteins in a multiplex or array format, and can be used to generate profiles of DNA binding activity by proteins, specifically, transcription factors. Multiple protein-DNA binding events in a single sample may be detected and quantitated in a high-throughput format.
摘要翻译：提供用于检测和测量DNA结合蛋白的组合物和方法。组合物和方法允许以多重或阵列形式同时或几乎同时检测多个DNA结合蛋白，并且可用于通过蛋白质，特别是转录因子产生DNA结合活性的谱。可以以高通量格式检测和定量单个样品中的多个蛋白质 - DNA结合事件。

2. 发明申请

US20090208927A1 Methods of detecting sequence-specific DNA binding proteins 失效
标题翻译：检测序列特异性DNA结合蛋白的方法
公开(公告)号：US20090208927A1
公开(公告)日：2009-08-20
申请号：US11549830
申请日：2006-10-16
申请人： Peter A. Clausen , David P. Carlson , James G. Lazar
发明人： Peter A. Clausen , David P. Carlson , James G. Lazar
IPC分类号： C12Q1/68 , G01N33/566
CPC分类号： C12Q1/44 , G01N33/5308 , G01N33/6875 , G01N2333/4703 , G01N2333/922
摘要： Compositions and methods are provided for detecting and measuring DNA-binding proteins. The compositions and methods permit the simultaneous or near-simultaneous detection of multiple DNA-binding proteins in a multiplex or array format, and can be used to generate profiles of DNA binding activity by proteins, specifically, transcription factors. Multiple protein-DNA binding events in a single sample may be detected and quantitated in a high-throughput, format.
摘要翻译：提供用于检测和测量DNA结合蛋白的组合物和方法。组合物和方法允许以多重或阵列形式同时或几乎同时检测多个DNA结合蛋白，并且可用于通过蛋白质，特别是转录因子产生DNA结合活性的谱。可以以高通量，格式检测和定量单个样品中的多个蛋白质 - DNA结合事件。

3. 发明授权

US07122317B2 Multiplex method of detecting sequence-specific DNA binding proteins using detection duplexes comprising unmodified nucleic acid sequences as capture tags 失效
标题翻译：使用包含未修饰的核酸序列作为捕获标签的检测双链体检测序列特异性DNA结合蛋白的多重法
公开(公告)号：US07122317B2
公开(公告)日：2006-10-17
申请号：US10400670
申请日：2003-03-28
申请人： Peter A. Clausen , David P. Carlson , James G. Lazar
发明人： Peter A. Clausen , David P. Carlson , James G. Lazar
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： C12Q1/44 , G01N33/5308 , G01N33/6875 , G01N2333/4703 , G01N2333/922
摘要： Compositions and methods are provided for detecting and measuring DNA-binding proteins. The compositions and methods permit the simultaneous or near-simultaneous detection of multiple DNA-binding proteins in a multiplex or array format, and can be used to generate profiles of DNA binding activity by proteins, specifically, transcription factors. Multiple protein-DNA binding events in a single sample may be detected and quantitated in a high-throughput format.
摘要翻译：提供用于检测和测量DNA结合蛋白的组合物和方法。组合物和方法允许以多重或阵列形式同时或几乎同时检测多个DNA结合蛋白，并且可用于通过蛋白质，特别是转录因子产生DNA结合活性的谱。可以以高通量格式检测和定量单个样品中的多个蛋白质 - DNA结合事件。

4. 发明授权

US08078436B2 Aerial roof estimation systems and methods 有权
标题翻译：空中屋顶估计系统和方法
公开(公告)号：US08078436B2
公开(公告)日：2011-12-13
申请号：US12253092
申请日：2008-10-16
申请人： Chris Pershing , David P. Carlson
发明人： Chris Pershing , David P. Carlson
IPC分类号： G06F7/60 , G06F17/10
CPC分类号： G06T17/10 , G06F17/5004 , G06Q10/06313 , G06Q30/02 , G06Q30/0283 , G06T7/32 , G06T7/337 , G06T11/60 , G06T17/20 , G06T19/20 , G06T2200/08 , G06T2207/10032 , G06T2207/30184 , G06T2210/04 , G06T2219/004
摘要： Methods and systems for roof estimation are described. Example embodiments include a roof estimation system, which generates and provides roof estimate reports annotated with indications of the size, geometry, pitch and/or orientation of the roof sections of a building. Generating a roof estimate report may be based on one or more aerial images of a building. In some embodiments, generating a roof estimate report of a specified building roof may include generating a three-dimensional model of the roof, and generating a report that includes one or more views of the three-dimensional model, the views annotated with indications of the dimensions, area, and/or slope of sections of the roof. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：描述屋顶估计的方法和系统。示例性实施例包括屋顶估计系统，其生成并提供用建筑物的屋顶部分的尺寸，几何形状，俯仰和/或取向的指示注释的屋顶估计报告。生成屋顶估计报告可以基于建筑物的一个或多个空中图像。在一些实施例中，生成指定建筑物屋顶的屋顶估计报告可以包括生成屋顶的三维模型，以及生成包括三维模型的一个或多个视图的报告，所述视图用屋顶部分的尺寸，面积和/或坡度。提供本摘要以符合要求摘要的规则，并提交其意图是不会用于解释或限制权利要求书的范围或含义。

5. 发明申请

US20090132436A1 AERIAL ROOF ESTIMATION SYSTEMS AND METHODS 有权
标题翻译：航空屋顶估计系统和方法
公开(公告)号：US20090132436A1
公开(公告)日：2009-05-21
申请号：US12253092
申请日：2008-10-16
申请人： Chris Pershing , David P. Carlson
发明人： Chris Pershing , David P. Carlson
IPC分类号： G06Q10/00 , G06K9/62
CPC分类号： G06T17/10 , G06F17/5004 , G06Q10/06313 , G06Q30/02 , G06Q30/0283 , G06T7/32 , G06T7/337 , G06T11/60 , G06T17/20 , G06T19/20 , G06T2200/08 , G06T2207/10032 , G06T2207/30184 , G06T2210/04 , G06T2219/004
摘要： Methods and systems for roof estimation are described. Example embodiments include a roof estimation system, which generates and provides roof estimate reports annotated with indications of the size, geometry, pitch and/or orientation of the roof sections of a building. Generating a roof estimate report may be based on one or more aerial images of a building. In some embodiments, generating a roof estimate report of a specified building roof may include generating a three-dimensional model of the roof, and generating a report that includes one or more views of the three-dimensional model, the views annotated with indications of the dimensions, area, and/or slope of sections of the roof. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：描述屋顶估计的方法和系统。示例性实施例包括屋顶估计系统，其生成并提供用建筑物的屋顶部分的尺寸，几何形状，俯仰和/或取向的指示注释的屋顶估计报告。生成屋顶估计报告可以基于建筑物的一个或多个空中图像。在一些实施例中，生成指定建筑物屋顶的屋顶估计报告可以包括生成屋顶的三维模型，以及生成包括三维模型的一个或多个视图的报告，所述视图用屋顶部分的尺寸，面积和/或坡度。提供本摘要以符合要求摘要的规则，并提交其意图是不会用于解释或限制权利要求书的范围或含义。

6. 发明授权

US5316908A Size markers for electrophoretic analysis of DNA 失效
标题翻译：用于电泳分析DNA的大小标记
公开(公告)号：US5316908A
公开(公告)日：1994-05-31
申请号：US522406
申请日：1990-07-13
申请人： David P. Carlson , Paul C. Watkins , Leonard Klevan
发明人： David P. Carlson , Paul C. Watkins , Leonard Klevan
IPC分类号： C12Q1/68 , C12Q1/70
CPC分类号： C12Q1/70 , C12Q1/68 , C12Q1/683 , Y10S435/967 , Y10T436/10
摘要： The present invention discloses a DNA marker ladder useful in Southern blot hybridizations. The ladder is made up of pooled DNA restriction endonuclease digests, where each restriction digest contains at least one fragment complementary to a probe and at least one fragment not complementary to the probe. The regions of complementarity between the probe and the complementary fragments are double-stranded segments of the fragments. The ladder is characterized by an approximately even spacing of bands, resulting from choosing fragments having an logarithmic size distribution. Kits incorporating this ladder and a probe or means for making a probe or a probe and a means for labeling a probe are also disclosed.
摘要翻译：本发明公开了一种可用于Southern印迹杂交的DNA标记梯。梯子由合并的DNA限制性内切核酸酶消化物组成，其中每个限制性消化物含有至少一个与探针互补的片段和至少一个与探针不互补的片段。探针和互补片段之间的互补区域是片段的双链片段。梯形图的特征在于从选择具有对数尺寸分布的碎片产生的带的大致均匀间隔。还公开了包含该梯子的试剂盒和用于制备探针或探针的探针或装置以及用于标记探针的装置。

7. 发明授权

US4009031A Diffusion transfer image-receiving element having polyvinylpyridine layer treated with hydrophilic colloid/ammonia solution 失效
标题翻译：具有用亲水胶体/氨溶液处理的聚乙烯基吡啶层的扩散转印图像接收元件
公开(公告)号：US4009031A
公开(公告)日：1977-02-22
申请号：US584488
申请日：1975-06-06
申请人： David P. Carlson , Thomas R. Keenan , Douglas L. Marks
发明人： David P. Carlson , Thomas R. Keenan , Douglas L. Marks
IPC分类号： G03C8/52 , G03C5/54 , B44D1/09 , G03C1/40 , G03C7/00
CPC分类号： G03C8/52 , Y10S430/142 , Y10T428/31855
摘要： Coating a solution comprising a hydrophilic colloid and ammonia over a receiving layer comprising polyvinylpyridine in an image-receiving element of a photographic film unit significantly reduces haze and facilitates the separation of the image-receiving element from the remainder of the film unit subsequent to diffusion transfer processing.
摘要翻译：在摄影胶片单元的图像接收元件中将包含亲水胶体和氨的溶液涂覆在包含聚乙烯基吡啶的接收层上，显着降低雾度并促进图像接收元件与扩散转移后的其余部分分离处理。

8. 发明授权

US08670961B2 Aerial roof estimation systems and methods 有权
标题翻译：空中屋顶估计系统和方法
公开(公告)号：US08670961B2
公开(公告)日：2014-03-11
申请号：US13287954
申请日：2011-11-02
申请人： Chris Pershing , David P. Carlson
发明人： Chris Pershing , David P. Carlson
IPC分类号： G06F17/50 , G06F7/60 , G06F17/10
CPC分类号： G06T17/10 , G06F17/5004 , G06Q10/06313 , G06Q30/02 , G06Q30/0283 , G06T7/32 , G06T7/337 , G06T11/60 , G06T17/20 , G06T19/20 , G06T2200/08 , G06T2207/10032 , G06T2207/30184 , G06T2210/04 , G06T2219/004
摘要： Methods and systems for roof estimation are described. Example embodiments include a roof estimation system, which generates and provides roof estimate reports annotated with indications of the size, geometry, pitch and/or orientation of the roof sections of a building. Generating a roof estimate report may be based on one or more aerial images of a building. The slope and orientation images are typically oblique perspective views and top plan views of the buildings in the area. In some embodiments, generating a roof estimate report of a specified building roof may include generating a three-dimensional model of the roof, and generating a report that includes one or more views of the three-dimensional model, the views annotated with indications of the dimensions, area, and/or slope of sections of the roof. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：描述屋顶估计的方法和系统。示例性实施例包括屋顶估计系统，其生成并提供用建筑物的屋顶部分的尺寸，几何形状，俯仰和/或取向的指示注释的屋顶估计报告。生成屋顶估计报告可以基于建筑物的一个或多个空中图像。倾斜和定向图像通常是该区域的建筑物的倾斜透视图和俯视图。在一些实施例中，生成指定建筑物屋顶的屋顶估计报告可以包括生成屋顶的三维模型，以及生成包括三维模型的一个或多个视图的报告，所述视图用屋顶部分的尺寸，面积和/或坡度。提供本摘要以符合要求摘要的规则，并提交其意图是不会用于解释或限制权利要求书的范围或含义。

9. 发明申请

US20120170797A1 AERIAL ROOF ESTIMATION SYSTEMS AND METHODS 有权
标题翻译：航空屋顶估计系统和方法
公开(公告)号：US20120170797A1
公开(公告)日：2012-07-05
申请号：US13287954
申请日：2011-11-02
申请人： Chris Pershing , David P. Carlson
发明人： Chris Pershing , David P. Carlson
IPC分类号： G06K9/00
CPC分类号： G06T17/10 , G06F17/5004 , G06Q10/06313 , G06Q30/02 , G06Q30/0283 , G06T7/32 , G06T7/337 , G06T11/60 , G06T17/20 , G06T19/20 , G06T2200/08 , G06T2207/10032 , G06T2207/30184 , G06T2210/04 , G06T2219/004
摘要： Methods and systems for roof estimation are described. Example embodiments include a roof estimation system, which generates and provides roof estimate reports annotated with indications of the size, geometry, pitch and/or orientation of the roof sections of a building. Generating a roof estimate report may be based on one or more aerial images of a building. In some embodiments, generating a roof estimate report of a specified building roof may include generating a three-dimensional model of the roof, and generating a report that includes one or more views of the three-dimensional model, the views annotated with indications of the dimensions, area, and/or slope of sections of the roof. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：描述屋顶估计的方法和系统。示例性实施例包括屋顶估计系统，其生成并提供用建筑物的屋顶部分的尺寸，几何形状，俯仰和/或取向的指示注释的屋顶估计报告。生成屋顶估计报告可以基于建筑物的一个或多个空中图像。在一些实施例中，生成指定建筑物屋顶的屋顶估计报告可以包括生成屋顶的三维模型，以及生成包括三维模型的一个或多个视图的报告，所述视图用屋顶部分的尺寸，面积和/或坡度。提供本摘要以符合要求摘要的规则，并提交其意图是不会用于解释或限制权利要求书的范围或含义。

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