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    • 5. 发明授权
    • Medicament delivery device
    • 药物输送装置
    • US08372031B2
    • 2013-02-12
    • US12995516
    • 2009-05-26
    • Gunnar ElménSebastian Karlsson
    • Gunnar ElménSebastian Karlsson
    • A61M37/00
    • A61M5/2066A61M5/2448A61M5/284A61M2005/2073
    • The present invention relates to an injection device for manually penetrating a needle arranged to said device and automatic injecting a medicament mixture, the device being of the type comprising: a first housing part into which a multi-chamber container is arranged and a second housing part which can be displaced relative to said first housing in order to mix at least two substances arranged inside said container; a plunger rod arranged to act on said container, drive force means capable of pushing said plunger rod for acting on said container, an activation member comprising flexible locking means releasibly connected to said plunger rod for holding said plunger rod and thereby said drive force means in a pre-tensioned state, and a push button protruding from said second housing part; and a locking member being arranged around said activation member and being axially slidable in relation to said activation member between a first position wherein said locking member completely surrounds said locking means and a second position wherein said locking member partially surrounds said locking means after said locking member has been axially displaced by said first housing when said first housing has been displaced into said second housing part; and wherein said flexible locking means are arranged to be released from said plunger rod only after said locking member is moved from the first position to the second position and said push button is axially moved into the second housing part, such that the flexible locking means comes completely out of contact with the locking member.
    • 本发明涉及一种用于手动穿透布置在所述装置上的针并自动注射药物混合物的注射装置,所述装置的特征在于包括:第一壳体部分,多室容器布置在其中;第二壳体部分 其可以相对于所述第一壳体移位,以便混合布置在所述容器内的至少两种物质; 柱塞杆,其布置成作用在所述容器上,驱动力装置,其能够推动所述柱塞杆作用在所述容器上;致动构件,包括可释放地连接到所述柱塞杆的柔性锁定装置,用于保持所述柱塞杆,从而所述驱动力装置 预张紧状态和从所述第二壳体部分突出的按钮; 以及锁定构件,围绕所述致动构件设置并且在第一位置和第二位置之间可相对于所述致动构件轴向滑动,其中所述锁定构件完全包围所述锁定装置和第二位置,其中所述锁定构件在所述锁定构件之后部分地围绕所述锁定装置 当所述第一壳体已经移位到所述第二壳体部分中时,所述第一壳体已经被所述第一壳体轴向移位; 并且其中所述柔性锁定装置仅在所述锁定构件从所述第一位置移动到所述第二位置之后被布置成从所述柱塞杆释放,并且所述按钮被轴向移动到所述第二壳体部分中,使得所述柔性锁定装置来 完全不与锁定构件接触。
    • 6. 发明授权
    • Medicament delivery device
    • 药物输送装置
    • US08529503B2
    • 2013-09-10
    • US13265221
    • 2010-04-19
    • Gunnar ElménSebastian Karlsson
    • Gunnar ElménSebastian Karlsson
    • A61M37/00
    • A61M5/2459A61M5/3129A61M5/31511A61M5/482A61M5/484A61M5/488
    • The present invention relates to a medicament delivery device comprising a generally elongated housing comprising a proximal part (10) and a distal part (12); a medicament cartridge (18) comprising a proximal opening closed by a septum (30), an axially movable distal stopper (26), and a first enclosure (20) wherein a liquid and a gaseous fluid are enclosed; a medicament delivery member (36) attachable to said proximal part (10) and having a non-delivery end (34); a medicament cartridge holder (16) wherein the medicament cartridge is coaxially arranged, said cartridge holder being arranged coaxially movable inside said proximal part and comprising holding means (38, 40) capable of holding said medicament cartridge holder (16) in a non-activated position in which said cartridge holder is releasebly engaged to said proximal part and in which a predetermined distance is present between the septum and the non delivery end; a manual pressure mechanism arranged to be moved from a non-pressure position to a pressure position wherein a pressure is build-up inside said cartridge; and an activation mechanism arranged to interact with said holding means only when said manual pressure mechanism is in the pressure position for disengaging said cartridge holder from said non-activated position to an activated position in which said cartridge holder is axially displaced said predetermined distance whereby said septum is penetrated by the non-delivery end and the liquid is expelled due to the pressure built inside the enclosure.
    • 本发明涉及一种药物输送装置,其包括大致细长的壳体,其包括近端部分(10)和远端部分(12); 包括由隔膜(30)闭合的近侧开口的药剂盒(18),可轴向移动的远端止动器(26)和第一外壳(20),其中封闭液体和气体流体; 可附接到所述近端部分(10)并且具有非输送端(34)的药物输送构件(36)。 药剂盒保持器(16),其中所述药剂盒同轴地布置,所述药筒保持器在所述近端部分内同轴地设置,并且包括能够将所述药剂盒保持器(16)保持在未激活状态的保持装置(38,40) 其中所述盒保持器与所述近端部分释放地接合并且在隔膜和非输送端之间存在预定距离; 手动压力机构,被布置成从非压力位置移动到压力位置,其中压力在所述盒内积聚; 以及激活机构,其布置成仅当所述手动压力机构处于用于将所述盒保持器与所述未启动位置分离的压力位置到所述盒保持器在所述预定距离轴向移动的启动位置时与所述保持装置相互作用,由此所述启动机构 隔膜被非输送端穿透,并且液体由于封装内部的压力而被排出。
    • 7. 发明申请
    • Medicament Delivery Device
    • 药物输送装置
    • US20110077589A1
    • 2011-03-31
    • US12996232
    • 2009-05-29
    • Sebastian KarlssonGunnar Elmén
    • Sebastian KarlssonGunnar Elmén
    • A61M5/31A61M5/315
    • A61M5/20A61M5/2033A61M5/24A61M5/2448A61M5/3129A61M5/31511A61M5/422A61M2005/2407A61M2005/2451A61M2005/2488A61M2205/581
    • The present invention relates to medicament delivery device comprising a generally tubular distal housing part (19); a generally tubular medicament container holder (16); a medicament container (18); a plunger rod (32); resilient force; an actuation means (34) comprising flexible locking means and an activation button; a release means (40); and a resilient means (60) characterised in that said plunger rod comprises a number of stop engagements (38) arranged on its outer circumferential surface and arranged to co-act with corresponding stop engagements (37) on the flexible locking means, such that when said activation button is proximally depressed said stop engagement (37) on said flexible locking means come out of contact from one stop engagement (38) of the plunger rod; and such that when said activation button (48) is released, said resilient means (60) forces the activation button and thereby the flexible locking means to move distally such that said stop engagements (37) on said flexible locking means come into contact with another stop engagement (38) of the plunger rod.
    • 本发明涉及药物输送装置,其包括大致管状的远端壳体部分(19); 一个大致管状的药物容器支架(16); 药物容器(18); 柱塞杆(32); 弹性力 致动装置(34),包括柔性锁定装置和激活按钮; 释放装置(40); 和弹性装置(60),其特征在于,所述柱塞杆包括多个止动接合件(38),其布置在其外圆周表面上并且布置成与所述柔性锁定装置上的对应止动接合部(37)共同作用, 所述激活按钮在近侧压下,所述柔性锁定装置上的所述止动接合(37)从所述柱塞杆的一个止动接合(38)脱离接触; 并且使得当所述启动按钮(48)被释放时,所述弹性装置(60)迫使所述启动按钮,从而所述柔性锁定装置向远侧移动,使得所述柔性锁定装置上的所述停止接合件(37)与另一个接触 停止接合(38)的柱塞杆。
    • 9. 发明申请
    • Medicament Delivery Device
    • 药物输送装置
    • US20110087163A1
    • 2011-04-14
    • US12995516
    • 2009-05-26
    • Gunnar ElménSebastian Karlsson
    • Gunnar ElménSebastian Karlsson
    • A61M5/31
    • A61M5/2066A61M5/2448A61M5/284A61M2005/2073
    • The present invention relates to an injection device for manually penetrating a needle arranged to said device and automatic injecting a medicament mixture, the device being of the type comprising: a first housing part into which a multi-chamber container is arranged and a second housing part which can be displaced relative to said first housing in order to mix at least two substances arranged inside said container; a plunger rod arranged to act on said container, drive force means capable of pushing said plunger rod for acting on said container, an activation member comprising flexible locking means releasibly connected to said plunger rod for holding said plunger rod and thereby said drive force means in a pre-tensioned state, and a push button protruding from said second housing part; and a locking member being arranged around said activation member and being axially slidable in relation to said activation member between a first position wherein said locking member completely surrounds said locking means and a second position wherein said locking member partially surrounds said locking means after said locking member has been axially displaced by said first housing when said first housing has been displaced into said second housing part; and wherein said flexible locking means are arranged to be released from said plunger rod only after said locking member is moved from the first position to the second position and said push button is axially moved into the second housing part, such that the flexible locking means comes completely out of contact with the locking member.
    • 本发明涉及一种用于手动穿透布置在所述装置上的针并自动注射药物混合物的注射装置,所述装置的特征在于包括:第一壳体部分,多室容器布置在其中;第二壳体部分 其可以相对于所述第一壳体移位,以便混合布置在所述容器内的至少两种物质; 柱塞杆,其布置成作用在所述容器上,驱动力装置,其能够推动所述柱塞杆作用在所述容器上;致动构件,包括可释放地连接到所述柱塞杆的柔性锁定装置,用于保持所述柱塞杆,从而所述驱动力装置 预张紧状态和从所述第二壳体部分突出的按钮; 以及锁定构件,围绕所述致动构件设置并且在第一位置和第二位置之间可相对于所述致动构件轴向滑动,其中所述锁定构件完全包围所述锁定装置和第二位置,其中所述锁定构件在所述锁定构件之后部分地围绕所述锁定装置 当所述第一壳体已经移位到所述第二壳体部分中时,所述第一壳体已经被所述第一壳体轴向移位; 并且其中所述柔性锁定装置仅在所述锁定构件从所述第一位置移动到所述第二位置之后被布置成从所述柱塞杆释放,并且所述按钮被轴向移动到所述第二壳体部分中,使得所述柔性锁定装置来 完全不与锁定构件接触。