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1. 发明授权

US06204431B1 Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk 失效
标题翻译：表达异源糖基转移酶DNA序列的转基因非人哺乳动物在其牛奶中产生寡糖和糖蛋白
公开(公告)号：US06204431B1
公开(公告)日：2001-03-20
申请号：US08925834
申请日：1997-09-05
申请人： Pedro A. Prieto , John J. Kopchick , Richard D. Cummings , James M. Pierce , David F. Smith , Kelley W. Moremen
发明人： Pedro A. Prieto , John J. Kopchick , Richard D. Cummings , James M. Pierce , David F. Smith , Kelley W. Moremen
IPC分类号： A01K67027
CPC分类号： C12N15/8509 , A01K67/0275 , A01K2217/05 , A01K2227/10 , A01K2227/105 , A01K2227/107 , A01K2267/01 , A23C9/20 , C12N9/1048 , C12N9/1051 , C12N9/1077
摘要： The subject invention relates to methods of producing non-human transgenic mammals which produce various oligosaccharides and glycoconjugates in their milk. Additionally, the subject invention relates to the mammals themselves, the milk which they produce, compositions comprising the milk, fractions of the milk, and the purified oligosaccharides, as well as glyconjugates, present in the milk.
摘要翻译：本发明涉及生产在其乳中产生各种寡糖和糖缀合物的非人转基因哺乳动物的方法。此外，本发明涉及哺乳动物本身，它们产生的乳，包含乳的组分，乳的部分和纯化的寡糖以及存在于牛奶中的糖缀合物。

2. 发明授权

US09772337B2 Compositions and methods for functional gylcomics 有权
公开(公告)号：US09772337B2
公开(公告)日：2017-09-26
申请号：US13885916
申请日：2011-11-22
申请人： Richard D. Cummings , David F. Smith , Xuezheng Song
发明人： Richard D. Cummings , David F. Smith , Xuezheng Song
IPC分类号： G01N33/92 , C07C237/34 , C07H15/18 , C40B40/12
CPC分类号： G01N33/92 , C07B2200/11 , C07C237/34 , C07H15/18 , C40B40/12
摘要： The disclosure relates to labeling glycans and glycosphingolipids from undefined mixtures with chemical moieties that emit light when exposed to electromagnetic radiation and uses of these labeled glycans and glycosphingolipids in microarrays for research and diagnostic purposes. In certain embodiments, the disclosure relates to derivatizing glycosphingolipids with a marker.

3. 发明申请

US20130331280A1 COMPOSITIONS AND METHODS FOR FUNCTIONAL GYLCOMICS 审中-公开
标题翻译：功能性GYLCOMICS的组成和方法
公开(公告)号：US20130331280A1
公开(公告)日：2013-12-12
申请号：US13885916
申请日：2011-11-22
申请人： Richard D. Cummings , David F. Smith , Xuezheng Song
发明人： Richard D. Cummings , David F. Smith , Xuezheng Song
IPC分类号： G01N33/92
CPC分类号： G01N33/92 , C07B2200/11 , C07C237/34 , C07H15/18 , C40B40/12
摘要： The disclosure relates to labeling glycans and glycosphingolipids from undefined mixtures with chemical moieties that emit light when exposed to electromagnetic radiation and uses of these labeled glycans and glycosphingolipids in microarrays for research and diagnostic purposes. In certain embodiments, the disclosure relates to derivatizing glycosphingolipids with a marker.
摘要翻译：本公开涉及从暴露于电磁辐射时发出光的化学部分的未定义混合物中标记聚糖和糖鞘糖，并将这些标记的聚糖和糖鞘糖在微阵列中用于研究和诊断目的。在某些实施方案中，本公开涉及用具有标记物衍生鞘糖脂。

4. 发明授权

US08498658B2 Techniques and systems for providing data over power in communications based on time reversal 有权
标题翻译：基于时间反转提供通信中的电力数据的技术和系统
公开(公告)号：US08498658B2
公开(公告)日：2013-07-30
申请号：US13142250
申请日：2010-09-03
申请人： David F. Smith , Anis Husain
发明人： David F. Smith , Anis Husain
IPC分类号： H04B7/00 , H04B15/00
CPC分类号： H04L25/03834 , H04L25/0212 , H04L25/03133 , H04L25/03343
摘要： Techniques, apparatuses and systems for providing communications based on time reversal of a channel impulse response of a pulse in a transmission channel between a transmitter and a receiver to enhance reception and detection of a pulse at the receiver against various effects that can adversely affect and complicate the reception and detection of the pulse at the receiver.
摘要翻译：用于基于在发射机和接收机之间的传输信道中的脉冲的信道脉冲响应的时间反转来提供通信的技术，装置和系统，以增强在接收机处的接收和检测脉冲，以防止可能不利地影响和复杂的各种效应在接收器处接收和检测脉冲。

5. 发明申请

US20100107522A1 SYNTHETIC SUPPORT BASE FOR MODULAR FLOORING 审中-公开
标题翻译：用于模块化地板的合成支撑基座
公开(公告)号：US20100107522A1
公开(公告)日：2010-05-06
申请号：US12688222
申请日：2010-01-15
申请人： Andrew Gettig , Ronald A. Yokubison , David F. Smith , Charlie M. Graves , Troy D. Mohr , Thayne B. Haney , Joseph M. Ure
发明人： Andrew Gettig , Ronald A. Yokubison , David F. Smith , Charlie M. Graves , Troy D. Mohr , Thayne B. Haney , Joseph M. Ure
IPC分类号： E04F15/22 , E04F15/10 , E04B5/43
CPC分类号： E01C13/045
摘要： A flooring system configured to accommodate sports play and other activities, wherein the flooring system comprises a support base having a synthetic component, such as a synthetic support structure, wherein the support base is configured to provide a support surface for receiving and supporting a flooring configuration. The support base may further comprise a filler material operable with the synthetic support component, wherein the synthetic support component is integrated into the filler material.
摘要翻译：一种被配置为适应运动游戏和其他活动的地板系统，其中地板系统包括具有诸如合成支撑结构的合成部件的支撑基座，其中支撑基座构造成提供用于接收和支撑地板构造的支撑表面。支撑基座还可以包括可与合成支撑部件一起操作的填充材料，其中合成支撑部件被整合到填充材料中。

6. 发明授权

US5737348A Light source monitor with compensated tracking ratio 失效
标题翻译：补偿跟踪比率的光源监视器
公开(公告)号：US5737348A
公开(公告)日：1998-04-07
申请号：US739471
申请日：1996-10-28
申请人： David F. Smith
发明人： David F. Smith
IPC分类号： H01S5/022 , H01S5/0683 , H01S5/183 , H01S3/10
CPC分类号： H01S5/02296 , H01S5/0683 , H01S5/183
摘要： A laser monitor is provided with a light sensitive component disposed near the laser and spaced apart from two windows that are generally parallel to each other. The two windows are located at positions which provide compensating reflective light beams whose power reflected back onto the light sensitive component combine to provide a relatively constant sum over a finite range of magnitudes of divergences of the laser beam. The nearest window to the light sensitive component reflects a light beam with a generally circular illuminated region having a smaller diameter than the diameter of the light sensitive component. The farther window reflects a light beam onto the light sensitive component with a diameter that is larger than the light sensitive component. As the numerical aperture of the laser increases, both illuminated circles increase in diameter and the increase in one reflected beam compensates the decrease in the other reflected beam so that the sum of the two powers falling on the detector is generally constant over the preselected range of numerical apertures. This provides a relatively constant tracking ratio that enables the light sensitive component to serve as a reliable monitor of the emitted power from the laser, which can be a VCSEL.
摘要翻译：激光监视器设置有设置在激光附近的光敏部件，并且与两个通常彼此平行的窗口间隔开。两个窗口位于提供补偿反射光束的位置，反射光束反射回光敏元件上，其功率在激光束的发散幅度的有限范围内提供相对恒定的和。对光敏部件的最近窗口反射具有直径小于光敏部件直径的大致圆形照明区域的光束。更远的窗口将光束反射到光敏部件上，其直径大于光敏部件。随着激光器的数值孔径的增加，两个照明圆的直径都增加，一个反射光束的增加补偿了另一个反射光束的减小，使得落在检测器上的两个光功率的和通常在预选的范围内是恒定的数值孔径。这提供了相对恒定的跟踪比，其使得光敏部件能够用作来自激光器（其可以是VCSEL）的发射功率的可靠监视器。

7. 发明授权

US4781428A Devices and methods for selectively tapping optical energy from an optical fibre 失效
标题翻译：用于选择性地从光纤中分离光能的装置和方法
公开(公告)号：US4781428A
公开(公告)日：1988-11-01
申请号：US748296
申请日：1985-06-24
申请人： Richard E. Epworth , Stephen Wright , Roger J. Brambley , David F. Smith
发明人： Richard E. Epworth , Stephen Wright , Roger J. Brambley , David F. Smith
IPC分类号： G02B6/293 , G02B6/14 , G02B6/287 , G02B6/34 , G02B26/00 , H04B10/158
CPC分类号： G02B26/002 , G02B6/02071 , G02B6/14 , G02B6/29322 , Y10S359/90
摘要： Optical energy at a predetermined frequency or narrow band of frequencies is tapped from an optical fibre by causing spatially periodic deformation of the fibre such as to produce coupling of optical energy between modes of the fibre, for example between the core and cladding of a single mode fibre, at the predetermined frequency and removing the optical energy at the predetermined frequency, for example by means of a cladding mode tap for a single mode fibre. If the deformation means includes a mechanical grating then tuning of the coupling frequency can be achieved by changing the relative orientation (O) of the fibre and the grating.
摘要翻译：通过引起光纤的空间周期性变形，例如在光纤的模式之间产生光能的耦合，例如在单模的芯和包层之间，从光纤中抽出预定频率或窄频带的光能光纤，以预定的频率，并且以预定频率去除光能，例如通过用于单模光纤的包层模式抽头。如果变形装置包括机械光栅，则可以通过改变光纤和光栅的相对取向（O）来实现耦合频率的调谐。

8. 发明授权

US4166744A Adhesive cements especially adapted to surgical use 失效
标题翻译：胶粘剂特别适用于外科用途
公开(公告)号：US4166744A
公开(公告)日：1979-09-04
申请号：US801609
申请日：1977-05-31
申请人： David F. Smith
发明人： David F. Smith
IPC分类号： A61K6/083 , C09K3/00
CPC分类号： A61K6/0038 , A61K6/0835 , Y10S528/92
摘要： Zinc oxide and weak unpolymerized and polymerized acids when mixed in the presence of water form adhesives that quickly set to firm, hard cements that are especially useful in dentistry and surgery. Mixtures of ZnO and solid such acids can be provided but must be exceptionally dry and be so maintained in order to have satisfactory shelf life.
摘要翻译：在水存在下混合时，氧化锌和弱的未聚合和聚合的酸形成粘合剂，其快速地固化成在牙科和手术中特别有用的坚硬的硬水泥。可以提供ZnO和固体这样的酸的混合物，但是必须特别干燥并保持其以保持良好的保质期。

9. 发明申请

US20110229145A1 OPTICAL COMMUNICATIONS IN AMPLIFIED RECIPROCAL NETWORKS 有权
标题翻译：放大的互联网络中的光通信
公开(公告)号：US20110229145A1
公开(公告)日：2011-09-22
申请号：US13119902
申请日：2009-09-29
申请人： David F. Smith , Anis Husan
发明人： David F. Smith , Anis Husan
IPC分类号： H04B10/17
CPC分类号： H04B10/2935
摘要： Techniques, apparatus and systems to provide carrier signal transmission in reciprocal transmission architecture networks for optical communications.
摘要翻译：技术，装置和系统，用于在用于光通信的相互传输架构网络中提供载波信号传输。

10. 发明申请

US20100310251A1 Optical Transmission Systems, Devices, and Methods 有权
标题翻译：光传输系统，设备和方法
公开(公告)号：US20100310251A1
公开(公告)日：2010-12-09
申请号：US12823207
申请日：2010-06-25
申请人： David F. Smith
发明人： David F. Smith
IPC分类号： G02F1/00
CPC分类号： H04J14/0227 , H04J14/02 , H04J14/0204 , H04J14/0209 , H04J14/0212 , H04J14/0213 , H04J14/0217 , H04J14/0228 , H04J14/0241 , H04J14/0257 , H04J14/0263 , H04J14/0283 , H04J14/0284 , H04J14/0286 , H04J14/0287 , H04J14/029 , H04J14/0294
摘要： An optical system with a first and second network tiers. The first network tier includes a plurality of major nodes optically interconnected by at least one transmission path. The second network tier includes a plurality of minor nodes disposed along the transmission path and the minor nodes are connected to at least one of the major nodes. The minor node is configured to transmit all traffic to an adjacent major node, and the major nodes are configured to transmit to and receive information from other major nodes and minor nodes on transmission paths connected to the major node.
摘要翻译：具有第一和第二网络层的光学系统。第一网络层包括通过至少一个传输路径光学互连的多个主要节点。第二网络层包括沿着传输路径布置的多个次要节点，并且次要节点连接到至少一个主要节点。次要节点被配置为将所有业务传输到相邻的主节点，并且主节点被配置为向连接到主节点的传输路径上的其他主节点和次节点传送信息并从其接收信息。

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