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1. 发明授权

US07283652B2 Method and system for measuring disease relevant tissue changes 有权
标题翻译：测量疾病相关组织变化的方法和系统
公开(公告)号：US07283652B2
公开(公告)日：2007-10-16
申请号：US10065894
申请日：2002-11-27
申请人： Paulo Ricardo Mendonca , Matthew William Turek , James Vradenburg Miller , Robert August Kaucic , Peter Henry Tu , Tony Chishao Pan
发明人： Paulo Ricardo Mendonca , Matthew William Turek , James Vradenburg Miller , Robert August Kaucic , Peter Henry Tu , Tony Chishao Pan
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T2207/30061
摘要： A method and system for measuring disease relevant tissue changes for use in quantifying, diagnosing and predicting a given disease are provided. The method comprises applying at least one segmenting process to the image data to generate a plurality of segmented regions of interest, extracting features relevant for a given disease from the segmented regions to generate extracted features, and mathematically modeling the features for use in one of diagnosing, quantifying and predicting changes indicative of the given disease. The system comprises an imaging device for acquiring the image data and an image process configured to segment, extract and mathematically model disease relevant features.
摘要翻译：提供了用于量化，诊断和预测给定疾病的用于测量疾病相关组织变化的方法和系统。该方法包括对图像数据应用至少一个分割过程以产生多个感兴趣的分割区域，从分割区域提取与给定疾病相关的特征以产生提取的特征，以及数学模拟特征以用于诊断之一，量化和预测指示给定疾病的变化。该系统包括用于获取图像数据的成像装置和被配置为分割，提取和数学地模拟疾病相关特征的图像处理。

2. 发明申请

US20050105788A1 Methods and apparatus for processing image data to aid in detecting disease 有权
标题翻译：用于处理图像数据以辅助检测疾病的方法和装置
公开(公告)号：US20050105788A1
公开(公告)日：2005-05-19
申请号：US10717861
申请日：2003-11-19
申请人： Matthew William Turek , Joseph Leagrand Mundy , Tony Chi-Shao Pan , Peter Henry Tu , James Vradenburg Miller , Robert August Kaucic , Xiaoye Wu , Paulo Ricardo dos Santos Mendonca
发明人： Matthew William Turek , Joseph Leagrand Mundy , Tony Chi-Shao Pan , Peter Henry Tu , James Vradenburg Miller , Robert August Kaucic , Xiaoye Wu , Paulo Ricardo dos Santos Mendonca
IPC分类号： A61B6/03 , A61B5/08 , A61B10/00 , A61B19/00 , G06F17/00 , G06K9/00 , G06T7/00
CPC分类号： G06T7/0012 , G06F19/00 , G06F19/321 , G06T2207/30061 , G16H50/20
摘要： A method for detecting, quantifying, staging, reporting, and/or tracking of a disease includes providing analysis software configured to detect, quantify, stage, report, and/or track a disease utilizing images of a patient. The analysis software is executable on a personal computer of a patient. Patients are then imaged utilizing a medical imaging apparatus and medical images of the patient produced by the imaging apparatus are downloaded to the personal computer of the patient. The imaging and downloading are repeated a plurality of times at intervals selected to provide the analysis software with sufficient images to detect, quantify, stage, report, and/or track the disease in the patient.
摘要翻译：用于检测，量化，分期，报告和/或跟踪疾病的方法包括提供被配置为利用患者的图像来检测，量化，分段，报告和/或跟踪疾病的分析软件。分析软件可在患者的个人计算机上执行。然后使用医学成像装置对患者进行成像，并且将由成像装置产生的患者的医学图像下载到患者的个人计算机。以选择的间隔重复成像和下载多次，以使分析软件具有足够的图像以检测，量化，分级，报告和/或跟踪患者的疾病。

3. 发明授权

US07346203B2 Methods and apparatus for processing image data to aid in detecting disease 有权
标题翻译：用于处理图像数据以辅助检测疾病的方法和装置
公开(公告)号：US07346203B2
公开(公告)日：2008-03-18
申请号：US10717861
申请日：2003-11-19
申请人： Matthew William Turek , Joseph Leagrand Mundy , Tony Chi-shao Pan , Peter Henry Tu , James Vradenburg Miller , Robert August Kaucic, Jr. , Xiaoye Wu , Paulo Ricardo dos Santos Mendonca
发明人： Matthew William Turek , Joseph Leagrand Mundy , Tony Chi-shao Pan , Peter Henry Tu , James Vradenburg Miller , Robert August Kaucic, Jr. , Xiaoye Wu , Paulo Ricardo dos Santos Mendonca
IPC分类号： G06K9/00 , G06K9/34 , A61B5/00 , A61B5/05
CPC分类号： G06T7/0012 , G06F19/00 , G06F19/321 , G06T2207/30061 , G16H50/20
摘要： A method for detecting, quantifying, staging, reporting, and/or tracking of a disease includes providing analysis software configured to detect, quantify, stage, report, and/or track a disease utilizing images of a patient. The analysis software is executable on a personal computer of a patient. Patients are then imaged utilizing a medical imaging apparatus and medical images of the patient produced by the imaging apparatus are downloaded to the personal computer of the patient. The imaging and downloading are repeated a plurality of times at intervals selected to provide the analysis software with sufficient images to detect, quantify, stage, report, and/or track the disease in the patient.
摘要翻译：用于检测，量化，分期，报告和/或跟踪疾病的方法包括提供被配置为利用患者的图像来检测，量化，分段，报告和/或跟踪疾病的分析软件。分析软件可在患者的个人计算机上执行。然后使用医学成像装置对患者进行成像，并且将由成像装置产生的患者的医学图像下载到患者的个人计算机。以选择的间隔重复成像和下载多次，以使分析软件具有足够的图像以检测，量化，分级，报告和/或跟踪患者的疾病。

4. 发明授权

US07116810B2 Method and system for airway measurement 有权
标题翻译：气道测量方法和系统
公开(公告)号：US07116810B2
公开(公告)日：2006-10-03
申请号：US10065878
申请日：2002-11-27
申请人： James Vradenburg Miller , Matthew William Turek , Joseph Leagrand Mundy , Peter Henry Tu
发明人： James Vradenburg Miller , Matthew William Turek , Joseph Leagrand Mundy , Peter Henry Tu
IPC分类号： G06K9/00 , A61B5/08
CPC分类号： G06T7/62
摘要： A method for measuring tubular anatomical structures, for example lung airways, comprises isolating by at least one segmentation process a given tubular anatomical structure of interest and measuring at least one attribute of the structure of interest. A system for measuring lung airways using acquired image data is provided. The system comprises an imaging device for acquiring the image data and an image processing device coupled to the imaging device. The imaging processing device is configured for isolating by at least one segmentation process a given airway of interest, fitting an inner ellipse to an inner boundary of the given airway and an outer ellipse to an outer boundary of the airway structure using statistical techniques at a given point in the airway, and further configured for generating measurements of the given airway using the inner and outer ellipses.
摘要翻译：用于测量管状解剖结构（例如肺气道）的方法包括通过至少一个分割过程分离给定的感兴趣的管状解剖结构并测量感兴趣结构的至少一个属性。提供了一种使用获取的图像数据测量肺气道的系统。该系统包括用于获取图像数据的成像装置和耦合到成像装置的图像处理装置。成像处理装置被配置为通过至少一个分割过程将感兴趣的给定气道进行隔离，使用给定的气道结构的统计技术将内部椭圆拟合到给定气道的内边界和外部椭圆到气道结构的外边界并且还被配置为使用内部和外部椭圆产生给定气道的测量。

5. 发明授权

US07058210B2 Method and system for lung disease detection 失效
公开(公告)号：US07058210B2
公开(公告)日：2006-06-06
申请号：US09683111
申请日：2001-11-20
申请人： Joseph Leagrand Mundy , Colin Craig McCulloch , Ricardo Scott Avila , Shannon Lee Hastings , Robert August Kaucic, Jr. , William Edward Lorensen , Matthew William Turek
发明人： Joseph Leagrand Mundy , Colin Craig McCulloch , Ricardo Scott Avila , Shannon Lee Hastings , Robert August Kaucic, Jr. , William Edward Lorensen , Matthew William Turek
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , A61B6/00 , G06T2207/30061
摘要： A method for processing medical images for use in the detection and diagnosis of disease comprises classifying regions of interest within the medical images based on a hierarchy of anatomical models and signal models of signal information of an image acquisition device used to acquire the medical images. The anatomical models are derived to be representative of anatomical information indicative of a given disease. A computer-aided system for use in the diagnosis and detection of disease comprises an image acquisition device for acquiring a plurality of image data sets and a processor adapted to process the image data sets. The processor is adapted to classify selected tissue types within the image data sets based on a hierarchy of signal and anatomical models and the processor is further adapted to differentiate anatomical context of the classified tissue types for use in the diagnosis and detection of disease.

6. 发明授权

US07433086B2 Edge detection and correcting system and method 有权
标题翻译：边缘检测和校正系统及方法
公开(公告)号：US07433086B2
公开(公告)日：2008-10-07
申请号：US10951301
申请日：2004-09-27
申请人： James Vradenburg Miller , Paulo Ricardo Dos Santos Mendonca , Matthew William Turek , Dirk Ryan Padfield
发明人： James Vradenburg Miller , Paulo Ricardo Dos Santos Mendonca , Matthew William Turek , Dirk Ryan Padfield
IPC分类号： H04N1/40
CPC分类号： G06T5/003 , G06T7/13 , G06T2207/30004
摘要： An imaging system for correcting a bias in the location edges in an image is provided. The imaging system comprises an image processor configured to detect edges in an image of a given substructure, characterize a blurring factor in the image and correct a bias in the detected edges in the of a given substructure using the blurring factor.
摘要翻译：提供了用于校正图像中的位置边缘中的偏置的成像系统。成像系统包括被配置为检测给定子结构的图像中的边缘的图像处理器，表征图像中的模糊因子，并使用模糊因子校正给定子结构中的检测到的边缘中的偏差。

7. 发明授权

US06754376B1 Method for automatic segmentation of medical images 失效
标题翻译：医学图像自动分割方法
公开(公告)号：US06754376B1
公开(公告)日：2004-06-22
申请号：US09721195
申请日：2000-11-22
申请人： Matthew William Turek , Jerome Francois Knoplioch , Alexis Vapillon
发明人： Matthew William Turek , Jerome Francois Knoplioch , Alexis Vapillon
IPC分类号： G06K900
CPC分类号： G06T7/0012 , G06T7/11 , G06T7/187 , G06T2207/10081 , G06T2207/10088 , G06T2207/20101
摘要： An method for automatically extracting a three-dimensional sub-structure, for example a coronary vessel tree, from a plurality of slice images comprises the steps of depositing a seed point within a selected region of interest and segmenting the plurality of slice images responsive to the deposition of the seed point. The segmentation is performed in accordance with a plurality of predetermined classification values to extract the three-dimensional sub-structure. A method for automatically segmenting comprises the steps of receiving a deposited seed point, extracting a plurality of desired regions within the sub-structure and generating a segmented sub-structure from the extracted desired regions.
摘要翻译：一种用于从多个切片图像自动提取三维子结构（例如冠状血管树）的方法包括以下步骤：在所选择的感兴趣区域内沉积种子点，并响应于所述多个切片图像分割多个切片图像沉淀种子点。根据多个预定分类值执行分割以提取三维子结构。一种用于自动分割的方法包括以下步骤：接收沉积的种子点，在子结构内提取多个期望的区域，并从所提取的期望区域产生分割的子结构。

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