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1. 发明授权

US08716312B2 Inhibitors of diacylglycerol acyltransferase 失效
标题翻译：二酰基甘油酰基转移酶抑制剂
公开(公告)号：US08716312B2
公开(公告)日：2014-05-06
申请号：US13129843
申请日：2009-11-17
申请人： Pauline C. Ting , Robert Aslanian , Mary Ann Caplen , Jianhua Cao , Tin-Yau Chan , David Kim , Hyunjin Kim , Jae-Hun Kim , Rongze Kuang , Joe F. Lee , John Schwerdt , Heping Wu , Nicolas Zorn
发明人： Pauline C. Ting , Robert Aslanian , Mary Ann Caplen , Jianhua Cao , Tin-Yau Chan , David Kim , Hyunjin Kim , Jae-Hun Kim , Rongze Kuang , Joe F. Lee , John Schwerdt , Heping Wu , Nicolas Zorn
IPC分类号： A61P3/00 , A61P9/00 , A61K31/445 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
CPC分类号： C07D413/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/10 , C07D487/04
摘要： The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below:
摘要翻译：本发明涉及作为二酰基甘油酰基转移酶（“DGAT”）抑制剂的新型杂环化合物，包含杂环化合物的药物组合物和用于治疗或预防心血管疾病，代谢障碍，肥胖症或肥胖相关障碍的化合物的用途，糖尿病，血脂异常，糖尿病并发症，葡萄糖耐量降低或空腹血糖受损。本发明的说明性化合物如下所示：

2. 发明申请

US20110224137A1 INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE 失效
标题翻译：二乙酰胆碱酯酶抑制剂
公开(公告)号：US20110224137A1
公开(公告)日：2011-09-15
申请号：US13129843
申请日：2009-11-17
申请人： Pauline C. Ting , Robert Aslanian , Mary Ann Caplen , Jianhua Cao , Tin-Yau Chan , David Kim , Hyunjin Kim , Jae-Hun Kim , Rongze Kuang , Joe F. Lee , John Schwerdt , Heping Wu , Nicolas Zorn
发明人： Pauline C. Ting , Robert Aslanian , Mary Ann Caplen , Jianhua Cao , Tin-Yau Chan , David Kim , Hyunjin Kim , Jae-Hun Kim , Rongze Kuang , Joe F. Lee , John Schwerdt , Heping Wu , Nicolas Zorn
IPC分类号： A61K38/28 , C07D409/14 , C07D243/08 , C07D401/14 , C07D221/00 , C07D211/06 , A61K31/497 , A61K31/551 , A61K31/4545 , A61K31/438 , A61K31/454 , A61P3/04 , A61P3/10
CPC分类号： C07D413/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/10 , C07D487/04
摘要： The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below: formula (I).
摘要翻译：本发明涉及作为二酰基甘油酰基转移酶（“DGAT”）抑制剂的新型杂环化合物，包含杂环化合物的药物组合物和用于治疗或预防心血管疾病，代谢障碍，肥胖症或肥胖相关障碍的化合物的用途，糖尿病，血脂异常，糖尿病并发症，葡萄糖耐量降低或空腹血糖受损。本发明的说明性化合物如下所示：式（I）。

3. 发明申请

US20110224136A1 INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE 审中-公开
标题翻译：二乙酰胆碱酯酶抑制剂
公开(公告)号：US20110224136A1
公开(公告)日：2011-09-15
申请号：US13129830
申请日：2009-11-17
申请人： Pauline C. Ting , Robert Aslanian , Mary Ann Caplen , Jianhua Cao , David Kim , Hyunjin Kim , Rongze Kuang , Joe F. Lee , John Schwerdt , Heping Wu , Gang Zhou , Nicolas Zorn
发明人： Pauline C. Ting , Robert Aslanian , Mary Ann Caplen , Jianhua Cao , David Kim , Hyunjin Kim , Rongze Kuang , Joe F. Lee , John Schwerdt , Heping Wu , Gang Zhou , Nicolas Zorn
IPC分类号： A61K38/28 , C07D409/14 , C07D413/14 , C07D401/14 , C07D211/32 , A61K31/4965 , A61K31/497 , A61K31/5377 , A61K31/445 , A61K31/454 , A61K31/4545 , A61P3/04 , A61P3/10
CPC分类号： C07D413/14 , C07D401/12 , C07D401/14 , C07D413/04 , C07D413/12 , C07D417/12 , C07D417/14
摘要： The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below.
摘要翻译：本发明涉及作为二酰基甘油酰基转移酶（“DGAT”）抑制剂的新型杂环化合物，包含杂环化合物的药物组合物和用于治疗或预防心血管疾病，代谢障碍，肥胖症或肥胖相关障碍的化合物的用途，糖尿病，血脂异常，糖尿病并发症，葡萄糖耐量降低或空腹血糖受损。本发明的说明性化合物如下所示。

4. 发明授权

US08926635B2 Methods and devices for occlusion of an atrial appendage 有权
标题翻译：用于闭塞心房的方法和装置
公开(公告)号：US08926635B2
公开(公告)日：2015-01-06
申请号：US12572846
申请日：2009-10-02
申请人： David E. Francischelli , Roderick E. Briscoe , Leonard H. Leuer , Daniel C. Haeg , Tom P. Daigle , David Kim , Mark T. Stewart , Andrew L. Olson , Patrick J. Cloutier , Christopher W. Smith , Michael J. Hobday , Tessy Kanayinkal , Douglas H. Gubbin , Paul T. Rothstein , Joseph E. Cardinal , Jessica L. Foley , Christopher J. Plott
发明人： David E. Francischelli , Roderick E. Briscoe , Leonard H. Leuer , Daniel C. Haeg , Tom P. Daigle , David Kim , Mark T. Stewart , Andrew L. Olson , Patrick J. Cloutier , Christopher W. Smith , Michael J. Hobday , Tessy Kanayinkal , Douglas H. Gubbin , Paul T. Rothstein , Joseph E. Cardinal , Jessica L. Foley , Christopher J. Plott
IPC分类号： A61B17/12 , A61B17/128 , A61B17/00
CPC分类号： A61B17/12 , A61B17/12009 , A61B17/1285 , A61B2017/00243 , A61B2017/12018
摘要： A novel occluder application and clip device for treatment of embolic stroke caused by atrial fibrillation uses multiple sutures in a non directional handle to affix the occlusion device to the applicator and manipulate the occluder from an open and receiving position to a closed and occluding position. The occluder is retained in place by a clamping means related to locks retainers, resilient material or otherwise. An actuator mechanism is used to manipulate the occluder to a locked or occluding position. The applicator with the occluder attached has a low profile and remote manipulations to allow the occluder to be delivered to the clamping location within a patient through a small incision or delivery port such as a trocar cannula or the like.
摘要翻译：用于治疗由心房颤动引起的栓塞性中风的新型闭塞器应用和夹持装置在非方向性手柄中使用多个缝线以将闭塞装置固定到施用器上，并将闭塞器从打开和接收位置操纵到闭合和闭塞位置。封闭器通过与锁定件，弹性材料或其他方式相关的夹紧装置保持在适当的位置。致动器机构用于将闭塞器操纵到锁定或闭塞位置。具有闭塞器的施用器具有低轮廓和远程操作，以允许阻塞器通过诸如套管针插管等的小切口或输送口输送到患者体内的夹紧位置。

5. 发明授权

US08663245B2 Device for occlusion of a left atrial appendage 有权
标题翻译：用于闭塞左心耳的装置
公开(公告)号：US08663245B2
公开(公告)日：2014-03-04
申请号：US11788261
申请日：2007-04-19
申请人： David E. Francischelli , Roderick E. Briscoe , Leonard H. Leuer , Daniel C. Haeg , Tom P. Daigle , David Kim , Mark T. Stewart , Andrew L. Olson , Patrick J. Cloutier , Christopher W. Smith , Michael J. Hobday , Tessy Kanayinkal , Douglas H. Gubbin , Paul T. Rothstein , Joseph E. Cardinal , Jessica L. Foley , Christopher J. Plott
发明人： David E. Francischelli , Roderick E. Briscoe , Leonard H. Leuer , Daniel C. Haeg , Tom P. Daigle , David Kim , Mark T. Stewart , Andrew L. Olson , Patrick J. Cloutier , Christopher W. Smith , Michael J. Hobday , Tessy Kanayinkal , Douglas H. Gubbin , Paul T. Rothstein , Joseph E. Cardinal , Jessica L. Foley , Christopher J. Plott
IPC分类号： A61B17/04
CPC分类号： A61B17/12 , A61B17/0057 , A61B17/12009 , A61B17/12013 , A61B17/122 , A61B17/128 , A61B17/1285 , A61B90/39 , A61B2017/00243 , A61B2017/00575 , A61B2017/12018 , A61B2017/306
摘要： The invention provides a system for occluding a left atrial appendage of a patient. The system can include a ring occluder that can be positioned around the left atrial appendage and a ring applicator to position the ring occluder with respect to the left atrial appendage. The system can also provide a tissue-grasping tool that is separable from the ring applicator tool.
摘要翻译：本发明提供一种用于闭塞患者的左心耳的系统。该系统可以包括可以围绕左心耳定位的环形闭塞器和环形施放器，以相对于左心耳定位环形闭塞器。该系统还可以提供可与环施加工具分离的组织抓取工具。

6. 发明授权

US08401225B2 Moving object segmentation using depth images 有权
标题翻译：使用深度图像移动物体分割
公开(公告)号：US08401225B2
公开(公告)日：2013-03-19
申请号：US13017626
申请日：2011-01-31
申请人： Richard Newcombe , Shahram Izadi , Otmar Hilliges , David Kim , David Molyneaux , Jamie Daniel Joseph Shotton , Pushmeet Kohli , Andrew Fitzgibbon , Stephen Edward Hodges , David Alexander Butler
发明人： Richard Newcombe , Shahram Izadi , Otmar Hilliges , David Kim , David Molyneaux , Jamie Daniel Joseph Shotton , Pushmeet Kohli , Andrew Fitzgibbon , Stephen Edward Hodges , David Alexander Butler
IPC分类号： G06K9/00
CPC分类号： G06T7/215 , G06T7/194 , G06T2207/10028 , G06T2207/30244
摘要： Moving object segmentation using depth images is described. In an example, a moving object is segmented from the background of a depth image of a scene received from a mobile depth camera. A previous depth image of the scene is retrieved, and compared to the current depth image using an iterative closest point algorithm. The iterative closest point algorithm includes a determination of a set of points that correspond between the current depth image and the previous depth image. During the determination of the set of points, one or more outlying points are detected that do not correspond between the two depth images, and the image elements at these outlying points are labeled as belonging to the moving object. In examples, the iterative closest point algorithm is executed as part of an algorithm for tracking the mobile depth camera, and hence the segmentation does not add substantial additional computational complexity.
摘要翻译：描述使用深度图像来移动物体分割。在一个示例中，从从移动深度相机接收的场景的深度图像的背景中分割移动物体。检索场景的先前深度图像，并使用迭代最近点算法与当前深度图像进行比较。迭代最近点算法包括对当前深度图像和先前深度图像之间对应的一组点的确定。在确定点集合期间，检测到一个或多个在两个深度图像之间不对应的离开点，并且将这些离散点处的图像元素标记为属于移动对象。在示例中，迭代最近点算法作为用于跟踪移动深度相机的算法的一部分被执行，因此分割不会增加实质的额外的计算复杂度。

7. 发明授权

US08072750B2 Top angled offset multi-media and user interface 有权
标题翻译：顶角偏移多媒体和用户界面
公开(公告)号：US08072750B2
公开(公告)日：2011-12-06
申请号：US12649363
申请日：2009-12-30
申请人： David Kim , Glen Kim , Alejandro Garfio
发明人： David Kim , Glen Kim , Alejandro Garfio
IPC分类号： G06F1/16
CPC分类号： G06F1/181
摘要： A computer enclosure with a user interface having an improved user-accessibility. The user interface is located at the upper front corner of the computer enclosure box. In the preferred embodiment, the interface is located on a protrusion extending out of the upper front corner of the enclosure box. The user interface has a surface plane that is preferably angled between 20-70 degrees to the ground to which the enclosure sits on. In other preferred embodiments, the user interface has a surface plane that is preferably angled between 40-60 degrees to the ground to which the enclosure sits on.
摘要翻译：具有用户接口具有改进的用户可访问性的计算机机箱。用户界面位于计算机机柜盒的上前角。在优选实施例中，接口位于从外壳盒的上前角延伸出的突出部上。用户界面具有一个表面平面，该表面平面优选地在与壳体所在的地面20-70度之间成角度。在其他优选实施例中，用户界面具有优选地在与罩体所在的地面成40-60度之间的表面平面。

8. 发明申请

US20110122687A1 TECHNIQUES FOR REDUCING DISTURBANCE IN A SEMICONDUCTOR DEVICE 有权
标题翻译：减少半导体存储器件中的干扰的技术
公开(公告)号：US20110122687A1
公开(公告)日：2011-05-26
申请号：US12624856
申请日：2009-11-24
申请人： Jungtae Kwon , David Kim , Sunil Bhardwaj
发明人： Jungtae Kwon , David Kim , Sunil Bhardwaj
IPC分类号： G11C7/00 , G11C7/06 , G11C16/34
CPC分类号： G11C7/02 , G11C7/06 , G11C7/08 , G11C7/18 , G11C11/406 , G11C11/40618 , G11C11/4091 , G11C11/4097 , G11C16/32 , G11C16/3418
摘要： Techniques for reducing disturbance in a semiconductor memory device are disclosed. In one particular exemplary embodiment, the techniques may be realized as a semiconductor memory device having reduced disturbance. The semiconductor memory device may comprise a plurality of memory cells arranged in arrays of rows and columns. The semiconductor memory device may also comprise a plurality of data sense amplifiers, coupled to the plurality of memory cells, configured to perform one or more operations during an operation/access cycle, wherein the operation/access cycle may comprise an operation segment and a disturbance recovery segment.
摘要翻译：公开了用于减少半导体存储器件中的干扰的技术。在一个特定的示例性实施例中，这些技术可以被实现为具有减小的干扰的半导体存储器件。半导体存储器件可以包括以行和列的阵列排列的多个存储器单元。半导体存储器件还可以包括耦合到多个存储器单元的多个数据读出放大器，被配置为在操作/访问周期期间执行一个或多个操作，其中操作/访问周期可以包括操作段和扰动恢复部分。

9. 发明申请

US20110043492A1 INPUT DEVICE AND DISPLAY SYSTEM HAVING THE SAME 有权
标题翻译：输入装置和显示系统
公开(公告)号：US20110043492A1
公开(公告)日：2011-02-24
申请号：US12544481
申请日：2009-08-20
申请人： Gary Elsasser , Jeff Zolnowsky , Michael Cochran , David Kim
发明人： Gary Elsasser , Jeff Zolnowsky , Michael Cochran , David Kim
IPC分类号： G06F3/033
CPC分类号： G06F3/03545 , G06F3/0428
摘要： An input device capable of optically communicating with an electronic apparatus is provided. The input device includes a light source, a force sensor, and a controller. The force sensor is configured to sense a force applied to a tip of the input device and generate a first sensing signal corresponding to the sensed force. The controller is electrically connected to the light source and the force sensor, and configured to receive the first sensing signal and control the light source to generate light pulses in response to the first sensing signal according to a predefined protocol.
摘要翻译：提供能够与电子设备进行光学通信的输入设备。输入装置包括光源，力传感器和控制器。力传感器被配置为感测施加到输入装置的尖端的力并产生对应于感测力的第一感测信号。控制器电连接到光源和力传感器，并且被配置为接收第一感测信号并且根据预定义的协议来控制光源以响应于第一感测信号而产生光脉冲。

10. 发明申请

US20060199554A1 Integration of fixed wireless terminal with broadcast radio receiving devices 失效
标题翻译：固定无线终端与广播无线电接收设备的集成
公开(公告)号：US20060199554A1
公开(公告)日：2006-09-07
申请号：US11180104
申请日：2005-07-12
申请人： Mike Kwon , David Kim , Sidney Park , Simon Yi
发明人： Mike Kwon , David Kim , Sidney Park , Simon Yi
IPC分类号： H03D5/00 , H04M1/00
CPC分类号： H04B1/3805 , H04H60/80 , H04H60/90
摘要： A system comprising: a broadcast radio receiving device configured to receive and provide broadcast audio-visual signals; and a fixed wireless terminal apparatus coupled to the broadcast radio receiving device, wherein the fixed wireless terminal apparatus manages and controls characteristics of the broadcast audio-visual signals.
摘要翻译：一种系统，包括：广播无线电接收装置，被配置为接收和提供广播视听信号; 以及耦合到所述广播无线电接收装置的固定无线终端装置，其中所述固定无线终端装置管理和控制所述广播视听信号的特性。

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