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1. 发明申请

US20120138469A1 MICROFLUIDIC DEVICES FOR TRANSVERSE ELECTROPHORESIS AND ISOELECTRIC FOCUSING 审中-公开
标题翻译：用于横向电泳和电致电聚焦的微流体装置
公开(公告)号：US20120138469A1
公开(公告)日：2012-06-07
申请号：US11939292
申请日：2007-11-13
申请人： Paul Yager , Mark Holl , Darrel J. Bell , James Brody , Catherine R. Cabrera , Andrew E. Kamholz , Katerina Macounova , Dong Qin
发明人： Paul Yager , Mark Holl , Darrel J. Bell , James Brody , Catherine R. Cabrera , Andrew E. Kamholz , Katerina Macounova , Dong Qin
IPC分类号： B01D57/02
CPC分类号： G01N27/44795 , G01N27/44769
摘要： Devices and methods are provided for separation of particles of a first selected electrophoretic mobility or isoelectric point from a fluid comprising particles of at least one other selected electrophoretic mobility or isoelectric point. The devices comprise a microchannel; electrodes to either side of the microchannel for applying a selected voltage to produce an electrical field across the microchannel orthogonal to the length of the microchannel; and outlets in said microchannel placed to receive outlet portions of the fluid containing enhanced concentrations of each type of particle. The devices may be used for particle detection, quantification, separation, mixing, dilution and concentration; to release, separate and detect interior particles of cells or organisms, and to separate particles such as proteins and microorganisms from biological fluids such as blood; or to separate and detect airborne contaminants such as bacterial warfare agents from air.
摘要翻译：提供了设备和方法，用于从包含至少一个其它选择的电泳迁移率或等电点的颗粒的流体分离第一选择的电泳迁移率或等电点的颗粒。所述装置包括微通道; 电极到微通道的任一侧，用于施加所选择的电压，以跨过与微通道长度正交的微通道产生电场; 并且所述微通道中的出口被设置成接收含有增强浓度的每种类型的颗粒的流体的出口部分。该装置可用于颗粒检测，定量，分离，混合，稀释和浓缩; 释放，分离和检测细胞或生物体的内部颗粒，并将诸如蛋白质和微生物的颗粒与生物液体如血液分离; 或从空气中分离和检测空气污染物，如细菌战剂。

2. 发明授权

US06482306B1 Meso- and microfluidic continuous flow and stopped flow electroösmotic mixer 失效
标题翻译：介质和微流体连续流动和停止流动电渗流混合器
公开(公告)号：US06482306B1
公开(公告)日：2002-11-19
申请号：US09404454
申请日：1999-09-22
申请人： Paul Yager , Mark R. Holl , Andrew Kamholz , Catherine Cabrera , Katerina Macounova
发明人： Paul Yager , Mark R. Holl , Andrew Kamholz , Catherine Cabrera , Katerina Macounova
IPC分类号： B01F1300
CPC分类号： B01F13/0076 , B01F13/0001 , B01F13/0005 , B01F13/0077 , B01L3/5027 , Y10T137/2087 , Y10T137/2191
摘要： An electroösmotic mixing device and a method for mixing one or more fluids for use in meso- or microfluidic device applications. The mixing device provides batch or continuous mixing of one or more fluids in meso- or microfluidic channels. An electric field is generated in the channel in substantial contact with chargeable surfaces therein. No alterations of the geometry of existing flow paths need be made, and the degree of mixing in the device can be controlled by the length of the electrodes, the flow rate past the electrodes, and the voltage applied to those electrodes. The degree of mixing is affected by choice of materials for the chargeable surface (in some cases by the selection of materials or coatings for channel walls) and the ionic strength of the fluids and the type and concentration of ions in the fluids. The ionic strength of fluids to be mixed is sufficiently low to allow electroosmotic flow. The method and device of this invention is preferably applied to fluids to having low ionic strength less than or equal to about 1 mM.
摘要翻译：一种电渗混合装置和用于混合用于中等或微流体装置应用的一种或多种流体的方法。混合装置在中等或微流体通道中提供一种或多种流体的间歇或连续混合。在通道中产生与其中的可充电表面实质接触的电场。不需要改变现有流路的几何形状，并且可以通过电极的长度，通过电极的流速和施加到这些电极的电压来控制装置中的混合程度。混合的程度受到可充电表面的材料选择（在某些情况下通过选择通道壁的材料或涂层）以及流体的离子强度以及流体中离子的类型和浓度的影响。要混合的流体的离子强度足够低以允许电渗流。本发明的方法和装置优选应用于具有小于或等于约1mM的低离子强度的流体。

3. 发明申请

US20120100451A1 METAL CO-CATALYST ENHANCER OF ELECTRO-OXIDATION OF ETHANOL 审中-公开
标题翻译：乙醇电氧化的金属催化剂增强剂
公开(公告)号：US20120100451A1
公开(公告)日：2012-04-26
申请号：US13379043
申请日：2010-06-18
申请人： Sanjeev Mukerjee , Qinggang He , Petr Krtil , Katerina Macounova
发明人： Sanjeev Mukerjee , Qinggang He , Petr Krtil , Katerina Macounova
IPC分类号： H01M8/22 , H01M8/08
CPC分类号： H01M4/9008 , H01M4/921 , H01M8/083 , H01M8/22 , H01M2300/0014
摘要： A process for the highly efficient oxidation of ethanol in fuel cells involves the addition of a metal co-catalyst oxidation enhancer to the fuel cell electrolyte in soluble form. The enhancer vastly improves the rate of ethanol ethanol oxidation and promotes oxidation of the C—C bond to CO2. The metal co-catalyst can adopt oxidation number II and oxidation number IV and forms a redox couple that promotes oxidation reactions at the anode. Embodiments of the invention include fuel cells, methods of their operation, and fuel cell electrolyte solutions for the efficient electro-oxidation of organic fuels including ethanol.
摘要翻译：用于在燃料电池中高效氧化乙醇的方法包括向可燃形式的燃料电池电解质中加入金属助催化剂氧化增强剂。增强剂大大提高了乙醇乙醇的氧化速率，促进了C-C键氧化成二氧化碳。金属助催化剂可以采用氧化Ⅻ和氧化Ⅳ，形成氧化还原对，促进阳极氧化反应。本发明的实施方案包括燃料电池，其操作方法和用于有机电氧化包括乙醇的有机燃料的燃料电池电解质溶液。

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