会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明授权
    • Expandable shielded vessel support
    • 可扩展屏蔽容器支架
    • US6010529A
    • 2000-01-04
    • US759877
    • 1996-12-03
    • Steve A. HerweckPeter GingrasPaul MartakosTheodore Karwoski
    • Steve A. HerweckPeter GingrasPaul MartakosTheodore Karwoski
    • A61F2/00A61F2/06A61F2/10A61F2/24A61F2/88A61L31/04A61L31/10A61F2/04
    • A61F2/07A61F2/06A61F2/88A61L31/04A61L31/10A61F2/105A61F2002/072A61F2240/001Y10S623/901
    • A radially expandable support body is enveloped within a cocoon. In a preferred construction, the support is a stent, and a tube of polymeric material, e.g. polytetrafluoroethylene (PTFE), passes through the interior of the stent body and is turned back upon itself over the stent to form a cuff. The assembly is then heated and the outer layer contacts and coalesces with the inner layer, closely surrounding the stent body within a folded envelope having a continuous and seamless end. In one embodiment, an end portion of the tube is expanded before folding back over the stent. The end portion, which becomes an exterior surface of the finished product, thus acquires a greater degree of porosity. Each end of the central tube may be so expanded, and folded back to seal all surfaces and both ends. The stent body itself may be a ring, or a short series of spaced-apart rings, or a wire or web, or a sheet possessing a number of apertures extending entirely through the sheet. The spaces or apertures are covered over or bridged by both the inner and outer polymer layers. The apertures, which may comprise under five to over eighty percent of the surface area of the stent, constitute regions or a grid of points through which the material is coalesced and continuously bonded, and around which strain is distributed by the support. These points or regions remain tacked together so expansion of the assembly does not delaminate the polymer or create flaps and pockets. In another embodiment, a two tube construction is cuffed and assembled into a similarly unitized and seamless stent. One tube is cuffed back, and the other tube covers the cuffed stent. In this embodiment both the tube thicknesses and porosities may differ substantially. For example the inner porosity may be selected to enhance blood flow or intimal regeneration, and the outer surface may have a porosity to encourage anchoring to external muscle tissue.
    • 径向可扩展的支撑体被包围在茧内。 在优选的结构中,支撑件是支架,以及聚合物材料管,例如。 聚四氟乙烯(PTFE)穿过支架主体的内部并在支架上自身转回以形成袖带。 然后将组件加热并且外层与内层接触并聚结,在具有连续和无缝端部的折叠外壳内紧密地围绕支架主体。 在一个实施例中,管的端部在折回到支架之前膨胀。 成为成品的外表面的端部因此获得更大程度的孔隙率。 中心管的每个端部可以如此膨胀,并且被折回以密封所有表面和两端。 支架主体本身可以是一个环,或一系列间隔开的环,或者线或腹板,或者具有完全贯穿片材的多个孔的片。 空间或孔被内聚合物层和外聚合物层覆盖或桥接。 可以包括支架表面积的五到八十成以上的孔构成区域或网格,通过该点或网格将材料聚结并连续地结合,并且通过支撑分布在哪个应变附近。 这些点或区域保持粘合在一起,因此组件的膨胀不会分解聚合物或产生襟翼和口袋。 在另一个实施例中,将双管结构压合并组装成相似的单元化且无缝的支架。 一根管子被套在后面,另一根管子覆盖着袖口支架。 在该实施例中,管的厚度和孔隙度可能基本上不同。 例如,可以选择内部孔隙率以增强血流或内膜再生,并且外表面可以具有孔隙度以促进锚定到外部肌肉组织。
    • 3. 发明授权
    • Vascular endoprosthesis and method
    • 血管内假体和方法
    • US06423089B1
    • 2002-07-23
    • US09296349
    • 1999-04-22
    • Peter GingrasPaul MartakosTheodore KarwoskiSteve A. Herweck
    • Peter GingrasPaul MartakosTheodore KarwoskiSteve A. Herweck
    • A61F206
    • A61F2/82A61F2/07A61F2/90A61F2/958A61L31/048C08L27/18
    • A vascular endoprosthesis is formed of a tubular liner preform with a continuous surface and having a diameter smaller than that of an intended vessel. The liner is inserted to a treatment site, and its sheet material undergoes a radially-directed expansion to a final size that fits the vessel. Insertion and in situ expansion are achieved using a catheter assembly in which either an internal stent, such as a stiff-filament helically woven tube, or an inflatable balloon urge the liner preform outwardly against the inner wall of the vessel. The stent, or one or more simple internal snap-rings anchor the expanded liner in place. The expanded liner is porous, or becomes more porous during expansion, and one or more aspects of its porosity are tailored to the intended treatment goal of immobilizing treatment material, isolating cells, or permitting controlled permeation of selected materials.
    • 血管内假体由具有连续表面并且直径小于预期血管的直径的管状衬垫预制件形成。 将衬垫插入到处理部位,并且其片材经历径向膨胀至适合容器的最终尺寸。 使用导管组件实现插入和原位扩张,其中内部支架例如刚性丝状螺旋编织管或可膨胀气囊将衬垫预制件向外压靠在容器的内壁上。 支架或一个或多个简单的内部卡环将扩张的衬垫固定就位。 膨胀的衬垫是多孔的,或在膨胀期间变得更多孔,并且其孔隙率的一个或多个方面是针对固定化处理材料,分离细胞或允许所选材料的受控渗透的预期治疗目标。
    • 6. 发明授权
    • Expandable shielded vessel support
    • 可扩展屏蔽容器支架
    • US06270523B1
    • 2001-08-07
    • US09419467
    • 1999-10-15
    • Steve A. HerweckPeter GingrasPaul MartakosTheodore Karwoski
    • Steve A. HerweckPeter GingrasPaul MartakosTheodore Karwoski
    • A61F206
    • A61F2/07A61F2/06A61F2/105A61F2/88A61F2002/072A61F2240/001A61L31/04A61L31/10C08L27/18Y10S623/901
    • A radially expandable support body is enveloped within a cocoon. In a preferred construction, the support is a stent, and a tube of polymeric material, e.g., polytetraeluoroethylene (PTFE), passes through the interior of the stent body and is turned back upon itself over the stent to form a cuff. The assembly is then heated and the outer layer contacts and coalesces with the inner layer, closely surrounding the stent body within a folded envelope having a continuous and seamless end. In one embodiment, an end portion of the tube is expanded before folding back over the-stent. The end portion, which becomes an exterior surface of the finished product, thus acquires a greater degree of porosity. Each end of the central tube may be so expanded, and folded back to seal all surfaces and both ends. The stent body itself may be a ring, or a short series of spaced-apart rings, or a wire or web, or a sheet possessing a number of apertures extending entirely through the sheet. The spaces or apertures are covered over or bridged by both the inner and outer polymer layers. The apertures, which may comprise under five to over eighty percent of the surface area of the stent, constitute regions or a grid of points through which the material is coalesced and continuously bonded, and around which strain is distributed by the support. These points or regions remain tacked together so expansion of the assembly does not delaminate the polymer or create flaps and pockets. In another embodiment, a two tube construction is cuffed and assembled into a similarly unitized and seamless stent. One tube is cuffed back, and the other tube covers the cuffed stent. In this embodiment both the tube thicknesses and porosities may differ substantially. For example the inner porosity may be selected to enhance blood flow or intimal regeneration, and the outer surface may have a porosity to encourage anchoring to external muscle tissue.
    • 径向可扩展的支撑体被包围在茧内。 在优选的结构中,支撑件是支架,并且聚合物材料管例如聚多异氰酸乙烯(PTFE)穿过支架主体的内部并且在其上自我转过支架以形成袖带。 然后将组件加热并且外层与内层接触并聚结,在具有连续和无缝端部的折叠外壳内紧密地围绕支架主体。 在一个实施例中,管的端部在折叠回支架之前膨胀。 成为成品的外表面的端部因此获得更大程度的孔隙率。 中心管的每个端部可以如此膨胀,并且被折回以密封所有表面和两端。 支架主体本身可以是一个环,或一系列间隔开的环,或者线或腹板,或者具有完全贯穿片材的多个孔的片。 空间或孔被内聚合物层和外聚合物层覆盖或桥接。 可以包括支架表面积的五到八十成以上的孔构成区域或网格,通过该点或网格将材料聚结并连续地结合,并且通过支撑分布在哪个应变附近。 这些点或区域保持粘合在一起,因此组件的膨胀不会分解聚合物或产生襟翼和口袋。 在另一个实施例中,将双管结构压合并组装成相似的单元化且无缝的支架。 一根管子被套在后面,另一根管子覆盖着袖口支架。 在该实施例中,管的厚度和孔隙度可能基本上不同。 例如,可以选择内部孔隙率以增强血流或内膜再生,并且外表面可以具有孔隙度以促进锚定到外部肌肉组织。