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1. 发明授权

US5957974A Stent graft with braided polymeric sleeve 失效
标题翻译：支架移植与编织聚合物套管
公开(公告)号：US5957974A
公开(公告)日：1999-09-28
申请号：US946906
申请日：1997-10-08
申请人： Paul J. Thompson , George W. Du
发明人： Paul J. Thompson , George W. Du
IPC分类号： A61F2/00 , A61F2/90 , B29C35/02 , B29C53/58 , B29C63/18 , B29D23/00 , D04C1/06 , A61F2/06
CPC分类号： A61F2/90 , A61F2/07 , B29D23/001 , D04C1/06 , A61F2/0077 , A61F2002/072 , A61F2002/075 , A61F2002/3008 , A61F2002/30448 , A61F2210/0076 , A61F2220/005 , A61F2220/0075 , A61F2240/001 , A61F2250/0098 , B29C35/02 , B29C53/58 , B29C63/18 , B29K2105/0827 , B29K2105/0845 , B29K2223/065 , B29K2223/12 , B29K2227/18 , B29K2267/00 , B29K2271/00 , B29K2275/00 , B29K2281/06 , B29L2023/007 , D10B2509/06
摘要： A stent graft for transluminal implantation includes a resilient tubular interbraided latticework of metal or polymeric monofilaments, a tubular interbraided sleeve of polymeric multifilament yarns, and an adhesive layer between the sleeve and latticework for bonding them together. The monofilaments and multifilament yarns are arranged in respective sets of axially spaced apart and oppositely directed helices, concentric on a common axis of the stent graft. The respective braid angles of the monofilaments and multifilament yarns are carefully matched to ensure that the latticework and sleeve behave according to substantially the same relationship governing the amount of radial reduction that accompanies a given axial elongation. According to a process for fabricating the stent graft, the latticework and sleeve are braided and thermally set independently, then bonded to one another by a silicone polymer adhesive applied evenly to the latticework in a liquid spray that also incorporates an organic solvent. Especially preferred yarns are composed of essentially untwisted filaments that define non-circular yarn cross sections. Alternative stent graft constructions feature exterior and interior sleeves on opposite sides of the latticework, two or more sleeves axially spaced from one another on the same latticework, a latticework formed of a recovery metal, and a plastically deformable latticework.
摘要翻译：用于腔内植入的支架移植物包括金属或聚合单丝的弹性管状插入式网状结构，聚合复丝纱线的管状插入式套管以及用于将它们结合在一起的套筒和网格之间的粘合剂层。单丝和复丝纱布置在相应组的轴向间隔开和相对定向的螺旋上，在支架移植物的公共轴上同心。单丝和多丝纱线的相应编织角度被仔细地匹配，以确保网格和套筒根据与规定的轴向伸长率相关的径向减小量的基本相同的关系来表现。根据制造支架移植物的方法，网格和套管被独立地编织和热定形，然后通过以同样结合有机溶剂的液体喷雾均匀地施加到网格上的硅氧烷聚合物粘合剂彼此粘合。特别优选的纱线由限定非圆形纱线横截面的基本上未扭绞的长丝组成。替代的支架移植物构造具有在网格的相对侧上的外部和内部袖子，在同一格子上彼此轴向间隔开的两个或更多个袖子，由恢复金属形成的网格和可塑性变形的网格。

2. 发明授权

US06500203B1 Process for making stent graft with braided polymeric sleeve 失效
标题翻译：用编织聚合物套管制作支架移植物的方法
公开(公告)号：US06500203B1
公开(公告)日：2002-12-31
申请号：US09321181
申请日：1999-05-27
申请人： Paul J. Thompson , George W. Du
发明人： Paul J. Thompson , George W. Du
IPC分类号： A61F206
CPC分类号： A61F2/90 , A61F2/0077 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2002/3008 , A61F2002/30448 , A61F2210/0076 , A61F2220/005 , A61F2220/0075 , A61F2240/001 , A61F2250/0098 , B29C35/02 , B29C53/58 , B29C63/18 , B29D23/001 , B29K2105/0827 , B29K2105/0845 , B29K2223/065 , B29K2223/12 , B29K2227/18 , B29K2267/00 , B29K2271/00 , B29K2275/00 , B29K2281/06 , B29L2023/007 , D04C1/06 , D10B2509/06
摘要： A stent graft for transluminal implantation includes a resilient tubular interbraided latticework of metal or polymeric monofilaments, a tubular interbraided sleeve of polymeric multifilament yarns, and an adhesive layer between the sleeve and latticework for bonding them together. The monofilaments and multifilament yarns are arranged in respective sets of axially spaced apart and oppositely directed helices, concentric on a common axis of the stent graft. The respective braid angles of the monofilaments and multifilament yarns are carefully matched to ensure that the latticework and sleeve behave according to substantially the same relationship governing the amount of radial reduction that accompanies a given axial elongation. According to a process for fabricating the stent graft, the latticework and sleeve are braided and thermally set independently, then bonded to one another by a silicone polymer adhesive applied evenly to the latticework in a liquid spray that also incorporates an organic solvent. Especially preferred yarns are composed of essentially untwisted filaments that define non-circular yarn cross sections. Alternative stent graft constructions feature exterior and interior sleeves on opposite sides of the latticework, two or more sleeves axially spaced from one another on the same latticework, a latticework formed of a recovery metal, and a plastically deformable latticework.
摘要翻译：用于腔内植入的支架移植物包括金属或聚合单丝的弹性管状插入式网状结构，聚合复丝纱线的管状插入式套管以及用于将它们结合在一起的套筒和网格之间的粘合剂层。单丝和复丝纱布置在相应组的轴向间隔开和相对定向的螺旋上，在支架移植物的公共轴上同心。单丝和多丝纱线的相应编织角度被仔细地匹配，以确保网格和套筒根据与规定的轴向伸长率相关的径向减小量的基本相同的关系来表现。根据制造支架移植物的方法，网格和套管被独立地编织和热定形，然后通过以同样结合有机溶剂的液体喷雾均匀地施加到网格上的硅氧烷聚合物粘合剂相互结合。特别优选的纱线由限定非圆形纱线横截面的基本上未扭绞的长丝组成。替代的支架移植物构造具有在网格的相对侧上的外部和内部袖子，在同一格子上彼此轴向间隔开的两个或更多个袖子，由恢复金属形成的网格和可塑性变形的网格。

3. 发明授权

US5906641A Bifurcated stent graft 失效
标题翻译：分叉支架移植
公开(公告)号：US5906641A
公开(公告)日：1999-05-25
申请号：US22256
申请日：1998-02-11
申请人： Paul J. Thompson , George W. Du
发明人： Paul J. Thompson , George W. Du
IPC分类号： A61F2/06 , A61F2/90 , A61F2/04
CPC分类号： A61F2/90 , A61F2/07 , A61F2/856 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2220/005 , A61F2220/0075 , A61F2230/001 , A61F2230/0017 , A61F2230/005
摘要： A bifurcated stent graft implantable in branched internal passageways includes an open-frame stent latticework formed of helically wound structural strands, and a graft sleeve formed of interwoven textile strands. The sleeve is substantially impervious to fluids and is adjustable along with the graft between a nominal state and radially-reduced axially-elongated state, according to substantially the same relationship of radial reduction versus axial elongation. The sleeve and stent are bonded to one another at least at proximal and distal end regions of the stent graft. The sleeve preferably is surrounded by the stent, and incorporates a flow dividing feature in the form of an axially extending seam. The seam brings together portions of the sleeve that otherwise would be circumferentially spaced apart in the tubular sleeve shape. The stent latticework and graft sleeve can be coextensive, the sleeve can extend distally beyond the latticework, or the latticework can extend proximally beyond the sleeve, depending on the intended use. In other alternative embodiments, the sleeve can surround the latticework.
摘要翻译：可植入分支内部通道的分叉式支架植入物包括由螺旋缠绕的结构股形成的开放式框架支架网格，以及由交织的纺织股线形成的移植套管。套管基本上不能渗透流体，并且根据径向压缩与轴向伸长的基本相同的关系，可随着移植物在标称状态和径向减小的轴向细长状态之间调节。至少在支架移植物的近端和远端区域，套管和支架彼此粘合。套管优选地被支架包围，并且包括呈轴向延伸的接缝形式的分流部件。接缝将套筒的不同部分沿圆周方向间隔开形成管状套筒形状。支架网格和移植套筒可以共同延伸，套管可以向远端延伸超过网格，或根据预期用途，网格可以向近端延伸超出套管。在其他替代实施例中，套筒可围绕网格。

4. 发明授权

US09962278B2 Modular gastrointestinal prostheses 有权
公开(公告)号：US09962278B2
公开(公告)日：2018-05-08
申请号：US13493144
申请日：2012-06-11
申请人： Kedar R. Belhe , Paul J. Thompson
发明人： Kedar R. Belhe , Paul J. Thompson
IPC分类号： A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要： A modular system for therapy within a gastrointestinal system. The system includes anchoring or attachment functionality embodied in a low-profile implant technology and removable therapy components, which can be reversibly attached to these low-profile implants to accomplish various therapies. This modular design allows the physician to tailor the therapy to the patient's needs. The modular system has the potential to create conduits for diversion and/or restriction of food and organ secretions and to facilitate the treatment of metabolic disorders such as obesity and T2DM.

5. 发明授权

US08900289B2 Stent with dual support structure 有权
标题翻译：支架双支撑结构
公开(公告)号：US08900289B2
公开(公告)日：2014-12-02
申请号：US13198770
申请日：2011-08-05
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/06 , A61F2/91 , A61F2/915
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2230/0013 , A61F2230/0054 , A61F2250/001
摘要： A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.
摘要翻译：管腔内支架包括具有未展开直径并且可扩张至扩大直径的网状管。管包括在第一和第二端之间延伸的结构梁。当管从未展开的直径变大到扩大的直径时，结构梁从第一几何变化到第二几何形状。结构梁包括第一和第二纵向元件，每个第一和第二纵向元件至少部分地在第一和第二端之间延伸并且在第一和第二元件之间具有间隔。当管从未展开的直径改变到扩大的直径时，所述第一和第二元件中的每一个从第一几何形状变化到第二几何形状，以使间隔保持基本上不变，因为管从未展开的直径变大到扩大的直径直径。

6. 发明授权

US08702641B2 Gastrointestinal prostheses having partial bypass configurations 有权
标题翻译：具有部分旁路构造的胃肠假体
公开(公告)号：US08702641B2
公开(公告)日：2014-04-22
申请号：US12986268
申请日：2011-01-07
申请人： Kedar R. Belhe , Paul J. Thompson
发明人： Kedar R. Belhe , Paul J. Thompson
IPC分类号： A61B19/00
CPC分类号： A61F5/0076 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要： A system of components may be used separately or in combination to create partial bypass of food, stomach and intestinal secretions and digestive enzymes. The systems are designed to be modular so as to allow the physicians to quickly replace certain elements to tailor the amount of material bypassed, the restriction applied to food passage, and the origin and destination of bypass according to the patient's individualized clinical needs.
摘要翻译：组分体系可以单独使用或组合使用以产生食物，胃和肠分泌物和消化酶的部分旁路。这些系统被设计为模块化的，以便允许医生根据患者的个性化临床需要，迅速地替换某些元件以调整旁路材料的量，应用于食物通过的限制以及旁路的起点和目的地。

7. 发明申请

US20120271406A1 Stent With Enhanced Friction 审中-公开
标题翻译：支架增强摩擦
公开(公告)号：US20120271406A1
公开(公告)日：2012-10-25
申请号：US13535413
申请日：2012-06-28
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61F2/86 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/958 , A61F2002/91541 , A61F2002/91558 , A61F2002/9522 , A61F2002/9583 , A61F2230/0013 , A61F2230/0063 , A61F2230/0069 , A61F2240/001 , A61F2250/0025 , Y10S623/901 , Y10S623/921
摘要： A stent for placement in a body lumen is fabricated by forming a tube having an un-deployed diameter sized for the tube to be placed on a deployment balloon and advanced through a body lumen to a deployment site. The tube is expandable upon inflation of the balloon to an enlarged diameter sized for the tube to be retained within the lumen at the site upon deflation and withdrawal of the balloon. The tube has a stent axis extending between first and second axial ends of the tube. The tube has an exterior surface and an interior surface. The tube is polished to polish the exterior surface to a smooth surface finish and with at least a portion of the interior surface having a rough surface finish rougher than the surface finish of the exterior surface.
摘要翻译：用于放置在体腔中的支架通过形成具有未展开的直径的管来制造，所述管的尺寸适于管放置在展开气囊上并且通过体腔前进到展开部位。当气囊膨胀时，管可膨胀到扩大的直径，其尺寸适于使气囊在气囊收缩和抽出时在该位置保留在管腔内。管具有在管的第一和第二轴向端之间延伸的支架轴线。管具有外表面和内表面。管被抛光以抛光外表面以光滑的表面光洁度，并且内表面的至少一部分具有比外表面的表面光洁度更粗糙的粗糙表面光洁度。

8. 发明申请

US20120065571A1 EXPANDABLE PYLORIC ANCHORS AND METHODS FOR SECURING INTESTINAL BYPASS SLEEVES 审中-公开
标题翻译：可扩展的PYLORIC锚杆及其安装方法
公开(公告)号：US20120065571A1
公开(公告)日：2012-03-15
申请号：US13298867
申请日：2011-11-17
申请人： Paul J. Thompson , Kedar R. Belhe , Alex Grafov
发明人： Paul J. Thompson , Kedar R. Belhe , Alex Grafov
IPC分类号： A61M5/00
CPC分类号： A61F5/0076 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要： A gastrointestinal device for implanting within a patient's gastrointestinal tract includes first and second expandable anchoring rings configured to be disposed on either side of a patient's pylorus. The first expandable anchoring ring has a collapsed configuration and an expanded configuration, wherein in the expanded configuration the first expandable anchoring ring has a diameter larger than a maximum opening diameter of the pylorus. The second expandable anchoring ring also has a collapsed configuration and an expanded configuration, wherein in the expanded configuration the second expandable anchoring ring has a diameter larger than a maximum opening diameter of the pylorus. An intestinal bypass sleeve couples the first expandable anchoring ring and the second expandable anchoring ring, so as to allow a distance between the anchoring rings to exceed a width of the pylorus.
摘要翻译：用于植入患者胃肠道内的胃肠装置包括被配置为设置在患者幽门的任一侧上的第一和第二可扩张锚定环。第一可膨胀锚固环具有收缩构型和膨胀构型，其中在膨胀构型中，第一可膨胀锚定环的直径大于幽门的最大开口直径。第二可膨胀锚固环还具有收缩构型和膨胀构型，其中在膨胀构型中，第二可膨胀锚定环的直径大于幽门的最大开口直径。肠旁路套管将第一可膨胀锚固环和第二可膨胀锚固环联接，以便允许锚定环之间的距离超过幽门的宽度。

9. 发明申请

US20100228338A1 STENTS WITH TAPERED STRUTS 审中-公开
标题翻译：带扭头的手柄
公开(公告)号：US20100228338A1
公开(公告)日：2010-09-09
申请号：US12611114
申请日：2009-11-02
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/89 , A61F2002/91508 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2210/0014 , A61F2230/0013 , A61F2230/0054 , A61F2250/0036
摘要： A stent may include a stent body having a stent axis. The stent body may include structural members defining openings through the stent body. The structural members are provided with regions having different widths. The relative sizes of the widths are selected to control the length of the stent body as the stent body is radially expanded from an undeployed orientation to a deployed orientation. In one embodiment, the regions having different widths are provided by tapering the widths of selected segments of the structural member.
摘要翻译：支架可以包括具有支架轴线的支架主体。支架主体可以包括限定通过支架主体的开口的结构构件。结构构件设置有具有不同宽度的区域。选择宽度的相对尺寸来控制支架主体的长度，因为支架主体从未部署的取向径向膨胀到展开方向。在一个实施例中，具有不同宽度的区域通过使结构构件的选定段的宽度变窄来提供。

10. 发明申请

US20100087912A1 STENT WITH DUAL SUPPORT STRUCTURE 有权
标题翻译：具有双重支持结构的STENT
公开(公告)号：US20100087912A1
公开(公告)日：2010-04-08
申请号：US12633246
申请日：2009-12-08
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/82
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2230/0013 , A61F2230/0054 , A61F2250/001
摘要： A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.
摘要翻译：管腔内支架包括具有未展开直径并且可扩张至扩大直径的网状管。管包括在第一和第二端之间延伸的结构梁。当管从未展开的直径变大到扩大的直径时，结构梁从第一几何变化到第二几何形状。结构梁包括第一和第二纵向元件，每个第一和第二纵向元件至少部分地在第一和第二端之间延伸并且在第一和第二元件之间具有间隔。当管从未展开的直径改变到扩大的直径时，所述第一和第二元件中的每一个从第一几何形状变化到第二几何形状，以使间隔保持基本上不变，因为管从未展开的直径变大到扩大的直径直径。

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