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    • 1. 发明申请
    • BRANCHED COPOLYMERS, COMPOSITION AND USES
    • 分支共聚物,组合物和用途
    • US20120108679A1
    • 2012-05-03
    • US13148472
    • 2010-02-09
    • Paul Hugh FindlayBrodyck James Lachlan RoylesNeil John SimpsonSharon ToddSteven Paul RannardJonathan Victor Mark WeaverRoselyne Marie Andree Baudry
    • Paul Hugh FindlayBrodyck James Lachlan RoylesNeil John SimpsonSharon ToddSteven Paul RannardJonathan Victor Mark WeaverRoselyne Marie Andree Baudry
    • A61K47/32C08L47/00C09D147/00C09D11/00C10M145/14C02F5/00C09K5/00C09K15/12C09K15/06C08F236/20C09J147/00
    • C08F2/38C08F212/08C08F212/36C08F220/18C08F222/1006C08F2220/1825C08F220/20C08F220/06C08F2222/1013C08F226/10
    • The present invention relates to a branched copolymer comprising a hydrophilic component obtainable by an addition polymerisation process and compositions and uses thereof said copolymer comprising: i) a residue of at least one monofunctional monomer comprising one polymerisable double bond per molecule and a molecular weight of less than 1000 Daltons; ii) a residue of at least one multifunctional monomer comprising at least two polymerisable double bonds per molecule and a molecular weight of less than 1000 Daltons; and wherein the end termini of the copolymer chains comprise one or more of a residue of a chain transfer agent; an initiator or a terminal group derived from a termination reaction; wherein; the molar ratio of the monofunctional monomer to multifunctional monomer is between 50:1 to 2.5:1 respectively; and wherein the hydrophilic component is comprised of at least 1 mole % of one or more residue of a multifunctional monomer and/or one or more residue of a chain transfer agent comprised of a hydrophilic monomer each with a solubility of 0.18 w/w % in water; and wherein the residue of the at least one monofunctional monomer with a molecular weight of less than 1000 Daltons is selected from the group comprising: vinyl acids, vinyl acid esters, vinyl aryl compounds, vinyl acid anhydrides, vinyl amides, vinyl ethers, vinyl amines, vinyl aryl amines, vinyl nitriles, vinyl ketones, and derivatives thereof; hydroxyl-containing monomers and monomers which can be post-reacted to form hydroxyl groups; acid-containing or acid functional monomers; zwitterionic monomers; quaternised amino monomers, oligomeric monomers; and corresponding allyl monomers of the aforesaid vinyl monomers.
    • 本发明涉及包含通过加成聚合方法获得的亲水性组分的支链共聚物及其组合物和用途,所述共聚物包含:i)至少一种单分子的功能单体的残基,其每分子包含一个可聚合双键,分子量较小 超过1000道尔顿; ii)至少一种多官能单体的残基,每个分子包含至少两个可聚合双键,分子量小于1000道尔顿; 并且其中共聚物链的末端包含一个或多个链转移剂的残基; 来自终止反应的引发剂或末端基团; 其中; 单官能单体与多官能单体的摩尔比分别为50:1至2.5:1; 并且其中所述亲水组分由至少1摩尔%的多官能单体的一个或多个残基和/或链转移剂的一个或多个残基组成,所述链转移剂由亲水性单体组成,每个亲水性单体的溶解度为0.18w / w% 水; 并且其中分子量小于1000道尔顿的至少一种单官能单体的残基选自:乙烯基酸,乙烯基酸酯,乙烯基芳基化合物,乙烯基酸酐,乙烯基酰胺,乙烯基醚,乙烯基胺 乙烯基芳基胺,乙烯基腈,乙烯基酮及其衍生物; 含羟基的单体和可以后反应形成羟基的单体; 含酸或酸官能单体; 两性离子单体; 季铵化氨基单体,低聚单体; 和上述乙烯基单体的相应的烯丙基单体。
    • 2. 发明申请
    • BRANCHED COPOLYMERS, COMPOSITIONS AND USES
    • 分支共聚物,组合物和用途
    • US20120108678A1
    • 2012-05-03
    • US13148471
    • 2010-02-09
    • Paul Hugh FindlayBrodyck James Lachlan RoylesNeil John SimpsonSharon ToddSteven Paul RannardJonathan Victor Mark WeaverRoselyne Marie Andree Baudry
    • Paul Hugh FindlayBrodyck James Lachlan RoylesNeil John SimpsonSharon ToddSteven Paul RannardJonathan Victor Mark WeaverRoselyne Marie Andree Baudry
    • A61K47/32C08L47/00C09D147/00C09J147/00C09K15/12C02F5/00C10M107/42C10M107/28C09K5/00C09K15/28C08F236/20C09D11/00
    • C08F2/38C08F212/08C08F212/36C08F220/18C08F222/1006C08F2220/1825C08F220/20C08F220/06C08F2222/1013C08F226/10
    • The present invention relates to a branched copolymer obtainable by an addition polymerisation process and uses and compositions thereof comprising: i) a residue of at least one monofunctional monomer comprising one polymerisable double bond per molecule and a molecular weight of less than 1000 Daltons; ii) a residue of at least one multifunctional monomer comprising at least two polymerisable double bonds per molecule and a molecular weight of less than 1000 Daltons; and wherein the end termini of the copolymer chains comprise one or more of a residue of a chain transfer agent; an initiator or a terminal group derived from a termination reaction; wherein; the molar ratio of the monofunctional monomer to multifunctional monomer is between 50:1 to 2.5:1 respectively; and wherein the hydrophilic component is comprised of at least 1 mole % of a combination of a monofunctional monomer, and a multifunctional monomer and/or a chain transfer agent when compared to the total content of monofunctional monomer which is/are comprised of hydrophilic component each with a solubility of 0.18 w/w % in water at 20° C.; and wherein the residue of the at least one monofunctional monomer with a molecular weight of less than 1000 daltons is selected from the group comprising: vinyl acids, vinyl acid ester, vinyl aryl compounds, vinyl acid anhydrides, vinyl amides, vinyl ethers, vinyl amines, vinyl aryl amines, vinyl nitriles, vinyl ketones, and derivatives thereof; hydroxyl-containing monomers and monomers which can be post-reacted to form hydroxyl groups; acid-containing or acid functional monomers; zwitterionic monomers; quaternised amino monomers, oligomeric monomers; and corresponding allyl monomers of the aforesaid vinyl monomers.
    • 本发明涉及可通过加成聚合方法获得的支链共聚物及其用途及其组合物,其包含:i)至少一种单分子的残基,其每分子包含一个可聚合的双键,分子量小于1000道尔顿; ii)至少一种多官能单体的残基,每个分子包含至少两个可聚合双键,分子量小于1000道尔顿; 并且其中共聚物链的末端包含一个或多个链转移剂的残基; 来自终止反应的引发剂或末端基团; 其中; 单官能单体与多官能单体的摩尔比分别为50:1至2.5:1; 并且其中亲水性组分由至少1摩尔%的单官能单体和多官能单体和/或链转移剂的组合组成,当与由各亲水组分组成的单官能单体的总含量相比时 溶解度为0.18W / W%,在20℃的水中。 并且其中所述至少一种分子量小于1000道尔顿的单官能单体的残基选自:乙烯基酸,乙烯基酸酯,乙烯基芳基化合物,乙烯基酸酐,乙烯基酰胺,乙烯基醚,乙烯基胺 乙烯基芳基胺,乙烯基腈,乙烯基酮及其衍生物; 含羟基的单体和可以后反应形成羟基的单体; 含酸或酸官能单体; 两性离子单体; 季铵化氨基单体,低聚单体; 和上述乙烯基单体的相应的烯丙基单体。
    • 3. 发明申请
    • AMPHIPHILIC BRANCHED COPOLYMER, METHODS OF PREPARATION, EMULSIONS, AND USES
    • 分散共聚物,制备方法,乳液和用途
    • US20120059069A1
    • 2012-03-08
    • US13266745
    • 2010-04-28
    • Paul Hugh FindlayBrodyck James LachlanNeil John SimpsonSharon ToddRoselyne Marie Andree BaudrySteven Paul RannardJonathan Victor Mark Weaver
    • Paul Hugh FindlayBrodyck James LachlanNeil John SimpsonSharon ToddRoselyne Marie Andree BaudrySteven Paul RannardJonathan Victor Mark Weaver
    • A61K47/32A23D7/005C08L39/00C08F236/20A61K8/81
    • C08F220/26
    • The present invention relates to an amphiphilic branched copolymer obtainable by an addition polymerisation process, the method of production of same and uses thereof as emulsions wherein said polymer comprises: at least two chains which are covalently linked by a bridge other than at their ends; and wherein the at least two chains comprise at least one ethylenically monounsaturated monomer, and wherein the bridge comprises at least one ethylenically polyunsaturated monomer; and wherein the polymer comprises a residue of a chain transfer agent and optionally a residue of an initiator, and wherein at least one of the monounsaturated monomer(s) and polyunsaturated monomer(s) and chain transfer agent(s) is a hydrophilic residue; and at least one of one of the monounsaturated monomer(s) and polyunsaturated monomer(s) and chain transfer agent(s) is a hydrophobic residue, and wherein the mole ratio of polyunsaturated monomer(s) to monounsaturated monomer(s) is in a range of from 1:100 to 1:4, and wherein at least one of the monounsaturated monomer(s) and polyunsaturated monomer(s) and chain transfer agent(s) comprises a moiety that is capable of responding to an external stimuli thereby creating a physical or chemical change in the solubility of the said moiety; and wherein the air-water surface tension of the polymer changes from between 35 mN/m to 60 mN/m upon application of the external stimulus.
    • 本发明涉及通过加成聚合方法获得的两亲性支链共聚物,其制备方法及其用途作为乳液,其中所述聚合物包含:至少两个通过桥以外的桥共价连接的链; 并且其中所述至少两条链包含至少一种烯属单不饱和单体,并且其中所述桥包含至少一种烯键式多不饱和单体; 并且其中所述聚合物包含链转移剂的残基和任选的引发剂的残基,并且其中所述单不饱和单体和多不饱和单体和链转移剂中的至少一种是亲水性残基; 并且单不饱和单体和多不饱和单体和链转移剂中的至少一种是疏水性残基,并且其中多不饱和单体与单不饱和单体的摩尔比在 1:100至1:4的范围,并且其中至少一种单不饱和单体和多不饱和单体和链转移剂包含能够响应于外部刺激的部分, 造成所述部分的溶解度的物理或化学变化; 并且其中当施加外部刺激时聚合物的空气 - 水表面张力从35mN / m至60mN / m变化。
    • 4. 发明申请
    • BRANCHED COPOLYMERS, COMPOSITION AND USES
    • 分支共聚物,组合物和用途
    • US20110313054A1
    • 2011-12-22
    • US13148470
    • 2010-02-09
    • Paul Hugh FindlayBrodyck James Lachlan RoylesNeil John SimpsonSharon ToddSteven Paul RannardJonathan Victor Mark WeaverRoselyne Marie Andree Baudry
    • Paul Hugh FindlayBrodyck James Lachlan RoylesNeil John SimpsonSharon ToddSteven Paul RannardJonathan Victor Mark WeaverRoselyne Marie Andree Baudry
    • A61K47/32C08L47/00C09D147/00C10L1/19C10M145/14C02F5/10C09K5/00C09K3/00C08F236/20C09J147/00
    • C08F2/38C08F212/08C08F212/36C08F220/18C08F222/1006C08F2220/1825C08F220/20C08F220/06C08F2222/1013C08F226/10
    • The present invention relates to a branched copolymer obtainable by an addition polymerisation process and uses and compositions thereof comprising a hydrophilic component, said polymer comprising: i) a residue of at least one monofunctional monomer comprising one polymerisable double bond per molecule and a molecular weight of less than 1000 Daltons; ii) a residue of at least one multifunctional monomer comprising at least two polymerisable double bonds per molecule and a molecular weight of less than 1000 Daltons; and wherein the end termini of the copolymer chains comprise one or more of a residue of a chain transfer agent; an initiator or a terminal group derived from a termination reaction; wherein; the molar ratio of the monofunctional monomer to multifunctional monomer is between 50:1 to 2.5:1 respectively; and wherein the hydrophilic component is comprised solely of at least 1 mole % of one or more monofunctional monomer which is/are comprised of hydrophilic monomer each with a solubility of 0.18 w/w % in water at 20° C.; and wherein the residue of the at least one monofunctional monomer with a molecular weight of less than 1000 daltons is selected from the group comprising: vinyl acids, vinyl acid ester, vinyl aryl compounds, vinyl acid anhydrides, vinyl amides, vinyl ethers, vinyl amines, vinyl aryl amines, vinyl nitriles, vinyl ketones, and derivatives thereof; hydroxyl-containing monomers and monomers which can be post-reacted to form hydroxyl groups; acid-containing or acid functional monomers; zwitterionic monomers; quaternised amino monomers, oligomeric monomers; and corresponding allyl monomers of the aforesaid vinyl monomers.
    • 本发明涉及通过加成聚合方法获得的支链共聚物及其用途及其组合物,其包含亲水性组分,所述聚合物包含:i)至少一种单官能单体的残基,每单分子含有一个可聚合双键,分子量为 小于1000道尔顿; ii)至少一种多官能单体的残基,每个分子包含至少两个可聚合双键,分子量小于1000道尔顿; 并且其中共聚物链的末端包含一个或多个链转移剂的残基; 来自终止反应的引发剂或末端基团; 其中; 单官能单体与多官能单体的摩尔比分别为50:1至2.5:1; 并且其中所述亲水性组分仅由至少1摩尔%的一种或多种单官能单体组成,所述单官能单体由在20℃的水中的溶解度为0.18W / W%的亲水性单体组成。 并且其中所述至少一种分子量小于1000道尔顿的单官能单体的残基选自:乙烯基酸,乙烯基酸酯,乙烯基芳基化合物,乙烯基酸酐,乙烯基酰胺,乙烯基醚,乙烯基胺 乙烯基芳基胺,乙烯基腈,乙烯基酮及其衍生物; 含羟基的单体和可以后反应形成羟基的单体; 含酸或酸官能单体; 两性离子单体; 季铵化氨基单体,低聚单体; 和上述乙烯基单体的相应的烯丙基单体。