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1. 发明申请

US20060278620A1 Method and apparatus for material processing 失效
标题翻译：材料加工方法和装置
公开(公告)号：US20060278620A1
公开(公告)日：2006-12-14
申请号：US11401114
申请日：2006-04-10
申请人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Ta-Chieh Huang , Michael Patena , Tim Burnham , Paul Coleman
发明人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Ta-Chieh Huang , Michael Patena , Tim Burnham , Paul Coleman
IPC分类号： B23K26/08 , B23K26/14
CPC分类号： B23K26/0884 , B23K26/032 , B23K26/12 , B23K26/123 , B23K26/128 , B23K26/1464
摘要： An apparatus processes a surface of an inhabitable structure. The apparatus includes a base unit adapted to provide energy waves to an interaction region, the energy waves removing material from the structure. The base unit includes an energy wave generator and a head coupled to the energy wave generator. The head is adapted to remove the material from the interaction region, thereby providing reduced disruption to activities within the structure. The apparatus further includes a manipulation system which includes an anchoring mechanism adapted to be releasably coupled to the structure and a positioning mechanism coupled to the anchoring mechanism and coupled to the head. The manipulation system is adapted to controllably adjust the position of the head relative to the structure. The apparatus further includes a controller electrically coupled to the base unit. The controller is adapted to transmit control signals to the base unit in response to user input.
摘要翻译：一种装置处理可居住结构的表面。该装置包括适于向相互作用区域提供能量波的基本单元，该能量波从该结构移除材料。基本单元包括能量波发生器和耦合到能量波发生器的头部。头适于从相互作用区域移除材料，从而减少对结构内的活动的破坏。该装置还包括操纵系统，该操纵系统包括适于可释放地联接到该结构的锚固机构，以及联接到该锚定机构并联接到头部的定位机构。操纵系统适于可控地调节头部相对于结构的位置。该装置还包括电耦合到基座单元的控制器。控制器适于响应于用户输入将控制信号发送到基本单元。

2. 发明申请

US20060196861A1 Manipulation apparatus for system that removes material from a surface of a structure 失效
标题翻译：用于从结构表面去除材料的系统的操纵装置
公开(公告)号：US20060196861A1
公开(公告)日：2006-09-07
申请号：US11401116
申请日：2006-04-10
申请人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Michael Patena , Tim Burnham , Paul Coleman
发明人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Michael Patena , Tim Burnham , Paul Coleman
IPC分类号： B23K26/08
CPC分类号： B23K26/032 , B23K26/10 , B23K26/12 , B23K26/123 , B23K26/128 , B23K26/16
摘要： A manipulation system controllably moves a head relative to a surface of an inhabitable structure for irradiating the surface with energy waves from the head. The manipulation system includes a positioning mechanism coupled to the head. The positioning mechanism includes a first-axis position system adapted to move the head along a first direction substantially parallel to the surface. The positioning mechanism further includes a second-axis position system coupled to the first-axis position system and adapted to move the head along a second direction substantially parallel to the surface. The manipulation system further includes an anchoring mechanism coupled to the positioning mechanism and releasably coupled to the structure.
摘要翻译：操纵系统可控制地相对于可居住结构的表面移动头部，以用头部的能量波照射表面。该操纵系统包括一个联接到头部的定位机构。定位机构包括适于沿着基本平行于表面的第一方向移动头部的第一轴位置系统。定位机构还包括耦合到第一轴位置系统并适于沿着基本上平行于表面的第二方向移动头部的第二轴位置系统。操纵系统还包括联接到定位机构并且可释放地联接到结构的锚定机构。

3. 发明申请

US20060144834A1 Containment plenum for laser irradiation and removal of material from a surface of a structure 审中-公开
标题翻译：用于激光照射和从结构表面去除材料的容纳气室
公开(公告)号：US20060144834A1
公开(公告)日：2006-07-06
申请号：US11363805
申请日：2006-02-28
申请人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips
发明人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips
IPC分类号： B23K26/14 , B23K26/08
CPC分类号： B23K26/032 , B23K26/035 , B23K26/042 , B23K26/12 , B23K26/123 , B23K26/127 , B23K26/128 , B23K26/16 , B23K26/206
摘要： A containment plenum is adapted to deliver laser light to an interaction region of a structure to remove material from the structure. The containment plenum includes a window substantially transparent to the laser light. The window transmits laser light towards the interaction region and provides a barrier to transport of particulate matter generated by interaction of the laser light and the structure. The containment plenum further includes a nozzle fluidly coupled to a source of compressed gas. The laser light and the compressed gas are transmitted through the nozzle towards the interaction region of the structure. The nozzle is either gas-cooled or liquid-cooled. The containment plenum further includes a resilient interface that resiliently contacts the structure and substantially surrounds the interaction region, thereby confining the material and removing the material from the interaction region.
摘要翻译：容纳气室适于将激光传送到结构的相互作用区域以从结构中去除材料。容纳气室包括对激光大致透明的窗口。该窗口将激光发射到相互作用区域，并且提供了通过激光和结构的相互作用产生的颗粒物质的输送的屏障。容纳气室还包括流体耦合到压缩气体源的喷嘴。激光和压缩气体通过喷嘴传递到结构的相互作用区域。喷嘴是气冷式或液冷式。容纳气室还包括弹性接触，弹性接触结构并且基本上围绕相互作用区域，从而限制材料并从相互作用区域移除材料。

4. 发明申请

US20070189347A1 Method and apparatus for material processing 失效
标题翻译：材料加工方法和装置
公开(公告)号：US20070189347A1
公开(公告)日：2007-08-16
申请号：US11653081
申请日：2007-01-12
申请人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Ta-Chieh Huang , Michael Patena , Tim Burnham , Paul Coleman
发明人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Ta-Chieh Huang , Michael Patena , Tim Burnham , Paul Coleman
IPC分类号： H01S3/00
CPC分类号： B23K26/0884 , B23K26/032 , B23K26/12 , B23K26/123 , B23K26/128 , B23K26/1464
摘要： An apparatus processes a surface of an inhabitable structure. The apparatus includes a laser base unit adapted to provide laser light to an interaction region, the laser light removing material from the structure. The laser base unit includes a laser generator and a laser head coupled to the laser generator. The laser head is adapted to remove the material from the interaction region, thereby providing reduced disruption to activities within the structure. The apparatus further includes an anchoring mechanism adapted to be releasably coupled to the structure and releasably coupled to the laser head. The apparatus further includes a controller electrically coupled to the laser base unit. The controller is adapted to transmit control signals to the laser base unit in response to user input.
摘要翻译：一种装置处理可居住结构的表面。该装置包括适于向相互作用区域提供激光的激光基座单元，该结构的激光去除材料。激光基座单元包括激光发生器和耦合到激光发生器的激光头。激光头适于从相互作用区域去除材料，从而减少对结构内活动的破坏。该装置还包括适于可释放地联接到结构并且可释放地联接到激光头的锚定机构。该装置还包括电耦合到激光基座单元的控制器。控制器适于响应于用户输入将控制信号发送到激光基座单元。

5. 发明申请

US20060144833A1 Laser head for irradiation and removal of material from a surface of a structure 失效
标题翻译：用于从结构表面照射和去除材料的激光头
公开(公告)号：US20060144833A1
公开(公告)日：2006-07-06
申请号：US11363647
申请日：2006-02-28
申请人： Paul Denney , Jay Eastman , Paul Fallara
发明人： Paul Denney , Jay Eastman , Paul Fallara
IPC分类号： B23K26/08
CPC分类号： B23K26/0884 , B23K26/032 , B23K26/0622 , B23K26/0643 , B23K26/08 , B23K26/12 , B23K26/123 , B23K26/127 , B23K26/128 , B23K26/1476 , B23K26/16 , B23K26/206 , B23K26/40 , B23K37/0217 , B23K2103/50
摘要： A laser head for irradiating an interaction region of a structure with laser light to remove material from the structure. The laser head includes a housing, an anchoring mechanism, and a connector coupled to the housing and optically coupled to a laser generator. The anchoring mechanism is reversably coupled to the housing and releasably affixed to the structure by vacuum pressure. The anchoring mechanism releasably holds the laser head at a selected position in relation to the structure. The connector transmits laser light from the laser generator. The laser head further includes a plurality of optical elements contained in the housing. The laser head further includes a containment plenum coupled to the housing. The containment plenum is optically coupled to the plurality of optical elements to receive the laser light. The containment plenum confines the material and removes the material from the interaction region resulting from irradiating the structure with the laser light.
摘要翻译：一种用于用激光照射结构的相互作用区域以从结构中去除材料的激光头。激光头包括壳体，锚定机构和连接到壳体并且光耦合到激光发生器的连接器。锚定机构可逆地联接到壳体并且通过真空压力可释放地固定到结构。锚定机构将激光头可释放地保持在相对于结构的选定位置。连接器从激光发生器传输激光。激光头还包括容纳在壳体中的多个光学元件。激光头还包括联接到壳体的容纳室。容纳气室与多个光学元件光学耦合以接收激光。容纳气室将材料限制并从激光照射结构所产生的相互作用区域中去除材料。

6. 发明申请

US20060062265A1 Method and apparatus for material processing 失效
标题翻译：材料加工方法和装置
公开(公告)号：US20060062265A1
公开(公告)日：2006-03-23
申请号：US11205290
申请日：2005-08-16
申请人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Ta-Chieh Huang , Michael Patena , Tim Burnham , Paul Coleman
发明人： Paul Denney , Jay Eastman , Paul Fallara , Andrew Joseph , John Phillips , Ta-Chieh Huang , Michael Patena , Tim Burnham , Paul Coleman
IPC分类号： H01S3/00
CPC分类号： B23K26/12 , B23K26/032 , B23K26/0884 , B23K26/123 , B23K26/127 , B23K26/142 , B23K26/1464 , B23K26/1476
摘要： An apparatus processes a surface of an inhabitable structure. The apparatus includes a laser base unit which irradiates an interaction region with laser light, the laser light removing material from the structure. The laser base unit includes a laser generator and a laser head coupled to the laser generator. The laser head includes a containment plenum which confines and removes material from the interaction region. The containment plenum includes a rubber seal which contacts the structure and which substantially surrounds the interaction region, thereby facilitating confinement and removal of material from the interaction region, and providing reduced disruption to activities within the structure. The apparatus further includes an anchoring mechanism releasably coupled to the structure and releasably coupled to the laser head. The apparatus further includes a controller electrically coupled to the laser base unit. The controller transmits control signals to the laser base unit in response to user input.
摘要翻译：一种装置处理可居住结构的表面。该装置包括：用激光照射相互作用区域的激光基座单元，该结构中的激光去除材料。激光基座单元包括激光发生器和耦合到激光发生器的激光头。激光头包括限制并从相互作用区域去除材料的容纳气室。容纳气室包括橡胶密封件，其接触结构并且基本上围绕相互作用区域，从而有助于材料从相互作用区域的限制和移除，并且减少对结构内活动的破坏。该装置还包括可释放地联接到结构并且可释放地联接到激光头的锚定机构。该装置还包括电耦合到激光基座单元的控制器。控制器响应于用户输入将控制信号发送到激光基座单元。

7. 发明申请

US20050040150A1 Laser head for irradiation and removal of material from a surface of a structure 失效
标题翻译：用于从结构表面照射和去除材料的激光头
公开(公告)号：US20050040150A1
公开(公告)日：2005-02-24
申请号：US10690833
申请日：2003-10-22
申请人： Paul Denney , Jay Eastman , Paul Fallara
发明人： Paul Denney , Jay Eastman , Paul Fallara
IPC分类号： B23K26/08 , B23K26/10 , B23K26/12 , B23K26/16 , B23K26/14
CPC分类号： B23K26/0884 , B23K26/032 , B23K26/0622 , B23K26/0643 , B23K26/08 , B23K26/12 , B23K26/123 , B23K26/127 , B23K26/128 , B23K26/1476 , B23K26/16 , B23K26/206 , B23K26/40 , B23K37/0217 , B23K2103/50
摘要： A laser head is adapted to irradiate an interaction region of an inhabitable structure with laser light to remove material from the structure. The laser head includes a housing. The laser head further includes a connector coupled to the housing and optically coupled to a laser generator. The connector is adapted to transmit laser light from the laser generator. The laser head further includes at least one optical element contained in the housing and optically coupled to the connector. The optical element is adapted to receive laser light from the connector. The laser head further includes a containment plenum coupled to the housing. The containment plenum is optically coupled to the optical element to receive the laser light from the optical element. The containment plenum is adapted to confine the material and remove the material from the interaction region resulting from irradiating the structure with the laser light.
摘要翻译：激光头适于用激光照射可居住结构的相互作用区域以从结构中去除材料。激光头包括壳体。激光头还包括连接到壳体并光学耦合到激光发生器的连接器。连接器适于传输来自激光发生器的激光。激光头还包括容纳在壳体中并光学耦合到连接器的至少一个光学元件。光学元件适于接收来自连接器的激光。激光头还包括联接到壳体的容纳室。容纳气室光耦合到光学元件以接收来自光学元件的激光。容纳气室适于限制材料，并从由激光照射结构而产生的相互作用区域中去除材料。

8. 发明申请

US20080067331A1 METHOD AND APPARATUS FOR DETECTING EMBEDDED MATERIAL WITHIN AN INTERACTION REGION OF A STRUCTURE 失效
标题翻译：用于检测结构相互作用区域中的嵌入材料的方法和装置
公开(公告)号：US20080067331A1
公开(公告)日：2008-03-20
申请号：US11861184
申请日：2007-09-25
申请人： Paul Denney , Jay Eastman , Ta-Chieh Huang
发明人： Paul Denney , Jay Eastman , Ta-Chieh Huang
IPC分类号： G01J5/08
CPC分类号： B23K26/032 , B23K26/03 , B23K26/034 , B23K26/043 , B23K26/12 , B23K26/123 , B23K26/128 , B23K26/142 , B23K26/16 , G01J3/02 , G01J3/0218 , G01J3/0291 , G01J3/28
摘要： A system and method processes a structure comprising embedded material. The system includes a laser adapted to generate light and to irradiate an interaction region of the structure. The system further includes an optical system adapted to receive light from the interaction region and to generate a detection signal indicative of the presence of embedded material in the interaction region. The system further includes a controller operatively coupled to the laser and the optical system. The controller is adapted to receive the detection signal and to be responsive to the detection signal by selectively adjusting the laser.
摘要翻译：系统和方法处理包括嵌入材料的结构。该系统包括适于产生光并照射结构的相互作用区域的激光器。该系统还包括适于接收来自相互作用区域的光并且产生指示在相互作用区域中存在嵌入材料的检测信号的光学系统。该系统还包括可操作地耦合到激光器和光学系统的控制器。控制器适于接收检测信号，并通过选择性调节激光来响应检测信号。

9. 发明申请

US20070070497A1 System and method for enhancing confocal reflectance images of tissue specimens 审中-公开
标题翻译：用于增强组织标本的共焦反射图像的系统和方法
公开(公告)号：US20070070497A1
公开(公告)日：2007-03-29
申请号：US11601203
申请日：2006-11-17
申请人： Jay Eastman , Milind Rajadhyaksha , James Zavislan
发明人： Jay Eastman , Milind Rajadhyaksha , James Zavislan
IPC分类号： G02B21/06
CPC分类号： G02B21/0068 , A61K49/001 , G01N33/5743
摘要： A system using cross polarization effects and an enhancement agent having citric or other similar alpha hydroxy acid to enhance confocal microscope reflectance images and particularly images of the nuclei of BCCs (basal cell carcinomas) and SCCs (squamous cell carcinomas) in the confocal reflectance images of excised tumor slices obtained during Mohs surgery by illuminating the tissue being imaged (a tumor slice) using polarized light. The reflected illumination is passed to a polarization analyzer, which passes the polarization component which is crossed with respect to the polarization of the illuminating light. The light from the analyzer is passed through the confocal aperture and detected. The section of the tissue either at the surface or within the tissue is scanned and the reflectance image is produced with enhanced visualization of the cellular or nuclear structure thereof thereby enabling determination of the extent of the tumor (cancerous cells) in the section. A method is also provided using the system for diagnosing cancerous cells in skin tissue.
摘要翻译：使用交叉极化效应的系统和具有柠檬酸或其它类似α羟基酸的增强剂来增强共聚焦显微镜反射图像，特别是BCC（基底细胞癌）和SCC（鳞状细胞癌）的核的图像在共聚焦反射图像中通过使用偏振光照射被成像的组织（肿瘤切片）在Mohs手术期间获得的切除的肿瘤切片。反射的照明被传递到偏振分析器，偏振分析器使相对于照明光的偏振交叉的偏振分量通过。来自分析仪的光通过共焦孔并检测。扫描在表面或组织内的组织的部分，并且通过细胞或核结构的增强的可视化产生反射图像，从而能够确定该部分中肿瘤（癌细胞）的程度。还提供了一种用于诊断皮肤组织中的癌细胞的系统的方法。

10. 发明申请

US20050101871A1 Microscopic imaging apparatus and method 有权
标题翻译：显微成像设备及方法
公开(公告)号：US20050101871A1
公开(公告)日：2005-05-12
申请号：US11013099
申请日：2004-12-15
申请人： James Zavislan , Jay Eastman
发明人： James Zavislan , Jay Eastman
IPC分类号： A61B5/00 , A61B5/103 , A61B6/00
CPC分类号： A61B5/444 , A61B5/0059 , A61B5/0064 , A61B5/0068 , A61B2562/146
摘要： A handheld confocal imaging system for in vivo observation of dermal and subdermal tissue allows diagnosis of conditions substantially beneath the surface of the skin. A confocal head has optics which scan the tissue so as to provide images of vertical sections of the tissue. Both two and three dimensional imaging may be provided for diagnosis and location of basal cell carcinomas and melanomas, and so as to enable visualization of tumor borders prior to excision.
摘要翻译：用于体内观察皮肤和皮下组织的手持共聚焦成像系统允许诊断基本上在皮肤表面下方的状况。共焦头具有扫描组织以便提供组织的垂直部分的图像的光学元件。可以提供二维和三维成像用于诊断和定位基底细胞癌和黑素瘤，并且可以在切除前使肿瘤边界可视化。

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