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1. 发明授权

US5635516A (Thia) cycloalkyl[B]indole compounds as anti-inflammatory agents 失效
标题翻译：（Thia）环烷基[B]吲哚化合物作为抗炎剂
公开(公告)号：US5635516A
公开(公告)日：1997-06-03
申请号：US495226
申请日：1995-06-27
申请人： Paul Caubere , Brigitte Jamart-Gregoire , Catherine Caubere , Dominique Manechez , Pierre Renard , Gerard Adam , Catherine Nguyen
发明人： Paul Caubere , Brigitte Jamart-Gregoire , Catherine Caubere , Dominique Manechez , Pierre Renard , Gerard Adam , Catherine Nguyen
IPC分类号： A61K31/40 , A61K31/403 , A61K31/41 , A61K31/415 , A61K31/42 , A61K31/425 , A61K31/44 , A61K31/4427 , A61K31/4433 , A61K31/47 , A61P1/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/08 , A61P13/02 , A61P15/00 , A61P17/00 , A61P29/00 , A61P37/08 , A61P43/00 , C07D209/94 , C07D401/12 , C07D409/12 , C07D417/12 , C07D495/04 , C07D215/12
CPC分类号： C07D401/12 , C07D209/94 , C07D495/04
摘要： A compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description.
摘要翻译：选自式（I）的化合物：其中R 1，R 2，R 3和A如说明书中所定义。

2. 发明申请

US20050010175A1 Piston assembly for syringe 审中-公开
标题翻译：活塞组件用于注射器
公开(公告)号：US20050010175A1
公开(公告)日：2005-01-13
申请号：US10788818
申请日：2004-02-27
申请人： Daniel Beedon , Erin Lundtveit , Edwin Chim , Craig Sandford , Derek Walsh , Jennifer Ikeda , Carol Johns , Catherine Nguyen , James Rose , Atif Yardimci
发明人： Daniel Beedon , Erin Lundtveit , Edwin Chim , Craig Sandford , Derek Walsh , Jennifer Ikeda , Carol Johns , Catherine Nguyen , James Rose , Atif Yardimci
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/31513 , A61M5/31515
摘要： A piston assembly (10) for a flowable materials container having a barrel (14) defining a fluid containing chamber (16). The barrel (14) is made of a body of a cyclic olefin containing polymer or a bridged polycyclic olefin containing polymer. An elastomeric piston (24) is slidably attached to the barrel (14) and provides a seal of the chamber. The piston (24) has a parylene coating on an outer surface thereof to reduce the necessary break away force. A plunger (22) is also provided and has a second mating member (42) removably connecting the plunger to a first mating member (44) of the piston. The first mating member (44) has a series of threads having a major diameter and a minor diameter, and the second mating member (42) has a series of threads having a major diameter and a minor diameter. The major and minor diameters of the second mating members (42) is appreciably smaller than the major and minor diameters of the other of the first mating member (44) to provide ease of connection.
摘要翻译：一种用于可流动材料容器的活塞组件（10），其具有限定流体容纳室（16）的桶（14）。桶（14）由含环烯烃的聚合物或含桥连多环烯烃的聚合物的主体制成。弹性体活塞（24）可滑动地附接到筒体（14）并提供腔室的密封。活塞（24）在其外表面上具有聚对二甲苯涂层以减少必要的脱离力。还设置有柱塞（22），并且具有将活塞可移除地连接到活塞的第一配合构件（44）的第二配合构件（42）。第一配合构件（44）具有一系列具有大直径和小直径的螺纹，并且第二配合构件（42）具有一系列具有大直径和小直径的螺纹。第二配合构件（42）的主要和次要尺寸明显小于第一配合构件（44）中另一个的主要和次要直径，以提供易于连接。

3. 发明授权

US5634035A HDLC hardware engine and shared memory interface with access request/acknowledgement control and addressing scheme 失效
标题翻译： HDLC硬件引擎和具有访问请求/确认控制和寻址方案的共享存储器接口
公开(公告)号：US5634035A
公开(公告)日：1997-05-27
申请号：US528754
申请日：1995-09-15
申请人： Florin Gheorghiu , Catherine Nguyen
发明人： Florin Gheorghiu , Catherine Nguyen
IPC分类号： G06F13/38 , H04L12/56 , H04L29/06 , H04L29/08 , G06F12/00 , G06F13/00
CPC分类号： H04L29/06 , G06F13/385 , H04L49/90 , H04L69/324
摘要： By handling initial processing of HDLC frames, an HDLC engine can free up a server microprocessor that would otherwise be tasked to respond to incoming frames. Sharing a memory with the microprocessor, the engine periodically accesses an address status table in the memory to retrieve data in order to process received frames based on the status of the frame address.
摘要翻译：通过处理HDLC帧的初始处理，HDLC引擎可以释放服务器微处理器，否则这些服务器微处理器将负责响应输入帧。与微处理器共享存储器，引擎周期性地访问存储器中的地址状态表以检索数据，以便基于帧地址的状态来处理接收到的帧。

4. 发明申请

US20130201199A1 INITIATION OF ACTIONS BY A PORTABLE COMPUTING DEVICE FROM A LOCKED STATE 有权
标题翻译：通过便携式计算设备从锁定状态启动行动
公开(公告)号：US20130201199A1
公开(公告)日：2013-08-08
申请号：US13366369
申请日：2012-02-06
申请人： Catherine Nguyen , Nathan J. Fortin , Rachid El Guerrab , Kye-Wan Sung , Matthew Oursbourn , Timothy R. Richards , Ogi Boras , Ryan W. Enslow , Joshua M. VanHeirseele
发明人： Catherine Nguyen , Nathan J. Fortin , Rachid El Guerrab , Kye-Wan Sung , Matthew Oursbourn , Timothy R. Richards , Ogi Boras , Ryan W. Enslow , Joshua M. VanHeirseele
IPC分类号： G09G5/02 , G06F3/041
CPC分类号： G06F3/0488 , G06F3/0481 , G06F3/0482 , G06F3/04842 , G06F3/04845 , G06F3/04883 , G06F2203/04801 , G09G2320/0686 , G09G2340/045 , G09G2354/00
摘要： A method and apparatus for performing an action while a portable computing device is in a locked state is disclosed. An unlock image is displayed in a first region of a touch-sensitive display. Responsive to detecting contact with the touch-sensitive display at the first region, an action image is displayed in a second region of the touch-sensitive display. While the unlock image remains stationary at the first region, movement of the contact with the touch-sensitive display is detected and a direction of movement of the contact is determined. Responsive to determining the direction of movement of the contact is towards the action image, the action image is visually modified to distinguish it from the unlock image. Responsive to the contact with the touch-sensitive display reaching the second region, an action associated with the action image is performed.
摘要翻译：公开了一种在便携式计算设备处于锁定状态时执行动作的方法和装置。在触敏显示器的第一区域中显示解锁图像。响应于检测与第一区域处的触敏显示器的接触，在触敏显示器的第二区域中显示动作图像。当解锁图像在第一区域保持静止时，检测到与触敏显示器的触点的移动，并且确定触点的移动方向。响应于确定联系人的移动方向是针对动作图像，动作图像被视觉上修改以将其与解锁图像区分开。响应于与到达第二区域的触敏显示器的接触，执行与动作图像相关联的动作。

5. 发明申请

US20130079234A1 GENE EXPRESSION PROFILING OF PRIMARY BREAST CARCINOMAS USING ARRAYS OF CANDIDATE GENES 审中-公开
标题翻译：使用候选基因阵列的原始乳腺癌基因表达谱
公开(公告)号：US20130079234A1
公开(公告)日：2013-03-28
申请号：US13116518
申请日：2011-05-26
申请人： Francois Bertucci , Rémi Houlgatte , Daniel Birnbaum , Catherine Nguyen , Patrice Viens , Vincent Fert
发明人： Francois Bertucci , Rémi Houlgatte , Daniel Birnbaum , Catherine Nguyen , Patrice Viens , Vincent Fert
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： A method for predicting the sensitivity of tumor cells to an anthracycline-based chemotherapy includes determining the differential expression level of a MYBL2 gene in tumors cells. A polynucleotide library is useful to predict the sensitivity of tumor cells to an anthracycline-based chemotherapy and includes a pool of polynucleotide sequences or subsequences thereof wherein the sequences or subsequences correspond substantially to any of the polynucleotide sequences SEQ ID No: 308, SEQ ID No: 309 and/or SEQ ID No: 310 or the complements thereof.
摘要翻译：用于预测肿瘤细胞对蒽环类化疗的敏感性的方法包括测定肿瘤细胞中MYBL2基因的差异表达水平。多核苷酸文库可用于预测肿瘤细胞对基于蒽环霉素的化疗的敏感性，并且包括多核苷酸序列或其子序列库，其中所述序列或子序列基本上对应于任何多核苷酸序列SEQ ID No：308，SEQ ID No ：309和/或SEQ ID No：310或其互补序列。

6. 发明申请

US20110086765A1 GENE EXPRESSION PROFILING OF PRIMARY BREAST CARCINOMAS USING ARRAYS OF CANDIDATE GENES 审中-公开
标题翻译：使用候选基因阵列的原始乳腺癌基因表达谱
公开(公告)号：US20110086765A1
公开(公告)日：2011-04-14
申请号：US12903594
申请日：2010-10-13
申请人： Francois Bertucci , Rémi Houlgatte , Daniel Birnbaum , Catherine Nguyen , Patrice Viens , Vincent Fert
发明人： Francois Bertucci , Rémi Houlgatte , Daniel Birnbaum , Catherine Nguyen , Patrice Viens , Vincent Fert
IPC分类号： C40B30/00 , C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： Method for molecular characterization of a carcinoma including: (i) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a first group determining expression level of the polynucleotide from the first group to differentiate a tumor in which a lymph node has been invaded by a tumor cell from a tumor in which a lymph node has not been invaded by a tumor cell; (ii) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a second group determining expression level of the polynucleotide from the second group to distinguish tumors sensitive to anthracycline from tumors insensitive to anthracycline; (iii) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a third group determining expression levels of the polynucleotide from the third group to classify good and poor prognosis primary breast tumors.
摘要翻译：用于癌症的分子表征的方法，包括：（i）在与肿瘤细胞相对应的肿瘤细胞中检测至少一种选自第一组的多核苷酸，所述第一组确定来自第一组的多核苷酸的表达水平以区分其中淋巴结具有的肿瘤被肿瘤细胞侵入，其中淋巴结未被肿瘤细胞侵袭的肿瘤; （ii）在对应于乳腺肿瘤细胞的肿瘤细胞中检测至少一种选自第二组的多核苷酸，其确定来自第二组的多核苷酸的表达水平，以将对蒽环霉素敏感的肿瘤与对蒽环霉素不敏感的肿瘤区分开; （iii）在相应于乳腺肿瘤细胞的肿瘤细胞中检测至少一种选自第三组的多核苷酸，其确定来自第三组的多核苷酸的表达水平以分类良好和不良预后的原发性乳腺肿瘤。

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