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1. 发明申请

US20100144667A1 METHODS FOR FUCOIDAN PURIFICATION FROM SEA WEED EXTRACTS 有权
标题翻译：从海洋萃取物中获取富马酸的方法
公开(公告)号：US20100144667A1
公开(公告)日：2010-06-10
申请号：US12449712
申请日：2008-02-01
申请人： Patrick N. Shaklee , Jennifer Bahr-Davidson , Srinivasa Prasad , Kirk Johnson
发明人： Patrick N. Shaklee , Jennifer Bahr-Davidson , Srinivasa Prasad , Kirk Johnson
IPC分类号： A61K31/715 , C07H1/06
CPC分类号： C08B37/0063 , A61K31/726 , A61K31/737 , A61K36/03 , A61K45/06 , C08B37/0036
摘要： Methods for purifying fucoidan in extracts from brown seaweed are disclosed. In particular, methods of purifying fucoidan in the extract to remove heavy metal ions, bacterial and endotoxin contaminants, and other impurities are disclosed. The methods include the use of a chelating agent, selective precipitation, and filtration.
摘要翻译：公开了褐藻提取物中岩藻多糖的纯化方法。特别地，公开了提取物中去除重金属离子，细菌和内毒素污染物以及其它杂质的岩藻依聚糖的纯化方法。所述方法包括使用螯合剂，选择性沉淀和过滤。

2. 发明授权

US08748595B2 Methods for fucoidan purification from sea weed extracts 有权
标题翻译：海藻提取物中岩藻依聚糖纯化方法
公开(公告)号：US08748595B2
公开(公告)日：2014-06-10
申请号：US12449712
申请日：2008-02-01
申请人： Patrick N. Shaklee , Jennifer Bahr-Davidson , Srinivasa Prasad , Kirk Johnson
发明人： Patrick N. Shaklee , Jennifer Bahr-Davidson , Srinivasa Prasad , Kirk Johnson
IPC分类号： C07H15/04 , A61K31/715
CPC分类号： C08B37/0063 , A61K31/726 , A61K31/737 , A61K36/03 , A61K45/06 , C08B37/0036
摘要： Methods for purifying fucoidan in extracts from brown seaweed are disclosed. In particular, methods of purifying fucoidan in the extract to remove heavy metal ions, bacterial and endotoxin contaminants, and other impurities are disclosed. The methods include the use of a chelating agent, selective precipitation, and filtration.
摘要翻译：公开了褐藻提取物中岩藻多糖的纯化方法。特别地，公开了提取物中去除重金属离子，细菌和内毒素污染物以及其它杂质的岩藻依聚糖的纯化方法。所述方法包括使用螯合剂，选择性沉淀和过滤。

3. 发明授权

US08527639B1 Content server selection for accessing content in a content distribution network 有权
标题翻译：用于访问内容分发网络中的内容的内容服务器选择
公开(公告)号：US08527639B1
公开(公告)日：2013-09-03
申请号：US09642165
申请日：2000-08-18
申请人： Barbara Liskov , James O'Toole , M. Frans Kaashoek , Kirk Johnson
发明人： Barbara Liskov , James O'Toole , M. Frans Kaashoek , Kirk Johnson
IPC分类号： G06F15/173 , G06F15/16
CPC分类号： H04L67/1004 , H04L67/101 , H04L67/1021
摘要： Content servers are directed to send messages to network nodes which are used to obtain IP addresses and to receive responses from the network nodes. The responses provide network service information. The content servers collect data based on the responses and feed the data to a routing server. Based on the data fed to the routing server, respective choices of content servers are selected and provided to the network nodes to respond to clients requesting content server addresses from the network nodes.
摘要翻译：内容服务器旨在向用于获取IP地址并从网络节点接收响应的网络节点发送消息。响应提供网络服务信息。内容服务器根据响应收集数据，并将数据提供给路由服务器。基于馈送到路由服务器的数据，选择内容服务器的各个选择并提供给网络节点以响应来自网络节点的请求内容服务器地址的客户端。

4. 发明授权

US08313909B2 Herbicide tolerant rice plants and methods for identifying same 有权
标题翻译：除草剂耐受性水稻植物及其鉴定方法
公开(公告)号：US08313909B2
公开(公告)日：2012-11-20
申请号：US13037573
申请日：2011-03-01
申请人： Marc De Beuckeleer , Kirk Johnson , Frank Michiels
发明人： Marc De Beuckeleer , Kirk Johnson , Frank Michiels
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04
CPC分类号： C12N15/8277 , A01H5/10
摘要： The invention provides specific transgenic rice plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the rice genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological samples.
摘要翻译：本发明提供特定的转基因水稻植物，植物材料和种子，其特征在于这些产品在水稻基因组中的特定位置处具有特异性转化事件。还提供了允许快速且明确地识别生物样品中的事件的工具。

5. 发明授权

US07886023B1 Method and apparatus for a minimalist approach to implementing server selection 有权
标题翻译：实现服务器选择的简约方法和方法
公开(公告)号：US07886023B1
公开(公告)日：2011-02-08
申请号：US09824527
申请日：2001-04-02
申请人： Kirk Johnson
发明人： Kirk Johnson
IPC分类号： G06F15/16
CPC分类号： H04L67/1002 , H04L67/1019 , H04L67/1025
摘要： Server selection is optimized using randomness, feedback, and fanout. A central server maintains a vector of server selection probabilities and provides a subset of candidate servers from the vector for the client in response to receiving from a client a request for a server address to provide substantive service. An interrogating node (i.e., the client or DNS proxy) probes the candidate servers and selects a best server based on at least one criterion. The client accesses the selected server for the substantive data, and the selected server updates a counter used to keep track of the number of times the server is selected. The servers feedback the number of times selected to the central server, which, in turn, updates weightings in the vector of server selection probabilities.
摘要翻译：服务器选择使用随机性，反馈和扇出优化。中央服务器维护服务器选择概率的向量，并响应于从客户端接收到服务器地址提供实质性服务的请求，向客户端向量提供候选服务器的子集。询问节点（即，客户端或DNS代理）探测候选服务器并基于至少一个标准选择最佳服务器。客户端访问所选服务器的实体数据，所选择的服务器更新用于跟踪服务器被选择次数的计数器。服务器将选择的次数反馈给中央服务器，这反过来更新了服务器选择概率向量中的权重。

6. 发明申请

US20060289772A1 Visible light and IR combined image camera with a laser pointer 有权
公开(公告)号：US20060289772A1
公开(公告)日：2006-12-28
申请号：US11294752
申请日：2005-12-05
申请人： Kirk Johnson , Thomas McManus , John Pratten
发明人： Kirk Johnson , Thomas McManus , John Pratten
IPC分类号： G01T1/24
CPC分类号： G01C3/08 , G01J5/025 , G01J5/0265 , G01J5/0295 , G01J5/0859 , G01J5/089 , G01J5/0896 , H01L27/14618 , H01L27/14625 , H01L2924/0002 , H04N5/2254 , H04N5/2258 , H04N5/23212 , H04N5/23293 , H04N5/33 , H04N5/332 , H01L2924/00
摘要： Methods and apparatuses of registering on a camera display separate fields of view of a visible light camera module and an infrared camera module by focusing the IR camera module. The fields of view can be displayed in several display modes including 1) full screen visible, infrared and/or blended, 2) picture-in-a-picture such as partial infrared image in a full screen visible image, and 3) infrared color alarms in visible-light images.

7. 发明申请

US20060086254A1 Liquid absorbing filter assembly and system 有权
标题翻译：液体吸收过滤器组件和系统
公开(公告)号：US20060086254A1
公开(公告)日：2006-04-27
申请号：US11266864
申请日：2005-11-04
申请人： Brian Fudge , Patrick Tuxbury , Kirk Johnson
发明人： Brian Fudge , Patrick Tuxbury , Kirk Johnson
IPC分类号： B01D46/00
CPC分类号： A61M16/085 , A61B5/097 , A61M16/1065 , A61M2230/432
摘要： A filter assembly for use in sidestream gas sampling assembly. The filter assembly of the present invention includes a hydrophilic The filter further includes a hydrophobic member positioned downstream of the hydrophilic liner. The hydrophobic disk acts as a second line of defense against moisture reaching the sensing mechanism member that is constructed from a porous material and is situated such that gas entering the filter assembly passes through at least a portion the hydrophilic member. In a further embodiment, the filter includes a hydrophobic member positioned downstream of the hydrophilic member. The hydrophobic member acts as a second line of defense against moisture reaching the sensing mechanism in the gas sampling assembly.
摘要翻译：用于侧流气体采样组件的过滤器组件。本发明的过滤器组件包括亲水性。过滤器还包括位于亲水衬垫下游的疏水构件。疏水盘作为防止湿气到达由多孔材料构成的感测机构构件的第二防线，并且位于使得进入过滤器组件的气体通过至少一部分亲水构件。在另一实施例中，过滤器包括位于亲水构件下游的疏水构件。疏水构件作为防止气体到达气体采样组件中的感测机构的第二防线。

8. 发明申请

US20050173841A1 System and method for vacuum bag fabrication 有权
标题翻译：真空袋制造系统和方法
公开(公告)号：US20050173841A1
公开(公告)日：2005-08-11
申请号：US11000356
申请日：2004-11-30
申请人： David Ciambrone , Kirk Johnson , Hossein Ahmad
发明人： David Ciambrone , Kirk Johnson , Hossein Ahmad
IPC分类号： B29C70/00
CPC分类号： B32B37/1018 , B32B2309/68
摘要： A system and method for vacuum bag assembly fabrication via the vacuum bag method which reduces the amount of trapped air. The inventive system includes a chamber adapted to contain a vacuum bag and first and second evacuating mechanisms. The first evacuating mechanism serves to evacuate the bag and vent to atmosphere. The second evacuating mechanism serves to evacuate and vent the chamber to atmosphere. Thus, generally, the inventive method includes the steps of placing a vacuum bag lay up in an air tight chamber; and evacuating the vacuum bag lay up and the air tight chamber at the same time. In practice, the assembly would consist of at least two components and a heat curable composition. The components can be parts to be bonded together or layers of cloth to be made into a laminate. In this case, the heat curable composition would be a catalyzed adhesive or resin.
摘要翻译：一种通过真空袋方法制造真空袋组件的系统和方法，其减少了被捕获的空气的量。本发明的系统包括适于容纳真空袋和第一和第二抽空机构的室。第一抽空机构用于抽出袋并排放到大气中。第二抽空机构用于抽空并将该室排放到大气中。因此，通常，本发明的方法包括将真空袋放置在气密室中的步骤; 同时抽空真空袋和气密室。在实践中，组件将由至少两个组分和可热固化组合物组成。这些部件可以是要被粘合在一起的部件或要制成层压板的布层。在这种情况下，可热固化的组合物将是催化的粘合剂或树脂。

9. 发明授权

US06242414B1 Regulation of cytokine synthesis and release 失效
标题翻译：调节细胞因子的合成和释放
公开(公告)号：US06242414B1
公开(公告)日：2001-06-05
申请号：US08483459
申请日：1995-06-07
申请人： Kirk Johnson , Abla A. Creasey , Lucien A. Aarden
发明人： Kirk Johnson , Abla A. Creasey , Lucien A. Aarden
IPC分类号： A61K3800
CPC分类号： A61K38/57
摘要： Methods of treatment and prevention of diseases associated with release of neutrophil elastase and IL-8 by administration of TFPI, and analogs of TFPI are disclosed. Methods of determining efficacy of treatment with TFPI, patient's responsiveness to treatment with TFPI and the ultimate determination of patient prognosis are also disclosed.
摘要翻译：公开了通过施用TFPI来治疗和预防与释放嗜中性粒细胞弹性蛋白酶和IL-8相关的疾病的方法和TFPI的类似物。还公开了确定TFPI治疗效果的方法，患者对TFPI治疗的反应性和患者预后的最终测定。

10. 发明授权

US09808255B2 Embolic coil detachment mechanism with flexible distal member, resistive electrical heating element and shape memory polymer element 有权
公开(公告)号：US09808255B2
公开(公告)日：2017-11-07
申请号：US13436376
申请日：2012-03-30
申请人： Juan A. Lorenzo , Kirk Johnson
发明人： Juan A. Lorenzo , Kirk Johnson
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/1214 , A61B2017/00867 , A61B2017/00871 , A61B2017/00951 , A61B2017/1205 , A61B2017/12054 , A61B2017/12068 , A61B2017/12077
摘要： An embolic coil detachment system includes an elongated, flexible shape memory polymer tube having an inner wall surface defining an interior lumen. A distal portion of the shape memory polymer tube has an enlarged and reduced diameter configurations. An embolic coil is releasably mounted to the shape memory polymer tube by a headpiece releasably attached within a distal portion of the shape memory polymer tube. A resistive heating element disposed longitudinally along and in immediate contact with the inner wall surface of the distal tubular wall of the shape memory polymer tube provides direct, even heating to release the headpiece and embolic coil attached thereto when the resistive heating element is energized.

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