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    • 7. 发明申请
    • 1,3-Oxathiolane-2-thione compounds
    • 1,3-氧硫杂环戊烷-2-硫酮化合物
    • US20060293280A1
    • 2006-12-28
    • US11354390
    • 2006-02-15
    • Kazuya UenishiAtsushi SudoHiroshi MorikawaTakeshi EndoOlaf LammerschopThomas HuverPavel Gentschev
    • Kazuya UenishiAtsushi SudoHiroshi MorikawaTakeshi EndoOlaf LammerschopThomas HuverPavel Gentschev
    • A61K31/695C07F7/02
    • C08G77/28C07F7/1804C08G75/28
    • The present invention relates to 1,3-oxathiolane-2-thione compounds of the general formula (I): wherein R1 and R2 are the same or different, each of which denotes a straight-chain or branched alkoxy residue with 1 to 6 carbon atoms or an aryloxy or aralkyloxy residue, R3 is different or the same as R1 or R2 or an aliphatic residue, an amino residue, a halogen residue, an aromatic or heteroaromatic residue, or an araliphatic or heteroaraliphatic residue, R4 is a bridging group selected from the groups consisting of aliphatic, heteroaliphatic, araliphatic, heteroaraliphatic, aromatic and heteroaromatic groups and R5 is hydrogen, an aliphatic, heteroaliphatic, araliphatic, heteroaraliphatic, aromatic, heteroaromatic, cycloaliphatic or heterocycloaliphatic group or R4 and R5 form a cycloaliphatic, cycloheteroaliphatic, aromatic or heteroaromatic residue, which is optionally substituted with an aliphatic, heteroaliphatic residue serving as a bridging group to the silicon atom and X and Y are different and selected from oxygen and sulfur and mixtures of such compounds.
    • 本发明涉及通式(I)的1,3-氧硫杂环戊烷-2-硫酮化合物:其中R 1和R 2各自相同或不同,各自相同或不同, 表示具有1至6个碳原子的直链或支链烷氧基残基或芳氧基或芳烷氧基残基,R 3不同于或不同于R 1或R 2 脂族残基,氨基残基,卤素残基,芳香族或杂芳族残基或芳脂族或杂脂族残基,R 4是选自以下的桥连基团: 由脂族,杂脂族,芳脂族,杂脂肪族,芳族和杂芳族基团组成的基团,R 5是氢,脂族,杂脂族,芳脂族,杂脂族,芳族,杂芳族,脂环族或杂脂族基团或R 4和R 5形成脂环族,杂脂族,芳族或杂芳族残基,其任选被 n个作为与硅原子的桥连基团的脂族,杂脂族残基,X和Y不同,选自氧和硫以及这些化合物的混合物。