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1. 发明授权

US4557753A Herbicidal 4-benzoyl-1-methyl-5-phenylalkoxy pyrazoles 失效
标题翻译：除草4-苯甲酰基-1-甲基-5-苯基烷氧基吡唑
公开(公告)号：US4557753A
公开(公告)日：1985-12-10
申请号：US485832
申请日：1983-04-18
申请人： Norio Tanaka , Masakazu Taniguchi , Masatoshi Baba , Takashi Ikai , Tsutomu Nawamaki , Masaji Matsunaga
发明人： Norio Tanaka , Masakazu Taniguchi , Masatoshi Baba , Takashi Ikai , Tsutomu Nawamaki , Masaji Matsunaga
IPC分类号： A01N43/56 , C07D231/16 , C07D231/20 , C07D405/12
CPC分类号： C07D405/12 , A01N43/56 , C07D231/16 , C07D231/20
摘要： Pyrazole derivatives, preparations thereof, selective herbicidal compositions containing said derivatives and the use of said derivatives are provided. The pyrazole derivatives having selective herbicidal activity are represented by the formula I: ##STR1## wherein, A denotes a straight or branched lower alkylene or lower alkylidene group; X denotes a halogen atom, nitro group, a lower alkyl group, a lower haloalkyl group, a lower alkoxy group, a lower haloalkoxy group, a lower alkenyl group, phenyl group, cyano group, phenoxy group, a lower alkoxycarbonyl group, an aliphatic or aromatic acyl group, methanesulfonyloxy group or group ##STR2## and n is 0 or an integer of 1 to 5, said Xs being the same or different when n is an integer of 2 to 5; and Y denotes a halogen atom, a lower alkyl group, nitro group, phenyl group, a lower alkoxy group or trifluoromethyl group and m is in integer of 1 to 3, said Ys being the same or different when m is 2 or 3.
摘要翻译：提供吡唑衍生物，其制剂，含有所述衍生物的选择性除草组合物和所述衍生物的用途。具有选择性除草活性的吡唑衍生物由式I表示：其中，A表示直链或支链的低级亚烷基或低级亚烷基; X表示卤素原子，硝基，低级烷基，低级卤代烷基，低级烷氧基，低级卤代烷氧基，低级烯基，苯基，氰基，苯氧基，低级烷氧基羰基，脂肪族或芳香族酰基，甲磺酰氧基或基团，n为0或1〜5的整数，所述X为2〜5的整数时相同或不同; Y表示卤原子，低级烷基，硝基，苯基，低级烷氧基或三氟甲基，m表示1〜3的整数，当m为2或3时，所述Y相同或不同。

2. 发明授权

US4643757A Herbicidal 4-benzoyl-1-methyl-5-hydroxypyrazoles 失效
标题翻译：除草4-苯甲酰基-1-甲基-5-羟基吡唑
公开(公告)号：US4643757A
公开(公告)日：1987-02-17
申请号：US735656
申请日：1985-05-20
申请人： Masatoshi Baba , Norio Tanaka , Takasi Ikai , Tsutomu Nawamaki , Masaji Matsunaga
发明人： Masatoshi Baba , Norio Tanaka , Takasi Ikai , Tsutomu Nawamaki , Masaji Matsunaga
IPC分类号： A01N43/56 , A01N47/18 , A01N57/16 , C07D231/22 , C07D231/24 , C07D405/12 , C07D409/12 , C07F9/6509 , C07D231/20 , C07F9/65
CPC分类号： C07D405/12 , A01N43/56 , A01N47/18 , A01N57/16 , C07D231/22 , C07D231/24 , C07D409/12 , C07F9/650929
摘要： Pyrazole derivatives, selective herbicidal compositions containing said derivatives and the use of said derivatives are provided. The pyrazole derivatives having selective herbicidal activity are represented by the formula I: ##STR1## wherein, X denotes a halogen, nitro or methanesulfonyl,Y denotes hydrogen, a lower alkyl or a halogen,Z denotes a halogen or methanesulfonyl, andR denotes hydrogen; an organic acid residue; a lower alkynyl; a lower alkyl or a lower alkenyl which may be substituted by a halogen, hydroxy, cyano or an alkoxycarbonyl; or a benzyl which may be substituted by a halogen, nitro or a lower alkyl.
摘要翻译：提供吡唑衍生物，含有所述衍生物的选择性除草组合物和所述衍生物的用途。具有选择性除草活性的吡唑衍生物由式I表示：其中X表示卤素，硝基或甲磺酰基，Y表示氢，低级烷基或卤素，Z表示卤素或甲磺酰基， R表示氢; 有机酸残基; 低级炔基; 可被卤素，羟基，氰基或烷氧基羰基取代的低级烷基或低级烯基; 或可被卤素，硝基或低级烷基取代的苄基。

3. 发明申请

US20090036385A1 Hair care preparation 审中-公开
标题翻译：护发准备
公开(公告)号：US20090036385A1
公开(公告)日：2009-02-05
申请号：US11921954
申请日：2006-01-18
申请人： Masaji Matsunaga
发明人： Masaji Matsunaga
IPC分类号： A61K31/711 , A61K38/02 , A61P17/14 , A61K31/7105
CPC分类号： A61K8/64 , A61K8/606 , A61K8/987 , A61K8/99 , A61Q7/00
摘要： It is intended to provide a hair care preparation. The invention is directed to a hair care preparation (a hair regrowth agent, a hair restorer or an agent for preventing hair loss) comprising as an effective component, an enzymatic or hydrolytic degradation product of a nucleoprotein and/or DNA or RNA, a deoxyoligonucleotide, a deoxymononucleotide, an oligopeptide, an oligonucleotide or a mononucleotide separated from the degradation product, or a mixture of at least two members selected from the degradation products or compounds. The effective component such as a deoxyloligonucleotide has a relatively small molecular weight, therefore, it is easy to be percutaneously absorbed. Further it has a cell activation effect and a blood circulation-promoting effect when it is percutaneously absorbed. Therefore, when it is applied to the scalp, an excellent hair regrowth-promoting effect, hair restoration effect and effect of preventing hair loss are exhibited. The hair care preparation of the present invention is useful as a hair care pharmaceutical product, quasi-drug or cosmetic product for mammal, particularly for humans, or a preparation to be added thereto.
摘要翻译：旨在提供护发制剂。本发明涉及包含作为有效成分的核蛋白和/或DNA或RNA的酶促或水解降解产物，脱氧寡核苷酸的护发制剂（头发再生剂，毛发还原剂或预防脱发剂），从降解产物分离的脱氧单核苷酸，寡肽，寡核苷酸或单核苷酸，或选自降解产物或化合物的至少两种成分的混合物。脱氧寡核苷酸等有效成分的分子量比较小，容易被皮肤吸收。此外，当其经皮吸收时，其具有细胞活化作用和促进血液循环的作用。因此，当应用于头皮时，显示优异的头发再生促进效果，头发恢复效果和防止脱发的效果。本发明的护发制剂可用作哺乳动物，特别是人类的护发药物，准药物或化妆品或其加入的制剂。

4. 发明申请

US20080145440A1 Microparticle preparation and medical composition 审中-公开
标题翻译：微粒制备和医药成分
公开(公告)号：US20080145440A1
公开(公告)日：2008-06-19
申请号：US11812468
申请日：2007-06-19
申请人： Han Hee Cho , Long Hai Han , Kazuaki Matsumura , Sadami Tsutsumi , Suong Hyu Hyon , Masaji Matsunaga , Fumihito Yoshida
发明人： Han Hee Cho , Long Hai Han , Kazuaki Matsumura , Sadami Tsutsumi , Suong Hyu Hyon , Masaji Matsunaga , Fumihito Yoshida
IPC分类号： A61K33/24 , A61K31/282 , A61K47/30 , A61K9/14 , A61P35/00
CPC分类号： A61K45/06 , A61K9/0019 , A61K9/1629 , A61K9/1688 , A61K31/282 , A61K31/7088 , A61K33/24 , A61K2300/00
摘要： According to the present invention, an early-phase release amount of cisplatin (CCDP) is reduced and a release of cisplatin is maintained over a long period of time, such that an anticancer effect against cancer cells is enhanced while side effects are reduced. In this manner, a life prolongation effect for patients is enhanced. A microparticle preparation contains cisplatin that is intercalated into double-helical DNA. The microparticle preparation stably retains cisplatin and exhibits an excellent slow-release property. Accordingly, even when cisplatin containing severe toxicity is used, the side effects can be suppressed and an excellent anticancer effect can be provided over a long period of time.
摘要翻译：根据本发明，降低了顺铂（CCDP）的早期释放量，长时间维持顺铂的释放，从而增加抗癌细胞的抗癌作用，同时副作用降低。以这种方式，对患者的延长寿命的作用增强。微粒制剂含有插入双螺旋DNA的顺铂。微粒制剂稳定地保持顺铂并显示出优异的缓释性能。因此，即使使用含有严重毒性的顺铂，也可以抑制副作用，能够长时间地提供优异的抗癌作用。

5. 发明申请

US20060110816A1 Method of concentrating and removing harmful substance using double-stranded dna and adsorbent and apparatus therefor 审中-公开
标题翻译：使用双链dna和吸附剂浓缩和去除有害物质的方法及其设备
公开(公告)号：US20060110816A1
公开(公告)日：2006-05-25
申请号：US10542430
申请日：2003-11-17
申请人： Xiang Liu , Masaji Matsunaga , Norio Nishi
发明人： Xiang Liu , Masaji Matsunaga , Norio Nishi
IPC分类号： B09C1/10
CPC分类号： B01D61/243 , A23C7/04 , B01D15/00 , B01D61/28 , B01D63/02 , B01D2313/40 , B01J20/24 , B01J20/2805 , C02F1/286 , C02F1/288 , C02F1/44 , C02F2101/36 , C02F2101/366 , C02F2303/16
摘要： There is provided a method of removing harmful substance characterized by comprising contacting a harmful substance-containing liquid to be treated with a double-stranded DNA, adsorbing the harmful substance onto the double-stranded DNA through intercalation, and separating it. The method is particularly useful for removing dioxins, and can be carried out by contacting a liquid to be treated with an adsorbent comprising a double-stranded DNA or a solution containing a double-stranded DNA enclosed in a container or a bag made of a membrane that is permeable for the harmful substance but is not permeable for the double-stranded DNA.
摘要翻译：提供了除去有害物质的方法，其特征在于包括使待处理的有害物质的液体与双链DNA接触，通过插入将有害物质吸附到双链DNA上，并将其分离。该方法特别可用于除去二恶英，并且可以通过使待处理的液体与包含双链DNA的吸附剂或包含在容器中的双链DNA的溶液或由膜制成的袋接触来进行对于有害物质是可渗透的，但对双链DNA不可渗透。

6. 发明授权

US5014604A Piston for internal combustion engine 失效
标题翻译：内燃机活塞
公开(公告)号：US5014604A
公开(公告)日：1991-05-14
申请号：US421106
申请日：1989-10-13
申请人： Sumio Hirao , Masaji Matsunaga , Yoshihiro Yamada
发明人： Sumio Hirao , Masaji Matsunaga , Yoshihiro Yamada
IPC分类号： F02B3/06 , F02F3/00 , F02F3/08 , F02F3/12 , F16J1/01
CPC分类号： F02F3/12 , F02F3/0015 , F02B3/06 , F05C2201/021 , F05C2251/042 , F05C2253/16
摘要： An internally-chilled piston for an internal combustion engine is provided. This piston comprises a piston body made of an aluminum alloy and a piston head including a cylindrical member and a ring-shaped member engaging the outer peripheral surface of the cylindrical member by a shrink fit bonding. The cylindrical member constitutes the central portion of the piston head, while the ring-shaped member constitutes the periphery thereof. On the surface of the ring-shaped member which contacts with the melt forming the piston body during casting, an aluminized layer is formed which chemically connects the ring-shaped member and the piston body to increase the mechanical strength of bonding therebetween.
摘要翻译：提供一种用于内燃机的内部冷却活塞。该活塞包括由铝合金制成的活塞体和包括圆柱形构件的活塞头和通过收缩配合接合与圆柱形构件的外周表面接合的环形构件。圆柱形构件构成活塞头的中心部分，而环形构件构成其周边。在铸造时与形成活塞体的熔体接触的环状构件的表面形成有铝化层，其化学连接环状构件和活塞体，以增加其间的结合的机械强度。

7. 发明申请

US20080314007A1 Filter for Air Conditioner Capable of Removing Toxic Substances 审中-公开
标题翻译：过滤器可以消除有毒物质的空调
公开(公告)号：US20080314007A1
公开(公告)日：2008-12-25
申请号：US12087991
申请日：2006-01-18
申请人： Masaji Matsunaga
发明人： Masaji Matsunaga
IPC分类号： B01D50/00
CPC分类号： B01D39/1623 , B01D2239/0407
摘要： There is provided a filter simultaneously having the effects of not only being capable of effectively remove toxic substances such as benzo[a]pyrene, contained in outdoor air and indoor air but also being substantially free from any deterioration of dust collection effectiveness.The air conditioner filter which is installed to an air passage of an air conditioner that intakes outdoor air into an equipment interior and also has a mechanism for circulating air in the equipment interior, comprising: a filter base material constituted from a monolayer sheet of nonwoven fabric, or from a laminate that includes nonwoven fabric sheets; and DNA microparticles supported in the filter base material and capable of intercalation trapping of toxic substances such as benzo [a]pyrene; wherein the DNA microparticles is constituted of microparticles of 50 to 2000 μn average diameter whose double helix DNA is made to adhere to the surfaces of a carrier, by means of a binder if necessary, and the DNA microparticles are contained in an amount of 0.05 to 20% by mass based on the mass of the filter base material.
摘要翻译：同时提供了一种过滤器，其具有不仅能够有效地除去室外空气和室内空气中所含的苯并[a]芘等有害物质，而且基本上没有灰尘收集效果的劣化的效果。安装在空气调节器的空气通道中的空调过滤器，其将室外空气引入设备内部，并且还具有使设备内部的空气循环的机构，包括：由单层无纺布构成的过滤器基材，或由包括无纺布片的层压制品构成; 和支持在过滤基材中的DNA微粒，并能够插入捕获苯并[a]芘等有毒物质; 其特征在于，所述DNA微粒由必要时的粘合剂使双螺旋DNA附着于载体表面的平均直径为50〜2000μm的微粒构成，所述DNA微粒的含量为0.05〜相对于过滤器基材的质量为20质量％。

8. 发明申请

US20080161229A1 Compounding ingredients for basic cosmetics and basic cosmetics 审中-公开
标题翻译：基础化妆品和基本化妆品的复合成分
公开(公告)号：US20080161229A1
公开(公告)日：2008-07-03
申请号：US11902763
申请日：2007-09-25
申请人： Masaji Matsunaga , Fumito Yoshida , Takao Mori
发明人： Masaji Matsunaga , Fumito Yoshida , Takao Mori
IPC分类号： A61K8/00 , A61K8/49 , A61K8/64 , A61Q19/00 , C07H21/00 , C07K2/00
CPC分类号： A61Q19/08 , A61K8/606 , A61K8/64 , A61K8/987 , A61K8/99 , A61Q19/00 , A61Q19/02
摘要： The present invention relates to a compounding ingredients for basic cosmetics and basic cosmetics containing the compounding ingredients which contain enzymes or hydrolysis products of nucleoprotein and/or DNA or RNA, or deoxy oligonucleotide, deoxy mononucleotide, oligopeptide, oligonucleotide mononucleotide separated from the hydrolysis products, or at least two kinds of mixtures selected from the hydrolysis products or compounds as active ingredients. Because the active ingredients such as deoxy oligonucleotide and others have comparatively small molecular weights, they are easy to be absorbed percutaneously, and when they are percutaneously absorbed, they exhibit cellular stimulating effects and blood circulation promoting effects, and therefore, in the event that they are applied to the facial skin, they marvelously prevent skin roughness, blotches, freckles, wrinkles, etc. and exhibit superb skin-lightening effects.
摘要翻译：本发明涉及含有含有核糖蛋白和/或DNA或RNA的酶或水解产物或脱氧寡核苷酸，脱氧单核苷酸，寡肽，与水解产物分离的寡核苷酸单核苷酸的配混成分的碱性化妆品和碱性化妆品的配混成分，或选自水解产物或化合物中的至少两种混合物作为活性成分。由于活性成分如脱氧寡核苷酸等具有相对小的分子量，因此容易被经皮吸收，并且经皮吸收时，具有细胞刺激作用和血液循环促进作用，因此，如果它们适用于面部皮肤，极好地防止皮肤粗糙，斑点，雀斑，皱纹等，并具有极佳的皮肤亮白效果。

9. 发明授权

US5681403A Magnesium alloy 失效
标题翻译：镁合金
公开(公告)号：US5681403A
公开(公告)日：1997-10-28
申请号：US364050
申请日：1994-12-27
申请人： Kunihiko Makino , Toshiro Kawata , Kyosuke Kanemitsu , Koji Watanabe , Masaji Matsunaga , Mamoru Sayashi
发明人： Kunihiko Makino , Toshiro Kawata , Kyosuke Kanemitsu , Koji Watanabe , Masaji Matsunaga , Mamoru Sayashi
IPC分类号： C22C23/02 , C22C23/00
CPC分类号： C22C23/02
摘要： A magnesium Mg--Al--RE magnesium alloy wherein an amount of a rare earth component may be reduced while optimial tensile strength and durability are obtained. The Alloy further includes a small calcium component. A high degree of creep resistance is obtained. Further, additional copper and/or zinc components may be introduced together, or singly for providing favorable tensile characteristics to the alloy material.
摘要翻译：镁镁合金镁镁合金，其中可以减少稀土成分的量，同时获得最佳拉伸强度和耐久性。该合金还包括小的钙成分。获得高抗蠕变性。此外，另外的铜和/或锌组分可以一起引入，或者单独地用于为合金材料提供有利的拉伸特性。

10. 发明申请

US20090272392A1 Cigarette filter capable of removing harmful substance 审中-公开
标题翻译：能去除有害物质的香烟过滤器
公开(公告)号：US20090272392A1
公开(公告)日：2009-11-05
申请号：US11919217
申请日：2005-04-28
申请人： Xiang Dong Liu , Masaji Matsunaga , Norio Nishi
发明人： Xiang Dong Liu , Masaji Matsunaga , Norio Nishi
IPC分类号： A24D3/04
CPC分类号： A24D3/10 , A24D3/14
摘要： [PROBLEMS] To provide a cigarette filter that does not impair the distinctive flavor of a cigarette and the air permeability of filter while smoking, and at the same time, can more effectively remove harmful substances such as a pyrene that is generated from the cigarette.[MEANS FOR SOLVING PROBLEMS] The cigarette filter comprising a filter fiber bundle body which cigarette smoke passes through; a fine powder with a high surface area ratio that are mixed and scattered in the filter fiber bundle body; and a double-stranded DNA molecule attached to the outer surface of the fine powder with a high surface area ratio, characterized in that harmful substances such as benzo[a]pyrene contained in the cigarette smoke can be removed by intercalation into the double-stranded DNA molecule.
摘要翻译：本发明提供一种香烟过滤嘴，其不会损害香烟的独特风味，同时吸烟时的过滤器的透气性，同时可以更有效地除去由香烟产生的芘等有害物质。解决问题的手段香烟过滤嘴包括香烟烟雾通过的过滤纤维束体; 在过滤纤维束体中混合分散有高表面积比的细粉末; 和具有高表面积比的细粉末外表面附着的双链DNA分子，其特征在于，通过插入双链中除去香烟烟雾中含有的苯并[a]芘等有害物质 DNA分子。

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