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    • 1. 发明授权
    • Pharmaceutical composition and method using antifungal agent in combination
    • 联合使用抗真菌剂的药物组合物和方法
    • US08993603B2
    • 2015-03-31
    • US11910999
    • 2006-04-05
    • Nobuhiko NomuraHiroshi NishikawaNoritomo Fujino
    • Nobuhiko NomuraHiroshi NishikawaNoritomo Fujino
    • A01N43/64A61K31/41A61K45/06A61K31/4196A61K31/445A61K31/7048
    • A61K45/06A61K31/4196A61K31/445A61K31/7048A61K2300/00
    • A pharmaceutical composition containing one or more antifungal agents selected from an arylamidine derivative represented by the general formula: (wherein R1 represents an amidino group that may be substituted with a hydroxyl group that may be protected with an acyl group, an amidino group that may be substituted with an alkoxy group that may be substituted, or an amidino group that may be substituted with an aralkyloxy group that may be substituted; R2 and R3 identically or differently represent a hydrogen atom or a halogen atom) or a salt thereof, an azole antifungal agent, a polyene antifungal agent, a candin antifungal agent and a fluoropyrimidine antifungal agent has a strong antifungal activity and is useful for the treatment of fungal infection. A method for using them in combination is useful as an excellent therapeutic method for fungal infection. A pharmaceutical composition containing the arylamidine derivative represented by the above general formula or a salt thereof and an immunosuppressant has a strong antifungal activity and is useful for the treatment of fungal infection and a skin disease such as atopic dermatitis. A method for using them in combination is useful as an excellent therapeutic method for fungal infection and a skin disease such as atopic dermatitis.
    • 一种含有一种或多种抗真菌剂的药物组合物,其选自由以下通式表示的芳基脒衍生物:(其中R1表示可被可被酰基保护的羟基取代的脒基,可以是酰基的脒基) 被可被取代的烷氧基取代,或被可被取代的芳烷氧基取代的脒基; R2和R3相同或不同地表示氢原子或卤素原子)或其盐,唑类抗真菌剂 药剂,多烯抗真菌剂,栀子抗真菌剂和氟嘧啶抗真菌剂具有很强的抗真菌活性,可用于治疗真菌感染。 组合使用它们的方法可用作真菌感染的优良治疗方法。 含有上述通式所示的芳基脒衍生物或其盐和免疫抑制剂的药物组合物具有很强的抗真菌活性,可用于治疗真菌感染和皮肤病如特应性皮炎。 组合使用它们的方法可用作真菌感染和皮肤疾病如特应性皮炎的优异治疗方法。
    • 2. 发明申请
    • PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION
    • 药物组合物和使用抗真菌剂组合的方法
    • US20090087480A1
    • 2009-04-02
    • US11910999
    • 2006-04-05
    • Nobuhiko NomuraHiroshi NishikawaNoritomo Fujino
    • Nobuhiko NomuraHiroshi NishikawaNoritomo Fujino
    • A61K9/127A61K31/44A61K31/496A61K31/436A61P31/10A61K31/422A61K31/497A61K31/4196
    • A61K45/06A61K31/4196A61K31/445A61K31/7048A61K2300/00
    • A pharmaceutical composition containing one or more antifungal agents selected from an arylamidine derivative represented by the general formula: (wherein R1 represents an amidino group that may be substituted with a hydroxyl group that may be protected with an acyl group, an amidino group that may be substituted with an alkoxy group that may be substituted, or an amidino group that may be substituted with an aralkyloxy group that may be substituted; R2 and R3 identically or differently represent a hydrogen atom or a halogen atom) or a salt thereof, an azole antifungal agent, a polyene antifungal agent, a candin antifungal agent and a fluoropyrimidine antifungal agent has a strong antifungal activity and is useful for the treatment of fungal infection. A method for using them in combination is useful as an excellent therapeutic method for fungal infection. A pharmaceutical composition containing the arylamidine derivative represented by the above general formula or a salt thereof and an immunosuppressant has a strong antifungal activity and is useful for the treatment of fungal infection and a skin disease such as atopic dermatitis. A method for using them in combination is useful as an excellent therapeutic method for fungal infection and a skin disease such as atopic dermatitis.
    • 一种含有一种或多种抗真菌剂的药物组合物,其选自由以下通式表示的芳基脒衍生物:(其中R1表示可被可被酰基保护的羟基取代的脒基,可以是酰基的脒基) 被可被取代的烷氧基取代,或被可被取代的芳烷氧基取代的脒基; R2和R3相同或不同地表示氢原子或卤素原子)或其盐,唑类抗真菌剂 药剂,多烯抗真菌剂,栀子抗真菌剂和氟嘧啶抗真菌剂具有很强的抗真菌活性,可用于治疗真菌感染。 组合使用它们的方法可用作真菌感染的优良治疗方法。 含有上述通式所示的芳基脒衍生物或其盐和免疫抑制剂的药物组合物具有很强的抗真菌活性,可用于治疗真菌感染和皮肤病如特应性皮炎。 组合使用它们的方法可用作真菌感染和皮肤疾病如特应性皮炎的优异治疗方法。
    • 3. 发明申请
    • SCREW-DRIVE CONVEYING APPARATUS
    • 螺丝传动装置
    • US20150291364A1
    • 2015-10-15
    • US14752349
    • 2015-06-26
    • Hiroshi NishikawaToshiyuki Iba
    • Hiroshi NishikawaToshiyuki Iba
    • B65G35/06
    • B65G35/066B61B13/12
    • A screw-drive conveying apparatus has on a conveying traveling body side, a first driven roller pair having a shorter distance between two driven front and rear rollers and a second driven roller pair having a longer distance between two driven front and rear rollers. A first screw shaft row with which the respective driven rollers of the first driven roller pair are engaged and a second screw shaft row with which the respective driven rollers of the second driven roller pair are engaged are provided on a traveling path side. The length of screw discontinued spaces between both screw shaft rows is equal to the distance between the driven rollers of the driven roller pair engaged with the screw shaft row on the upstream side.
    • 螺杆驱动输送装置具有输送行进体侧,在两个从动前后辊之间具有较短距离的第一从动辊对和在两个从动前辊和后辊之间具有较长距离的第二从动辊对。 第一从动辊对的从动辊与第一从动辊对啮合的第一螺纹轴列和第二从动辊对的各个从动辊与其啮合的第二螺杆轴列设置在行进路径侧。 两个螺杆轴列之间的螺钉中断空间的长度等于从动辊对的从动辊与上游侧的螺杆轴排啮合的距离。
    • 4. 发明授权
    • Image reading apparatus with cleaning member on one reading unit higher in cleaning ability than cleaning member on the other reading unit
    • 图像读取装置,其清洁部件在一个读取单元上的清洁能力高于另一个读取单元上的清洁部件
    • US08792145B2
    • 2014-07-29
    • US13016500
    • 2011-01-28
    • Hiroshi Nishikawa
    • Hiroshi Nishikawa
    • H04N1/04
    • H04N1/203H04N1/00909H04N1/121H04N1/193H04N1/2032
    • An image reading apparatus includes a conveying unit for conveying documents one by one, a first reading unit for optically reading the conveyed document through a first transparent member provided at a first reading position on a conveying path in the conveying unit, a first cleaning unit for cleaning the first transparent member provided at the first reading position, a second reading unit for optically reading the conveyed document through a second transparent member provided at a second reading position on the conveying path in the conveying unit and on a downstream side of the first reading position, and a second cleaning unit for cleaning the second transparent member provided at the second reading position. The second cleaning unit is higher in cleaning ability than the first cleaning unit.
    • 图像读取装置包括一个一个地传送文件的传送单元,用于通过设置在传送单元中的传送路径上的第一读取位置的第一透明构件光学地读取被传送文件的第一读取单元,用于 清洁设置在第一读取位置的第一透明构件,第二读取单元,用于通过设置在输送单元中的输送路径上的第二读取位置处的第二透明构件和第一读数的下游侧光学地读取被输送的原稿 位置,以及用于清洁设置在第二读取位置的第二透明构件的第二清洁单元。 第二清洁单元的清洁能力高于第一清洁单元。
    • 7. 发明授权
    • Image reading apparatus
    • 图像读取装置
    • US08503039B2
    • 2013-08-06
    • US12981843
    • 2010-12-30
    • Hiroshi Nishikawa
    • Hiroshi Nishikawa
    • H04N1/04H04N1/40
    • H04N1/12H04N1/00909H04N1/1235H04N1/125H04N1/193H04N2201/0081
    • In an image reading apparatus, a white reference member for obtaining a reference value used in shading correction in the reading mechanism and an elastic member for cleaning a surface of the transparent member are provided such that respective positions of the white reference member and the elastic member with respect to the transparent member are variable. A controller controls the positions of these members with respect to the transparent member to alternately achieve movement of the white reference member to a position where the white reference member faces the transparent member and movement of the elastic member to a position where the elastic member faces the transparent member. The controller calculates the above reference value using a plurality of detection values read by the reading mechanism through the above positional control.
    • 在图像读取装置中,设置用于获得在读取机构中的阴影校正中使用的基准值的白色基准部件和用于清洁透明部件的表面的弹性部件,使得白色基准部件和弹性部件 相对于透明构件是可变的。 控制器控制这些构件相对于透明构件的位置,以交替地实现白色基准构件到白色基准构件面对透明构件的位置的移动,并且弹性构件移动到弹性构件面向的位置 透明会员 控制器使用通过上述位置控制由读取机构读取的多个检测值来计算上述基准值。
    • 8. 发明授权
    • Circuit modules and method of managing the same
    • 电路模块及其管理方法
    • US08431827B2
    • 2013-04-30
    • US13155463
    • 2011-06-08
    • Hiroshi NishikawaTaro Hirai
    • Hiroshi NishikawaTaro Hirai
    • H05K1/00
    • H05K1/0266H05K2201/09927Y10T29/49108Y10T29/49115Y10T29/49121Y10T29/49155
    • Circuit modules including identification codes and a method of managing them are provided. A module substrate includes signal input output terminals and outer ground terminals provided at the peripheral portions of a surface which becomes a mounting surface when the circuit module is completed. An inner-ground-terminal formation area surrounded by the signal input output terminals and the outer ground terminals includes a plurality of inner ground terminals arranged in a matrix of rows and columns. One of the edge portions is a direction identification area. The inner ground terminal is not provided in the direction identification area, and a first identification code having information about the position of the module substrate is provided in the direction identification area.
    • 提供了包括识别码的电路模块及其管理方法。 模块基板包括设置在电路模块完成时成为安装表面的表面的周边部分处的信号输入端子和外部接地端子。 由信号输入输出端子和外部接地端子包围的内部 - 地面端子形成区域包括以行和列为矩阵排列的多个内部接地端子。 边缘部分之一是方向识别区域。 内部接地端子不设置在方向识别区域,并且具有关于模块基板的位置的信息的第一识别码被提供在方向识别区域。