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1. 发明申请

US20130137111A1 DETECTION METHOD OF NOVEL RET FUSION 审中-公开
标题翻译：新型RET融合检测方法
公开(公告)号：US20130137111A1
公开(公告)日：2013-05-30
申请号：US13812356
申请日：2011-07-22
申请人： Nobuaki Shindo , Kouichi Nishimura , Yorikata Sano , Makoto Asaumi , Aya Yamanaka , Takashi Futami , Tatsuya Kawase
发明人： Nobuaki Shindo , Kouichi Nishimura , Yorikata Sano , Makoto Asaumi , Aya Yamanaka , Takashi Futami , Tatsuya Kawase
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2525/155 , C12Q2600/118 , G01N33/57484
摘要： It was found that a new fusion gene of a portion of the KIF5B gene and a portion of the RET gene, which is present in a portion of cancer patients, is a gene responsible for cancer. Based on this finding, detection methods of a polynucleotide as the gene and a polypeptide encoded by the polynucleotide were established. The detection methods involve detecting a fusion gene of a portion of the KIF5B gene and a portion of the RET gene, or a fusion protein encoded by such a fusion gene. The primer sets and the detection kits comprise sense primers designed from a portion encoding KIF5B and antisense primers designed from a portion encoding RET.
摘要翻译：发现KIF5B基因的一部分的新融合基因和存在于癌症患者的一部分中的RET基因的一部分是导致癌症的基因。基于该发现，建立了作为基因的多核苷酸的检测方法和由多核苷酸编码的多肽。检测方法包括检测KIF5B基因的一部分和RET基因的一部分的融合基因或由这种融合基因编码的融合蛋白。引物组和检测试剂盒包括从编码KIF5B的部分和从编码RET的部分设计的反义引物设计的有义引物。

2. 发明授权

US09267176B2 Method for detecting novel FGFR4 mutant 有权
标题翻译：检测新型FGFR4突变体的方法
公开(公告)号：US09267176B2
公开(公告)日：2016-02-23
申请号：US14236993
申请日：2012-08-03
申请人： Takashi Futami , Tatsuya Kawase , Nobuaki Shindou , Rumi Takeshita
发明人： Takashi Futami , Tatsuya Kawase , Nobuaki Shindou , Rumi Takeshita
IPC分类号： G01N33/53 , C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： [Problem] An object of the present invention is to elucidate a novel genetic mutation which is a cause of cancer, and thereby, to provide a method for detecting the genetic mutation, or a protein which has the mutation, a method for detecting the presence of cancer in a subject, a method for diagnosing cancer in a subject, and a primer set, a probe and a detecting kit for the methods.[Means for Solution] A method for detecting a fibroblast growth factor receptor 4 (FGFR4) mutant in a subject, which comprises a step of detecting the presence of the mutation of glycine at position 183 in a FGFR4 tyrosine kinase domain to cysteine in a sample obtained from the subject.
摘要翻译：本发明的目的是阐明作为癌症的原因的新型遗传突变，从而提供检测遗传突变的方法或具有突变的蛋白质，检测存在的方法受试者中的癌症，用于诊断受试者中的癌症的方法，以及用于该方法的引物组，探针和检测试剂盒。 [解决方案]一种检测受试者中成纤维细胞生长因子受体4（FGFR4）突变体的方法，其包括检测在FGFR4酪氨酸激酶结构域中的位置183处的甘氨酸突变存在于样品中的半胱氨酸的步骤从主题获得。

3. 发明申请

US20140220035A1 METHOD FOR DETECTING NOVEL FGFR4 MUTANT 有权
标题翻译：检测新型FGFR4突变体的方法
公开(公告)号：US20140220035A1
公开(公告)日：2014-08-07
申请号：US14236993
申请日：2012-08-03
申请人： Takashi Futami , Tatsuya Kawase , Nobuaki Shindou , Rumi Takeshita
发明人： Takashi Futami , Tatsuya Kawase , Nobuaki Shindou , Rumi Takeshita
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： [Problem] An object of the present invention is to elucidate a novel genetic mutation which is a cause of cancer, and thereby, to provide a method for detecting the genetic mutation, or a protein which has the mutation, a method for detecting the presence of cancer in a subject, a method for diagnosing cancer in a subject, and a primer set, a probe and a detecting kit for the methods.[Means for Solution] A method for detecting a fibroblast growth factor receptor 4 (FGFR4) mutant in a subject, which comprises a step of detecting the presence of the mutation of glycine at position 183 in a FGFR4 tyrosine kinase domain to cysteine in a sample obtained from the subject.
摘要翻译：本发明的目的是阐明作为癌症的原因的新型遗传突变，从而提供检测遗传突变的方法或具有突变的蛋白质，检测存在的方法受试者中的癌症，用于诊断受试者中的癌症的方法，以及用于该方法的引物组，探针和检测试剂盒。 [解决方案]一种检测受试者中成纤维细胞生长因子受体4（FGFR4）突变体的方法，其包括检测在FGFR4酪氨酸激酶结构域中的位置183处的甘氨酸突变存在于样品中的半胱氨酸的步骤从主题获得。

4. 发明授权

US09903740B2 Rotation-angle detecting device, image processing apparatus, and rotation-angle detecting method 有权
公开(公告)号：US09903740B2
公开(公告)日：2018-02-27
申请号：US14554201
申请日：2014-11-26
申请人： Hirofumi Nishi , Tatsuya Kawase
发明人： Hirofumi Nishi , Tatsuya Kawase
IPC分类号： G01D5/245 , G06K9/52 , G06T1/00
CPC分类号： G01D5/2451 , G06K9/52 , G06T1/00
摘要： A rotation-angle detecting device includes: an angle detecting unit that detects a rotation angle of a rotating body on the basis of sinusoidal wave signals that multiple sensors arranged to have a phase difference output according to the rotation angle of the rotating body; and a resolution setting unit that allows change of a resolution of the rotation angle detected by the angle detecting unit.

5. 发明授权

US09255817B2 Rotation-angle detection device, image processing apparatus, and rotation-angle detection method 有权
标题翻译：旋转角度检测装置，图像处理装置以及旋转角度检测方法
公开(公告)号：US09255817B2
公开(公告)日：2016-02-09
申请号：US14279637
申请日：2014-05-16
申请人： Tatsuya Kawase
发明人： Tatsuya Kawase
IPC分类号： G01B7/00 , G01R33/022 , G01D5/14 , G01D5/244
CPC分类号： G01D5/145 , G01D5/2448
摘要： A rotation-angle detection device includes: an amplitude adjustment unit that performs correction to match amplitude values of multiple detection signals output from multiple rotation detection units to output corrected signals, the rotation detection units changing outputs in accordance with a rotation angle of a rotor and being provided such that the rotation detection units output the detection signals having different phases; a vector generation unit that performs addition and subtraction on two signals out of the corrected signals to generate two vector component signals that are perpendicular to each other; an amplitude correction unit that performs correction to match amplitudes of the two vector component signals to output corrected vector component signals; and a rotation-angle searching unit that searches for the rotation angle of the rotor on basis of a vector that is represented by the two corrected vector component signals to output a detection angle.
摘要翻译：旋转角度检测装置包括：振幅调整单元，其执行校正，以匹配从多个旋转检测单元输出的多个检测信号的振幅值，以输出校正信号，所述旋转检测单元根据转子的旋转角度改变输出，被设置为使得旋转检测单元输出具有不同相位的检测信号; 矢量生成单元，对经校正的信号进行两个信号的加减运算，生成彼此垂直的两个矢量分量信号; 幅度校正单元，执行校正以匹配两个矢量分量信号的幅度以输出校正的矢量分量信号; 以及旋转角搜索单元，其基于由两个校正矢量分量信号表示的矢量来搜索转子的旋转角度，以输出检测角度。

6. 发明授权

US09742425B2 Rotation detector and rotation detection method 有权
公开(公告)号：US09742425B2
公开(公告)日：2017-08-22
申请号：US14682194
申请日：2015-04-09
申请人： Tatsuya Kawase
发明人： Tatsuya Kawase
IPC分类号： G01B7/30 , H03M1/66 , G01D5/14 , G01D5/244 , H03M1/30
CPC分类号： H03M1/668 , G01D5/145 , G01D5/24471 , H03M1/303
摘要： A rotation detector detecting rotation of a rotor, based on a signal produced according to rotation of the rotor, having a waveform according to a rotational cycle thereof, includes a signal obtaining unit to obtain two signals having phases different from each other; a vector operating unit to determine a vector according to a rotational angle of the rotor, based on the two signals; and a rotation detecting unit to detect rotation of the rotor, based on the vector. The two signals are produced from two elements located at positions farthest in a rotational angle of the rotor among plural rotation detecting elements located at positions different from each other.

7. 发明授权

US06646915B2 Semiconductor device 有权
标题翻译：半导体器件
公开(公告)号：US06646915B2
公开(公告)日：2003-11-11
申请号：US10176656
申请日：2002-06-24
申请人： Tatsuya Kawase
发明人： Tatsuya Kawase
IPC分类号： G11C1600
CPC分类号： G11C29/50012 , G11C16/32 , G11C29/50
摘要： A semiconductor device comprises a nonvolatile memory (A) for storing information on a frequency of operation; a volatile memory (B) in which the information on the frequency of operation is rewritten; and a control device for transferring the information on the frequency of operation stored in the memory (A) to the memory (B), rewriting the transferred information in the memory (B), and returning the rewritten information to the memory (A).
摘要翻译：半导体器件包括用于存储关于操作频率的信息的非易失性存储器（A）其中重写关于操作频率的信息的易失性存储器（B）; 以及控制装置，用于将存储在存储器（A）中的操作频率的信息传送到存储器（B），将所传送的信息重写到存储器（B）中，并将重写的信息返回到存储器（A）。

8. 发明授权

US09435664B2 Rotation angle detector, rotation angle detection method, and image forming apparatus 有权
标题翻译：旋转角度检测器，旋转角度检测方法和图像形成装置
公开(公告)号：US09435664B2
公开(公告)日：2016-09-06
申请号：US14278069
申请日：2014-05-15
申请人： Tatsuya Kawase
发明人： Tatsuya Kawase
IPC分类号： G01B7/30 , G01D5/245
CPC分类号： G01D5/2451
摘要： Provided are a rotation angle detector and a rotation angle detecting method. Each of the rotation angle detector and rotation angle detecting method detects a rotation angle of a rotating body according to a plurality of detection signals that vary depending on the rotation angle of the rotating body and have phases different from each other, to output the detected rotation angle as a detection angle, generates pseudo harmonics based on a multiplied detection angle obtained by multiplying the detection signal by a specified number, and removes the pseudo harmonics from the detection signals, to output a corrected detection signals from which the pseudo harmonics are removed to the detecting of the rotation angle, the detection angle being generated based on the correction detection signals.
摘要翻译：提供旋转角度检测器和旋转角度检测方法。旋转角度检测器和旋转角度检测方法中的每一个根据根据旋转体的旋转角度而变化的多个检测信号来检测旋转体的旋转角度，并且具有彼此不同的相位，以输出检测到的旋转作为检测角度产生基于通过将检测信号乘以规定数目而获得的相乘检测角度的伪谐波，并且从检测信号中去除伪谐波，以将修正的检测信号从其中去除伪谐波被去除检测旋转角度，检测角度是根据校正检测信号产生的。

9. 发明申请

US20150153154A1 ROTATION-ANGLE DETECTING DEVICE, IMAGE PROCESSING APPARATUS, AND ROTATION-ANGLE DETECTING METHOD 有权
标题翻译：旋转角度检测装置，图像处理装置和旋转角度检测方法
公开(公告)号：US20150153154A1
公开(公告)日：2015-06-04
申请号：US14554201
申请日：2014-11-26
申请人： Hirofumi Nishi , Tatsuya Kawase
发明人： Hirofumi Nishi , Tatsuya Kawase
IPC分类号： G01B7/30 , G06K9/52 , G06T1/00 , G01B7/00
CPC分类号： G01D5/2451 , G06K9/52 , G06T1/00
摘要： A rotation-angle detecting device includes: an angle detecting unit that detects a rotation angle of a rotating body on the basis of sinusoidal wave signals that multiple sensors arranged to have a phase difference output according to the rotation angle of the rotating body; and a resolution setting unit that allows change of a resolution of the rotation angle detected by the angle detecting unit.
摘要翻译：旋转角度检测装置包括：角度检测单元，其基于正弦波信号检测旋转体的旋转角度，多个传感器被布置成根据旋转体的旋转角度输出相位差; 以及分辨率设定单元，其允许改变由角度检测单元检测到的旋转角度的分辨率。

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