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1. 发明申请

US20120197188A1 METHODS AND APPARATUS FOR DRUG MODELING AND DISPLAYING DRUG MODELS 有权
标题翻译：用于药物制剂和显示药物模型的方法和装置
公开(公告)号：US20120197188A1
公开(公告)日：2012-08-02
申请号：US13360642
申请日：2012-01-27
申请人： Noah Syroid , Dwayne R. Westenskow , James Agutter , Talmage D. Egan , Kenward B. Johnson
发明人： Noah Syroid , Dwayne R. Westenskow , James Agutter , Talmage D. Egan , Kenward B. Johnson
IPC分类号： A61M31/00
CPC分类号： G06F19/3437 , A61K31/02 , A61K31/05 , A61K31/08 , A61K31/4468 , A61K31/4535 , A61K31/454 , A61K45/06 , G06F19/00 , G06F19/3456 , G16H50/50 , A61K2300/00
摘要： Drug delivery models, displays, and systems may be configured to provide a clinician with readily intuitive information about the effects of one or more drugs on a subject. Interactive features may be included to provide a subject-specific model of the expected or predicted effects of one or more drugs on the subject. Additionally, interactive features that effect drug delivery to the subject may also be included. Drug delivery models, displays, and systems may be used in teaching, in advance of treatment, during treatment, or following treatment.
摘要翻译：药物递送模型，显示器和系统可以被配置为向临床医生提供关于一种或多种药物对受试者的影响的容易直观的信息。可以包括互动特征以提供一种或多种药物对受试者的预期或预测效果的受试者特异性模型。此外，还可以包括影响药物递送到受试者的交互式特征。药物递送模型，显示和系统可以在治疗之前，治疗期间或治疗后使用。

2. 发明申请

US20080234322A1 Methods and apparatus for drug modeling and displaying drug models 审中-公开
标题翻译：用于药物建模和显示药物模型的方法和装置
公开(公告)号：US20080234322A1
公开(公告)日：2008-09-25
申请号：US11725864
申请日：2007-03-20
申请人： Noah Syroid , Dwayne R. Westenskow , James Agutter , Talmage D. Egan , Kenward B. Johnson
发明人： Noah Syroid , Dwayne R. Westenskow , James Agutter , Talmage D. Egan , Kenward B. Johnson
IPC分类号： A61K31/4468 , A61K31/05 , A61K31/08 , A61K31/4535 , A61K31/454 , A61K31/02
CPC分类号： G16H50/50 , A61K31/02 , A61K31/05 , A61K31/08 , A61K31/4468 , A61K31/4535 , A61K31/454 , A61K45/06 , G06F19/3456 , A61K2300/00
摘要： Drug delivery models, displays, and systems may be configured to provide a clinician with readily intuitive information about the effects of one or more drugs on a subject. Interactive features may be included to provide a subject-specific model of the expected or predicted effects of one or more drugs on the subject. Additionally, interactive features that effect drug delivery to the subject may also be included. Drug delivery models, displays, and systems may be used in teaching, in advance of treatment, during treatment, or following treatment.
摘要翻译：药物递送模型，显示器和系统可以被配置为向临床医生提供关于一种或多种药物对受试者的影响的容易直观的信息。可以包括互动特征以提供一种或多种药物对受试者的预期或预测效果的受试者特异性模型。此外，还可以包括影响药物递送到受试者的交互式特征。药物递送模型，显示和系统可以在治疗之前，治疗期间或治疗后使用。

3. 发明授权

US08744779B2 Methods and apparatus for drug modeling and displaying drug models 有权
标题翻译：用于药物建模和显示药物模型的方法和装置
公开(公告)号：US08744779B2
公开(公告)日：2014-06-03
申请号：US13360642
申请日：2012-01-27
申请人： Noah Syroid , Dwayne R. Westenskow , James Agutter , Talmage D. Egan , Kenward B. Johnson
发明人： Noah Syroid , Dwayne R. Westenskow , James Agutter , Talmage D. Egan , Kenward B. Johnson
IPC分类号： G01N33/50 , G06F19/00
CPC分类号： G06F19/3437 , A61K31/02 , A61K31/05 , A61K31/08 , A61K31/4468 , A61K31/4535 , A61K31/454 , A61K45/06 , G06F19/00 , G06F19/3456 , G16H50/50 , A61K2300/00
摘要： Drug delivery models, displays, and systems may be configured to provide a clinician with readily intuitive information about the effects of one or more drugs on a subject. Interactive features may be included to provide a subject-specific model of the expected or predicted effects of one or more drugs on the subject. Additionally, interactive features that effect drug delivery to the subject may also be included. Drug delivery models, displays, and systems may be used in teaching, in advance of treatment, during treatment, or following treatment.
摘要翻译：药物递送模型，显示器和系统可以被配置为向临床医生提供关于一种或多种药物对受试者的影响的容易直观的信息。可以包括互动特征以提供一种或多种药物对受试者的预期或预测效果的受试者特异性模型。此外，还可以包括影响药物递送到受试者的交互式特征。药物递送模型，显示和系统可以在治疗之前，治疗期间或治疗后使用。

4. 发明授权

US07413546B2 Method and apparatus for monitoring dynamic cardiovascular function using n-dimensional representations of critical functions 失效
标题翻译：使用关键功能的n维表示监测动态心血管功能的方法和装置
公开(公告)号：US07413546B2
公开(公告)日：2008-08-19
申请号：US10846956
申请日：2004-05-14
申请人： James Agutter , Noah Syroid , Julio C. Bermudez , Yinqi Zhang , Michael E. Holmes , Frank Drews , David Lee Strayer , Robert William Albert , Dwayne R. Westenskow
发明人： James Agutter , Noah Syroid , Julio C. Bermudez , Yinqi Zhang , Michael E. Holmes , Frank Drews , David Lee Strayer , Robert William Albert , Dwayne R. Westenskow
IPC分类号： A61B5/02
CPC分类号： A61B5/00 , A61B5/02 , A61B5/0205 , A61B5/7445 , G06T11/206
摘要： A method, system, apparatus and device for the monitoring, diagnosis and evaluation of the state of a dynamic system is disclosed. This method and system provides the processing means for receiving sensed and/or simulated data, converting such data into a displayable object format and displaying such objects in a manner such that the interrelationships between the respective variables can be correlated and identified by a user. This invention provides for the rapid cognitive grasp of the overall state of a critical function with respect to a dynamic system. The system provides for displayed objects, which change in real-time to show the changes of the functions of the system. It is a highly flexible system which works with a wide variety of applications, including biological systems, environmental systems, engineering systems, economic systems, mechanical systems, chemical systems and the like. The device of this invention is adapted specifically to providing objects within a frame associated with other objects in a reference grid to provide a graphical representation of cardiovascular function.
摘要翻译：公开了用于动态系统的状态的监视，诊断和评估的方法，系统，装置和设备。该方法和系统提供了用于接收感测和/或模拟数据的处理装置，将这些数据转换成可显示对象格式，并以这样一种方式显示这些对象，使得各个变量之间的相互关系可以由用户相关和识别。本发明提供了关于动态系统的关键功能的总体状态的快速认知掌握。系统提供显示对象，实时更改以显示系统功能的更改。它是一个高度灵活的系统，适用于各种应用，包括生物系统，环境系统，工程系统，经济系统，机械系统，化学系统等。本发明的装置专门用于提供与参考网格中的其它物体相关联的框架内的物体，以提供心血管功能的图示。

5. 发明授权

US07774060B2 System for providing emergency medical care with real-time instructions and associated methods 有权
标题翻译：提供紧急医疗护理的实时指导和相关方法的系统
公开(公告)号：US07774060B2
公开(公告)日：2010-08-10
申请号：US11157218
申请日：2005-06-20
申请人： Dwayne R. Westenskow , Joseph A. Orr , Noah Syroid , Daniel Snell , James Agutter , Frank Drews , Srinath Lingutla , Santosh Balakrishnan , Kai Kuck , Lara Brewer
发明人： Dwayne R. Westenskow , Joseph A. Orr , Noah Syroid , Daniel Snell , James Agutter , Frank Drews , Srinath Lingutla , Santosh Balakrishnan , Kai Kuck , Lara Brewer
IPC分类号： A61N1/39
CPC分类号： G09B19/00 , A61M16/0051 , A61M16/024 , A61M16/1055 , A61M16/106 , A61M2205/502 , A61M2205/581 , A61M2205/583 , A61M2230/04 , A61M2230/205 , A61M2230/42 , A61M2230/432 , A61N1/39 , A61N1/3993 , G09B23/288
摘要： A basic life support system (BLSS) includes a processing element and an output element, such as a display screen or an audio output element, for providing an individual with real-time instructions on providing emergency medical care to a patient until paramedics or other healthcare professionals arrive to take over care for the patient. The instructions may be provided as graphics, including animations, as text, audibly, or as a combination of visible and audible elements. The BLSS may be configured for providing emergency medical care to individuals who have suffered from ventricular fibrillation. Accordingly, the BLSS may also include a defibrillation apparatus, an air or oxygen supply, a respiratory interface, one or more sensors, or a combination thereof.
摘要翻译：基本生命支持系统（BLSS）包括处理元件和诸如显示屏或音频输出元件的输出元件，用于向个人提供关于向患者提供紧急医疗护理的实时指令，直到护理人员或其他保健专业人员到医院接受治疗。指令可以作为图形，包括动画，文本，听觉地或作为可见和可听元素的组合来提供。 BLSS可能被配置为为患有心室颤动的个人提供紧急医疗。因此，BLSS还可以包括除颤装置，空气或氧气供应，呼吸界面，一个或多个传感器或其组合。

6. 发明授权

US07603631B2 Method and apparatus for monitoring dynamic systems using n-dimensional representations of critical functions 失效
标题翻译：用于使用关键功能的n维表示来监视动态系统的方法和装置
公开(公告)号：US07603631B2
公开(公告)日：2009-10-13
申请号：US10840835
申请日：2004-05-07
申请人： Julio C. Bermudez , Stefano Foresti , Dwayne R. Westenskow , James Agutter , Debra Gondeck-Becker
发明人： Julio C. Bermudez , Stefano Foresti , Dwayne R. Westenskow , James Agutter , Debra Gondeck-Becker
IPC分类号： G06F3/00 , A61B5/02
CPC分类号： A61B5/00 , A61B5/0205 , G06F19/00 , G16H50/20 , G16H50/50
摘要： A method, system and apparatus for the monitoring, diagnosis and evaluation of the state of a dynamic system is disclosed. This method and system provides the processing means for receiving sensed and/or simulated data, converting such data into a displayable object format and displaying such objects in a manner such that the interrelationships between the respective variables can be correlated and identified by a user. This invention provides for the rapid cognitive grasp of the overall state of a critical function with respect to a dynamic system. The system provides for displayed objects which change in real-time to show the changes of the functions of the system. It is a highly flexible system which works with a wide variety of applications, including biological systems, environmental systems, engineering systems, economic systems, mechanical systems, chemical systems and the like.
摘要翻译：公开了一种用于动态系统状态的监视，诊断和评估的方法，系统和装置。该方法和系统提供了用于接收感测和/或模拟数据的处理装置，将这些数据转换成可显示对象格式，并以这样的方式显示这些对象，使得各个变量之间的相互关系可以由用户相关和识别。本发明提供了关于动态系统的关键功能的总体状态的快速认知掌握。系统提供实时更改的显示对象，显示系统功能的变化。它是一个高度灵活的系统，适用于各种应用，包括生物系统，环境系统，工程系统，经济系统，机械系统，化学系统等。

7. 发明授权

US07891356B2 Method for reducing the effects of general anesthetics 有权
标题翻译：降低全身麻醉效果的方法
公开(公告)号：US07891356B2
公开(公告)日：2011-02-22
申请号：US11843994
申请日：2007-08-23
申请人： Joseph A. Orr , Dwayne R. Westenskow
发明人： Joseph A. Orr , Dwayne R. Westenskow
IPC分类号： A61M11/00
CPC分类号： A61M16/009 , A61M16/0045 , A61M16/0093 , A61M16/0833 , A61M16/085 , A61M16/0891 , A61M16/105 , A61M16/1055 , A61M16/106 , A61M16/22
摘要： An apparatus for reversing inhaled anesthesia, which is configured to be positioned along a breathing circuit or anesthesia delivery circuit, includes a filter for removing one or more anesthetic agents from gases passing therethrough, as well as a component for elevating CO2 levels in gases that are to be inhaled by an individual. The apparatus is configured to be positioned between a Y-connector of the breathing circuit and the portion of the breathing circuit that interfaces with the individual. The CO2 level-elevating component facilitates an increase in the ventilation of the individual without resulting in a significant decrease in the individual's PaCO2 level and, thus, a decrease in the rate at which blood flows through the individual's brain. A method of reversing the effects of inhaled anesthesia includes increasing the rate of ventilation of an anesthetized individual while causing the individual to inhale gases with elevated amounts of CO2 and while filtering anesthetic agents from such gases.
摘要翻译：用于反转吸入麻醉的装置，其被配置为沿着呼吸回路或麻醉输送回路定位，包括用于从通过其中的气体中去除一种或多种麻醉剂的过滤器，以及用于提高气体中的CO 2水平的组分，被个人吸入。该装置构造成位于呼吸回路的Y形连接器和与个体接触的部分呼吸回路之间。二氧化碳水平升高组件有助于个体的通气量增加，而不会导致个体PaCO2水平的显着降低，从而导致血液流过个体大脑的速度降低。一种逆转吸入麻醉效果的方法包括增加麻醉个体的通气率，同时使个体以较高量的CO 2吸入气体，同时从这些气体中过滤麻醉剂。

8. 发明申请

US20120055481A1 ANESTHESIA REVERSAL METHODS AND SYSTEMS 有权
标题翻译：麻醉反转方法和系统
公开(公告)号：US20120055481A1
公开(公告)日：2012-03-08
申请号：US13032499
申请日：2011-02-22
申请人： Joseph A. Orr , Derek Jo Sakata , Dwayne R. Westenskow
发明人： Joseph A. Orr , Derek Jo Sakata , Dwayne R. Westenskow
IPC分类号： A61M16/01
CPC分类号： A61M16/009 , A61M16/0045 , A61M16/0093 , A61M16/0833 , A61M16/085 , A61M16/0891 , A61M16/105 , A61M16/1055 , A61M16/106 , A61M16/22
摘要： An apparatus for reversing inhaled anesthesia, which may be configured to be positioned along a breathing circuit or anesthesia delivery circuit, includes an anesthesia removal component and a blood flow acceleration component. The blood flow acceleration component facilitates an increase in the ventilation of the individual without resulting in a significant decrease in the individual's PaCO2 level and, thus, a decrease in the rate at which blood flows through the individual's brain. A method of reversing the effects of inhaled anesthesia includes increasing the rate of ventilation of an anesthetized individual while causing the individual to inhale gases with at least atmospheric amounts of CO2.
摘要翻译：可以被配置为沿着呼吸回路或麻醉输送电路定位的用于逆转吸入麻醉的装置包括麻醉去除组件和血流加速组件。血液流动加速成分有助于个体的通气增加，而不会导致个体PaCO 2水平的显着降低，从而导致血液流过个体大脑的速率的降低。一种逆转吸入麻醉效果的方法包括增加麻醉个体的通气率，同时使个体吸入至少大气二氧化碳的气体。

9. 发明授权

US5230342A Blood pressure monitoring technique which utilizes a patient's supraorbital artery 失效
标题翻译：血液压力监测技术利用患者的副作用
公开(公告)号：US5230342A
公开(公告)日：1993-07-27
申请号：US752399
申请日：1991-08-30
申请人： Donald E. Bobo, Jr. , Dwayne R. Westenskow , Phillip D. Baker
发明人： Donald E. Bobo, Jr. , Dwayne R. Westenskow , Phillip D. Baker
IPC分类号： A61B5/022 , A61B5/021
CPC分类号： A61B5/021
摘要： There is disclosed herein a method of obtaining certain information about the blood pressure of a given patient by means of a particular blood pressure technique, specifically by means of oscillometry, in which the pressurizable pressure transducing bladder located adjacent and cooperating with a particular artery of the patient, is used in combination with means for pressurizing the bladder in a controlled way in order to provide the desired information. The particular artery used is the patient's supraorbital artery which is readily accessible in a specific area just above the eyebrow of substantially all patients. There is also disclosed herein a blood pressure transducing bladder assembly which is specifically designed to easily access the supraorbital artery of substantially all patients using the eyebrow and nose of each patient as a frame of reference.
摘要翻译：本文公开了一种通过特定的血压技术获得关于给定患者的血压的某些信息的方法，特别是通过示波器，其中位于邻近并与其的特定动脉配合的可加压压力换能囊患者，与用于以受控方式加压膀胱的装置组合使用，以便提供期望的信息。使用的特定动脉是患者的眶上动脉，其在刚好在基本上所有患者的眉毛上方的特定区域中容易接近。本文还公开了一种血压转换膀胱组件，其特别设计用于使用每个患者的眉毛和鼻子作为参考系，容易地接近基本上所有患者的眶上动脉。

10. 发明授权

US4211239A Neonatal oxygen consumption monitor 失效
标题翻译：新生儿氧气监测仪
公开(公告)号：US4211239A
公开(公告)日：1980-07-08
申请号：US902471
申请日：1978-05-03
申请人： Daniel B. Raemer , Dietrich K. Gehmlich , Dwayne R. Westenskow , Curtis C. Johnson, deceased
发明人： Daniel B. Raemer , Dietrich K. Gehmlich , Dwayne R. Westenskow , Curtis C. Johnson, deceased
IPC分类号： A61B5/083 , A61B5/113 , A61M16/10 , A61H1/00 , A61M16/00
CPC分类号： A61B5/083 , A61B5/113 , A61M16/10 , A61M2016/1025 , A61M2230/435
摘要： An oxygen consumption monitor system suitable for use in measuring oxygen uptake in neonates wherein the system includes a check valve system in combination with a high flow, positive-end-expiratory-pressure respirator for supplying a high volume, controlled flow of oxygen through a flow circuit which includes (1) a primary flow line for carrying most of the oxygen supply through a respirator circuit maintained at a positive pressure, and (2) a secondary outlet communicating from said primary flow line through the check valve combination to permit inspiration of oxygen from the respirator circuit and expiration to a separate chamber for measurement of oxygen consumption. Minimal deadspace is developed in the check valve combination to insure fresh oxygen supply with each inspiration by the neonate. The use of opposing oneway valves at inlet and outlet locations of the valve combination permits use of a single opening for coupling to an endotrachael tube. The reduced deadspace also enables accurate oxygen consumption measurement by cumulating the amounts of oxygen required to replenish the expired air to an oxygen concentration measured in the primary flow line.
摘要翻译：一种适用于测量新生儿氧吸收的氧气消耗监测系统，其中该系统包括与高流量正端呼气压呼吸器组合的止回阀系统，用于通过流量供应高体积，受控制的氧气流电路，其包括（1）用于通过保持在正压力的呼吸器回路承载大部分氧气供应的主流线，以及（2）从所述主流线通过止回阀组合连通以允许氧气吸入的次级出口从呼吸器电路和呼气到单独的室，用于测量氧气消耗。在止回阀组合中开发出最小的死空间，以确保新鲜氧气供应，每个新生儿的吸气。在阀组合的入口和出口处使用相对的单向阀允许使用单个开口来连接到内窥镜管。减少的死区还能够通过将补充呼出的空气所需的氧气量累积到在一次流动线中测得的氧浓度来测量精确的氧气消耗。

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