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    • 3. 发明申请
    • Lip Treatment Composition
    • 唇膏治疗组成
    • US20160354304A1
    • 2016-12-08
    • US15238906
    • 2016-08-17
    • Ronald Anderson
    • Ronald Anderson
    • A61K8/97A61Q19/00A61K8/92
    • A61K8/97A61K8/922A61K8/925A61K8/9789A61Q19/001
    • A lip treatment composition for creating a perceptible buzzing sensation when applied to mucosa membrane of a user. The composition has one or more base ingredients and at least one active ingredient comprising Zanthoxylum essential oil extracted in a liquid carbon dioxide process that induces a perceptible sensation reminiscent of electrical buzzing when applied to the mucosa membrane of the user. The Zanthoxylum essential oil could comprises between approximately 2.0000% and 4.0000% by weight of the composition and could comprise approximately 3.3000% by weight of the composition. The lip treatment composition can be formed under a process including heating the one or more base ingredients, adding the at least one active ingredient, and mixing the one or more base ingredients and the at least one active ingredient.
    • 一种唇膏治疗组合物,当用于使用者的粘膜时产生可感知的嗡嗡感。 所述组合物具有一种或多种基础成分,并且至少一种包含在液体二氧化碳方法中提取的花椒精油的活性成分,其在施用于使用者的粘膜时引起可感知的电嗡嗡声。 花椒精油可以占组合物重量的约2.0000%至4.0000%,并且可以占组合物重量的约3.3000%。 唇部处理组合物可以在包括加热一种或多种基础成分,加入至少一种活性成分和混合一种或多种基础成分和至少一种活性成分的方法下形成。
    • 6. 发明申请
    • Sewage dump system for RV, marine and other mobile vehicles
    • RV,海洋和其他移动车辆的排污系统
    • US20050150562A1
    • 2005-07-14
    • US11034033
    • 2005-01-12
    • Ronald Anderson
    • Ronald Anderson
    • B60R15/00E03C1/12
    • B60R15/00Y10T137/6855
    • The sewage dump system of this invention comprises an elongated housing adapted for support on a mobile vehicle, the housing having an elongated sewage hose storage compartment having a height slightly greater than the diameter of a storage hose and communicating at its open end with an adjoining space configured to contain a hose outlet fitting on the outlet end of the sewage hose, the storage hose being folded intermediate its ends for reception in the hose storage compartment for guidance therein between said folded condition within the compartment and an extended position with the hose fitting communicating with a sewage dump site. In one embodiment, a plurality of spaced rollers having concave peripheries are spaced apart along one longitudinal side of the storage compartment to facilitate guiding the storage hose during extension and retraction. In a second embodiment a yoke member having guide rollers on its spaced ends is connected to a line extending retractably from a rotary power source for movement between a position retracted within the hose compartment with the folded sewage hose and an extended position at the adjoining space for extending the sewage hose to a sewage dump site.
    • 本发明的排污系统包括适于在移动车辆上支撑的细长壳体,该壳体具有细长的污水软管储存室,其具有略高于存储软管的直径的高度,并且在其开口端与相邻的空间连通 配置为在污水软管的出口端容纳软管出口配件,储存软管折叠在其端部之间,用于接收在软管存储隔间中,用于在隔室内的所述折叠状态和延伸位置之间引导,其中软管接头连通 与污水处理站点。 在一个实施例中,具有凹形周边的多个间隔开的辊沿着储藏室的一个纵向侧面间隔开,以便于在延伸和缩回期间引导储存软管。 在第二实施例中,在其间隔开的端部上具有导向辊的轭构件连接到从旋转动力源可伸缩地延伸的线,用于在缩回到软管隔间内的位置与折叠的污水软管之间运动,并在相邻的空间处延伸的位置 将污水管道延伸到污水处理场。
    • 9. 发明授权
    • MDR resistance treatment and novel pharmaceutically active
riminophenazines
    • MDR抗性治疗和新型药学活性的riminophenazines
    • US5763443A
    • 1998-06-09
    • US738473
    • 1996-10-28
    • Constance Elizabeth MedlenRonald AndersonJohn Francis O'Sullivan
    • Constance Elizabeth MedlenRonald AndersonJohn Francis O'Sullivan
    • A61K31/498C07D241/46A61K31/495
    • A61K31/498
    • The invention concerns the new use of riminophenazines in the treatment of a patient who has built up, or could build up, resistance to a therapeutically active substance, such as a patient requiring treatment for cancer. The riminophenazine conveniently may be of the general formula (I). ##STR1## R.sup.1 is a hydrogen atom, a halogen atom or a (C.sub.1 -C.sub.3) alkyl, (C.sub.1 -C.sub.3) alkoxy, fluoromethoxy or trifluoromethyl radical, R.sup.2 is a hydrogen or halogen atom, R.sup.3 is selected from hydrogen, (C.sub.1 -C.sub.4) alkyl, N,N-dialkylamino alkyl, (C.sub.3 -C.sub.12) cycloalkyl, methylcyclohexyl, hydroxycyclohexyl, cycloalkylmethyl, piperidyl, alkyl substituted piperidyl or N-benzyl-substituted pipperidyl, R.sup.4 is a hydrogen or halogen atom or a (C.sub.1 -C.sub.3) alkyl, (C.sub.1 -C.sub.3) alkoxy, fluoromethoxy or trifluoromethyl radical, and n is 1, 2 or 3. The invention also provides novel riminophenazines of general formula (I), their preparation, and compositions containing them.
    • 本发明涉及用于治疗已经建立或可能增加对治疗活性物质(例如需要治疗癌症的患者)的患者的治疗的患者的新用途。 方便地可以具有通式(I)的riminophenazine。 (C 1 -C 3)烷基,(C 1 -C 3)烷氧基,氟甲氧基或三氟甲基,R 2是氢或卤素原子,R 3选自氢,(C 1 -C 4)烷基,N,N-二烷基氨基烷基, (C 3 -C 12)环烷基,甲基环己基,羟基环己基,环烷基甲基,哌啶基,烷基取代的哌啶基或N-苄基取代的哌啶子基,R4是氢或卤素原子或(C1-C3)烷基,(C1-C3)烷氧基, 或三氟甲基,n为1,2或3.本发明还提供通式(I)的新型riminophenazine,其制备方法和含有它们的组合物。
    • 10. 发明授权
    • Anti-parasitic activity
    • 抗寄生虫活性
    • US5763442A
    • 1998-06-09
    • US591032
    • 1996-01-25
    • Constance Elizabeth MedlenRonald Anderson
    • Constance Elizabeth MedlenRonald Anderson
    • C07D241/46A61K31/495A61K31/498A61P33/02A61K31/50
    • A61K31/498A61K31/495
    • The invention provides the use of a riminophenazine in the manufacture of a medicament to treat parasitic infections. The riminophenazine may be used for the prophylactic treatments of maleria or for the therapeutic treatment of maleria. A known anti-maleria drug, e.g. chloroquine or mefloquine may be administered as well. The riminophenazine may be a compound of the general formula: ##STR1## wherein: R.sup.1 is selected from hydrogen atoms, halogen atoms, alkyl, alkoxy and trifluoromethyl radicals, R.sub.2 is selected from hydrogen or halogen atoms, R.sup.3 is selected from hydrogen atoms, alkyl, substituted alkyl, cycloalkyl, cycloalkylalkyl, unsubstituted heterocyclic radicals, substituted heterocyclic radicals, unsubstituted heterocyclicalkyl and substituted heterocyclicalkyl radicals.
    • 本发明提供了在制备用于治疗寄生虫感染的药物中使用边缘吩吩嗪的用途。 所述的林必泛嗪可用于预防性治疗恶性肿瘤或用于治疗恶性肿瘤。 已知的抗疟药物,例如, 也可以施用氯喹或甲氟喹。 边缘吩吩嗪可以是以下通式的化合物:其中:R 1选自氢原子,卤素原子,烷基,烷氧基和三氟甲基,R 2选自氢或卤素原子,R 3选自氢 原子,烷基,取代的烷基,环烷基,环烷基烷基,未取代的杂环基,取代的杂环基,未取代的杂环烷基和取代的杂环烷基。