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1. 发明申请

US20060161243A1 S-shaped stent design 有权
标题翻译： S形支架设计
公开(公告)号：US20060161243A1
公开(公告)日：2006-07-20
申请号：US11297913
申请日：2005-12-08
申请人： Neal Fearnot , Blayne Roeder , Alan Leewood , Jichao Sun
发明人： Neal Fearnot , Blayne Roeder , Alan Leewood , Jichao Sun
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/91 , A61F2250/0037 , A61F2250/0039
摘要： A variable curvature stent limb is disclosed herein. A stent derived from a plurality of these variable curvature stent limbs may be highly compressible, such that it is compatible with a low-profile delivery device. This stent may be useful over a wider range of body vessel diameters and may possess a greater fatigue life, since this stent may provide a more controlled constant radial force.
摘要翻译：本文公开了一种可变曲率支架肢体。衍生自多个这些可变曲率支架肢体的支架可以是高度可压缩的，使得其与低调输送装置兼容。该支架可以在更宽范围的体血管直径上有用，并且可以具有更大的疲劳寿命，因为该支架可以提供更受控制的恒定径向力。

2. 发明申请

US20050273155A1 Endoluminal device with extracellular matrix material and methods 有权
标题翻译：腔内装置与细胞外基质材料及方法
公开(公告)号：US20050273155A1
公开(公告)日：2005-12-08
申请号：US11094021
申请日：2005-03-30
申请人： Clinton Bahler , Michael DeBruyne , Neal Fearnot , Alan Leewood , Jason Mead , Thomas Osborne , Jichao Sun
发明人： Clinton Bahler , Michael DeBruyne , Neal Fearnot , Alan Leewood , Jason Mead , Thomas Osborne , Jichao Sun
IPC分类号： A61F2/00 , A61F2/06
CPC分类号： A61F2/07 , A61F2/0077 , A61F2/848 , A61F2/89 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0065
摘要： An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings.
摘要翻译：腔内装置包括支架和由支架支撑的管状移植物。移植物具有近端和远端开口，并且包括合成材料和生物可重构材料。生物可重塑材料设置在邻近近端和远端开口中的至少一个的至少一个带中的外表面上。

3. 发明授权

US10265200B2 Medical prostheses having bundled and non-bundled regions 有权
公开(公告)号：US10265200B2
公开(公告)日：2019-04-23
申请号：US13814179
申请日：2010-08-10
申请人： Steven J. Charlebois , William Kurt Dierking , Matthew S. Huser , Keith Milner , Jichao Sun
发明人： Steven J. Charlebois , William Kurt Dierking , Matthew S. Huser , Keith Milner , Jichao Sun
IPC分类号： A61F2/82 , A61F2/07 , A61F2/89
摘要： The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

4. 发明申请

US20100256736A1 COVERED BALLOON EXPANDABLE STENT DESIGN AND METHODOF COVERING 审中-公开
标题翻译：覆盖气球膨胀的设计和覆盖方法
公开(公告)号：US20100256736A1
公开(公告)日：2010-10-07
申请号：US12817845
申请日：2010-06-17
申请人： JAMES D. PURDY , Richard A. Swift , Blayne A. Roeder , Alan R. Leewood , Jichao Sun
发明人： JAMES D. PURDY , Richard A. Swift , Blayne A. Roeder , Alan R. Leewood , Jichao Sun
IPC分类号： A61F2/82 , B05D3/12
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： A balloon expandable covered stent consists of a plurality of primary stent units, each having an undulating shape defined by a series of primary strut members converging to form peaks and valleys. The primary stent units are assembled into a single cylindrical structure of the stent by connecting corresponding peaks with secondary strut members. Generally, surfaces of the stent may then coated with a polymeric, hyper-elastic material, preferably Thoralon®, by pre-expanding the stent prior to coating.
摘要翻译：球囊可扩张覆盖的支架由多个主支架单元组成，每个支架单元具有由一系列主要支柱构件限定的起伏形状，所述主支柱构件会聚以形成峰和谷。通过将相应的峰与辅助支柱构件相连，主支架单元组装成支架的单个圆柱形结构。通常，支架的表面可以在涂覆之前通过预扩张支架来涂覆聚合物超弹性材料，优选为Thoralon。

5. 发明授权

US08231929B2 Medical device coating process 有权
标题翻译：医疗器械涂装工艺
公开(公告)号：US08231929B2
公开(公告)日：2012-07-31
申请号：US11877369
申请日：2007-10-23
申请人： Jichao Sun
发明人： Jichao Sun
IPC分类号： A61L33/00
CPC分类号： B05D1/002 , B05C7/00 , B05C7/06 , B05C7/08 , B05C13/00 , B05C13/02 , B05D1/28 , B05D3/0254 , B05D7/22 , B05D7/52 , B05D2254/04
摘要： Methods for coating medical devices for implantation within a body vessel are provided comprising providing a cylindrical container, placing a medical device inside the cylindrical container, and applying a polymer in liquid form inside the container.
摘要翻译：提供用于涂覆在体内容器内植入的医疗装置的方法，包括提供圆柱形容器，将医疗装置放置在圆柱形容器内，以及将液体形式的聚合物涂覆在容器内。

6. 发明授权

US07887576B2 Endoluminal device with extracellular matrix material and methods 有权
标题翻译：腔内装置与细胞外基质材料及方法
公开(公告)号：US07887576B2
公开(公告)日：2011-02-15
申请号：US12468383
申请日：2009-05-19
申请人： Clinton D. Bahler , Michael P. DeBruyne , Neal E. Fearnot , Alan R. Leewood , Jason A. Mead , Thomas A. Osborne , Jichao Sun , Lal Ninan
发明人： Clinton D. Bahler , Michael P. DeBruyne , Neal E. Fearnot , Alan R. Leewood , Jason A. Mead , Thomas A. Osborne , Jichao Sun , Lal Ninan
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/0077 , A61F2/848 , A61F2/89 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0065
摘要： An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings.
摘要翻译：腔内装置包括支架和由支架支撑的管状移植物。移植物具有近端和远端开口，并且包括合成材料和生物可重构材料。生物可重塑材料设置在邻近近端和远端开口中的至少一个的至少一个带中的外表面上。

7. 发明申请

US20100219562A1 METHODS OF MAKING AN ENDOVASCULAR PROSTHESIS USING A DEFORMABLE MATRIX 有权
标题翻译：使用可变矩阵进行血管内皮生长的方法
公开(公告)号：US20100219562A1
公开(公告)日：2010-09-02
申请号：US12598249
申请日：2008-05-19
申请人： Jichao Sun
发明人： Jichao Sun
IPC分类号： B29C41/42
CPC分类号： B05D1/286 , A61L31/04 , A61L31/10 , A61L2420/02 , A61L2420/08 , B05D3/12 , B05D7/52
摘要： A method of making an endovascular prosthesis comprises the steps of applying a first layer of polymer to a portion of a deformable matrix, contacting a stent with the polymer to deform the matrix, applying a second layer of polymer over at least a portion of the stent and first layer, solidifying the layers of polymer to form the endovascular prosthesis, and removing the matrix.
摘要翻译：制造血管内假体的方法包括以下步骤：将第一层聚合物施加到可变形基质的一部分上，使支架与聚合物接触以使基质变形，在支架的至少一部分上施加第二层聚合物和第一层，固化聚合物层以形成血管内假体，并除去基质。

8. 发明申请

US20070010874A1 Branch vessel stent graft 有权
标题翻译：支血管支架移植
公开(公告)号：US20070010874A1
公开(公告)日：2007-01-11
申请号：US11481763
申请日：2006-07-06
申请人： Jichao Sun
发明人： Jichao Sun
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2220/005 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： A stent graft (10) has a tubular body of a biocompatible material and a side arm (20) fastened to the tubular body. A tubular extension piece (24) is sealingly joined to the end of the side arm and extends from it. It can be joined with adhesive or stitching. The extension piece can be formed from an elastomeric biocompatible material such as Thoralon™. The extension piece can have a resilient reinforcement 44 embedded into it and extending longitudinally. The extension piece is tucked back into the side arm during deployment of the stent graft into a body lumen.
摘要翻译：支架移植物（10）具有生物相容性材料的管状体和紧固到管状体的侧臂（20）。管状延伸件（24）密封地连接到侧臂的端部并从其延伸。它可以粘合或缝合。延伸件可以由诸如Thoralon TM的弹性生物相容性材料形成。延伸件可以具有嵌入其中并纵向延伸的弹性加强件44。在将支架移植物部署到体腔内时，延伸片被折回到侧臂中。

9. 发明申请

US20130211497A1 MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS 审中-公开
标题翻译：具有组合和非完整区域的医疗前景
公开(公告)号：US20130211497A1
公开(公告)日：2013-08-15
申请号：US13814179
申请日：2010-08-10
申请人： Steven J. Charlebois , William Kurt Dierking , Matthew S. Huser , Keith Milner , Jichao Sun
发明人： Steven J. Charlebois , William Kurt Dierking , Matthew S. Huser , Keith Milner , Jichao Sun
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61F2/07 , A61F2/89 , A61F2002/075 , A61F2250/0017 , A61F2250/0028
摘要： The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.
摘要翻译：本实施例提供具有相对低的传送轮廓的腔内假体，例如支架移植物。在一个实施例中，假体包括膜和至少一个具有收缩和扩张状态的支架，其中支架联接到膜并且保持开放状态处于膨胀状态。假体还可以包括沿着假体的长度和圆周布置在预定位置处的选择性地定向的轴向和/或周向纤维。圆周和/或轴向纤维的增加的人口密度可以设置在其中至少一个支架部分附接到膜的区域中，或者在施加在内腔假体上的较高生理负荷的区域中。沿着假体的长度和周长的预定位置选择性地定向轴向纤维和周向纤维，但不是沿着整个假体连续地定向，从而显着减少由于移植材料的减少导致的输送轮廓。

10. 发明授权

US07815687B2 Method of promoting cell proliferation and ingrowth by injury to the native tissue 有权
标题翻译：通过损伤天然组织促进细胞增殖和向内生长的方法
公开(公告)号：US07815687B2
公开(公告)日：2010-10-19
申请号：US12337163
申请日：2008-12-17
申请人： Clinton D. Bahler , Alan R. Leewood , Jichao Sun
发明人： Clinton D. Bahler , Alan R. Leewood , Jichao Sun
IPC分类号： A61F2/06 , A61F2/00
CPC分类号： A61F2/91 , A61F2002/0086 , A61F2220/0008 , A61F2220/0016 , Y10S623/901
摘要： The present invention relates to methods of treating tissue of the human body, specially, methods of promoting cell proliferation and ingrowth around implantable medical devices. The methods include inserting an apparatus comprising asperities adapted to injure native tissue at a desired anchoring location, injuring the native tissue at the desired anchoring location with the apparatus to initiate an injury response in the native tissue to thereby promote cell proliferation and ingrowth; and implanting the medical device at the treatment location.
摘要翻译：本发明涉及治疗人体组织的方法，特别是促进可植入医疗器械周围的细胞增殖和向内生长的方法。所述方法包括插入装置，其包括适于在期望的锚固位置处伤害天然组织的凹凸，用设备在期望的锚定位置损伤天然组织以在天然组织中引发损伤反应，从而促进细胞增殖和向内生长; 以及将医疗装置植入治疗位置。

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