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1. 发明申请

US20050118594A1 Enzymes 审中-公开
标题翻译：酶
公开(公告)号：US20050118594A1
公开(公告)日：2005-06-02
申请号：US10498788
申请日：2002-12-12
申请人： Narinder Chawla , Soo Lee , Huijun Ring , Ernestine Lee , Ian Forsythe , Reena Khare , Uyen Tran , Amy Kable , Thomas Richardson , Brooke Emerling , Erika Lindquist , Mariah Baughn , April Hafalia , Pei Jin , Anita Swarnakar , Joana Li , Joseph Marquis , Ann Gorvad , William Sprague , Shanya Becha , Vicki Elliott
发明人： Narinder Chawla , Soo Lee , Huijun Ring , Ernestine Lee , Ian Forsythe , Reena Khare , Uyen Tran , Amy Kable , Thomas Richardson , Brooke Emerling , Erika Lindquist , Mariah Baughn , April Hafalia , Pei Jin , Anita Swarnakar , Joana Li , Joseph Marquis , Ann Gorvad , William Sprague , Shanya Becha , Vicki Elliott
IPC分类号： A61K38/00 , C07K14/47 , C12N9/00 , C12N15/12 , C12Q1/68 , C07H21/04 , G01N33/53
CPC分类号： C07K14/4702 , A61K38/00 , C12N9/00
摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode-ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.
摘要翻译：本发明的各种实施方案提供了识别和编码ENZM的人类酶（ENZM）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与ENZM异常表达相关的紊乱的方法。

2. 发明申请

US20050176944A1 Intracellular signaling molecules 审中-公开
标题翻译：细胞内信号分子
公开(公告)号：US20050176944A1
公开(公告)日：2005-08-11
申请号：US10487092
申请日：2002-08-16
申请人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号： C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译：本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。

3. 发明申请

US20050107293A1 Protein modification and maintenance molecules 审中-公开
标题翻译：蛋白质修饰和维持分子
公开(公告)号：US20050107293A1
公开(公告)日：2005-05-19
申请号：US10489695
申请日：2002-09-13
申请人： William Sprague , Narinder Chawla , Bridget Warren , Y. Tom Tang , Vicki Elliott , Joseph Marquis , Joana Li , Jennifer Griffin , Kimberly Gietzen , Junming Yang , Dyung Lu , Brooke Emerling , Brendan Duggan , Thomas Richardson , Soo Lee , Jayalaxmi Ramkumar , Shanya Becha , Patricia Mason , Anita Swarnakar , Uyen Tran , Amy Kable , April Hafalia , Reena Khare
发明人： William Sprague , Narinder Chawla , Bridget Warren , Y. Tom Tang , Vicki Elliott , Joseph Marquis , Joana Li , Jennifer Griffin , Kimberly Gietzen , Junming Yang , Dyung Lu , Brooke Emerling , Brendan Duggan , Thomas Richardson , Soo Lee , Jayalaxmi Ramkumar , Shanya Becha , Patricia Mason , Anita Swarnakar , Uyen Tran , Amy Kable , April Hafalia , Reena Khare
IPC分类号： G01N33/53 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/18 , A61P3/00 , A61P5/00 , A61P5/24 , A61P5/38 , A61P9/00 , A61P15/00 , A61P17/00 , A61P25/00 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/06 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/566 , G01N33/577 , G01N37/00 , A61K38/45 , C07H21/04 , C12N9/12
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , C12N9/6421
摘要： Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.
摘要翻译：本发明的各种实施方案提供了识别和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与PMMM异常表达相关的紊乱的方法。

4. 发明申请

US20070124581A1 Cell adhesion and extracellular matrix proteins 审中-公开
公开(公告)号：US20070124581A1
公开(公告)日：2007-05-31
申请号：US10513957
申请日：2003-05-06
申请人： Reena Khare , Vicki Elliott , Joseph Marquis , Jayalaxmi Ramkumar , Narinder Chawla , Patricia Mason , April Hafalia , Anita Swarnakar , Pei Jin , Shanya Becha , Amy Kable , Uyen Tran , Mariah Baughn , Neil Burford , Richard Graul , Brooke Emerling , William Sprague , Jennifer Griffin , Craig Ison
发明人： Reena Khare , Vicki Elliott , Joseph Marquis , Jayalaxmi Ramkumar , Narinder Chawla , Patricia Mason , April Hafalia , Anita Swarnakar , Pei Jin , Shanya Becha , Amy Kable , Uyen Tran , Mariah Baughn , Neil Burford , Richard Graul , Brooke Emerling , William Sprague , Jennifer Griffin , Craig Ison
IPC分类号： H04L9/00
CPC分类号： C07K14/47 , A61K48/00 , G01N33/5014 , G01N2500/04
摘要： Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.

5. 发明申请

US20050123912A1 Nucleic-acid associated proteins 审中-公开
标题翻译：核酸相关蛋白
公开(公告)号：US20050123912A1
公开(公告)日：2005-06-09
申请号：US10486977
申请日：2002-08-14
申请人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
发明人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/16 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/22
CPC分类号： C07K14/4702 , A61K38/00 , G01N2500/00
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译：本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。

6. 发明申请

US20060127894A1 Protein associated with cell growth, differentiation, and death 审中-公开
标题翻译：与细胞生长，分化和死亡相关的蛋白质
公开(公告)号：US20060127894A1
公开(公告)日：2006-06-15
申请号：US10486020
申请日：2002-08-08
申请人： Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
发明人： Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
IPC分类号： C12Q1/68 , G01N33/53 , C07H21/04 , C12P21/06 , C07K14/475 , C07K16/22 , C40B40/10
CPC分类号： C07K14/47 , C07K14/4747 , C07K14/4748 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/6872 , G01N2333/47
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译：本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。

7. 发明申请

US20050186569A1 Nucleic acid-associated proteins 审中-公开
标题翻译：核酸相关蛋白
公开(公告)号：US20050186569A1
公开(公告)日：2005-08-25
申请号：US10491472
申请日：2002-10-29
申请人： Shanya Becha , Mark Borowsky , Neil Burford , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joseph Marquis , Jayalaxmi Ramkumar , William Sprague , Anita Swarnakar , Y. Tang , Bridget Warren , Junming Yang , Henry Yue , Yeganeh Zebarjadian
发明人： Shanya Becha , Mark Borowsky , Neil Burford , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joseph Marquis , Jayalaxmi Ramkumar , William Sprague , Anita Swarnakar , Y. Tang , Bridget Warren , Junming Yang , Henry Yue , Yeganeh Zebarjadian
IPC分类号： C07H21/04 , C07K14/47 , C12N9/22 , C12Q1/68
CPC分类号： C07K14/4702 , C07K14/47
摘要： A Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译：本发明的各种实施方案提供鉴定和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。

8. 发明申请

US20070225218A1 Extracellular Messengers 审中-公开
标题翻译：细胞外信使
公开(公告)号：US20070225218A1
公开(公告)日：2007-09-27
申请号：US10481700
申请日：2002-06-26
申请人： Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
发明人： Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
IPC分类号： C12P21/00 , A61K38/00 , C07H21/04 , C07K14/00 , C12Q1/68 , G01N33/53 , C07K16/18 , C12N15/00 , C12N5/06
CPC分类号： C07K14/47 , A61K38/00
摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
摘要翻译：本发明的各种实施方案提供了识别和编码EXMES的人细胞外信使（EXMES）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其它实施方案提供用于诊断，治疗或预防与异常表达EXMES相关的紊乱的方法。

9. 发明申请

US20060128495A1 Lightweight, durable golf club shafts 有权
标题翻译：轻便耐用的高尔夫球杆轴
公开(公告)号：US20060128495A1
公开(公告)日：2006-06-15
申请号：US11345872
申请日：2006-02-01
申请人： W. Braly , William Sprague
发明人： W. Braly , William Sprague
IPC分类号： A63B53/12
CPC分类号： A63B60/00 , A63B53/12 , A63B2060/0085 , A63B2209/02
摘要： An ultra lightweight golf club shaft which includes a butt section, a tip section, and a tapered section interconnecting the same. The tapered section can be a constant taper, or include a plurality of step portions interconnected by frustoconical transition areas. The shafts are extremely durable and allow a faster club head speed and a better feel than with the previous prior art shafts.
摘要翻译：一种超轻型高尔夫球杆杆，其包括对接部分，尖端部分和与其相互连接的锥形部分。锥形部分可以是恒定的锥形，或者包括通过截头圆锥形过渡区域相互连接的多个台阶部分。这些轴是非常耐用的，并且允许比先前的现有技术的轴更快的球杆头速度和更好的感觉。

10. 发明申请

US20070213847A1 Apparatus for, and method of, positioning an interface unit of an automatic test system 审中-公开
标题翻译：用于定位自动测试系统的接口单元的设备和方法
公开(公告)号：US20070213847A1
公开(公告)日：2007-09-13
申请号：US11366773
申请日：2006-03-01
申请人： William Sprague , Don Chiu , Jerzy Lobacz , Kenneth Karklin
发明人： William Sprague , Don Chiu , Jerzy Lobacz , Kenneth Karklin
IPC分类号： G05B11/01
CPC分类号： G01R31/2887
摘要： There is disclosed a manipulator for positioning an interface of an automatic test system. In an embodiment, the manipulator includes a support device to support the interface. A base portion is in connection to the support device. The base portion includes a rotational adjustment mechanism for moving the support device about an axis of rotation. A planar adjustment mechanism moves the support device within a plane orthogonal to the axis of rotation. There is disclosed a method of positioning an interface unit of an automatic test system. In an embodiment, the method includes moving a support device supporting the interface unit a distance from a docking region of a material handling device; and rotating the support device about an axis of rotation passing through the interface unit. Other embodiments are also disclosed.
摘要翻译：公开了一种用于定位自动测试系统的界面的操纵器。在一个实施例中，所述操纵器包括用于支撑所述界面的支撑装置。基座部分与支撑装置连接。基部包括用于使支撑装置围绕旋转轴线移动的旋转调节机构。平面调节机构使支撑装置在与旋转轴线正交的平面内移动。公开了一种定位自动测试系统的接口单元的方法。在一个实施例中，该方法包括将支撑装置移动到与材料处理装置的对接区域相距一定距离的支撑装置; 并且围绕穿过所述接口单元的旋转轴旋转所述支撑装置。还公开了其他实施例。

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