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1. 发明申请

US20100120172A1 SUBSTANCE WITH ANTITHROMBOTIC ACTIVITY AND METHOD FOR DETECTING GLYCOKALLIDIN 审中-公开
标题翻译：具有抗血小板活性的物质和用于检测谷丙素的方法
公开(公告)号：US20100120172A1
公开(公告)日：2010-05-13
申请号：US12548898
申请日：2009-08-27
申请人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
发明人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
IPC分类号： G01N33/53
CPC分类号： C07K14/705 , C07K14/755 , C07K2317/52 , C07K2319/00 , C07K2319/30 , G01N33/86 , G01N2333/755
摘要： A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.
摘要翻译：一种方便检测血管性血友病因子与糖蛋白Ⅰb之间的结合的方法及其中使用的方法。固定在反应容器中的存在于布可菌素的反应器中的血管性血友病因子结合于通过将含有糖蛋白1b的血管性血友病变因子结合位点的部分蛋白的羧基末端与羧基末端相连的氨基末端免疫球蛋白分子的Fc区。然后检测上述免疫球蛋白分子的Fc区，从而检测血管性血友病因子与糖蛋白Ib之间的结合或抑制该结合。

2. 发明授权

US07608695B2 Substance with antithrombotic activity and method for detecting glycokallidin 失效
标题翻译：具有抗血栓活性的物质和检测糖蛋白的方法
公开(公告)号：US07608695B2
公开(公告)日：2009-10-27
申请号：US10825127
申请日：2004-04-16
申请人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
发明人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
IPC分类号： C12P21/08
CPC分类号： C07K14/705 , C07K14/755 , C07K2317/52 , C07K2319/00 , C07K2319/30 , G01N33/86 , G01N2333/755
摘要： A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.
摘要翻译：一种方便检测血管性血友病因子与糖蛋白Ⅰb之间的结合的方法及其中使用的方法。固定在反应容器中的存在于布可菌素的反应器中的血管性血友病因子结合于通过将含有糖蛋白1b的血管性血友病变因子结合位点的部分蛋白的羧基末端与羧基末端相连的氨基末端免疫球蛋白分子的Fc区。然后检测上述免疫球蛋白分子的Fc区，从而检测血管性血友病因子与糖蛋白Ib之间的结合或抑制该结合。

3. 发明授权

US06878811B1 Substance with antithrombotic activity and method for detecting glycokallidin 失效
标题翻译：具有抗血栓活性的物质和检测糖调素的方法
公开(公告)号：US06878811B1
公开(公告)日：2005-04-12
申请号：US09673245
申请日：1999-01-13
申请人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Koichi Ishii , Akiko Tanaka
发明人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Koichi Ishii , Akiko Tanaka
IPC分类号： C07K14/705 , C07K14/755 , G01N33/86 , C12P21/08 , G01N33/53
CPC分类号： C07K14/705 , C07K14/755 , C07K2317/52 , C07K2319/00 , C07K2319/30 , G01N33/86 , G01N2333/755
摘要： A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.
摘要翻译：一种方便检测血管性血友病因子与糖蛋白Ⅰb之间的结合的方法及其中使用的方法。固定在反应容器中的存在于布可菌素的反应器中的血管性血友病因子结合于通过将含有糖蛋白1b的血管性血友病变因子结合位点的部分蛋白的羧基末端与羧基末端相连的氨基末端免疫球蛋白分子的Fc区。然后检测上述免疫球蛋白分子的Fc区，从而检测血管性血友病因子与糖蛋白Ib之间的结合或抑制该结合。

4. 发明授权

US5856126A Peptide having anti-thrombus activity and method of producing the same 失效
标题翻译：具有抗血栓活性的肽及其制备方法
公开(公告)号：US5856126A
公开(公告)日：1999-01-05
申请号：US612840
申请日：1996-03-20
申请人： Naoyuki Fukuchi , Hiroshi Yamamoto , Mitsuyo Nagano , Morikazu Kito , Akiko Tanaka , Koichi Ishii , Tsuyoshi Kobayashi , Ryota Yoshimoto
发明人： Naoyuki Fukuchi , Hiroshi Yamamoto , Mitsuyo Nagano , Morikazu Kito , Akiko Tanaka , Koichi Ishii , Tsuyoshi Kobayashi , Ryota Yoshimoto
IPC分类号： A61K38/00 , A61P7/02 , C07K14/46 , C12N15/12 , C07K14/435 , A61K38/16
CPC分类号： C07K14/46 , A61K38/00 , C12N2799/026 , Y10S514/822 , Y10S530/856
摘要： A multimer peptide from a snake venom has an activity to inhibit binding between von Willebrand factor and platelets. The multimer peptide is used to obtain a single strand peptide which does not substantially cause decrease in platelets at a minimum dose for exhibiting the activity in vivo. The single strand peptide is obtained by allowing the multimer peptide to exist together with a protein-denaturing agent, and glutathione and/or cysteine, and thereby disconnecting disulfide bonds between peptide chains for constituting the multimer peptide while substantially preserving disulfide bonds within the peptide chains. Alternatively, the single strand peptide, a mutant thereof, or a part thereof is produced by genetic engineering techniques by using genes coding for them.
摘要翻译： PCT No.PCT / JP94 / 01555 Sec。 371日期：1996年3月20日 102（e）1996年3月20日PCT 1994年9月21日PCT PCT。公开号WO95 / 08573 日期1995年3月30日蛇毒的多聚体肽具有抑制血管性血友病因子与血小板结合的活性。多聚体肽用于获得单链肽，其基本上不以最小剂量引起血小板减少以显示体内活性。通过使多聚体肽与蛋白质变性剂，谷胱甘肽和/或半胱氨酸一起存在，从而在构成多聚体肽的肽链之间断开二硫键，同时基本上保留肽链内的二硫键，获得单链肽。或者，单链肽，其突变体或其一部分通过使用编码它们的基因的遗传工程技术产生。

5. 发明授权

US08415622B2 Infrared imaging element 有权
标题翻译：红外成像元件
公开(公告)号：US08415622B2
公开(公告)日：2013-04-09
申请号：US13414941
申请日：2012-03-08
申请人： Kazuhiro Suzuki , Hiroto Honda , Ikuo Fujiwara , Hideyuki Funaki , Hitoshi Yagi , Keita Sasaki , Honam Kwon , Koichi Ishii , Masako Ogata , Risako Ueno
发明人： Kazuhiro Suzuki , Hiroto Honda , Ikuo Fujiwara , Hideyuki Funaki , Hitoshi Yagi , Keita Sasaki , Honam Kwon , Koichi Ishii , Masako Ogata , Risako Ueno
IPC分类号： H01L25/00
CPC分类号： H01L27/14618 , G01J5/024 , H01L27/1461 , H01L27/14636 , H01L27/1464 , H01L27/14649 , H01L2924/0002 , H01L2924/00
摘要： An infrared imaging element according to an embodiment includes: a semiconductor substrate including a stacked structure of a silicon first substrate, and a first insulation film, first cavities being provided on a surface of the first substrate; an infrared detection unit provided in the semiconductor substrate and including, detection cells provided respectively over the first cavities, each of the detection cells having diodes and a second insulation film, the first insulation film converting incident infrared rays to heat, the diodes converting the heat obtained by the first insulation film to an electric signal, a third insulation film having a top face located at a greater distance from the semiconductor substrate as compared with a top face of the second insulation film; and a second substrate provided over the third insulation film. A second cavity is formed between the second substrate and the infrared detection unit.
摘要翻译：根据实施例的红外成像元件包括：包括硅第一基板的堆叠结构的半导体基板和第一绝缘膜，在第一基板的表面上设置有第一空腔; 红外线检测单元，设置在所述半导体基板中，并且包括分别设置在所述第一空腔上的检测单元，每个所述检测单元具有二极管和第二绝缘膜，所述第一绝缘膜将入射红外线转换成加热，由所述第一绝缘膜获得的电信号;第三绝缘膜，其具有与所述第二绝缘膜的顶面相比位于距所述半导体基板更远的距离的顶面; 以及设置在所述第三绝缘膜上的第二基板。在第二基板和红外线检测单元之间形成第二空腔。

6. 发明申请

US20120228497A1 INFRARED IMAGING ELEMENT 有权
标题翻译：红外成像元件
公开(公告)号：US20120228497A1
公开(公告)日：2012-09-13
申请号：US13414941
申请日：2012-03-08
申请人： Kazuhiro SUZUKI , Hiroto Honda , Ikuo Fujiwara , Hideyuki Funaki , Hitoshi Yagi , Keita Sasaki , Honam Kwon , Koichi Ishii , Masako Ogata , Risako Ueno
发明人： Kazuhiro SUZUKI , Hiroto Honda , Ikuo Fujiwara , Hideyuki Funaki , Hitoshi Yagi , Keita Sasaki , Honam Kwon , Koichi Ishii , Masako Ogata , Risako Ueno
IPC分类号： H01L27/146
CPC分类号： H01L27/14618 , G01J5/024 , H01L27/1461 , H01L27/14636 , H01L27/1464 , H01L27/14649 , H01L2924/0002 , H01L2924/00
摘要： An infrared imaging element according to an embodiment includes: a semiconductor substrate including a stacked structure of a silicon first substrate, and a first insulation film, first cavities being provided on a surface of the first substrate; an infrared detection unit provided in the semiconductor substrate and including, detection cells provided respectively over the first cavities, each of the detection cells having diodes and a second insulation film, the first insulation film converting incident infrared rays to heat, the diodes converting the heat obtained by the first insulation film to an electric signal, a third insulation film having a top face located at a greater distance from the semiconductor substrate as compared with a top face of the second insulation film; and a second substrate provided over the third insulation film. A second cavity is formed between the second substrate and the infrared detection unit.
摘要翻译：根据实施例的红外成像元件包括：包括硅第一基板的堆叠结构的半导体基板和第一绝缘膜，在第一基板的表面上设置有第一空腔; 红外线检测单元，设置在所述半导体基板中，并且包括分别设置在所述第一空腔上的检测单元，每个所述检测单元具有二极管和第二绝缘膜，所述第一绝缘膜将入射红外线转换成加热，由所述第一绝缘膜获得的电信号;第三绝缘膜，其具有与所述第二绝缘膜的顶面相比位于距所述半导体基板更远的距离的顶面; 以及设置在所述第三绝缘膜上的第二基板。在第二基板和红外线检测单元之间形成第二空腔。

7. 发明申请

US20120228496A1 UNCOOLED INFRARED IMAGING ELEMENT AND MANUFACTURING METHOD THEREOF 有权
标题翻译：未经处理的红外成像元件及其制造方法
公开(公告)号：US20120228496A1
公开(公告)日：2012-09-13
申请号：US13235388
申请日：2011-09-18
申请人： Masako OGATA , Ikuo Fujiwara , Hiroto Honda , Kazuhiro Suzuki , Honam Kwon , Risako Ueno , Hitoshi Yagi , Masaki Atsuta , Koichi Ishii , Keita Sasaki , Hideyuki Funaki
发明人： Masako OGATA , Ikuo Fujiwara , Hiroto Honda , Kazuhiro Suzuki , Honam Kwon , Risako Ueno , Hitoshi Yagi , Masaki Atsuta , Koichi Ishii , Keita Sasaki , Hideyuki Funaki
IPC分类号： H01L27/146 , H01L31/18
CPC分类号： H01L27/14649 , H01L27/14632 , H01L27/14687
摘要： An uncooled infrared imaging element includes a pixel region, a device region, and a support substrate. The pixel region includes heat-sensitive pixels. The heat-sensitive pixels are arranged in a matrix and change current-voltage characteristics thereof in accordance with receiving amounts of infrared. The device region includes at least one of a drive circuit and a readout circuit which includes a MOS transistor. The drive circuit drives the heat-sensitive pixels. The readout circuit detects signals of the heat-sensitive pixels. The support substrate is provided with a cavity region to be under pixel region and the MOS transistor.
摘要翻译：非制冷红外成像元件包括像素区域，器件区域和支撑衬底。像素区域包括热敏像素。热敏像素被布置成矩阵并且根据接收到的红外线量来改变其电流 - 电压特性。器件区域包括驱动电路和包括MOS晶体管的读出电路中的至少一个。驱动电路驱动热敏像素。读出电路检测热敏像素的信号。支撑基板设置有在像素区域下方的空腔区域和MOS晶体管。

8. 发明申请

US20120056291A1 IMAGING DEVICE, IMAGING MODULE AND METHOD FOR MANUFACTURING IMAGING DEVICE 有权
标题翻译：成像装置，成像模块和制造成像装置的方法
公开(公告)号：US20120056291A1
公开(公告)日：2012-03-08
申请号：US13051413
申请日：2011-03-18
申请人： Kazuhiro Suzuki , Risako Ueno , Honam Kwon , Koichi Ishii , Hideyuki Funaki
发明人： Kazuhiro Suzuki , Risako Ueno , Honam Kwon , Koichi Ishii , Hideyuki Funaki
IPC分类号： H01L27/146 , H01L31/18
CPC分类号： H01L27/14618 , H01L27/14649 , H01L2224/13
摘要： According to one embodiment, an imaging device includes a substrate, a photodetecting portion, a circuit portion and a through interconnect. The substrate has a first major surface, a second major surface on a side opposite to the first major surface, a recess portion provided on the first major surface and retreated in a first direction going from the first major surface to the second major surface, and a through hole communicating with the first major surface and the second major surface and extending in the first direction. The photodetecting portion is provided above the recess portion and away from the substrate. The circuit portion is electrically connected to the photodetecting portion and provided on the first major surface. The through interconnect is electrically connected to the circuit portion and provided inside the through hole. The recess portion has a first inclined surface. The through hole has a second inclined surface.
摘要翻译：根据一个实施例，成像装置包括基板，光电检测部分，电路部分和通孔互连。基板具有第一主表面，与第一主表面相对的一侧的第二主表面，设置在第一主表面上并沿着从第一主表面到第二主表面的第一方向退回的凹部，以及与所述第一主表面和所述第二主表面连通并且沿所述第一方向延伸的通孔。光电检测部分设置在凹部的上方并远离基板。电路部分电连接到光电检测部分并设置在第一主表面上。通孔互连电连接到电路部分并设置在通孔的内部。凹部具有第一倾斜面。通孔具有第二倾斜面。

9. 发明授权

US07648813B2 Pattern forming method 失效
标题翻译：图案形成方法
公开(公告)号：US07648813B2
公开(公告)日：2010-01-19
申请号：US12268699
申请日：2008-11-11
申请人： Mitsunaga Saito , Yasushi Shinjiyo , Yoshihiro Tajima , Koichi Ishii , Masahiro Hosoya , Ken Takahashi
发明人： Mitsunaga Saito , Yasushi Shinjiyo , Yoshihiro Tajima , Koichi Ishii , Masahiro Hosoya , Ken Takahashi
IPC分类号： G03G13/045
CPC分类号： G02B5/201 , H05K3/207 , H05K2203/0113 , H05K2203/105 , H05K2203/1142
摘要： By using an intaglio plate for holding a pattern formed by a developing agent, a transfer device for transferring patterns developed on the intaglio plate to a transfer object medium, and a baking chamber for eliminating an electrode layer after transfer or heightening resistance thereof, the patterns developed on the intaglio plate are transferred onto the electrode layer disposed at the opposite side of the transfer object medium, and then heated in the baking chamber, whereby the electrode layer is eliminated or heightened in resistance.
摘要翻译：通过使用用于保持由显影剂形成的图案的凹版，用于将在凹版上显影的图案转印到转印体介质上的转印装置，以及用于在转印或增强电阻之后消除电极层的烘烤室，在凹版上显影的图案转印到设置在转印体介质相反侧的电极层上，然后在烘烤室中加热，从而电极层被消除或提高。

10. 发明授权

US07646578B2 Filter circuit and filter device 有权
标题翻译：滤波电路和滤波器
公开(公告)号：US07646578B2
公开(公告)日：2010-01-12
申请号：US11785211
申请日：2007-04-16
申请人： Yuji Terada , Dai Matsuoka , Koichi Ishii
发明人： Yuji Terada , Dai Matsuoka , Koichi Ishii
IPC分类号： H02H1/00 , H02H3/22
CPC分类号： H03H7/0107 , H03H2001/0085
摘要： A filter circuit has first and second varistors, a resistance, an input terminal, an output terminal, and a ground terminal. The resistance is connected between the first and second varistors. The input terminal is connected to a junction between the first varistor and resistance through a first coil. The output terminal is connected to a junction between the second varistor and resistance through a second coil. The ground terminal is connected to a side of the first varistor opposite from the resistance and a side of the second varistor opposite from the resistance.
摘要翻译：滤波器电路具有第一和第二变阻器，电阻，输入端子，输出端子和接地端子。电阻连接在第一和第二变阻器之间。输入端子通过第一线圈连接到第一变阻器和电阻之间的接点。输出端子通过第二线圈连接到第二压敏电阻和电阻之间的结。接地端子与第一变阻器的与电阻相反的一侧连接，第二变阻器的与电阻相反的一侧连接。

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