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1. 发明授权

US07714398B2 Nanoelectronic measurement system for physiologic gases and improved nanosensor for carbon dioxide 有权
标题翻译：用于生理气体的纳米电子测量系统和改进的二氧化碳纳米传感器
公开(公告)号：US07714398B2
公开(公告)日：2010-05-11
申请号：US11390493
申请日：2006-03-27
申请人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
发明人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
IPC分类号： G01N27/414
CPC分类号： G01N33/5438 , A61B5/073 , A61B2562/0285 , B82Y10/00 , B82Y15/00 , B82Y20/00 , H01L51/0048 , H01L51/0052 , H01L51/0545
摘要： A system for measuring an analyte of interest, particularly carbon dioxide, dissolved in a fluid media of a patient including a nanoelectronic sensor and a measurement instrument in communication with the sensor and configured to receive at least a signal from the sensor indicative of a response of the sensor to at least the analyte of interest.
摘要翻译：一种用于测量感兴趣的分析物，特别是二氧化碳的系统，其溶解在患者的流体介质中，包括与所述传感器通信的纳米电子传感器和测量仪器，并且被配置为从所述传感器接收表示响应的信号传感器至少是所关注的分析物。

2. 发明申请

US20100056892A1 NANOELECTRONIC MEASUREMENT SYSTEM FOR PHYSIOLOGIC GASES AND IMPROVED NANOSENSOR FOR CARBON DIOXIDE 有权
标题翻译：用于生物气体的纳米电子测量系统和改进的二氧化碳纳米传感器
公开(公告)号：US20100056892A1
公开(公告)日：2010-03-04
申请号：US11390493
申请日：2006-03-27
申请人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
发明人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
IPC分类号： A61B5/05 , A61N1/36
CPC分类号： G01N33/5438 , A61B5/073 , A61B2562/0285 , B82Y10/00 , B82Y15/00 , B82Y20/00 , H01L51/0048 , H01L51/0052 , H01L51/0545
摘要： A system for measuring an analyte of interest, particularly carbon dioxide, dissolved in a fluid media of a patient including a nanoelectronic sensor and a measurement instrument in communication with the sensor and configured to receive at least a signal from the sensor indicative of a response of the sensor to at least the analyte of interest.
摘要翻译：一种用于测量感兴趣的分析物，特别是二氧化碳的系统，其溶解在患者的流体介质中，包括与所述传感器通信的纳米电子传感器和测量仪器，并且被配置为从所述传感器接收表示响应的信号传感器至少是所关注的分析物。

3. 发明申请

US20100085067A1 ANESTHESIA MONITOR, CAPACITANCE NANOSENSORS AND DYNAMIC SENSOR SAMPLING METHOD 审中-公开
标题翻译：麻醉监护仪，电容式纳米传感器和动态传感器采样方法
公开(公告)号：US20100085067A1
公开(公告)日：2010-04-08
申请号：US12560316
申请日：2009-09-15
申请人： Jean-Christophe P. Gabriel , Vikram Joshi , John Loren Passmore , Sergei Skarupo , Alexander Star , Christian Valcke
发明人： Jean-Christophe P. Gabriel , Vikram Joshi , John Loren Passmore , Sergei Skarupo , Alexander Star , Christian Valcke
IPC分类号： G01N33/497 , G01N27/22 , A61B5/08 , A61B5/05
CPC分类号： A61B5/0833 , A61B5/097 , A61B5/4821 , A61B5/6819 , A61B2562/0285 , B82Y30/00
摘要： Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such as anesthesia gases, CO2 and the like in human breath. An integrated monitor system and disposable sensor unit is described which permits a number of different anesthetic agents to be identified and monitored, as well as concurrent monitoring of other breath species, such as CO2. The sensor unit may be configured to be compact, light weight, and inexpensive. Wireless embodiments provide such enhancements as remote monitoring. A simulator system for modeling the contents and conditions of human inhalation and exhalation with a selected mixture of a treatment agent is also described, particularly suited to the testing of sensors to be used in airway sampling.
摘要翻译：描述了纳米电子传感器的实施例，包括用于在人呼吸中检测分析物例如麻醉气体，CO 2等的传感器。描述了一种集成监视器系统和一次性传感器单元，其允许识别和监视多个不同的麻醉剂，以及对其它呼吸物质（例如CO 2）的并发监测。传感器单元可以被配置为紧凑，重量轻并且便宜。无线实施例提供诸如远程监视的增强。还描述了一种用于用选定的处理剂混合物对人吸入和呼出的内容物和条件进行建模的模拟器系统，特别适合于用于气道取样的传感器的测试。

4. 发明授权

US08152991B2 Ammonia nanosensors, and environmental control system 有权
标题翻译：氨纳米传感器和环境控制系统
公开(公告)号：US08152991B2
公开(公告)日：2012-04-10
申请号：US11636360
申请日：2006-12-08
申请人： Mikhail Briman , Craig Bryant , Ying-Lan Chang , Jean-Christophe P. Gabriel , Shirpal C. Gandhi , Bradley N Johnson , Willem-Jan Ouborg , John Loren Passmore , Kastooriranganathan Ramakrishnan , Sergei Skarupo , Alexander Star , Christian Valcke
发明人： Mikhail Briman , Craig Bryant , Ying-Lan Chang , Jean-Christophe P. Gabriel , Shirpal C. Gandhi , Bradley N Johnson , Willem-Jan Ouborg , John Loren Passmore , Kastooriranganathan Ramakrishnan , Sergei Skarupo , Alexander Star , Christian Valcke
IPC分类号： G01N27/26
CPC分类号： G01N33/0054 , B82Y15/00 , G01N27/127 , G01N27/129 , G01N27/4146 , G01N33/0062 , G01N2033/0068 , H01L29/0669 , Y10S977/957
摘要： Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such ammonia. An environmental control system employing nanoelectronic sensors is described. A personnel safety system configured as a disposable badge employing nanoelectronic sensors is described. A method of dynamic sampling and exposure of a sensor providing a number of operational advantages is described.
摘要翻译：描述了纳米电子传感器的实施例，包括用于检测分析物这种氨的传感器。描述了采用纳米电子传感器的环境控制系统。描述了配置为使用纳米电子传感器的一次性标签的人员安全系统。描述了提供多个操作优点的传感器的动态采样和曝光的方法。

5. 发明申请

US20100047901A1 SYSTEM AND METHOD FOR ELECTRONIC SENSING OF BIOMOLECULES 审中-公开
标题翻译：电子感应生物分子的系统和方法
公开(公告)号：US20100047901A1
公开(公告)日：2010-02-25
申请号：US12607912
申请日：2009-10-28
申请人： Keith Bradley , Jean-Christophe P. Gabriel , George Grüner , Alexander Star , Eugene Tu , Christian Valcke
发明人： Keith Bradley , Jean-Christophe P. Gabriel , George Grüner , Alexander Star , Eugene Tu , Christian Valcke
IPC分类号： G01N33/53
CPC分类号： B82Y30/00 , B01L3/50857 , B01L2300/0636 , B01L2300/0663 , B01L2300/0819 , B01L2300/0851 , B01L2300/0893 , B01L2300/0896 , B01L2300/16 , B82Y10/00 , G01N33/5438 , G01N33/551 , G01N33/566 , G01N33/582
摘要： A nanoelectronic device is combined with a cellular membrane component to provide a sensor for biomolecules or to provide information about the structure of the membrane. The nanoelectronic device may comprise a network of randomly-oriented nanotubes, or other nanostructure, arranged on a substrate with adjacent electrodes so as to operate as a field-effect transistor sensor or as a capacitive sensor. A cellular membrane is disposed over the nanostructure element.
摘要翻译：纳米电子器件与细胞膜组件组合以提供用于生物分子的传感器或提供关于膜结构的信息。纳米电子器件可以包括布置在具有相邻电极的衬底上的随机取向的纳米管或其他纳米结构的网络，以便作为场效应晶体管传感器或电容式传感器工作。细胞膜设置在纳米结构元件上。

6. 发明申请

US20130075690A1 Ammonia Nanosensors, and Environmental Control System 审中-公开
标题翻译：氨氮传感器和环境控制系统
公开(公告)号：US20130075690A1
公开(公告)日：2013-03-28
申请号：US13442720
申请日：2012-04-09
申请人： Mikhail Briman , Craig Bryant , Ying-Lan Chang , Jean-Christophe P. Gabriel , Shripal C. Gandhi , Bradley N. Johnson , Willem-Jan Ouborg , John Loren Passmore , Kastooriranganathan Ramakrishnan , Sergei Skarupo , Alexander Star , Christian Valcke
发明人： Mikhail Briman , Craig Bryant , Ying-Lan Chang , Jean-Christophe P. Gabriel , Shripal C. Gandhi , Bradley N. Johnson , Willem-Jan Ouborg , John Loren Passmore , Kastooriranganathan Ramakrishnan , Sergei Skarupo , Alexander Star , Christian Valcke
IPC分类号： H01L29/06
CPC分类号： G01N33/0054 , B82Y15/00 , G01N27/127 , G01N27/129 , G01N27/4146 , G01N33/0062 , G01N2033/0068 , H01L29/0669 , Y10S977/957
摘要： Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such ammonia. An environmental control system employing nanoelectronic sensors is described. A personnel safety system configured as a disposable badge employing nanoelectronic sensors is described. A method of dynamic sampling and exposure of a sensor providing a number of operational advantages is described.
摘要翻译：描述了纳米电子传感器的实施例，包括用于检测分析物这种氨的传感器。描述了采用纳米电子传感器的环境控制系统。描述了配置为使用纳米电子传感器的一次性标签的人员安全系统。描述了提供多个操作优点的传感器的动态采样和曝光的方法。

7. 发明申请

US20100323925A1 Nanosensor array for electronic olfaction 审中-公开
标题翻译：用于电子嗅觉的纳米传感器阵列
公开(公告)号：US20100323925A1
公开(公告)日：2010-12-23
申请号：US11541794
申请日：2006-10-02
申请人： Jean-Christophe P. Gabriel , Vikram Joshi , Sergei Skarupo , Alexander Star , David Thomas
发明人： Jean-Christophe P. Gabriel , Vikram Joshi , Sergei Skarupo , Alexander Star , David Thomas
IPC分类号： C40B60/12
CPC分类号： B82Y30/00 , B82Y15/00 , G01N27/4146
摘要： A detector system is described including arrays having a plurality of nanoelectronic sensors comprising a channel including a nanostructured element disposed on a substrate, the nanostructured element functionalized by one or more materials disposed on or adjacent to the nanostructured element so as to operatively influence one or more sensor electrical properties. In certain embodiments, the nanostructured element comprise one or more nanotubes, and the functionalization material may include nanoparticles composed of one or more metals, metal oxides, salts, or other inorganic or organic materials or composites of these.In one exemplary embodiment, an array includes plurality of sensors which are configured as field effect transistors, the nanostructured element comprising a randomly dispersed interconnecting network of single-walled carbon nanotubes (SWNTs) having semiconducting properties, and functionalized by deposition of metallic nanoparticles comprising one or more metallic elements. The deposition of nanoparticles may be controlled to preserve semiconductive properties of the nanotubes. Novel methods of electrodeposition of such nanoparticles are described.The detector system may be configured to distinguish and detect a range of different analyte species by measurement of the responses of a plurality of sensors of the array, and analyzing the measurements using principal component analysis, pattern-recognition analysis tools, and the like. Example analytes may comprise a plurality of organic and inorganic gases, such as are relevant to medical, industrial, environmental and security detection.
摘要翻译：描述了一种检测器系统，其包括具有多个纳米电子传感器的阵列，该多个纳米电子传感器包括通道，该通道包括设置在基底上的纳米结构元件，该纳米结构元件由设置在纳米结构元件上或其上的一种或多种材料功能化，以便可操作地影响一个或多个传感器电气特性。在某些实施方案中，纳米结构元件包含一个或多个纳米管，并且官能化材料可以包括由一种或多种金属，金属氧化物，盐或其它无机或有机材料或这些的复合材料组成的纳米颗粒。在一个示例性实施例中，阵列包括配置为场效应晶体管的多个传感器，纳米结构元件包括具有半导体性质的单壁碳纳米管（SWNT）的随机分散的互连网络，并且通过沉积包含一个或更多的金属元素。可以控制纳米颗粒的沉积以保持纳米管的半导体性质。描述了这种纳米颗粒的电沉积的新方法。检测器系统可以被配置为通过测量阵列的多个传感器的响应并且使用主成分分析，模式识别分析工具等分析测量来区分和检测不同分析物种的范围。示例性分析物可以包括多种有机和无机气体，例如与医疗，工业，环境和安全性检测相关的。

8. 发明申请

US20090101996A1 NANOSTRUCTURES WITH ELECTRODEPOSITED NANOPARTICLES 审中-公开
标题翻译：具有电沉积纳米颗粒的纳米结构
公开(公告)号：US20090101996A1
公开(公告)日：2009-04-23
申请号：US12268327
申请日：2008-11-10
申请人： Keith BRADLEY , Alona J. Davis , Jean-Christophe P. Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
发明人： Keith BRADLEY , Alona J. Davis , Jean-Christophe P. Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
IPC分类号： G01N27/403 , H01L21/288
CPC分类号： B82Y30/00 , C25D3/12 , C25D3/46 , C25D3/48 , C25D3/50 , C25D5/02 , C25D5/10 , C25D5/54 , C25D17/005 , C25D21/12 , G01N27/4146 , G01N33/005 , Y10S977/72
摘要： A nanoelectronic device includes a nanostructure, such as a nanotube or network of nanotube, disposed on a substrate. Nanoparticles are disposed on or adjacent to the nanostructure so as to operatively effect the electrical properties of the nanostructure. The nanoparticles may be composed of metals, metal oxides or salts and nanoparticles composed of different materials may be present. The amount of nanoparticles may be controlled to preserve semiconductive properties of the nanostructure, and the substrate immediately adjacent to the nanostructure may remain substantially free of nanoparticles. A method for fabricating the device includes electrodeposition of the nanoparticles using one of more solutions of dissolved ions while providing an electric current to the nanostructures but not to the surrounding substrate.
摘要翻译：纳米电子器件包括纳米结构，例如纳米管或纳米管网络，其设置在衬底上。将纳米颗粒设置在纳米结构上或与纳米结构相邻，以便有效地影响纳米结构的电性能。纳米颗粒可以由金属，金属氧化物或盐组成，并且可以存在由不同材料组成的纳米颗粒。可以控制纳米颗粒的量以保持纳米结构的半导体性质，并且紧邻纳米结构的衬底可以基本上不含纳米颗粒。制造该器件的方法包括使用溶解离子的更多溶液中的一种电解沉积纳米颗粒，同时向纳米结构提供电流，但不向周围衬底提供电流。

9. 发明授权

US07522040B2 Remotely communicating, battery-powered nanostructure sensor devices 有权
标题翻译：远程通信，电池供电的纳米结构传感器设备
公开(公告)号：US07522040B2
公开(公告)日：2009-04-21
申请号：US11111121
申请日：2005-04-20
申请人： John Loren Passmore , Jean-Christophe P. Gabriel , Alexander Star , Vikram Joshi , Sergei Skarupo
发明人： John Loren Passmore , Jean-Christophe P. Gabriel , Alexander Star , Vikram Joshi , Sergei Skarupo
IPC分类号： G08B21/00
CPC分类号： G01N27/4146 , B82Y15/00 , G01N27/4141
摘要： A portable sensor device incorporates a low-power, nanostructure sensor coupled to a wireless transmitter. The sensor uses a nanostructure conducting channel, such as a nanotube network, that is functionalized to respond to a selected analyte. A measurement circuit connected to the sensor determines a change in the electrical characteristic of the sensor, from which information concerning the present or absence of the analyte may be determined. The portable sensor device may include a portable power source, such as a battery. It may further include a transmitter for wirelessly transmitting data to a base station.
摘要翻译：便携式传感器装置包括耦合到无线发射器的低功率纳米结构传感器。传感器使用纳米结构导电通道，例如纳米管网络，其被功能化以响应于所选择的分析物。连接到传感器的测量电路确定传感器的电特性的变化，从该信号可以确定与分析物的存在或不存在有关的信息。便携式传感器装置可以包括诸如电池的便携式电源。它还可以包括用于向基站无线发送数据的发射机。

10. 发明授权

US07449757B2 Nanostructures with electrodeposited nanoparticles 有权
标题翻译：具有电沉积纳米粒子的纳米结构
公开(公告)号：US07449757B2
公开(公告)日：2008-11-11
申请号：US10945803
申请日：2004-09-20
申请人： Keith Bradley , Alona J. Davis , Jean-Christophe P. Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
发明人： Keith Bradley , Alona J. Davis , Jean-Christophe P. Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
IPC分类号： G01N27/403
CPC分类号： B82Y30/00 , G01N27/4146 , G01N33/005 , Y10S977/72
摘要： A nanoelectronic device includes a nanostructure, such as a nanotube or network of nanotubes, disposed on a substrate. Nanoparticles are disposed on or adjacent to the nanostructure so as to operatively effect the electrical properties of the nanostructure. The nanoparticles may be composed of metals, metal oxides, or salts, and nanoparticles composed of different materials may be present. The amount of nanoparticles may be controlled to preserve semiconductive properties of the nanostructure, and the substrate immediately adjacent to the nanostructure may remain substantially free of nanoparticles. A method for fabricating the device includes electrodeposition of the nanoparticles using one or more solutions of dissolved ions while providing an electric current to the nanostructures but not to the surrounding substrate.
摘要翻译：纳米电子器件包括设置在衬底上的纳米结构，例如纳米管或纳米管网络。将纳米颗粒设置在纳米结构上或与纳米结构相邻，以便有效地影响纳米结构的电性能。纳米颗粒可以由金属，金属氧化物或盐组成，并且可以存在由不同材料组成的纳米颗粒。可以控制纳米颗粒的量以保持纳米结构的半导体性质，并且紧邻纳米结构的衬底可以基本上不含纳米颗粒。制造该器件的方法包括使用一种或多种溶解离子的溶液电沉积纳米颗粒，同时向纳米结构提供电流，而不向周围的衬底提供电流。

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