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1. 发明授权

US09864028B2 PET-MRI apparatus 有权
公开(公告)号：US09864028B2
公开(公告)日：2018-01-09
申请号：US13873706
申请日：2013-04-30
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES , TOSHIBA MEDICAL SYSTEMS CORPORATION
发明人： Iwao Kanno , Takayuki Obata , Taiga Yamaya , Kazuya Okamoto , Takuzo Takayama , Hitoshi Yamagata
IPC分类号： G01R33/422 , A61B5/055 , A61B6/03 , A61B6/00 , G01R33/48 , G01T1/16 , A61B5/00
CPC分类号： G01R33/422 , A61B5/0035 , A61B5/055 , A61B6/037 , A61B6/4417 , A61B6/5235 , A61B6/5247 , G01R33/481 , G01T1/1603
摘要： In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a transmitting radio frequency coil applies a radio frequency magnetic field on a subject placed in a static magnetic field. A detector is formed in a ring shape, disposed on a side adjacent to an outer circumference of the transmitting radio frequency coil, includes at least two PET detectors disposed with a space therebetween in an axial direction of a bore so as to interpose the magnetic field center of the static magnetic field therebetween, and detects gamma rays emitted from positron emitting radionuclides injected into the subject. Radio frequency shields are each formed in an approximately cylindrical shape, disposed between the transmitting radio frequency coil and the detector, and shield the radio frequency magnetic field generated by the transmitting radio frequency coil.

2. 发明授权

US09880236B2 PET-MRI apparatus 有权
公开(公告)号：US09880236B2
公开(公告)日：2018-01-30
申请号：US13874795
申请日：2013-05-01
申请人： National Institute of Radiological Sciences , Toshiba Medical Systems Corporation
发明人： Takayuki Obata , Taiga Yamaya , Iwao Kanno , Hitoshi Yamagata , Takuzo Takayama , Kazuya Okamoto
IPC分类号： G01R33/28 , A61B6/03 , A61B6/00 , G01R33/48 , G01T1/16 , A61B5/00 , A61B5/055
CPC分类号： G01R33/28 , A61B5/0035 , A61B5/055 , A61B6/037 , A61B6/4417 , G01R33/481 , G01T1/1603
摘要： In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a magnet that is a seamless structure generates a static magnetic field in a bore having a cylindrical shape. First detectors and second detectors are each formed in a ring shape and detect gamma rays emitted from positron emitting radionuclides injected into a subject. The first detectors and the second detectors are disposed with a space therebetween in an axial direction of the bore so as to interpose the magnetic field center of the static magnetic field therebetween.

3. 发明申请

US20150117736A1 METHOD FOR GENERATING IMAGE FOR PET ATTENUATION CORRECTION FROM MR IMAGE AND COMPUTER PROGRAM 有权
标题翻译：用于从MR图像和计算机程序生成用于PET衰减校正的图像的方法
公开(公告)号：US20150117736A1
公开(公告)日：2015-04-30
申请号：US14385683
申请日：2013-03-28
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES , SHIMADZU CORPORATION
发明人： Taiga Yamaya , Takayuki Obata , Mikio Suga , Hiroshi Kawaguchi , Yoshiyuki Yamakawa
IPC分类号： G06T11/00 , A61B5/00
CPC分类号： G06T11/005 , A61B5/0035 , A61B5/055 , A61B6/037 , A61B2576/026 , G01R33/481 , G01T1/1603 , G06T7/11 , G06T2207/10088 , G06T2207/10104 , G06T2207/30004
摘要： When an image for PET attenuation correction is generated from an MR image, the MR image captured by MRI is segmented into regions according to pixel values. In a region in which a radiation attenuation coefficient is considered to be uniform, a radiation attenuation correction value is determined by referring to an existing radiation attenuation correction value table. In a region including multiple tissues having different radiation attenuation coefficients, a radiation attenuation correction value is determined by referring to a standard image. In such a manner, an image for PET attenuation correction in which tissues having similar pixel values in the MR image but different attenuation coefficients for radiation can be distinguished and that can accommodate individual differences and an affected area such as a space occupying lesion (for example, a cancer, abscess, or the like) and an organic defect is generated.
摘要翻译：当从MR图像产生用于PET衰减校正的图像时，由MRI捕获的MR图像根据像素值被分割成区域。在辐射衰减系数被认为是均匀的区域中，通过参照现有的辐射衰减校正值表确定辐射衰减校正值。在包括具有不同辐射衰减系数的多个组织的区域中，通过参考标准图像来确定辐射衰减校正值。以这种方式，用于PET衰减校正的图像，其中可以区分在MR图像中具有相似像素值但是具有不同的辐射衰减系数的组织，并且可以适应个体差异和诸如空间占据病变的受影响区域（例如，，癌症，脓肿等），产生有机缺陷。

4. 发明授权

US09226717B2 Helmet-type PET device 有权
标题翻译：头盔型PET装置
公开(公告)号：US09226717B2
公开(公告)日：2016-01-05
申请号：US14495543
申请日：2014-09-24
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES
发明人： Hideaki Tashima , Taiga Yamaya
IPC分类号： G01T1/20 , A61B6/03 , A61B6/00 , A61B6/04
CPC分类号： A61B6/037 , A61B6/0478 , A61B6/501
摘要： A helmet-type PET device includes a helmet portion (hemispherical detector) and an added portion (jaw portion detector, an ear portion detector, or a neck portion detector). The helmet portion includes a PET detector so as to cover a parietal region of an examination target. The added portion is positioned to dispose a PET detector at a part other than the parietal region of the examination target. PET measurement is performed using both an output from the PET detector at the helmet portion and an output from the PET detector at the added portion.
摘要翻译：头盔式PET装置包括头盔部分（半球形检测器）和附加部分（颚部检测器，耳部检测器或颈部检测器）。头盔部分包括PET检测器，以覆盖检查对象的顶叶区域。所添加的部分定位成在检查对象的顶叶区域之外的部分处设置PET检测器。使用头盔部分的PET检测器的输出和来自PET检测器的添加部分的输出进行PET测量。

5. 发明授权

US09342903B2 Method for generating image for PET attenuation correction from MR image and computer program 有权
标题翻译：用于从MR图像和计算机程序生成用于PET衰减校正的图像的方法
公开(公告)号：US09342903B2
公开(公告)日：2016-05-17
申请号：US14385683
申请日：2013-03-28
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES , SHIMADZU CORPORATION
发明人： Taiga Yamaya , Takayuki Obata , Mikio Suga , Hiroshi Kawaguchi , Yoshiyuki Yamakawa
IPC分类号： G06K9/00 , G06T11/00 , A61B5/055 , A61B5/00 , G01T1/16 , A61B6/03 , G01R33/48 , G06T7/00
CPC分类号： G06T11/005 , A61B5/0035 , A61B5/055 , A61B6/037 , A61B2576/026 , G01R33/481 , G01T1/1603 , G06T7/11 , G06T2207/10088 , G06T2207/10104 , G06T2207/30004
摘要： When an image for PET attenuation correction is generated from an MR image, the MR image captured by MRI is segmented into regions according to pixel values. In a region in which a radiation attenuation coefficient is considered to be uniform, a radiation attenuation correction value is determined by referring to an existing radiation attenuation correction value table. In a region including multiple tissues having different radiation attenuation coefficients, a radiation attenuation correction value is determined by referring to a standard image. In such a manner, an image for PET attenuation correction in which tissues having similar pixel values in the MR image but different attenuation coefficients for radiation can be distinguished and that can accommodate individual differences and an affected area such as a space occupying lesion (for example, a cancer, abscess, or the like) and an organic defect is generated.
摘要翻译：当从MR图像产生用于PET衰减校正的图像时，由MRI捕获的MR图像根据像素值被分割成区域。在辐射衰减系数被认为是均匀的区域中，通过参照现有的辐射衰减校正值表确定辐射衰减校正值。在包括具有不同辐射衰减系数的多个组织的区域中，通过参考标准图像来确定辐射衰减校正值。以这种方式，用于PET衰减校正的图像，其中可以区分在MR图像中具有相似像素值但是具有不同的辐射衰减系数的组织，并且可以适应个体差异和诸如空间占据病变的受影响区域（例如，，癌症，脓肿等），产生有机缺陷。

6. 发明授权

US09176237B2 Coincidence determination method and apparatus of PET device 有权
标题翻译： PET装置的一致性确定方法和装置
公开(公告)号：US09176237B2
公开(公告)日：2015-11-03
申请号：US13846443
申请日：2013-03-18
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES
发明人： Eiji Yoshida , Taiga Yamaya
IPC分类号： G01T1/164 , G01T1/29
CPC分类号： G01T1/164 , G01T1/1647 , G01T1/2985
摘要： In a coincidence determination of a PET device, the PET device uses a scintillator of radioactive isotope containing background noise due to intrinsic radioactivity as a radiation detector. The PET device counts a pair of annihilation radiations that is assumed to occur from a same nuclide. The annihilation radiations are detected within a predetermined coincidence time window by a plurality of radiation detectors. The method includes determining a coincidence with a wide energy window that allows detecting the background noise due to intrinsic radioactivity as multiple coincidences; removing the multiple coincidences; and using an energy window narrower than the wide energy window to limit a coincidence event to a coincidence event in a photopeak from a positron nuclide only.
摘要翻译：在PET装置的重合判定中，PET装置使用由于内在放射性而含有背景噪声的放射性同位素的闪烁体作为放射线检测器。 PET装置计算出假定从同一个核素发生的一对湮灭辐射。通过多个辐射检测器在预定的重合时间窗内检测湮灭辐射。该方法包括确定与宽能量窗口的一致性，其允许将由于固有放射性的背景噪声检测为多重重合; 消除多重巧合; 并且使用比宽能窗口窄的能量窗口，以将符合事件限制在仅来自正电子核素的光峰中的重合事件。

7. 发明授权

US10234570B2 PET device, PET-MRI apparatus, and image processing method 有权
公开(公告)号：US10234570B2
公开(公告)日：2019-03-19
申请号：US13938592
申请日：2013-07-10
申请人： Toshiba Medical Systems Corporation , National Institutes for Quantum and Radiological Science and Technology
发明人： Taiga Yamaya , Takayuki Obata , Iwao Kanno , Takuzo Takayama , Hitoshi Yamagata , Kazuya Okamoto
IPC分类号： G01T1/164 , A61B6/03 , A61B6/00 , G01T1/29 , G01R33/48
摘要： In a PET device, a first detector includes a plurality of first scintillators and detects gamma rays emitted from positron-emitting radionuclides injected into a subject. A second detector is provided on the outer circumferential side of the first detector, includes a plurality of second scintillators arranged in an arrangement surface density lower than that of the first scintillators, and detects gamma rays that have passed through the first detector. A counted information acquiring unit acquires, as first counted information and second counted information, the detection positions, energy values, and detection time regarding gamma rays detected by the first detector and the second detector. Based on the detection time contained in each of the first counted information and the second counted information, an energy value adder generate corrected counted information by summing the energy values contained in the first counted information and the second counted information.

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