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1. 发明授权

US06658082B2 Radiation detector, radiation detecting system and X-ray CT apparatus 有权
公开(公告)号：US06658082B2
公开(公告)日：2003-12-02
申请号：US09928211
申请日：2001-08-13
申请人： Miwa Okumura , Machiko Ono , Toshihiro Rifu , Tomiya Sasaki , Michito Nakayama
发明人： Miwa Okumura , Machiko Ono , Toshihiro Rifu , Tomiya Sasaki , Michito Nakayama
IPC分类号： A61B600
CPC分类号： A61B6/032 , A61B6/027 , A61B6/4488 , G01N23/046 , G01N2223/419 , G01N2223/612 , H01L2224/16225 , H01L2924/15174 , H01L2924/15311
摘要： A radiation detector of this invention includes a scintillator for converting an X-ray incident from a surface side into light, at least one photodiode chip having a plurality of photodiodes for converting the converted light into electrical signals, at least one switching chip having a plurality of switching elements for reading out a plurality of signals from the plurality of photodiodes, and at least one data acquisition chip having a plurality of data acquisition systems for amplifying the plurality of readout signals and converting the signals into digital signals. The photodiode chip, the switching chip, and the data acquisition chip are commonly mounted on a rigid multilayer wiring board.

2. 发明授权

US07003076B2 Radiation detector, radiation detecting system and X-ray CT apparatus 有权
公开(公告)号：US07003076B2
公开(公告)日：2006-02-21
申请号：US10679494
申请日：2003-10-07
申请人： Miwa Okumura , Machiko Ono , Toshihiro Rifu , Tomiya Sasaki , Michito Nakayama
发明人： Miwa Okumura , Machiko Ono , Toshihiro Rifu , Tomiya Sasaki , Michito Nakayama
IPC分类号： H05G1/64
CPC分类号： A61B6/032 , A61B6/027 , A61B6/4488 , G01N23/046 , G01N2223/419 , G01N2223/612 , H01L2224/16225 , H01L2924/15174 , H01L2924/15311
摘要： A radiation detector of this invention includes a scintillator for converting an X-ray incident from a surface side into light, at least one photodiode chip having a plurality of photodiodes for converting the converted light into electrical signals, at least one switching chip having a plurality of switching elements for reading out a plurality of signals from the plurality of photodiodes, and at least one data acquisition chip having a plurality of data acquisition systems for amplifying the plurality of readout signals and converting the signals into digital signals. The photodiode chip, the switching chip, and the data acquisition chip are commonly mounted on a rigid multilayer wiring board.

3. 发明授权

US06947516B2 X-ray CT apparatus 有权
标题翻译： X射线CT装置
公开(公告)号：US06947516B2
公开(公告)日：2005-09-20
申请号：US10077819
申请日：2002-02-20
申请人： Miwa Okumura , Masahiko Yamazaki , Satoru Nakanishi , Toshihiro Rifu , Souji Miyashita
发明人： Miwa Okumura , Masahiko Yamazaki , Satoru Nakanishi , Toshihiro Rifu , Souji Miyashita
IPC分类号： G01T7/00 , A61B6/03 , G01T1/20 , G06T1/00 , A61B6/00
CPC分类号： A61B6/032 , A61B6/027
摘要： An X-ray apparatus including an X-ray source, a rotation mechanism which rotates the X-ray source about a rotational axis, and an X-ray detector having a plurality of detection elements. A blocking member defining a slit structure is provided between the X-ray source and the X-ray detector. The slits of the blocking member include two rows aligned in a channel direction of the detector elements, and two rows staggered in the channel direction, thereby to obtain a CT image with improved spatial resolution. Alternatively, instead of using a blocking member, some of the detection elements of at least one detection segment are staggered in the channel direction with respect to detection elements of another detection segment.
摘要翻译：一种X射线设备，包括X射线源，使X射线源围绕旋转轴线旋转的旋转机构和具有多个检测元件的X射线检测器。限定狭缝结构的阻挡构件设置在X射线源和X射线检测器之间。阻挡构件的狭缝包括在检测器元件的通道方向上排列的两列，并且在通道方向上交错排列的两列，从而获得具有改善的空间分辨率的CT图像。或者，代替使用阻挡构件，至少一个检测段的一些检测元件相对于另一个检测段的检测元件在通道方向上错开。

4. 发明授权

US07853309B2 X-ray CT apparatus and myocardial perfusion image generating system 有权
标题翻译： X射线CT装置和心肌灌注图像生成系统
公开(公告)号：US07853309B2
公开(公告)日：2010-12-14
申请号：US11075667
申请日：2005-03-10
申请人： Takashi Ichihara , Toshihiro Rifu , Joao A. C. Lima , Richard T. George , Albert C. Lardo
发明人： Takashi Ichihara , Toshihiro Rifu , Joao A. C. Lima , Richard T. George , Albert C. Lardo
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B6/481 , A61B6/503 , A61B6/507 , A61B6/541
摘要： An X-ray CT apparatus comprises a blood-flow information acquisition unit, a correction value calculating unit and a blood-flow image generating unit. The blood-flow information acquisition unit obtains information of a relative blood flow rate in the myocardium of the subject based on the CT image. The correction value calculating unit obtains a correction value based on the CT image in a concentration transition period defined to be a period from immediately after start of a continuous injection of a contrast medium into the subject until the contrast medium reaching the myocardium increases and is be in a state where it can be considered that the contrast medium is saturated at a constant value. The blood-flow image generating unit generates a blood flow value image in the myocardium by correcting the information of the relative blood flow rate with the correction value.
摘要翻译： X射线CT装置包括血流信息获取单元，校正值计算单元和血流图像生成单元。血流信息获取单元基于CT图像获取被检体的心肌的相对血流量的信息。校正值计算单元获得校正值，该校正值基于浓缩过渡时段中的CT图像，所述浓度过渡期定义为从造影剂连续注射到对象之后的开始之后的周期，直到达到心肌的造影剂增加，并且为在可以认为造影剂以恒定值饱和的状态下。血流图像生成单元通过利用校正值校正相对血流量的信息来生成心肌中的血流值图像。

5. 发明授权

US07330594B2 Image enhancement or correction software, method, apparatus and system for substantially minimizing blur in the scanned image 有权
标题翻译：用于基本上最小化扫描图像中的模糊的图像增强或校正软件，方法，装置和系统
公开(公告)号：US07330594B2
公开(公告)日：2008-02-12
申请号：US10903619
申请日：2004-07-30
申请人： Toshihiro Rifu
发明人： Toshihiro Rifu
IPC分类号： G06K9/62 , G06K9/00
CPC分类号： G06T5/003 , G06T5/50 , G06T2200/04 , G06T2207/10081 , G06T2207/30101
摘要： Three-dimensionally reconstructed images are not ideal due to blur or smear that is caused by various sources in an X-ray CT scanner. In order to substantially minimize the blur in the three-dimensionally reconstructed image, a known PSF is weighed according to a combination of predetermined parameters. The parameters include two types of information. One group of the parameters is related to device characteristics of the scanner device while the other is related to the scanning conditions of a particular scan. The improvement is performed in any combination of the X, Y and Z directions. The improved PSF's are used to de-convolute the three-dimensionally reconstructed CT image. As a result, the blur and smear are substantially removed from the three-dimensionally reconstructed image data for good visualization as well as accurate physical measurements in the scanned image. The improved techniques according to the current invention are applicable to two-dimensional image data.
摘要翻译：由于X射线CT扫描仪中的各种来源引起的模糊或拖尾，三维重建图像不理想。为了基本上最小化三维重建图像中的模糊，根据预定参数的组合来称量已知的PSF。参数包括两种类型的信息。一组参数与扫描仪设备的设备特性有关，而另一组与特定扫描的扫描条件有关。在X，Y和Z方向的任意组合中进行改进。改进的PSF用于对三维重建的CT图像进行去卷积。结果，模糊和拖尾被显着地从三维重建的图像数据中去除，以便良好的可视化以及扫描图像中的准确的物理测量。根据本发明的改进技术可应用于二维图像数据。

6. 发明授权

US10186056B2 System and method for estimating vascular flow using CT imaging 有权
公开(公告)号：US10186056B2
公开(公告)日：2019-01-22
申请号：US13425724
申请日：2012-03-21
申请人： Robert F. Senzig , Ravikanth Avancha , Bijan Dorri , Sandeep Dutta , Steven J. Gray , Jiang Hsieh , John Irvin Jackson , Giridhar Jothiprasad , Paul Edgar Licato , Darin Robert Okerlund , Toshihiro Rifu , Saad Ahmed Sirohey , Basel Taha , Peter Michael Edic , Jerome Knoplioch , Rahul Bhotika
发明人： Robert F. Senzig , Ravikanth Avancha , Bijan Dorri , Sandeep Dutta , Steven J. Gray , Jiang Hsieh , John Irvin Jackson , Giridhar Jothiprasad , Paul Edgar Licato , Darin Robert Okerlund , Toshihiro Rifu , Saad Ahmed Sirohey , Basel Taha , Peter Michael Edic , Jerome Knoplioch , Rahul Bhotika
IPC分类号： A61B5/05 , G06T11/00 , A61B6/03 , A61B6/00 , G06T7/00
摘要： A system and method for estimating vascular flow using CT imaging include a computer readable storage medium having stored thereon a computer program comprising instructions, which, when executed by a computer, cause the computer to acquire a first set of data comprising anatomical information of an imaging subject, the anatomical information comprises information of at least one vessel. The instructions further cause the computer to process the anatomical information to generate an image volume comprising the at least one vessel, generate hemodynamic information based on the image volume, and acquire a second set of data of the imaging subject. The computer is also caused to generate an image comprising the hemodynamic information in combination with a visualization based on the second set of data.

7. 发明申请

US20120155617A1 PHANTOM FOR SPECTRAL CT IMAGE SYSTEM CALIBRATION 有权
标题翻译：用于光谱CT图像系统校准的PHANTOM
公开(公告)号：US20120155617A1
公开(公告)日：2012-06-21
申请号：US12968393
申请日：2010-12-15
申请人： Sandeep Dutta , Naveen Chandra , Toshihiro Rifu
发明人： Sandeep Dutta , Naveen Chandra , Toshihiro Rifu
IPC分类号： G01D18/00
CPC分类号： A61B6/583 , A61B6/032 , A61B6/06 , A61B6/4266 , A61B6/482
摘要： A phantom includes a housing enclosing an interior volume and having a plurality of passages formed therein, wherein each passage is fluidly isolated from the interior volume. First and second inserts are included and configured to be positioned in a first passage of the plurality of passages and include materials having a known material density. The material is selected from iodine, hydroxyapatite (HAP), tricalcium phosphate (TCP), body fat, fatty plaque, sodium chloride (NaCl), gold (Au), and iron (Fe). The material of the inserts can be different materials or the same material at different densities.
摘要翻译：体模包括封闭内部容积并具有形成在其中的多个通道的壳体，其中每个通道与内部容积流体隔离。第一和第二插入件被包括并构造成定位在多个通道的第一通道中并且包括具有已知材料密度的材料。该材料选自碘，羟基磷灰石（HAP），磷酸三钙（TCP），体脂肪，脂肪斑块，氯化钠（NaCl），金（Au）和铁（Fe）。插入物的材料可以是不同的材料或不同密度的相同材料。

8. 发明申请

US20050220357A1 Image enhancement or correction software, method, apparatus and system for substantially minimizing blur in the scanned image 有权
标题翻译：用于基本上最小化扫描图像中的模糊的图像增强或校正软件，方法，装置和系统
公开(公告)号：US20050220357A1
公开(公告)日：2005-10-06
申请号：US10903619
申请日：2004-07-30
申请人： Toshihiro Rifu
发明人： Toshihiro Rifu
IPC分类号： A61B5/055 , A61B6/03 , A61B8/14 , G06K9/40 , G06T1/00 , G06T5/00 , G06T5/50
CPC分类号： G06T5/003 , G06T5/50 , G06T2200/04 , G06T2207/10081 , G06T2207/30101
摘要： Three-dimensionally reconstructed images are not ideal due to blur or smear that is caused by various sources in an X-ray CT scanner. In order to substantially minimize the blur in the three-dimensionally reconstructed image, a known PSF is weighed according to a combination of predetermined parameters. The parameters include two types of information. One group of the parameters is related to device characteristics of the scanner device while the other is related to the scanning conditions of a particular scan. The improvement is performed in any combination of the X, Y and Z directions. The improved PSF's are used to de-convolute the three-dimensionally reconstructed CT image. As a result, the blur and smear are substantially removed from the three-dimensionally reconstructed image data for good visualization as well as accurate physical measurements in the scanned image. The improved techniques according to the current invention are applicable to two-dimensional image data.
摘要翻译：由于X射线CT扫描仪中的各种来源引起的模糊或拖尾，三维重建图像不理想。为了基本上最小化三维重建图像中的模糊，根据预定参数的组合来称量已知的PSF。参数包括两种类型的信息。一组参数与扫描仪设备的设备特性有关，而另一组与特定扫描的扫描条件有关。在X，Y和Z方向的任意组合中进行改进。改进的PSF用于对三维重建的CT图像进行去卷积。结果，模糊和拖尾被显着地从三维重建的图像数据中去除，以便良好的可视化以及扫描图像中的准确的物理测量。根据本发明的改进技术可应用于二维图像数据。

9. 发明授权

US06215844B1 X-ray computed tomography apparatus 有权
标题翻译： X射线计算机断层摄影装置
公开(公告)号：US06215844B1
公开(公告)日：2001-04-10
申请号：US09366753
申请日：1999-08-04
申请人： Akira Adachi , Toshihiro Rifu
发明人： Akira Adachi , Toshihiro Rifu
IPC分类号： A61B600
CPC分类号： A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/583
摘要： In an X-ray computed tomography apparatus, an X-ray tube for generating an X-ray is opposed to a main X-ray detector in order to acquire a projection data set necessary to reconstruct a tomogram. A first sub X-ray detector is arranged at the righthand of the main X-ray detector. A second sub X-ray detector is arranged at the lefthand of the main X-ray detector. Arranging the sub X-ray detectors adjacent to the respective opposite sides of the main X-ray detector enables accurate detection of the shift of an X-ray radiation field, and hence enables the reduction of errors due to the shift.
摘要翻译：在X射线计算机断层摄影装置中，用于产生X射线的X射线管与主X射线检测器相对，以获得重建断层图像所需的投影数据集。第一副X射线检测器设置在主X射线检测器的右侧。第二副X射线检测器设置在主X射线检测器的左侧。将副X射线检测器配置在与主X射线检测器的相对侧相邻的位置，能够精确地检测X射线照射场的偏移，因此能够减少由于偏移引起的误差。

10. 发明授权

US08494244B2 System and method for blood vessel stenosis visualization and quantification using spectral CT analysis 有权
标题翻译：使用光谱CT分析进行血管狭窄可视化和定量的系统和方法
公开(公告)号：US08494244B2
公开(公告)日：2013-07-23
申请号：US12890835
申请日：2010-09-27
申请人： Sandeep Dutta , Darin Robert Okerlund , Toshihiro Rifu
发明人： Sandeep Dutta , Darin Robert Okerlund , Toshihiro Rifu
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B6/482 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B6/583
摘要： A system and method for dual energy CT spectral imaging that provides for accurate blood vessel stenosis visualization and quantification is disclosed. The CT system includes an x-ray source configured to project x-rays toward a region-of-interest of a patient that includes a blood vessel in a stenosed condition and having a plaque material therein. The CT system also includes an x-ray detector to receive x-rays emitted by the x-ray source and attenuated by the region-of-interest, a data acquisition system (DAS) operably connected to the x-ray detector, and a computer programmed to obtain a first set of CT image data for the region-of-interest at a first chromatic energy level, obtain a second set of CT image data for the region-of-interest at a second chromatic energy level that is higher than the first chromatic energy level, and identify plaque material in the region-of-interest by analyzing the second set of CT image data.
摘要翻译：公开了一种用于双能量CT光谱成像的系统和方法，其提供精确的血管狭窄可视化和定量。 CT系统包括x射线源，其构造成将x射线投射到患者的感兴趣区域，该患者包括处于狭窄状态的血管并且其中具有斑块材料。 CT系统还包括一个x射线检测器，用于接收由X射线源发射并被感兴趣区域衰减的X射线，可操作地连接到x射线检测器的数据采集系统（DAS），以及计算机被编程为在第一色能级获得用于感兴趣区域的第一组CT图像数据，在高于第二色能级的第二色能级获得感兴趣区域的第二组CT图像数据通过分析第二组CT图像数据，识别感兴趣区域中的斑块物质。

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