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1. 发明授权

US07853309B2 X-ray CT apparatus and myocardial perfusion image generating system 有权
标题翻译： X射线CT装置和心肌灌注图像生成系统
公开(公告)号：US07853309B2
公开(公告)日：2010-12-14
申请号：US11075667
申请日：2005-03-10
申请人： Takashi Ichihara , Toshihiro Rifu , Joao A. C. Lima , Richard T. George , Albert C. Lardo
发明人： Takashi Ichihara , Toshihiro Rifu , Joao A. C. Lima , Richard T. George , Albert C. Lardo
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B6/481 , A61B6/503 , A61B6/507 , A61B6/541
摘要： An X-ray CT apparatus comprises a blood-flow information acquisition unit, a correction value calculating unit and a blood-flow image generating unit. The blood-flow information acquisition unit obtains information of a relative blood flow rate in the myocardium of the subject based on the CT image. The correction value calculating unit obtains a correction value based on the CT image in a concentration transition period defined to be a period from immediately after start of a continuous injection of a contrast medium into the subject until the contrast medium reaching the myocardium increases and is be in a state where it can be considered that the contrast medium is saturated at a constant value. The blood-flow image generating unit generates a blood flow value image in the myocardium by correcting the information of the relative blood flow rate with the correction value.
摘要翻译： X射线CT装置包括血流信息获取单元，校正值计算单元和血流图像生成单元。血流信息获取单元基于CT图像获取被检体的心肌的相对血流量的信息。校正值计算单元获得校正值，该校正值基于浓缩过渡时段中的CT图像，所述浓度过渡期定义为从造影剂连续注射到对象之后的开始之后的周期，直到达到心肌的造影剂增加，并且为在可以认为造影剂以恒定值饱和的状态下。血流图像生成单元通过利用校正值校正相对血流量的信息来生成心肌中的血流值图像。

2. 发明授权

US08160338B2 X-ray CT apparatus and myocardial perfusion image generating system 有权
标题翻译： X射线CT装置和心肌灌注图像生成系统
公开(公告)号：US08160338B2
公开(公告)日：2012-04-17
申请号：US12123776
申请日：2008-05-20
申请人： Takashi Ichihara , Richard T. George , Joao A. C. Lima , Albert C. Lardo
发明人： Takashi Ichihara , Richard T. George , Joao A. C. Lima , Albert C. Lardo
IPC分类号： G06K9/00
CPC分类号： A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , A61B6/541
摘要： An apparatus includes a transformation table acquiring unit, a blood-flow information acquisition unit and a blood-flow image generating unit. The transformation table acquiring unit obtains a transformation table for transforming unspecified information representing a concentration of a contrast medium in a myocardium into an unspecified blood flow value image based on a CT image acquired in a concentration transition period. The blood-flow information acquisition unit obtains information representing the concentration of the contrast medium based on a CT image acquired during a constant concentration period. The blood-flow image generating unit generates a blood flow value image based on the information representing the concentration of the contrast medium according to the transformation table.
摘要翻译：一种装置包括变换表获取单元，血流信息获取单元和血流图像生成单元。变换表获取单元基于在浓度过渡期获取的CT图像，获得用于将表示心肌中的造影剂的浓度的未指定信息变换为未指定的血流值图像的变换表。血流信息获取单元基于在恒定浓度期间获取的CT图像，获得表示造影剂浓度的信息。血流图像生成单元根据变换表，根据表示造影剂的浓度的信息生成血流量图像。

3. 发明授权

US08615116B2 Combined multi-detector CT angiography and CT myocardial perfusion imaging for the diagnosis of coronary artery disease 有权
标题翻译：联合多检测CT血管造影和CT心肌灌注显像诊断冠状动脉疾病
公开(公告)号：US08615116B2
公开(公告)日：2013-12-24
申请号：US12680152
申请日：2008-09-29
申请人： Albert Clark Lardo , Richard T. George , Joao A. C. Lima , Eduardo T. Marban , Takashi Ichihara
发明人： Albert Clark Lardo , Richard T. George , Joao A. C. Lima , Eduardo T. Marban , Takashi Ichihara
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： A61B6/504 , A61B5/7285 , A61B6/032 , A61B6/463 , A61B6/466 , A61B6/507 , A61B6/508 , A61B6/541
摘要： A computed tomography system has a support stage constructed and arranged to support a subject while under observation, an x-ray illumination system arranged proximate the support stage to illuminate the subject with x-rays, an x-ray detection system arranged proximate the support stage to detect x-rays after they pass through the subject and to provide signals based on the detected x-rays, and a data processing system in communication with the x-ray detection system to receive the signals from the x-ray detection system. The computed tomography system has a dynamic mode of operation and a scanning mode of operation. The data processing system extracts information concerning a dynamic process of the subject based on signals from both the dynamic mode and the scanning mode of operation.
摘要翻译：计算机断层摄影系统具有构造和布置成在观察期间支撑被摄体的支撑台，布置在支撑台附近以用X射线照射受试者的X射线照射系统，布置在支撑台附近的X射线检测系统以检测X射线穿过被摄体之后并且基于检测到的x射线提供信号，以及与x射线检测系统通信以接收来自X射线检测系统的信号的数据处理系统。计算机断层摄影系统具有动态操作模式和扫描操作模式。数据处理系统基于来自动态模式和扫描操作模式的信号提取关于对象的动态处理的信息。

4. 发明授权

US09072490B2 Image processing apparatus and image processing method 有权
标题翻译：图像处理装置和图像处理方法
公开(公告)号：US09072490B2
公开(公告)日：2015-07-07
申请号：US12973115
申请日：2010-12-20
申请人： Takuya Sakaguchi , Hisato Takemoto , Joao A. C. Lima , Richard T. George , Jeff Trost
发明人： Takuya Sakaguchi , Hisato Takemoto , Joao A. C. Lima , Richard T. George , Jeff Trost
IPC分类号： G06K9/00 , A61B6/00 , A61B5/055 , G06T5/50
CPC分类号： A61B6/463 , A61B5/055 , A61B6/503 , A61B6/504 , A61B6/507 , G06T5/50 , G06T2207/10116 , G06T2207/20224 , G06T2207/30048 , G06T2207/30101
摘要： In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.
摘要翻译：在一个实施例中，图像处理装置包括差分图像生成单元和显示控制单元。差分图像生成单元通过从第一X射线透射图像计算第二X射线透射图像的差异来生成差分图像，第二X射线透射图像是检查对象的心肌组织为不透明，第一X射线透射图像是将被检查对象的心肌组织用注射到冠状动脉中的造影剂不透明的图像。显示控制单元进行控制，使得预定的显示单元显示由差分图像生成单元生成的差分图像。

5. 发明申请

US20120155737A1 IMAGE PROCESSING APPARATUS AND IMAGE PROCESSING METHOD 有权
标题翻译：图像处理装置和图像处理方法
公开(公告)号：US20120155737A1
公开(公告)日：2012-06-21
申请号：US12973115
申请日：2010-12-20
申请人： Takuya SAKAGUCHI , Hisato Takemoto , Joao A. C. Lima , Richard T. George , Jeff Trost
发明人： Takuya SAKAGUCHI , Hisato Takemoto , Joao A. C. Lima , Richard T. George , Jeff Trost
IPC分类号： G06K9/00 , G06T11/20 , G09G5/00
CPC分类号： A61B6/463 , A61B5/055 , A61B6/503 , A61B6/504 , A61B6/507 , G06T5/50 , G06T2207/10116 , G06T2207/20224 , G06T2207/30048 , G06T2207/30101
摘要： In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.
摘要翻译：在一个实施例中，图像处理装置包括差分图像生成单元和显示控制单元。差分图像生成单元通过从第一X射线透射图像计算第二X射线透射图像的差异来生成差分图像，第二X射线透射图像是检查对象的心肌组织为不透明，第一X射线透射图像是将被检查对象的心肌组织用注射到冠状动脉中的造影剂不透明的图像。显示控制单元进行控制，使得预定的显示单元显示由差分图像生成单元生成的差分图像。

6. 发明授权

US08498462B2 Image processing apparatus and program 有权
标题翻译：图像处理装置和程序
公开(公告)号：US08498462B2
公开(公告)日：2013-07-30
申请号：US12236934
申请日：2008-09-24
申请人： Hiroyuki Niinuma , Kakuya Kitagawa , Joao A. C. Lima , Yasuko Fujisawa , Miwa Okumura
发明人： Hiroyuki Niinuma , Kakuya Kitagawa , Joao A. C. Lima , Yasuko Fujisawa , Miwa Okumura
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T2207/10072 , G06T2207/30048 , G06T2207/30101
摘要： An image processing apparatus includes a storage unit which stores volume data associated with an area including a contrast-enhanced artery as an examination target, a first calculation unit which calculates a plurality of partial atherosclerotic indexes associated with a plurality of portions of the artery on the basis of morphological information associated with the artery which is obtained from the volume data, a second calculation unit which calculates a whole atherosclerotic index associated with the entire artery including the plurality of portions on the basis of the morphological information associated with the artery, and a display unit which displays evaluation information based on the calculated whole atherosclerotic index.
摘要翻译：图像处理装置包括存储单元，其存储与包括对比度增强动脉的区域相关联的体积数据作为检查对象;第一计算单元，计算与所述动脉的多个部分相关联的多个部分动脉粥样硬化指数基于与体积数据获得的与动脉相关联的形态学信息，第二计算单元，其基于与动脉相关联的形态信息计算与包括多个部分的整个动脉相关联的整个动脉粥样硬化指数，以及显示单元，其基于计算的整个动脉粥样硬化指数显示评估信息。

7. 发明申请

US20100111380A1 MEDICAL IMAGE ANALYSIS APPARATUS AND IMAGE ANALYSIS CONTROL PROGRAM 有权
标题翻译：医学图像分析装置和图像分析控制程序
公开(公告)号：US20100111380A1
公开(公告)日：2010-05-06
申请号：US12265302
申请日：2008-11-05
申请人： Tetsuya Kawagishi , Hiroyuki Ohuchi , Yasuhiko Abe , Thomas Helle-Valle , Joao A. C. Lima
发明人： Tetsuya Kawagishi , Hiroyuki Ohuchi , Yasuhiko Abe , Thomas Helle-Valle , Joao A. C. Lima
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/248 , G06T2207/30048
摘要： A motion function of a biological tissue is efficiently evaluated on the basis of image data collected from different medical image diagnostic apparatuses. In terms of a common analysis algorithm applied to subject's time-series image data supplied from a separate medical image diagnostic apparatus, a setting part sets a plurality of interest points on a myocardial tissue of a reference image data extracted from the image data, and a tracking process part measures a motion parameter on the basis of displacement information of the myocardial tissue at the interest points obtained by a tracking process between the reference image data and subsequent image data thereof. Meanwhile, a data creating unit creates parameter image data showing two-dimension distribution of the motion parameter or parameter time-series data showing a variation in time of the motion parameter as parameter data on the basis of the measurement result, and displays the parameter data.
摘要翻译：基于从不同的医学图像诊断装置收集的图像数据，有效地评价生物体的运动功能。从应用于从单独的医用图像诊断装置提供的被检者的时间序列图像数据的共同分析算法，设定部设定从图像数据提取的参照图像数据的心肌组织上的多个兴趣点，跟踪处理部分基于通过参考图像数据和其后续图像数据之间的跟踪处理获得的感兴趣点处的心肌组织的位移信息来测量运动参数。同时，数据创建单元基于测量结果创建表示运动参数的时间序列变化的运动参数或参数时间序列数据的二维分布的参数图像数据作为参数数据，并且显示参数数据。

8. 发明授权

US08208703B2 Medical image analysis apparatus and image analysis control program 有权
标题翻译：医学图像分析仪器和图像分析控制程序
公开(公告)号：US08208703B2
公开(公告)日：2012-06-26
申请号：US12265302
申请日：2008-11-05
申请人： Tetsuya Kawagishi , Hiroyuki Ohuchi , Yasuhiko Abe , Thomas Helle-Valle , Joao A. C. Lima
发明人： Tetsuya Kawagishi , Hiroyuki Ohuchi , Yasuhiko Abe , Thomas Helle-Valle , Joao A. C. Lima
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/248 , G06T2207/30048
摘要： A motion function of a biological tissue is efficiently evaluated on the basis of image data collected from different medical image diagnostic apparatuses. In terms of a common analysis algorithm applied to subject's time-series image data supplied from a separate medical image diagnostic apparatus, a setting part sets a plurality of interest points on a myocardial tissue of a reference image data extracted from the image data, and a tracking process part measures a motion parameter on the basis of displacement information of the myocardial tissue at the interest points obtained by a tracking process between the reference image data and subsequent image data thereof. Meanwhile, a data creating unit creates parameter image data showing two-dimension distribution of the motion parameter or parameter time-series data showing a variation in time of the motion parameter as parameter data on the basis of the measurement result, and displays the parameter data.
摘要翻译：基于从不同的医学图像诊断装置收集的图像数据，有效地评价生物体的运动功能。从应用于从单独的医用图像诊断装置提供的被检者的时间序列图像数据的共同分析算法，设定部设定从图像数据提取的参照图像数据的心肌组织上的多个兴趣点，跟踪处理部分基于通过参考图像数据和其后续图像数据之间的跟踪处理获得的感兴趣点处的心肌组织的位移信息来测量运动参数。同时，数据创建单元基于测量结果创建表示运动参数的时间序列变化的运动参数或参数时间序列数据的二维分布的参数图像数据作为参数数据，并且显示参数数据。

9. 发明授权

US06408202B1 Transesophageal magnetic resonance analysis method and apparatus 有权
标题翻译：经食管磁共振分析方法及装置
公开(公告)号：US06408202B1
公开(公告)日：2002-06-18
申请号：US09432960
申请日：1999-11-03
申请人： Joao A. C. Lima , Kendrick A. Shunk , Ergin Atalar
发明人： Joao A. C. Lima , Kendrick A. Shunk , Ergin Atalar
IPC分类号： A61B505
CPC分类号： G01R33/34084 , G01R33/34 , G01R33/34053 , G01R33/3657
摘要： A method of transesophageal magnetic resonance analysis of a patient, such as an animal or human, includes providing a loopless antenna formed from a flexible coaxial cable having an extended center conductor at the distal end thereof. A distal portion of the loopless antenna is secured within a Levin-type gastric tube. The gastric tube which receives the loopless antenna is inserted in the esophagus of the patient. A tuning, matching and decoupling circuit for the loopless antenna is employed external to the patient. The tuning, matching and decoupling circuit is electrically connected to a magnetic resonance imaging scanner. The magnetic resonance imaging scanner is employed to display an image of the aorta of the patient.
摘要翻译：患者（例如动物或人）的经食管磁共振分析的方法包括提供由其远端具有延伸的中心导体的柔性同轴电缆形成的无孔天线。无孔天线的远端部分固定在Levin型胃管内。接收无腰天线的胃管插入患者的食道。用于无孔天线的调谐，匹配和去耦电路在患者外部使用。调谐，匹配和去耦电路电连接到磁共振成像扫描仪。使用磁共振成像扫描器来显示患者的主动脉的图像。

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