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    • 9. 发明授权
    • Cardiac sense amplifier for capture verification
    • 心脏放大器用于捕获验证
    • US06427085B1
    • 2002-07-30
    • US09309951
    • 1999-05-11
    • Scot C. BoonMark GryzwaMichael LydenQingsheng ZhuPaul Haefner
    • Scot C. BoonMark GryzwaMichael LydenQingsheng ZhuPaul Haefner
    • A61N137
    • A61N1/3712
    • A cardiac rhythm management device having a capture verification sensing circuit for use in either a normal beat to beat pacing mode or an autothreshold mode. The cardiac rhythm management device is coupled to one or more pacing leads having pacing/sensing electrodes coupled thereto, and includes a sensing circuit for sensing electrical activity of the patient's heart, wherein the sensing circuit includes a dedicated evoked response sense amplifier and at least one high pass coupling capacitor electrically connected as a portion of a high pass network and between a pacing/sensing electrode and a blanking switch. A plurality of high pass coupling capacitors are coupled in parallel each having a separate blanking switch, thereby creating a differential network to offset imbalance sensed from the electrode due to extraneous factors.
    • 一种具有捕获验证感测电路的心律管理装置,其用于正常搏动以节拍起搏模式或自阈值模式。 心律管理装置耦合到具有与之相连的起搏/感测电极的一个或多个起搏引线,并且包括用于感测患者心脏的电活动的感测电路,其中感测电路包括专用的诱发响应读出放大器和至少一个 高通耦合电容器作为高通网络的一部分并且在起搏/感测电极和消隐开关之间电连接。 多个高通耦合电容器并联耦合,每个具有单独的消隐开关,由此产生差分网络以抵消由于外部因素而从电极感测的不平衡。
    • 10. 发明授权
    • Rate management during automatic capture verification
    • 自动捕获验证期间的费率管理
    • US06473649B1
    • 2002-10-29
    • US09470269
    • 1999-12-22
    • Mark GryzwaQingsheng Zhu
    • Mark GryzwaQingsheng Zhu
    • A61N137
    • A61N1/3712Y10S128/901
    • An implantable cardiac rhythm management device capable of automatically detecting intrinsic and evoked response of a patient's heart and suitable for use during capture verification. The device of the present invention may operate in an automatic capture verification mode, wherein an electrocardiogram signal of a patient's heart is received and used by the device to determine whether a stimulation pulse evokes a response by the patient's heart. The device suspends the automatic capture verification mode and/or adjust the detection threshold dependent upon detected and/or measured noise, a determined amplitude of evoked response, a determined modulation in the evoked response, or detected and/or measured artifact. Further, the sensing circuit of the rhythm management device of the present invention reduces afterpotentials that result due to delivery of the stimulation pulses.
    • 一种植入式心律管理装置,其能够自动检测患者心脏的内在和诱发反应并适于在捕获验证期间使用。 本发明的装置可以在自动捕获验证模式下操作,其中由装置接收并使用患者心脏的心电图信号,以确定刺激脉冲是否引起患者心脏的反应。 取决于检测到的和/或测量的噪声,所确定的诱发响应幅度,诱发响应中的确定调制,或检测到的和/或测量的伪影,该装置暂停自动捕获验证模式和/或调整检测阈值。 此外,本发明的节律管理装置的感测电路减少了由于刺激脉冲的传送而导致的后电位。