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1. 发明授权

US08373556B2 Medical data transport over wireless life critical network 有权
公开(公告)号：US08373556B2
公开(公告)日：2013-02-12
申请号：US13181176
申请日：2011-07-12
申请人： John R. LaLonde , William Mass , Kenneth P. Hoyme , David C. Johnson , Joe Bange , Mark Gryzwa
发明人： John R. LaLonde , William Mass , Kenneth P. Hoyme , David C. Johnson , Joe Bange , Mark Gryzwa
IPC分类号： G08B1/08
CPC分类号： G08B21/02 , A61B5/0026 , A61B5/0452 , A61B5/747 , A61N1/37211 , A61N1/37282 , G06F19/00 , G06F19/3418 , G06Q50/24 , G08C17/02 , G16H40/20 , G16H40/40 , H04L67/12 , H04W12/04 , H04W12/06
摘要： A portable patient communicator (PPC) includes a portable housing that supports a processor coupled to memory for storing medical firmware and wireless radio firmware, first and second radios, a processor, and a power source. Communications between a patient implantable medical device (PIMD) and the first radio of the PPC are effected in accordance with program instructions of the medical firmware, and communications between the second radio of the PPC and the wireless network are effected in accordance with program instructions of the wireless radio firmware. Data from the PIMD is received via the first radio to which a priority level is assigned, such as in a tiered manner. A data transport mechanism is selected among disparate data transport mechanisms based at least in part on the priority level. PIMD data is transmitted to the wireless network using the selected transport mechanism via the second radio.

2. 发明授权

US07060030B2 Two-hop telemetry interface for medical device 有权
公开(公告)号：US07060030B2
公开(公告)日：2006-06-13
申请号：US10041725
申请日：2002-01-08
申请人： Jeffrey A. Von Arx , Michael J. Lyden , William J. Linder , Scott T. Mazar , Allan T. Koshiol , Mark Gryzwa , Dorothy Nauman , Scott Hostine
发明人： Jeffrey A. Von Arx , Michael J. Lyden , William J. Linder , Scott T. Mazar , Allan T. Koshiol , Mark Gryzwa , Dorothy Nauman , Scott Hostine
IPC分类号： A61B5/00
CPC分类号： A61N1/08 , G08C2201/40
摘要： This document discusses a system that includes an intermediary telemetry interface device for communicating between a cardiac rhythm management system or other implantable medical device and a programmer or other remote device. One example provides an inductive near-field communication link between the telemetry interface and the implantable medical device, and a radio-frequency (RF) far-field communication link between the telemetry interface device and the remote device. The telemetry interface device provides data buffering. In another example, the telemetry interface device includes a data processing module for compressing and/or decompressing data, or for extracting information from data. Such information extraction may include obtaining heart rate, interval, and/or depolarization morphology information from an electrogram signal received from the implantable medical device.

3. 发明授权

US06427085B1 Cardiac sense amplifier for capture verification 有权
标题翻译：心脏放大器用于捕获验证
公开(公告)号：US06427085B1
公开(公告)日：2002-07-30
申请号：US09309951
申请日：1999-05-11
申请人： Scot C. Boon , Mark Gryzwa , Michael Lyden , Qingsheng Zhu , Paul Haefner
发明人： Scot C. Boon , Mark Gryzwa , Michael Lyden , Qingsheng Zhu , Paul Haefner
IPC分类号： A61N137
CPC分类号： A61N1/3712
摘要： A cardiac rhythm management device having a capture verification sensing circuit for use in either a normal beat to beat pacing mode or an autothreshold mode. The cardiac rhythm management device is coupled to one or more pacing leads having pacing/sensing electrodes coupled thereto, and includes a sensing circuit for sensing electrical activity of the patient's heart, wherein the sensing circuit includes a dedicated evoked response sense amplifier and at least one high pass coupling capacitor electrically connected as a portion of a high pass network and between a pacing/sensing electrode and a blanking switch. A plurality of high pass coupling capacitors are coupled in parallel each having a separate blanking switch, thereby creating a differential network to offset imbalance sensed from the electrode due to extraneous factors.
摘要翻译：一种具有捕获验证感测电路的心律管理装置，其用于正常搏动以节拍起搏模式或自阈值模式。心律管理装置耦合到具有与之相连的起搏/感测电极的一个或多个起搏引线，并且包括用于感测患者心脏的电活动的感测电路，其中感测电路包括专用的诱发响应读出放大器和至少一个高通耦合电容器作为高通网络的一部分并且在起搏/感测电极和消隐开关之间电连接。多个高通耦合电容器并联耦合，每个具有单独的消隐开关，由此产生差分网络以抵消由于外部因素而从电极感测的不平衡。

4. 发明授权

US07978062B2 Medical data transport over wireless life critical network 有权
标题翻译：医疗数据传输通过无线生命关键网络
公开(公告)号：US07978062B2
公开(公告)日：2011-07-12
申请号：US12151869
申请日：2008-05-09
申请人： John LaLonde , William Mass , Kenneth Hoyme , David C. Johnson , Joe Bange , Mark Gryzwa
发明人： John LaLonde , William Mass , Kenneth Hoyme , David C. Johnson , Joe Bange , Mark Gryzwa
IPC分类号： G08B1/08
CPC分类号： G08B21/02 , A61B5/0026 , A61B5/0452 , A61B5/747 , A61N1/37211 , A61N1/37282 , G06F19/00 , G06F19/3418 , G06Q50/24 , G08C17/02 , G16H40/20 , G16H40/40 , H04L67/12 , H04W12/04 , H04W12/06
摘要： A portable patient communicator (PPC) includes a portable housing that supports a processor coupled to memory for storing medical firmware and wireless radio firmware, first and second radios, a processor, and a power source. Communications between a patient implantable medical device (PIMD) and the first radio of the PPC are effected in accordance with program instructions of the medical firmware, and communications between the second radio of the PPC and the wireless network are effected in accordance with program instructions of the wireless radio firmware. Data from the PIMD is received via the first radio to which a priority level is assigned, such as in a tiered manner. A data transport mechanism is selected among disparate data transport mechanisms based at least in part on the priority level. PIMD data is transmitted to the wireless network using the selected transport mechanism via the second radio.
摘要翻译：便携式病人通信器（PPC）包括便携式外壳，其支持耦合到存储器的处理器，用于存储医疗固件和无线无线电固件，第一和第二无线电设备，处理器和电源。病人可植入医疗设备（PIMD）和PPC的第一无线电之间的通信根据医疗固件的程序指令进行，PPC的第二无线电与无线网络之间的通信根据程序指令无线无线固件。来自PIMD的数据经由分配有优先级的第一无线电接收，例如以分层方式。至少部分地基于优先级，在不同的数据传输机制中选择数据传输机制。使用所选择的传送机制经由第二无线电将PIMD数据发送到无线网络。

5. 发明申请

US20090058635A1 Medical data transport over wireless life critical network 有权
标题翻译：医疗数据传输通过无线生命关键网络
公开(公告)号：US20090058635A1
公开(公告)日：2009-03-05
申请号：US12151869
申请日：2008-05-09
申请人： John LaLonde , William Mass , Kenneth Hoyme , David C. Johnson , Joe Bange , Mark Gryzwa
发明人： John LaLonde , William Mass , Kenneth Hoyme , David C. Johnson , Joe Bange , Mark Gryzwa
IPC分类号： G08B1/08 , G06Q50/00
CPC分类号： G08B21/02 , A61B5/0026 , A61B5/0452 , A61B5/747 , A61N1/37211 , A61N1/37282 , G06F19/00 , G06F19/3418 , G06Q50/24 , G08C17/02 , G16H40/20 , G16H40/40 , H04L67/12 , H04W12/04 , H04W12/06
摘要： A portable patient communicator (PPC) includes a portable housing that supports a processor coupled to memory for storing medical firmware and wireless radio firmware, first and second radios, a processor, and a power source. Communications between a patient implantable medical device (PIMD) and the first radio of the PPC are effected in accordance with program instructions of the medical firmware, and communications between the second radio of the PPC and the wireless network are effected in accordance with program instructions of the wireless radio firmware. Data from the PIMD is received via the first radio to which a priority level is assigned, such as in a tiered manner. A data transport mechanism is selected among disparate data transport mechanisms based at least in part on the priority level. PIMD data is transmitted to the wireless network using the selected transport mechanism via the second radio.
摘要翻译：便携式病人通信器（PPC）包括便携式外壳，其支持耦合到存储器的处理器，用于存储医疗固件和无线无线电固件，第一和第二无线电设备，处理器和电源。患者可植入医疗设备（PIMD）和PPC的第一无线电之间的通信是根据医疗固件的程序指令进行的，并且PPC的第二无线电与无线网络之间的通信根据程序指令无线无线固件。来自PIMD的数据经由分配有优先级的第一无线电接收，例如以分层方式。至少部分地基于优先级，在不同的数据传输机制中选择数据传输机制。使用所选择的传送机制经由第二无线电将PIMD数据发送到无线网络。

6. 发明授权

US06473649B1 Rate management during automatic capture verification 有权
标题翻译：自动捕获验证期间的费率管理
公开(公告)号：US06473649B1
公开(公告)日：2002-10-29
申请号：US09470269
申请日：1999-12-22
申请人： Mark Gryzwa , Qingsheng Zhu
发明人： Mark Gryzwa , Qingsheng Zhu
IPC分类号： A61N137
CPC分类号： A61N1/3712 , Y10S128/901
摘要： An implantable cardiac rhythm management device capable of automatically detecting intrinsic and evoked response of a patient's heart and suitable for use during capture verification. The device of the present invention may operate in an automatic capture verification mode, wherein an electrocardiogram signal of a patient's heart is received and used by the device to determine whether a stimulation pulse evokes a response by the patient's heart. The device suspends the automatic capture verification mode and/or adjust the detection threshold dependent upon detected and/or measured noise, a determined amplitude of evoked response, a determined modulation in the evoked response, or detected and/or measured artifact. Further, the sensing circuit of the rhythm management device of the present invention reduces afterpotentials that result due to delivery of the stimulation pulses.
摘要翻译：一种植入式心律管理装置，其能够自动检测患者心脏的内在和诱发反应并适于在捕获验证期间使用。本发明的装置可以在自动捕获验证模式下操作，其中由装置接收并使用患者心脏的心电图信号，以确定刺激脉冲是否引起患者心脏的反应。取决于检测到的和/或测量的噪声，所确定的诱发响应幅度，诱发响应中的确定调制，或检测到的和/或测量的伪影，该装置暂停自动捕获验证模式和/或调整检测阈值。此外，本发明的节律管理装置的感测电路减少了由于刺激脉冲的传送而导致的后电位。

7. 发明申请

US20090063193A1 Dashboard diagnostics for wireless patient communicator 审中-公开
标题翻译：无线患者通讯器的仪表板诊断
公开(公告)号：US20090063193A1
公开(公告)日：2009-03-05
申请号：US12151796
申请日：2008-05-09
申请人： Mike Barton , Rob Parkinson , William Mass , Kenneth Hoyme , David C. Johnson , John LaLonde , Mark Gryzwa , Robert Gaskill
发明人： Mike Barton , Rob Parkinson , William Mass , Kenneth Hoyme , David C. Johnson , John LaLonde , Mark Gryzwa , Robert Gaskill
IPC分类号： G06Q50/00 , G08B1/08
CPC分类号： G08B21/02 , A61B5/0026 , A61B5/0452 , A61B5/747 , A61N1/37211 , A61N1/37282 , G06F19/3418 , G06Q50/24 , G08C17/02 , G16H40/20 , G16H40/40 , H04L67/12 , H04W12/003 , H04W12/04 , H04W12/06
摘要： Portable patient communicators (PPCs) comprise a first radio configured to communicate wirelessly with a patient implantable medical device (PIMD) associated with the PPC and a second radio configured to communicate wirelessly with a network. Memory is configured to store at least first information about wireless connectivity between the PPC and its associated PIMD. A processor is coupled to the memory and the first and second radios. A power source is configured to supply power to components of the PPC. The processor is configured to coordinate discontinuous communication between the PPC and its associated PIMD via the first radio and coordinate discontinuous communication between the PPC and the network via the second radio. The processor is configured to coordinate wireless transmission of the first information to a remote server via the network, and the remote server receives second information about wireless connectivity between each of the PPCs and the network.
摘要翻译：便携式患者通信器（PPC）包括被配置为与PPC相关联的患者可植入医疗设备（PIMD）进行无线通信的第一无线电和被配置为与网络无线通信的第二无线电。存储器被配置为至少存储关于PPC及其相关PIMD之间的无线连接的第一信息。处理器耦合到存储器和第一和第二无线电装置。电源被配置为向PPC的组件供电。处理器被配置为经由第一无线电来协调PPC及其相关PIMD之间的不连续通信，并通过第二无线电协调PPC与网络之间的不连续通信。处理器被配置为经由网络协调第一信息的无线传输到远程服务器，并且远程服务器接收关于每个PPC和网络之间的无线连接的第二信息。

8. 发明申请

US20050065587A1 Implantable lead with magnetic jacket 审中-公开
标题翻译：带有外套的可植入导线
公开(公告)号：US20050065587A1
公开(公告)日：2005-03-24
申请号：US10670156
申请日：2003-09-24
申请人： Mark Gryzwa
发明人： Mark Gryzwa
IPC分类号： A61N1/05 , A61N1/08 , A61N1/16
CPC分类号： A61N1/16 , A61N1/056 , A61N1/08
摘要： An implantable lead assembly includes a lead body extending from a proximal end to a distal, where the lead body has an intermediate portion therebetween. The lead body includes an insulating layer and a conductor disposed within the insulating layer. The insulating layer surrounds the conductor. An electrode is coupled to the lead body, and the electrode is in electrical communication with the conductor. At least one magnetic jacket is disposed within the insulating layer, and the at least one magnetic jacket surrounds the conductor.
摘要翻译：可植入引线组件包括从近端延伸到远端的引线主体，其中引线主体在其间具有中间部分。引线体包括绝缘层和布置在绝缘层内的导体。绝缘层围绕导体。电极耦合到引线体，并且电极与导体电连通。至少一个磁性护套设置在绝缘层内，并且至少一个磁性护套围绕导体。

9. 发明授权

US5941903A Pacemaker for detection of evoked response 失效
标题翻译：起搏器检测诱发反应
公开(公告)号：US5941903A
公开(公告)日：1999-08-24
申请号：US70158
申请日：1998-04-30
申请人： Qingsheng Zhu , Michael Lyden , Scot Boon , Mark Gryzwa
发明人： Qingsheng Zhu , Michael Lyden , Scot Boon , Mark Gryzwa
IPC分类号： A61N1/37
CPC分类号： A61N1/371 , A61N1/3716
摘要： A method and apparatus for attenuating polarization voltages or "afterpotentials" which develop at the heart tissue/electrode interface following the delivery of a pacing stimulus to the heart tissue such that the evoked response of the heart may be accurately detected to determine whether each pacing stimulus resulted in heart capture or contraction, thereby facilitating improved tracking of the capture threshold for minimizing power consumption while assuring therapeutic efficacy. The conventional large capacitance coupling capacitor used to suppress DC components of the pacing pulse is reduced to effectively lower the equivalent capacitance of the pacing and coupling capacitors following delivery of the pacing pulse, allowing shorter recharge and blanking intervals. As a result, the evoked response is more easily detected.
摘要翻译：一种在将起搏刺激递送到心脏组织之后，衰减极化电压或“后电位”的方法和装置，其在心脏组织/电极界面处发展，从而可以精确地检测心脏的诱发反应以确定每个起搏刺激导致心脏捕获或收缩，从而有助于改善捕获阈值的跟踪以最小化功率消耗，同时确保治疗功效。用于抑制起搏脉冲的DC分量的常规大电容耦合电容器被减少以有效地降低起搏脉冲递送后的起搏和耦合电容器的等效电容，从而允许较短的再充电和消隐间隔。结果，更容易检测到诱发反应。

10. 发明授权

US08395498B2 Wireless patient communicator employing security information management 有权
公开(公告)号：US08395498B2
公开(公告)日：2013-03-12
申请号：US12151910
申请日：2008-05-09
申请人： Robert Gaskill , Mark Gryzwa , John LaLonde , Kenneth Hoyme , William Mass , David C. Johnson , Mike Barton
发明人： Robert Gaskill , Mark Gryzwa , John LaLonde , Kenneth Hoyme , William Mass , David C. Johnson , Mike Barton
IPC分类号： G08B1/08
CPC分类号： G08B21/02 , A61B5/0026 , A61B5/0452 , A61B5/747 , A61N1/37211 , A61N1/37282 , G06F19/00 , G06F19/3418 , G06Q50/24 , G08C17/02 , G16H40/20 , G16H40/40 , H04L67/12 , H04W12/04 , H04W12/06
摘要： A portable patient communicator (PPC) includes a portable housing supporting a processor, memory for storing medical and wireless radio firmware, first and second radios, a processor, an identity module, and a power source. The PPC and a patient implantable medical device (PIMD) communicate via the first radio in accordance with the medical firmware. The PPC communicates with a wireless network via the second radio in accordance with the wireless radio firmware. Data stored in the identity module is used to authenticate the PPC by the remote server prior to permitting PPC access to the remote server, and may also be used to authenticate the remote server by the PPC prior to permitting access to the PPC or the PIMD by the remote server or other device communicatively coupled to the wireless network, after which PIMD and other medical data is exchanged between the PPC and remote server.

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