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1. 发明申请

US20050137647A1 Method of intravascularly delivering stimulation leads into direct contact with tissue 失效
标题翻译：血管内传递刺激的方法导致与组织的直接接触
公开(公告)号：US20050137647A1
公开(公告)日：2005-06-23
申请号：US10744853
申请日：2003-12-22
申请人： Michael Wallace , Kamal Ramzipoor , Robert Garabedian , Robert Abrams
发明人： Michael Wallace , Kamal Ramzipoor , Robert Garabedian , Robert Abrams
IPC分类号： A61N1/05 , A61N1/18
CPC分类号： A61N1/0529 , A61N1/0531 , A61N1/0534
摘要： A method of treating a disorder in a patient is provided. The method comprises delivering a stimulation lead within a blood vessel, intralumenally puncturing a wall of the blood vessel to create an exit point, and then introducing the stimulation lead through the exit point into direct contact with tissue the stimulation of which treats the disorder. Optionally, the method comprises implanting a source of stimulation within the patient's body, and then electrically coupling the proximal end of the stimulation lead to the implanted stimulation source. Using the stimulation lead, the tissue can then be stimulated in order to treat the disorder.
摘要翻译：提供了一种治疗患者疾病的方法。该方法包括在血管内递送刺激引线，腔内穿刺血管的壁以产生出口点，然后将刺激引线通过出口点直接接触组织，其刺激治疗病症。可选地，该方法包括将刺激源植入患者体内，然后将刺激引线的近端电耦合到植入的刺激源。使用刺激铅，然后可以刺激组织以治疗该疾病。

2. 发明申请

US20060135986A1 Vaso-occlusive device having pivotable coupling 失效
标题翻译：具有可枢转耦合的血管闭塞装置
公开(公告)号：US20060135986A1
公开(公告)日：2006-06-22
申请号：US11022189
申请日：2004-12-22
申请人： Michael Wallace , Kamal Ramzipoor
发明人： Michael Wallace , Kamal Ramzipoor
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/00477 , A61B2017/12054 , A61B2017/12063 , A61B2017/12095
摘要： An assembly for occluding a vascular site (e.g., an aneurysm) of a human or veterinary patient includes a vaso-occlusive member, a pusher member having a distal end and a severable junction located proximal to the distal end, and a pivotable coupling that couples the pusher member to the occlusive member. A delivery catheter can be used to deliver the vaso-occlusive member to the vascular site. A method of using the assembly to occlude an aneurysm having an aneurysmal sac and an aneurysmal neck, comprises locating the catheter within the aneurysmal neck, and manipulating the pusher member to place the vaso-occlusive member within the aneurysmal sac. The method further comprises severing the severable junction to detach the vaso-occlusive member from the pusher member. As a result, an axial force is applied by the vaso-occlusive member in a proximal direction, which buckles the pivotable coupling to laterally deflect the axial force. The lateral deflection of the axial force caused by the buckling of the pivotable coupling prevents the catheter from being displaced from the aneurysmal neck by the axial force.
摘要翻译：用于闭塞人或兽医患者的血管部位（例如，动脉瘤）的组件包括血管闭塞构件，具有远端的推动器构件和位于远端附近的可分离接合部以及可枢转联接件推动器构件到闭塞构件。输送导管可用于将血管闭塞成员递送至血管部位。一种使用所述组件闭塞具有动脉瘤囊和动脉瘤颈部的动脉瘤的方法，包括将所述导管定位在所述动脉瘤颈内，以及操纵所述推动器构件以将所述血管闭塞构件置于所述动脉瘤囊内。该方法还包括切断可分开的连接点以将血管闭塞构件与推动器构件分离。结果，轴向力由近端方向由血管闭塞构件施加，该近侧方向使可枢转联接器弯曲以横向偏转轴向力。由可枢转联轴器的弯曲引起的轴向力的横向偏转防止导管通过轴向力从动脉瘤颈部移位。

3. 发明申请

US20060271097A1 Electrolytically detachable implantable devices 审中-公开
标题翻译：电解离子可植入装置
公开(公告)号：US20060271097A1
公开(公告)日：2006-11-30
申请号：US11140690
申请日：2005-05-31
申请人： Kamal Ramzipoor , Scott McGill , Michael Wallace , Sarah Young , Russell Ford
发明人： Kamal Ramzipoor , Scott McGill , Michael Wallace , Sarah Young , Russell Ford
IPC分类号： A61M29/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/12113 , A61B2017/12063
摘要： Described herein are electrolytically detachable implantable devices and assemblies. In particular, implantable devices and assemblies that are flexible in or near the electrolytically erodable junction region are provided. Also provided are methods of using the devices and assemblies.
摘要翻译：这里描述的是电解可拆卸的可植入装置和组件。特别地，提供了在电解可腐蚀的接合区域中或其附近柔性的可植入装置和组件。还提供了使用装置和组件的方法。

4. 发明授权

US08298256B2 Apparatus and method for deployment of a therapeutic device using a catheter 失效
标题翻译：使用导管展开治疗装置的装置和方法
公开(公告)号：US08298256B2
公开(公告)日：2012-10-30
申请号：US12814397
申请日：2010-06-11
申请人： Deepak R. Gandhi , Kamal Ramzipoor , Henry N. Padilla
发明人： Deepak R. Gandhi , Kamal Ramzipoor , Henry N. Padilla
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B17/12 , A61B17/12113 , A61B17/1214 , A61B2017/00411 , A61B2017/12068 , A61B2090/037
摘要： The apparatus for deployment of an intravascular therapeutic device, includes an elongated, flexible pusher member and a therapeutic device connected to a severable portion of a first connector member mounted to the flexible pusher member with an elongated second connector member connected to the therapeutic device. The first connector member or second connector member may be capable of being broken by heat, and a heat source is provided for heating and breaking the first connector member or the second connector member to release the therapeutic device.
摘要翻译：用于部署血管内治疗装置的装置包括细长的，柔性的推动器构件和治疗装置，其连接到安装到柔性推动器构件的第一连接器构件的可分离部分，连接到治疗装置的细长的第二连接器构件。第一连接器构件或第二连接器构件可以被热分解，并且提供热源用于加热和断开第一连接器构件或第二连接器构件以释放治疗装置。

5. 发明申请

US20100305605A1 APPARATUS FOR DEPLOYMENT OF MICRO-COIL USING A CATHETER 失效
标题翻译：使用导管分配微卷线的装置
公开(公告)号：US20100305605A1
公开(公告)日：2010-12-02
申请号：US12856496
申请日：2010-08-13
申请人： Deepak Gandhi , Kamal Ramzipoor
发明人： Deepak Gandhi , Kamal Ramzipoor
IPC分类号： A61F2/01
CPC分类号： A61B17/12113 , A61B17/12 , A61B17/12022 , A61B17/12136 , A61B17/1214 , A61B2017/00477 , A61B2017/00867 , A61B2017/12068 , A61B2017/12077 , A61B2017/1209 , A61B2018/00005 , A61B2090/037 , A61F2002/9505 , A61F2002/9511
摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.
摘要翻译：用于展开诸如微型线圈的治疗装置的装置将治疗装置可拆卸地安装到推动器构件的远侧部分。在一个实施例中，治疗装置通过可被诸如电阻线圈的加热器加热的管状套环可拆卸地安装到推动器构件的远端部分，以扩大套环并释放和展开治疗装置。用于展开诸如微型线圈的治疗装置的装置还可以提供用于将治疗装置固定到推动器构件的推动器构件和连接器纤维。连接器纤维通过在推动器构件的远端部分内的加热器，用于加热和断开连接器纤维以在实现治疗装置在脉管系统期望的放置期间释放治疗装置。

6. 发明申请

US20100234935A1 Detachable And Retrievable Stent Assembly 审中-公开
标题翻译：可拆卸支架组件
公开(公告)号：US20100234935A1
公开(公告)日：2010-09-16
申请号：US12792527
申请日：2010-06-02
申请人： Mehran Bashiri , Mark Phung , Kamal Ramzipoor , Ajitkumar B. Nair
发明人： Mehran Bashiri , Mark Phung , Kamal Ramzipoor , Ajitkumar B. Nair
IPC分类号： A61F2/86
CPC分类号： A61F2/90 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/966 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/9528
摘要： A stent assembly comprises an expandable stent having a first stent backbone which extends from the proximal end of the stent to the distal end of the stent. The stent comprises a first stent back bone oriented in a direction which is substantially parallel to a longitudinal axis of the stent, and a plurality of interconnected first stent members and second stent members. Each of the first stent members is oriented in a substantially longitudinal direction in the unexpanded state and the expanded state. Each of the second stent members is oriented in a substantially longitudinal direction in the unexpanded state and oriented in a substantially circumferential direction in the expanded state. The first stent backbone has a greater column strength than that of the plurality of interconnected stent members.
摘要翻译：支架组件包括具有从支架的近端延伸到支架的远端的第一支架主干的可扩张支架。支架包括沿基本上平行于支架的纵向轴线的方向定向的第一支架背骨，以及多个互连的第一支架构件和第二支架构件。第一支架构件中的每一个在未膨胀状态和膨胀状态下在基本纵向方向上定向。每个第二支架构件在未展开状态下沿大致纵向方向定向，并且在膨胀状态下沿大致圆周方向定向。第一支架骨架具有比多个互连的支架构件更大的柱强度。

7. 发明申请

US20090062726A1 MEDICAL IMPLANT DETACHMENT SYSTEMS AND METHODS 有权
标题翻译：医用植入物分离体系及方法
公开(公告)号：US20090062726A1
公开(公告)日：2009-03-05
申请号：US12122636
申请日：2008-05-16
申请人： Russell Ford , Scott McGill , Clifford Teoh , Michael Williams , Kamal Ramzipoor , Like Que , Ann Huang , Elena Oo , Christina Ma , Stella Chu
发明人： Russell Ford , Scott McGill , Clifford Teoh , Michael Williams , Kamal Ramzipoor , Like Que , Ann Huang , Elena Oo , Christina Ma , Stella Chu
IPC分类号： A61B17/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/00022 , A61B2017/12063
摘要： An implant assembly comprises an elongated pusher member, and an implantable device (e.g., a vaso-occlusive device) mounted to the distal end of the pusher member. The implant assembly further comprises an electrolytically severable joint disposed on the pusher member, wherein the implantable device detaches from the pusher member when the severable joint is severed, and a return electrode carried by the distal end of the pusher member (e.g., a coil disposed about the pusher member) in proximity to, but electrically isolated from, the severable joint. The implant assembly further comprises a terminal carried by the proximal end of the pusher member in electrical communication with the severable joint.
摘要翻译：植入物组件包括细长的推动器构件和安装到推动器构件的远端的可植入装置（例如，血管闭塞装置）。植入物组件还包括设置在推动器构件上的电解可分离的接头，其中当可切断接头被切断时，可植入装置与推动器构件分离，以及由推动器构件的远端（例如，线圈设置围绕推动器构件）接近，但是与可分开的接头电隔离。植入物组件还包括由推动器构件的近端承载的端子，其与可分离接头电连通。

8. 发明申请

US20070191879A1 Apparatus for deployment of micro-coil using a catheter 失效
标题翻译：使用导管展开微型线圈的装置
公开(公告)号：US20070191879A1
公开(公告)日：2007-08-16
申请号：US11699308
申请日：2007-01-29
申请人： Deepak Gandhi , Kamal Ramzipoor
发明人： Deepak Gandhi , Kamal Ramzipoor
IPC分类号： A61M29/00
CPC分类号： A61B17/12113 , A61B17/12 , A61B17/12022 , A61B17/12136 , A61B17/1214 , A61B2017/00477 , A61B2017/00867 , A61B2017/12068 , A61B2017/12077 , A61B2017/1209 , A61B2018/00005 , A61B2090/037 , A61F2002/9505 , A61F2002/9511
摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.
摘要翻译：用于展开诸如微型线圈的治疗装置的装置将治疗装置可拆卸地安装到推动器构件的远侧部分。在一个实施例中，治疗装置通过可被诸如电阻线圈的加热器加热的管状套环可拆卸地安装到推动器构件的远端部分，以扩大套环并释放和展开治疗装置。用于展开诸如微型线圈的治疗装置的装置还可以提供用于将治疗装置固定到推动器构件的推动器构件和连接器纤维。连接器纤维通过在推动器构件的远端部分内的加热器，用于加热和断开连接器纤维以在实现治疗装置在脉管系统期望的放置期间释放治疗装置。

9. 发明申请

US20070167911A1 Apparatus and method for deployment of a therapeutic device using a catheter 失效
标题翻译：使用导管展开治疗装置的装置和方法
公开(公告)号：US20070167911A1
公开(公告)日：2007-07-19
申请号：US11726074
申请日：2007-03-21
申请人： Deepak Gandhi , Kamal Ramzipoor
发明人： Deepak Gandhi , Kamal Ramzipoor
IPC分类号： A61B18/14 , A61F11/00 , A61M29/00 , A61F7/12
CPC分类号： A61B17/221 , A61B17/12 , A61B17/12113 , A61B17/1214 , A61B2017/00411 , A61B2017/12068 , A61B2090/037
摘要： The apparatus for deployment of an intravascular therapeutic device, includes an elongated, flexible pusher member and a therapeutic device connected to a severable portion of a first connector member mounted to the flexible pusher member with an elongated second connector member connected to the therapeutic device. The first connector member or second connector member may be capable of being broken by heat, and a heat source is provided for heating and breaking the first connector member or the second connector member to release the therapeutic device.
摘要翻译：用于部署血管内治疗装置的装置包括细长的，柔性的推动器构件和治疗装置，其连接到安装到柔性推动器构件的第一连接器构件的可分离部分，连接到治疗装置的细长的第二连接器构件。第一连接器构件或第二连接器构件可以被热分解，并且提供热源用于加热和断开第一连接器构件或第二连接器构件以释放治疗装置。

10. 发明授权

US07198613B2 Apparatus for deployment of micro-coil using a catheter 有权
公开(公告)号：US07198613B2
公开(公告)日：2007-04-03
申请号：US11020936
申请日：2004-12-22
申请人： Deepak Gandhi , Kamal Ramzipoor
发明人： Deepak Gandhi , Kamal Ramzipoor
IPC分类号： A61F7/12 , A61F11/00 , A61M29/00
CPC分类号： A61B17/12113 , A61B17/12 , A61B17/12022 , A61B17/12136 , A61B17/1214 , A61B2017/00477 , A61B2017/00867 , A61B2017/12068 , A61B2017/12077 , A61B2017/1209 , A61B2018/00005 , A61B2090/037 , A61F2002/9505 , A61F2002/9511
摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.

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