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1. 发明申请

US20070251713A1 Meter base bracket apparatus and system 失效
标题翻译：仪表底座支架设备和系统
公开(公告)号：US20070251713A1
公开(公告)日：2007-11-01
申请号：US11179179
申请日：2005-07-12
申请人： Michael Thornton , Mickey Britain
发明人： Michael Thornton , Mickey Britain
IPC分类号： H01H13/04
CPC分类号： G01R11/04 , H02B1/03 , Y10S248/906
摘要： An electric meter base bracket apparatus and system. Embodiments include a meter bracket installed between studs of a dwelling or structure. The bracket includes several holes to install the bracket to the studs as well as feed-through holes for wiring to the dwelling. Bolts are included on the bracket to attach directly to the meter base. A hole can be cut through the siding so that the meter base and the bracket can connect. An alternative embodiment of the meter base bracket includes a pair of L-brackets that can be co-arranged to form an upper bracket and an additional pair of L-brackets arranged generally parallel to the first pair forming a lower bracket.
摘要翻译：电表底座支架装置及系统。实施例包括安装在住宅或结构的柱之间的仪表支架。支架包括几个孔，用于将支架安装到螺柱上，以及用于连接到住宅的馈通孔。支架上包含螺栓，直接连接到仪表底座。可以通过侧板切割一个孔，以便仪表底座和支架可以连接。仪表底座支架的另一个实施例包括一对L形托架，其可以被共同布置成形成上支架和一对大体上平行于第一对平行布置的左托架，形成下托架。

2. 发明授权

US08728736B2 Methods and compositions for multiplex PCR 有权
标题翻译：多重PCR的方法和组成
公开(公告)号：US08728736B2
公开(公告)日：2014-05-20
申请号：US13619178
申请日：2012-09-14
申请人： John Leamon , Mark Andersen , Michael Thornton
发明人： John Leamon , Mark Andersen , Michael Thornton
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/686 , C12N15/1065 , C12Q1/6806 , C12Q1/6855 , C12Q1/6874 , C12Q1/6886 , C12Q2600/16 , C12Q2521/307 , C12Q2525/101 , C12Q2525/191 , C12Q2537/143
摘要： The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.
摘要翻译：本发明提供可用于样品中存在的一种或多种核酸的多重PCR的方法，组合物，试剂盒，系统和装置。特别地，提供允许一个或多个靶序列的选择性扩增的各种靶特异性引物。一方面，本发明涉及可用于选择性扩增与癌症或遗传性疾病相关的一种或多种靶序列的靶特异性引物。在一些方面，使用所公开的方法，试剂盒，系统和装置获得的扩增靶序列可用于包括核酸测序在内的各种下游过程，并用于检测遗传变体的存在。

3. 发明授权

US08673560B2 Methods and compositions for multiplex PCR 有权
公开(公告)号：US08673560B2
公开(公告)日：2014-03-18
申请号：US13618805
申请日：2012-09-14
申请人： John Leamon , Mark Andersen , Michael Thornton
发明人： John Leamon , Mark Andersen , Michael Thornton
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/686 , C12N15/1065 , C12Q1/6806 , C12Q1/6855 , C12Q1/6874 , C12Q1/6886 , C12Q2600/16 , C12Q2521/307 , C12Q2525/101 , C12Q2525/191 , C12Q2537/143
摘要： The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

4. 发明授权

US08246196B2 Recessed sealed lighting fixture 有权
标题翻译：嵌入式密封照明灯具
公开(公告)号：US08246196B2
公开(公告)日：2012-08-21
申请号：US13104707
申请日：2011-05-10
申请人： Casey Chung , Jill Cody , Brandon Stolte , Marcelino Pena , Michael Thornton
发明人： Casey Chung , Jill Cody , Brandon Stolte , Marcelino Pena , Michael Thornton
IPC分类号： F21S4/00 , F21S8/00 , F21V1/00 , F21V5/00 , F21V7/00 , F21V21/00
CPC分类号： F21V17/164 , F21S8/02 , F21V3/04 , F21V5/02 , F21V15/015 , F21V17/14 , F21W2131/20 , F21Y2103/00 , F21Y2113/00 , Y10T29/49826
摘要： In an embodiment, a recessed light fixture includes a structural reflector and two end caps that form a light fixture housing. A first, second and third optics areas are provided. At least one first light source type is mounted near the first optics area. A second light source type is mounted near the second optics area and the second light source type is mounted near the third optics areas, the second light source type having a light output level substantially lower than the light output level of the first light source type. A diffuser is configured to sealably mount to the light fixture housing so as to substantially seal an interior portion of the light fixture. In operation, the light fixture can be switch between an ambient mode and an examination mode while providing a cost effective and attractive design.
摘要翻译：在一个实施例中，嵌入式灯具包括结构反射器和形成灯具壳体的两个端盖。提供第一，第二和第三光学区域。至少一个第一光源类型安装在第一光学区域附近。第二光源类型安装在第二光学区域附近，第二光源类型安装在第三光学区域附近，第二光源类型的光输出电平基本上低于第一光源类型的光输出电平。扩散器被配置为可密封地安装到灯具壳体，以便基本上密封灯具的内部部分。在操作中，灯具可以在环境模式和检查模式之间切换，同时提供成本有效和有吸引力的设计。

5. 发明申请

US20050186568A1 Kinases and phosphatases 审中-公开
标题翻译：激酶和磷酸酶
公开(公告)号：US20050186568A1
公开(公告)日：2005-08-25
申请号：US10491467
申请日：2002-10-17
申请人： Olga Bandman , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Brooke Emerling , Ian Forsythe , Ameena Ganhi , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Farrah Khan , Preeti Lal , Ernestine Lee , Soo Lee , Erika Lindquist , Dyung Aina Lu , Yan Lu , Joseph Marquis , Danniel Nguyen , Chandra Arvizu , Jayalaxmi Ramkumar , Shirley Recipon , Thomas Richardson , Anita Swarnakar , Y.Tom Tang , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Junming Yang , Monique Yao , Henry Yue , Yeganeh Zebarjadian
发明人： Olga Bandman , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Brooke Emerling , Ian Forsythe , Ameena Ganhi , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Farrah Khan , Preeti Lal , Ernestine Lee , Soo Lee , Erika Lindquist , Dyung Aina Lu , Yan Lu , Joseph Marquis , Danniel Nguyen , Chandra Arvizu , Jayalaxmi Ramkumar , Shirley Recipon , Thomas Richardson , Anita Swarnakar , Y.Tom Tang , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Junming Yang , Monique Yao , Henry Yue , Yeganeh Zebarjadian
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P3/06 , A61P9/00 , A61P25/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07H21/04 , C07K16/46 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/08 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号： C12N9/1205 , A01K2217/05
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译：本发明的各种实施方案提供鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。

6. 发明申请

US20050164275A1 Phosphodiesterases 审中-公开
公开(公告)号：US20050164275A1
公开(公告)日：2005-07-28
申请号：US11048744
申请日：2005-02-03
申请人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
IPC分类号： A01K67/00 , C07H21/04 , C12N9/16 , C12Q1/68
CPC分类号： C12N9/16 , A01K2217/05
摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.

7. 发明授权

US10016147B2 Method and system for estimating the specific absorption rate of a tissue region prior to a magnetic resonance imaging scan 有权
公开(公告)号：US10016147B2
公开(公告)日：2018-07-10
申请号：US14704369
申请日：2015-05-05
申请人： Michael Thornton , Paul Picot , Brian Rutt , Simone Winkler
发明人： Michael Thornton , Paul Picot , Brian Rutt , Simone Winkler
IPC分类号： G01N33/48 , A61B5/055 , G01R33/58 , G01R33/54 , G01R33/28 , A61B5/00 , G06G7/58
CPC分类号： A61B5/055 , A61B5/7225 , G01R33/288 , G01R33/54 , G01R33/58
摘要： A method and system for estimating a specific absorption rate of a tissue region prior to performing a magnetic resonance (MR) imaging scan on the tissue region. The method comprises radiating the tissue region with a plurality of short pulses, wherein the tissue region emits thermoacoustic signals responsive to the short pulses, receiving the thermoacoustic signals by at least one ultrasonic transducer, calculating a temperature rise of the tissue region based on the received thermoacoustic signals, scaling the temperature rise to estimate a temperature rise of the tissue region resulting from an MR imaging scan, and estimating the specific absorption rate of the tissue region based on the estimated temperature rise.

8. 发明申请

US20120293999A1 Recessed Sealed Lighting Fixture 审中-公开
标题翻译：嵌入式密封照明灯具
公开(公告)号：US20120293999A1
公开(公告)日：2012-11-22
申请号：US13560472
申请日：2012-07-27
申请人： Casey Chung , Jill Cody , Brandon Stolte , Marcelino Pena , Michael Thornton
发明人： Casey Chung , Jill Cody , Brandon Stolte , Marcelino Pena , Michael Thornton
IPC分类号： F21V13/02 , B23P11/00 , F21V13/04
CPC分类号： F21V17/164 , F21S8/02 , F21V3/04 , F21V5/02 , F21V15/015 , F21V17/14 , F21W2131/20 , F21Y2103/00 , F21Y2113/00 , Y10T29/49826
摘要： In an embodiment, a recessed light fixture includes a structural reflector and two end caps that form a light fixture housing. A first, second and third optics areas are provided. At least one first light source type is mounted near the first optics area. A second light source type is mounted near the second optics area and the second light source type is mounted near the third optics areas, the second light source type having a light output level substantially lower than the light output level of the first light source type. A diffuser is configured to sealably mount to the light fixture housing so as to substantially seal an interior portion of the light fixture. In operation, the light fixture can be switch between an ambient mode and an examination mode while providing a cost effective and attractive design.
摘要翻译：在一个实施例中，嵌入式灯具包括结构反射器和形成灯具壳体的两个端盖。提供第一，第二和第三光学区域。至少一个第一光源类型安装在第一光学区域附近。第二光源类型安装在第二光学区域附近，第二光源类型安装在第三光学区域附近，第二光源类型的光输出电平基本上低于第一光源类型的光输出电平。扩散器被配置为可密封地安装到灯具壳体，以便基本上密封灯具的内部部分。在操作中，灯具可以在环境模式和检查模式之间切换，同时提供成本有效和有吸引力的设计。

9. 发明授权

US07963662B2 Recessed sealed lighting fixture 有权
标题翻译：嵌入式密封照明灯具
公开(公告)号：US07963662B2
公开(公告)日：2011-06-21
申请号：US12688441
申请日：2010-01-15
申请人： Casey Chung , Jill Cody , Brandon Stolte , Marcelino Pena , Michael Thornton
发明人： Casey Chung , Jill Cody , Brandon Stolte , Marcelino Pena , Michael Thornton
IPC分类号： F21S8/00 , F21S4/00 , F21V1/00 , F21V5/00 , F21V7/00 , F21V21/00
CPC分类号： F21V17/164 , F21S8/02 , F21V3/04 , F21V5/02 , F21V15/015 , F21V17/14 , F21W2131/20 , F21Y2103/00 , F21Y2113/00 , Y10T29/49826
摘要： In an embodiment, a recessed light fixture includes a structural reflector and two end caps that form a light fixture housing. A first, second and third optics areas are provided. At least one first light source type is mounted near the first optics area. A second light source type is mounted near the second optics area and the second light source type is mounted near the third optics areas, the second light source type having a light output level substantially lower than the light output level of the first light source type. A diffuser is configured to sealably mount to the light fixture housing so as to substantially seal an interior portion of the light fixture. In operation, the light fixture can be switch between an ambient mode and an examination mode while providing a cost effective and attractive design.
摘要翻译：在一个实施例中，嵌入式灯具包括结构反射器和形成灯具壳体的两个端盖。提供第一，第二和第三光学区域。至少一个第一光源类型安装在第一光学区域附近。第二光源类型安装在第二光学区域附近，第二光源类型安装在第三光学区域附近，第二光源类型的光输出电平基本上低于第一光源类型的光输出电平。扩散器被配置为可密封地安装到灯具壳体，以便基本上密封灯具的内部部分。在操作中，灯具可以在环境模式和检查模式之间切换，同时提供成本有效和有吸引力的设计。

10. 发明申请

US20070271908A1 Engine exhaust emission control system providing on-board ammonia generation 失效
标题翻译：发动机废气排放控制系统提供车载氨生成
公开(公告)号：US20070271908A1
公开(公告)日：2007-11-29
申请号：US11440930
申请日：2006-05-25
申请人： Mark Hemingway , Brian Christopher , Michael Thornton
发明人： Mark Hemingway , Brian Christopher , Michael Thornton
IPC分类号： F01N3/00 , F01N3/10
CPC分类号： F01N3/0814 , F01N3/0842 , F01N3/0878 , F01N3/2073 , F01N11/00 , F01N13/009 , F01N2240/30 , F01N2410/00 , F01N2560/026 , F01N2610/03 , Y02T10/24 , Y02T10/47
摘要： An exhaust emission control system that provides on-board ammonia generation includes a valve disposed upstream of the LNT and SCR catalyst that operates to selectively control the flow of engine exhaust gas to an LNT and/or an SCR catalyst; while reformate fuel is being conveyed from a reformer to the LNT, the valve operates to cause the exhaust gas to bypass the LNT and flow directly to the SCR catalyst. The exhaust emission control system further includes a controller provided with an algorithm that monitors engine operating conditions and exhaust gas conditions, estimates the cumulative amount of exhaust gas created by the engine and the amount of NOx stored in the LNT, and calculates the amount of NOx required to be converted to NH3.
摘要翻译：提供车载氨生成的废气排放控制系统包括设置在LNT和SCR催化剂的上游的阀，其操作以选择性地控制发动机排气到LNT和/或SCR催化剂的流动; 在将重整燃料从重整器输送到LNT的同时，阀门操作以使废气绕过LNT并直接流向SCR催化剂。废气排放控制系统还包括控制器，该控制器具有监视发动机运转状态和废气条件的算法，估计由发动机产生的排气的累积量和存储在LNT中的NOx的量，并计算NOx的量需要转化为NH 3。

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