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1. 发明申请

US20100197510A1 METHODS FOR RAPID DISEASE SCREENING 审中-公开
标题翻译：快速筛查筛查方法
公开(公告)号：US20100197510A1
公开(公告)日：2010-08-05
申请号：US12529840
申请日：2008-03-07
申请人： Michael Spain , Craig Benson , James P. Mapes , Ralph L. McDade
发明人： Michael Spain , Craig Benson , James P. Mapes , Ralph L. McDade
IPC分类号： C40B30/00
CPC分类号： G01N33/6803
摘要： Methods are provided for screening for the necessity for further diagnosis of one or more diseases or conditions in a subject, which methods are based on the discovery that abnormal levels of selected analytes in a sample fluid from a subject can be correlated with specific diseases or conditions. Further provided are criteria, and methods for the determine thereof, for selected analytes with respect to selected diseases or conditions. Thus, a variety of diseases or conditions can be screened in a rapid, cost-effective composite assay. The methods are useful for screening of newborn humans for a variety of diseases and conditions, whereby additional diagnostic procedures need only be conducted for those diseases or conditions indicated by the methods of the invention.
摘要翻译：提供了筛选用于进一步诊断受试者中一种或多种疾病或病症的必要性的方法，该方法基于以下发现：来自受试者的样品液体中的选定分析物的异常水平可与特定疾病或病症相关。关于所选择的疾病或病症，进一步提供了用于确定所选分析物的标准和方法。因此，可以以快速，成本有效的复合测定法筛选各种疾病或病症。该方法可用于筛选各种疾病和病症的新生儿，由此仅需对本发明方法所指出的那些疾病或病症进行额外的诊断程序。

2. 发明申请

US20050079099A1 Generation of biochemical images and methods of use 审中-公开
标题翻译：生成生化图像和使用方法
公开(公告)号：US20050079099A1
公开(公告)日：2005-04-14
申请号：US10961145
申请日：2004-10-12
申请人： Michael Spain , Craig Benson , Mark Chandler , James Mapes , Ralph McDade
发明人： Michael Spain , Craig Benson , Mark Chandler , James Mapes , Ralph McDade
IPC分类号： G01N33/50 , G06F19/20 , G06F19/26 , G06F19/28 , G06T7/00 , G01N33/48
CPC分类号： G06T7/0012 , G01N33/50 , G16B25/00 , G16B45/00 , G16B50/00
摘要： A biochemical image is derived from specimens, preferably obtained from a statistically relevant sample of a subject population sharing a common characteristic. The biochemical images for one or more conditions present in the subject population and/or one or more test subjects are determined and made available for computer implemented diagnostic evaluations and medical research. In addition to using the information for general research purposes, information from the images may be used to classify diseases and disease states.
摘要翻译：生物化学图像来自标本，优选从具有共同特征的对象群体的统计学相关样品获得。确定主题群体和/或一个或多个测试对象中存在的一个或多个条件的生化图像，并且可用于计算机实施的诊断评估和医学研究。除了将信息用于一般研究目的之外，来自图像的信息可以用于对疾病和疾病状态进行分类。

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