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1. 发明申请

US20110313482A1 SYSTEMS AND METHODS FOR ENHANCED VENOUS RETURN FLOW DURING CARDIAC EVENT 失效
标题翻译：在心脏事件期间增强呼吸流量的系统和方法
公开(公告)号：US20110313482A1
公开(公告)日：2011-12-22
申请号：US13117333
申请日：2011-05-27
申请人： Michael R. Dupelle , Sheldon S. White , Mary Ann Dupelle
发明人： Michael R. Dupelle , Sheldon S. White , Mary Ann Dupelle
IPC分类号： A61N1/36
CPC分类号： A61N1/36014 , A61H31/004 , A61H31/005 , A61H31/007 , A61H2201/1619 , A61H2201/1642 , A61H2201/5061 , A61H2201/5084 , A61H2201/5097 , A61N1/36003 , A61N1/39
摘要： Systems and methods of enhancing cardiopulmonary circulation in a subject during resuscitation are provided. A signal is received responsive to an induced heart compression that is applied to the subject, for example during ventricular fibrillation, an asystolic condition, or cardiac arrest. Responsive to receipt of the signal, a muscle distal subject's heart is electrically stimulated to contract and expel blood into the venous blood flow toward a heart of the subject.
摘要翻译：提供了在复苏期间增强受试者体内心肺循环的系统和方法。响应于施加到受试者的诱导心脏压缩而接收信号，例如在心室颤动期间，收缩期状态或心跳骤停。响应于信号的接收，肌肉远端受试者的心被电刺激以收缩并将血液排出到朝向受试者的心脏的静脉血流中。

2. 发明申请

US20120016361A1 DEPOSIT ABLATION WITHIN AND EXTERNAL TO CIRCULATORY SYSTEMS 审中-公开
标题翻译：在外部循环系统中的沉积物排除
公开(公告)号：US20120016361A1
公开(公告)日：2012-01-19
申请号：US13182104
申请日：2011-07-13
申请人： Sheldon S. White , Michael R. Dupelle , Mary Ann Dupelle
发明人： Sheldon S. White , Michael R. Dupelle , Mary Ann Dupelle
IPC分类号： A61B18/14
CPC分类号： A61N1/32 , A61B2018/0041 , A61N1/0408 , A61N1/20
摘要： Systems and methods of electrical stimulation for intra and extra vascular treatment of a subject are provided. The device includes a first electrode, a second electrode, and a controller. The controller is configured to apply an electrical current between the first and second electrodes. The electrical current follows a path between the first and second electrodes and through a portion of the subject that includes a blockage.
摘要翻译：提供了用于受试者的内部和外部血管治疗的电刺激的系统和方法。该装置包括第一电极，第二电极和控制器。控制器被配置为在第一和第二电极之间施加电流。电流遵循第一和第二电极之间的路径，并且通过包括阻塞的被摄体的一部分。

3. 发明授权

US08527043B2 Systems and methods for enhanced venous return flow during cardiac event 失效
标题翻译：心脏事件期间增强静脉回流的系统和方法
公开(公告)号：US08527043B2
公开(公告)日：2013-09-03
申请号：US13117333
申请日：2011-05-27
申请人： Sheldon S. White , Mary Ann Dupelle
发明人： Michael R. Dupelle , Sheldon S. White
IPC分类号： A61N1/04
CPC分类号： A61N1/36014 , A61H31/004 , A61H31/005 , A61H31/007 , A61H2201/1619 , A61H2201/1642 , A61H2201/5061 , A61H2201/5084 , A61H2201/5097 , A61N1/36003 , A61N1/39
摘要： Systems and methods of enhancing cardiopulmonary circulation in a subject during resuscitation are provided. A signal is received responsive to an induced heart compression that is applied to the subject, for example during ventricular fibrillation, an asystolic condition, or cardiac arrest. Responsive to receipt of the signal, a muscle distal subject's heart is electrically stimulated to contract and expel blood into the venous blood flow toward a heart of the subject.
摘要翻译：提供了在复苏期间增强受试者体内心肺循环的系统和方法。响应于施加到受试者的诱导心脏压缩而接收信号，例如在心室颤动期间，收缩期状态或心跳骤停。响应于信号的接收，肌肉远端受试者的心被电刺激以收缩并将血液排出到朝向受试者的心脏的静脉血流中。

4. 发明授权

US06019877A Protecting medical electrodes from corrosion 失效
标题翻译：保护医用电极免受腐蚀
公开(公告)号：US06019877A
公开(公告)日：2000-02-01
申请号：US99256
申请日：1998-06-18
申请人： Michael R. Dupelle , Deborah T. Jones , Carolyn L. Schmiedeknecht , Sheldon S. White
发明人： Michael R. Dupelle , Deborah T. Jones , Carolyn L. Schmiedeknecht , Sheldon S. White
IPC分类号： A61N1/05 , A61N1/04 , C23F13/00
CPC分类号： A61N1/0492 , A61N1/046
摘要： A medical electrode assembly includes an electrically conductive electrode, an electrically conductive sacrificial element, and a layer of electrically conductive gel. The electrode has an electrical terminal to connect with external electrical circuitry. The sacrificial element is electrically connected with the electrode through an impedance element or a power supply. The layer of electrically conductive gel contacts both the electrode and the sacrificial element so as to form an anode-cathode cell in which the sacrificial element functions as a sacrificial anode that corrodes and the electrode functions as a cathode that is protected from corrosion.
摘要翻译：医疗电极组件包括导电电极，导电牺牲元件和导电凝胶层。电极具有与外部电路连接的电气端子。牺牲元件通过阻抗元件或电源与电极电连接。导电凝胶层接触电极和牺牲元件，以便形成阳极 - 阴极单元，其中牺牲元件用作腐蚀的牺牲阳极，并且电极用作防止腐蚀的阴极。

5. 发明授权

US07269462B2 Medical electrodes with long storage life 有权
标题翻译：医用电极寿命长
公开(公告)号：US07269462B2
公开(公告)日：2007-09-11
申请号：US10608999
申请日：2003-06-27
申请人： Sheldon S. White , Michael R. Dupelle
发明人： Sheldon S. White , Michael R. Dupelle
IPC分类号： A61N1/04
CPC分类号： A61N1/046 , A61N1/0472 , A61N1/0492 , A61N1/0496
摘要： Medical electrodes are provided for use in applications that require long shelf life and/or shelf life at high temperatures. Some electrodes include high temperature adhesives and/or foams and an encapsulated electrolyte.
摘要翻译：提供医用电极用于在高温下需要长保质期和/或保质期的应用。一些电极包括高温粘合剂和/或泡沫和包封的电解质。

6. 发明授权

US06453205B1 Reducing skin damage in use of medical electrodes 有权
标题翻译：减少使用医疗电极时的皮肤损伤
公开(公告)号：US06453205B1
公开(公告)日：2002-09-17
申请号：US09689117
申请日：2000-10-12
申请人： Michael R. Dupelle , Sheldon S. White
发明人： Michael R. Dupelle , Sheldon S. White
IPC分类号： A61N104
CPC分类号： A61N1/046
摘要： A medical electrode assembly includes a conductive electrode, an electrically insulative backing layer on one side of the electrode, an electrically conductive coupling agent in contact with another side of the electrode, an attachment mechanism rigidly connected to a center portion of the electrode, and an electrical conductor connected to the attachment mechanism. The combination of the electrode with the attachment mechanism is constructed with substantial circumferential uniformity such that electrical current provided to the center portion of the electrode through the low-profile attachment mechanism is distributed radially through the electrode in a substantially circumferentially uniform distribution. The electrode is constructed to perform defibrillation or cardioversion. The attachment mechanism is substantially flat and has a low profile. The electrical conductor has a substantially flat, strap-like configuration. A layer of material, which is co-extensive with substantially the entire area of the conductive electrode, causes the insulative backing layer to form a dome while the electrode assembly adheres to a patient's body. In certain embodiments a container surrounds the electrode and the electrically conductive coupling agent. A peel-off layer sealably engages the container through a sealing mechanism. In certain embodiments an electrically conductive sacrificial element is electrically connected with the electrode. The electrically conductive coupling agent contacts the electrode and the sacrificial element, so as to form an anode-cathode cell in which the sacrificial element corrodes and the electrode is protected from corrosion.
摘要翻译：医疗电极组件包括导电电极，电极一侧上的电绝缘背衬层，与电极的另一侧接触的导电耦合剂，刚性地连接到电极的中心部分的附接机构，以及电导体连接到连接机构。电极与附接机构的组合被构造为具有实质的圆周均匀性，使得通过小轮廓附接机构提供到电极的中心部分的电流以基本上周向均匀的分布径向分布穿过电极。构造电极进行除颤或心脏复律。附接机构基本平坦且具有低轮廓。电导体具有基本平坦的带状构造。与导电电极的基本上整个区域共同延伸的材料层使得绝缘背衬层形成圆顶，同时电极组件粘附到患者的身体。在某些实施方案中，容器围绕电极和导电偶联剂。剥离层通过密封机构密封地与容器接合。在某些实施例中，导电牺牲元件与电极电连接。导电偶合剂接触电极和牺牲元件，以形成牺牲元件腐蚀并且电极被保护而不被腐蚀的阳极 - 阴极电池。

7. 发明授权

US06280463B1 Reducing skin damage in use of medical electrodes 有权
标题翻译：减少使用医疗电极时的皮肤损伤
公开(公告)号：US06280463B1
公开(公告)日：2001-08-28
申请号：US09140817
申请日：1998-08-26
申请人： Michael R. Dupelle , Sheldon S. White
发明人： Michael R. Dupelle , Sheldon S. White
IPC分类号： A61N100
CPC分类号： A61N1/046
摘要： A medical electrode assembly includes a conductive electrode, an electrically insulative backing layer on one side of the electrode, an electrically conductive coupling agent in contact with another side of the electrode, an attachment mechanism rigidly connected to a center portion of the electrode, and an electrical conductor connected to the attachment mechanism. The combination of the electrode with the attachment mechanism is constructed with substantial circumferential uniformity such that electrical current provided to the center portion of the electrode through the low-profile attachment mechanism is distributed radially through the electrode in a substantially circumferentially uniform distribution. The electrode is constructed to perform defibrillation or cardioversion. The attachment mechanism is substantially flat and has a low profile. The electrical conductor has a substantially flat, strap-like configuration. A layer of material, which is co-extensive with substantially the entire area of the conductive electrode, causes the insulative backing layer to form a dome while the electrode assembly adheres to a patient's body. In certain embodiments a container surrounds the electrode and the electrically conductive coupling agent. A peel-off layer sealably engages the container through a sealing mechanism. In certain embodiments an electrically conductive sacrificial element is electrically connected with the electrode. The electrically conductive coupling agent contacts the electrode and the sacrificial element, so as to form an anode-cathode cell in which the sacrificial element corrodes and the electrode is protected from corrosion.
摘要翻译：医疗电极组件包括导电电极，电极一侧上的电绝缘背衬层，与电极的另一侧接触的导电耦合剂，刚性地连接到电极的中心部分的附接机构，以及电导体连接到连接机构。电极与附接机构的组合被构造为具有实质的圆周均匀性，使得通过小轮廓附接机构提供到电极的中心部分的电流以基本上周向均匀的分布径向分布穿过电极。构造电极进行除颤或心脏复律。附接机构基本平坦且具有低轮廓。电导体具有基本平坦的带状构造。与导电电极的基本上整个区域共同延伸的材料层使得绝缘背衬层形成圆顶，同时电极组件粘附到患者的身体。在某些实施方案中，容器围绕电极和导电偶联剂。剥离层通过密封机构密封地与容器接合。在某些实施例中，导电牺牲元件与电极电连接。导电偶合剂接触电极和牺牲元件，以形成牺牲元件腐蚀并且电极被保护而不被腐蚀的阳极 - 阴极电池。

8. 发明授权

US08577462B2 Condition sensor for medical device package 失效
标题翻译：医疗器械包装条件传感器
公开(公告)号：US08577462B2
公开(公告)日：2013-11-05
申请号：US11481245
申请日：2006-07-05
申请人： Michael R. Dupelle , Michael Parascandola , Marc Cordaro , Sheldon S. White
发明人： Michael R. Dupelle , Michael Parascandola , Marc Cordaro , Sheldon S. White
IPC分类号： A61N1/00
CPC分类号： A61N1/046 , A61N1/372 , A61N2001/37294
摘要： A package in which a medical device is stored, the package comprising an outer shell providing a vapor barrier, a medical device positioned in the interior space inside the outer shell, the medical device including a liquid-containing element that is subject to drying out, a condition sensor comprising two metallic elements and a conductive water-containing element, each of the two metallic elements being composed of different metals, with each of the different metals selected so that the two metallic elements form an anode and a cathode of an electrochemical cell, so that the water-containing element forms the electrolyte of the electrochemical cell, and the voltage of the cell provides an indication the conductive water-containing element of the medical device has dried out.
摘要翻译：一种其中存储有医疗装置的包装，所述包装包括提供蒸气阻隔物的外壳，位于外壳内部的内部空间中的医疗装置，所述医疗装置包括经受干燥的含液元件，包括两个金属元件和导电含水元件的条件传感器，两个金属元件中的每一个由不同的金属组成，每个不同的金属被选择，使得两个金属元件形成电化学电池的阳极和阴极，使得含水元素形成电化学电池的电解质，并且电池的电压提供医疗装置的导电含水元件是否已经干燥的指示。

9. 发明授权

US07277751B2 ECG/pacing electrodes 有权
标题翻译：心电图/起搏电极
公开(公告)号：US07277751B2
公开(公告)日：2007-10-02
申请号：US10958987
申请日：2004-10-05
申请人： Michael R. Dupelle , Sheldon S. White , Paul Prew
发明人： Michael R. Dupelle , Sheldon S. White , Paul Prew
IPC分类号： A61N1/00
CPC分类号： A61N1/046 , A61N1/3702 , A61N1/39 , A61N1/3925
摘要： A medical electrode assembly comprising a first electrically conductive element configured to be in electrical contact with the patient and to deliver a therapy pulse, a second electrically conductive element configured to be in electrical contact with the patient and to deliver a depolarizing current, and an electrically conductive material providing an electrical connection between the first and second electrically conductive elements and the patient, wherein the first and second electrically conductive elements are configured so that polarization that occurs on the first element as the result of delivery of the therapy pulse may be reduced by subsequent delivery of the depolarizing current, which flows in a circuit that includes the patient and both the first and second conductive elements.
摘要翻译：一种医用电极组件，包括构造成与患者电接触并输送治疗脉冲的第一导电元件，被配置为与患者电接触并传递去极化电流的第二导电元件，以及电在第一和第二导电元件和患者之间提供电连接的导电材料，其中第一和第二导电元件被配置为使得作为治疗脉冲的递送的结果在第一元件上发生的偏振可以通过随后递送在包括患者的电路中流动的去极化电流以及第一和第二导电元件两者。

10. 发明授权

US08064995B1 Pulse sensors 有权
标题翻译：脉冲传感器
公开(公告)号：US08064995B1
公开(公告)日：2011-11-22
申请号：US12874335
申请日：2010-09-02
申请人： Michael R. Dupelle , Paul F. Prew , Sheldon S. White
发明人： Michael R. Dupelle , Paul F. Prew , Sheldon S. White
IPC分类号： A61N1/00
CPC分类号： A61B5/6822 , A61N1/39
摘要： A method of operating an automated external defibrillator, the method being implemented by circuitry and one or more processors of the defibrillator, comprising monitoring a pulse signal from the patient; monitoring an ECG signal from the patient; determining whether it is appropriate to deliver a defibrillation shock to the patient, the determination being based at least in part on the content of the ECG signal and on the content of the pulse signal.
摘要翻译：一种操作自动外部除颤器的方法，该方法由电路和除颤器的一个或多个处理器实现，包括监测来自患者的脉冲信号; 监测来自患者的ECG信号; 确定是否适当地向患者传递除颤电击，该确定至少部分地基于ECG信号的内容和脉冲信号的内容。

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