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1. 发明授权

US06438426B2 Temporary atrial cardioversion catheter 失效
标题翻译：临时心房心脏复律导管
公开(公告)号：US06438426B2
公开(公告)日：2002-08-20
申请号：US09816542
申请日：2001-03-23
申请人： Michael L. Hofstad , John D. Ockuly , Michael J. Coyle , Mark W. Kroll , Steven E. Scott
发明人： Michael L. Hofstad , John D. Ockuly , Michael J. Coyle , Mark W. Kroll , Steven E. Scott
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A coronary sinus catheter includes a distal electrode portion with optimally-spaced and sized ring electrodes and a proximal electrode portion with at least one optimally-spaced and sized larger surface electrode. The catheter has all or some of the following features. First, at least one ring electrode of the distal electrode portion includes a first diameter less than a second diameter of at least one, more proximally disposed, ring electrode of the distal electrode portion. Second, at least one ring electrode of the distal electrode portion includes a first width less than a second width of at least one, more proximally disposed, ring electrode of the distal electrode portion. Third, the distal electrode portion includes at least two ring electrodes and the proximal shock electrode includes at least two larger surface coil electrodes. Fourth, the catheter further includes a collapsible section, adjacent the proximal electrode portion, to facilitate positioning of the catheter within the right atrium.
摘要翻译：冠状窦导管包括具有最佳间隔和尺寸的环形电极的远端电极部分和具有至少一个最佳间隔和尺寸较大的较大表面电极的近端电极部分。导管具有以下所有或一些特征。首先，远端电极部分的至少一个环形电极包括小于远端电极部分的至少一个较近近端的环形电极的第二直径的第一直径。第二，远端电极部分的至少一个环形电极包括小于远侧电极部分的至少一个较近近端的环形电极的第二宽度的第一宽度。第三，远端电极部分包括至少两个环形电极，近端冲击电极包括至少两个较大的表面线圈电极。第四，导管还包括邻近近侧电极部分的可折叠部分，以便于将导管定位在右心房内。

2. 发明授权

US06219582B1 Temporary atrial cardioversion catheter 有权
公开(公告)号：US06219582B1
公开(公告)日：2001-04-17
申请号：US09224257
申请日：1998-12-30
申请人： Michael L. Hofstad , John D. Ockuly , Michael J. Coyle , Mark W. Kroll , Steven E. Scott
发明人： Michael L. Hofstad , John D. Ockuly , Michael J. Coyle , Mark W. Kroll , Steven E. Scott
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A coronary sinus catheter includes a distal electrode portion with optimally-spaced and sized ring electrodes and a proximal electrode portion with at least one optimally-spaced and sized larger surface electrode. The catheter has all or some of the following features. First, at least one ring electrode of the distal electrode portion includes a first diameter less than a second diameter of at least one, more proximally disposed, ring electrode of the distal electrode portion. Second, at least one ring electrode of the distal electrode portion includes a first width less than a second width of at least one, more proximally disposed, ring electrode of the distal electrode portion. Third, the distal electrode portion includes at least two ring electrodes and the proximal shock electrode includes at least two larger surface coil electrodes. Fourth, the catheter further includes a collapsible section, adjacent the proximal electrode portion, to facilitate positioning of the catheter within the right atrium.

3. 发明授权

US06287306B1 Even temperature linear lesion ablation catheter 有权
标题翻译：甚至温度线性病变消融导管
公开(公告)号：US06287306B1
公开(公告)日：2001-09-11
申请号：US09276210
申请日：1999-03-25
申请人： Mark W. Kroll , John D. Ockuly , Rajesh Pendakanti
发明人： Mark W. Kroll , John D. Ockuly , Rajesh Pendakanti
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00363 , A61B2018/00577 , A61B2018/00791
摘要： A linear lesion ablation catheter includes a conductive ablating portion having a predetermined resistivity profile for ablating tissue in a generally even temperature profile. In one embodiment, the conductive ablating portion is disposed on a distal portion of an elongate flexible member and has a resistance that increases exponentially along its length from a center of the ablating portion to a non-infinite value at opposite ends of the ablating portion. The ablating portion is adapted to produce a generally even temperature profile along a length of its surface when the ablating portion is in contact with a target tissue within a patient's body. In one example, the conductive ablating portion comprises a plurality of electrically connected conductive regions which extend from the center to the opposite ends of the ablating portion. Each of the conductive regions has a resistance value wherein the resistance values increase from section to section in successive orders of magnitude from the center of the ablating portion to the opposite ends of the ablating portion exponentially up to a non-infinite value. This predetermined resistivity profile produces linear lesions on target tissue without the resulting “edge effects” or “hot spots” at the ends of the electrode common in prior art linear lesion ablation catheters.
摘要翻译：线性损伤消融导管包括具有预定电阻率分布的导电烧蚀部分，用于在大致均匀的温度分布中烧蚀组织。在一个实施例中，导电烧蚀部分设置在细长柔性构件的远侧部分上，并且具有沿其长度从烧蚀部分的中心指数地增加到消融部分的相对端处的非无限值的电阻。当烧蚀部分与患者体内的靶组织接触时，烧蚀部分适于沿其表面的长度产生大致均匀的温度分布。在一个示例中，导电烧蚀部分包括从烧蚀部分的中心延伸到相对端的多个电连接的导电区域。每个导电区域具有电阻值，其中电阻值从烧蚀部分的中心到烧蚀部分的相对端的指数地增加到非无穷大的连续数量级，从而逐段增加。这种预定的电阻率分布在靶组织上产生线性损伤，而不会在现有技术的线性损伤消融导管中常见的电极末端产生“边缘效应”或“热点”。

4. 发明授权

US06780181B2 Even temperature linear lesion ablation catheter 有权
标题翻译：甚至温度线性病变消融导管
公开(公告)号：US06780181B2
公开(公告)日：2004-08-24
申请号：US09941522
申请日：2001-08-29
申请人： Mark W. Kroll , John D. Ockuly , Rajesh Pendakanti
发明人： Mark W. Kroll , John D. Ockuly , Rajesh Pendakanti
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00363 , A61B2018/00577 , A61B2018/00791
摘要： A linear lesion ablation catheter includes a conductive ablating portion having a predetermined resistivity profile for ablating tissue in a generally even temperature profile. In one embodiment, the conductive ablating portion is disposed on a distal portion of an elongate flexible member and has a resistance that increases exponentially along its length from a center of the ablating portion to a non-infinite value at opposite ends of the ablating portion. The ablating portion is adapted to produce a generally even temperature profile along a length of its surface when the ablating portion is in contact with a target tissue within a patient's body. In one example, the conductive ablating portion comprises a plurality of electrically connected conductive regions which extend from the center to the opposite ends of the ablating portion. Each of the conductive regions has a resistance value wherein the resistance values increase from section to section in successive orders of magnitude from the center of the ablating portion to the opposite ends of the ablating portion exponentially up to a non-infinite value. This predetermined resistivity profile produces linear lesions on target tissue without the resulting “edge effects” or “hot spots” at the ends of the electrode common in prior art linear lesion ablation catheters.
摘要翻译：线性损伤消融导管包括具有预定电阻率分布的导电烧蚀部分，用于以大致均匀的温度分布消融组织。在一个实施例中，导电烧蚀部分设置在细长柔性构件的远侧部分上，并且具有沿其长度从烧蚀部分的中心指数地增加到消融部分的相对端处的非无限值的电阻。当烧蚀部分与患者体内的靶组织接触时，烧蚀部分适于沿其表面的长度产生大致均匀的温度分布。在一个示例中，导电烧蚀部分包括从烧蚀部分的中心延伸到相对端的多个电连接的导电区域。每个导电区域具有电阻值，其中电阻值从烧蚀部分的中心到烧蚀部分的相对端的指数地增加到非无穷大的连续数量级，从而逐段增加。这种预定的电阻率分布在靶组织上产生线性损伤，而不会在现有技术的线性损伤消融导管中常见的电极末端产生“边缘效应”或“热点”。

5. 发明授权

US06447507B1 Rail catheter ablation and mapping system 失效
标题翻译：轨道导管消融和绘图系统
公开(公告)号：US06447507B1
公开(公告)日：2002-09-10
申请号：US09498139
申请日：2000-02-04
申请人： Michael C. Bednarek , John F. Swartz , Michael J. Coyle , John D. Ockuly , James A. Hassett
发明人： Michael C. Bednarek , John F. Swartz , Michael J. Coyle , John D. Ockuly , James A. Hassett
IPC分类号： A61B1814
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2018/00029 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/1407 , A61B2018/1437 , A61B2018/1472 , A61B2218/002 , A61M25/0041 , A61M25/0662 , C08L2201/12
摘要： An ablation system for ablating cardiac tissue within a chamber of the human heart including a guiding introducer system, a rail, one end of which is contained within the guiding introducer system, and an ablation catheter system which is supported by the guiding introducer system. The guiding introducer system may be a single or multiple guiding introducers. The ablation system may include a slotted sheath which passes over the rail which supports the ablation catheter. A process is disclosed for ablation of cardiac tissue to form a linear lesion utilizing a rail catheter ablation and mapping system which includes a guiding introducer, a rail and an ablation catheter system advanced over the rail.
摘要翻译：一种用于在人心腔内消融心脏组织的消融系统，包括引导导引器系统，导轨，其一端容纳在引导导引器系统内，轨道由引导导引器系统支撑。导向引导器系统可以是单个或多个引导引导器。消融系统可以包括穿过支撑消融导管的轨道的开槽护套。公开了一种利用轨道导管消融和绘图系统消融心脏组织以形成线性病变的方法，其包括在导轨上前进的引导引导器，导轨和消融导管系统。

6. 发明授权

US6120500A Rail catheter ablation and mapping system 失效
公开(公告)号：US6120500A
公开(公告)日：2000-09-19
申请号：US968414
申请日：1997-11-12
申请人： Michael C. Bednarek , John F. Swartz , Michael J. Coyle , John D. Ockuly , James A. Hassett
发明人： Michael C. Bednarek , John F. Swartz , Michael J. Coyle , John D. Ockuly , James A. Hassett
IPC分类号： A61N1/18 , A61B18/00 , A61B18/14 , A61B18/16 , A61M25/00 , A61M25/01 , A61M25/06 , A61M25/08 , A61B17/39 , A61B5/042 , A61N1/05
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2018/00029 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/1407 , A61B2018/1437 , A61B2018/1472 , A61B2218/002 , A61M25/0041 , A61M25/0662 , C08L2201/12
摘要： An ablation system for ablating cardiac tissue within a chamber of the human heart including a guiding introducer system, a rail, one end of which is contained within the guiding introducer system, and an ablation catheter system which is supported by the guiding introducer system. The guiding introducer system may be a single or multiple guiding introducers. The ablation system may include a slotted sheath which passes over the rail which supports the ablation catheter. A process is disclosed for ablation of cardiac tissue to form a linear lesion utilizing a rail catheter ablation and mapping system which includes a guiding introducer, a rail and an ablation catheter system advanced over the rail.

7. 发明授权

US5810730A Guiding introducer for right atrium 失效
公开(公告)号：US5810730A
公开(公告)日：1998-09-22
申请号：US392057
申请日：1995-02-22
申请人： John Frederick Swartz , John D. Ockuly , John J. Fleischhacker , James A. Hassett
发明人： John Frederick Swartz , John D. Ockuly , John J. Fleischhacker , James A. Hassett
IPC分类号： A61B17/00 , A61M25/00 , A61M25/01 , A61M25/06 , A61N1/05 , A61B6/00
CPC分类号： A61N1/057 , A61M25/0041 , A61M25/01 , A61M25/0662 , A61M25/0133
摘要： A guiding introducer for use in the right atrium comprised of a first, second and third section wherein the first section is a generally elongated straight section wherein merged with the distal end of the first section is a second section which is curved upward in a longitudinal curve wherein the distal end of the second section is merged with the third section. The guiding introducer is for use in sensing, pacing and ablating procedures in the right atrium of the human heart.

8. 发明授权

US5715818A Method of using a guiding introducer for left atrium 失效
标题翻译：使用引导引导器进行左心房的方法
公开(公告)号：US5715818A
公开(公告)日：1998-02-10
申请号：US551173
申请日：1995-10-31
申请人： John Frederick Swartz , John D. Ockuly , John J. Fleischhacker , James A. Hassett
发明人： John Frederick Swartz , John D. Ockuly , John J. Fleischhacker , James A. Hassett
IPC分类号： A61M25/08 , A61M25/00 , A61M25/01 , A61M25/06 , A61N1/05 , A61B5/00
CPC分类号： A61N1/057 , A61M25/0041 , A61M25/0133 , A61M25/0662
摘要： A guiding introducer for use in the left atrium comprised of a first, second and third section wherein the first section is a generally elongated straight section wherein merged with the distal end of the first section is a second section which is curved in a compound curve, first curving upward in a first longitudinal curve and simultaneously curving to the right in a second longitudinal curve, wherein the second section merges with the third section wherein said third section is a third longitudinal curve wherein the plane of the third section is angled upward at an angle of approximately 25 to about 60 degrees from the plane of the first section and wherein substantially all of the third section is coplanar.
摘要翻译：一种用于左心房的引导引导器，包括第一部分，第二部分和第三部分，其中第一部分是大致细长的直部分，其中与第一部分的远端合并的是第二部分，其在复合曲线中弯曲，首先在第一纵向曲线向上弯曲并且在第二纵向曲线中同时向右弯曲，其中第二部分与第三部分合并，其中所述第三部分是第三纵向曲线，其中第三部分的平面在从第一部分的平面大约25至大约60度的角度，并且其中基本上所有的第三部分是共面的。

9. 发明授权

US06458107B1 Steerable coronary sinus catheter 有权
标题翻译：可导向冠状窦导管
公开(公告)号：US06458107B1
公开(公告)日：2002-10-01
申请号：US09440631
申请日：1999-11-15
申请人： John D. Ockuly
发明人： John D. Ockuly
IPC分类号： A61M2500
CPC分类号： A61M25/0054 , A61M25/0041 , A61M2025/0081
摘要： A steerable catheter for insertion into the ostium of the coronary sinus in the right atria including a flexible catheter body, and a steerable catheter handle wherein the catheter body includes a generally straight proximal section, a deflectable distal section and a precurved tip portion located at a distal end of the deflectable distal section. Preferably, the precurved tip portion curves outside of a plane formed by the deflectable distal section from about 20 degrees to about 50 degrees.
摘要翻译：一种用于插入右心房中的冠状窦的口中的可导向的导管，包括柔性导管主体和可导向的导管手柄，其中导管主体包括大致直的近端部分，可偏转的远端部分和位于可偏转远端部分的远端。优选地，预先的尖端部分从可偏转的远端部分形成的平面的外侧弯曲约20度至约50度。

10. 发明授权

US5879296A Guiding introducers for use in the treatment of left ventricular tachycardia 失效
标题翻译：引导者用于治疗左心室心动过速
公开(公告)号：US5879296A
公开(公告)日：1999-03-09
申请号：US800287
申请日：1997-02-12
申请人： John D. Ockuly , James A. Hassett
发明人： John D. Ockuly , James A. Hassett
IPC分类号： A61B18/12 , A61B8/12 , A61M25/00 , A61M25/01 , A61M25/06 , A61M25/08 , A61N1/05 , H04L29/12 , A61B5/04 , A61B17/39
CPC分类号： A61M25/0041 , A61N1/057 , A61M25/0133 , A61M25/0662 , H04L29/12207 , H04L61/20
摘要： A process for the treatment of ventricular tachycardia in the left ventricle using a retrograde approach by use of ablation and/or mapping catheters guided by precurved guiding introducers. Also disclosed are predetermined shapes for the guiding introducers to be used for the treatment of ventricular tachycardia in the left ventricle using a retrograde approach.
摘要翻译：一种使用逆行方法在左心室治疗室性心动过速的方法，其通过使用由预先引导引导器引导的消融和/或定位导管。还公开了用于使用逆行方法用于治疗左心室心室性心动过速的引导引导器的预定形状。

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