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1. 发明授权

US06719718B2 Thrombectomy catheter and system 失效
公开(公告)号：US06719718B2
公开(公告)日：2004-04-13
申请号：US09930794
申请日：2001-08-16
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B1720
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.

2. 发明授权

US06764483B1 Thrombectomy catheter and system 失效
公开(公告)号：US06764483B1
公开(公告)日：2004-07-20
申请号：US09915875
申请日：2001-07-26
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61M5178
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.

3. 发明授权

US06945951B1 Thrombectomy catheter and system 失效
标题翻译：血栓切除导管及系统
公开(公告)号：US06945951B1
公开(公告)日：2005-09-20
申请号：US09930796
申请日：2001-08-16
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B17/22 , A61B17/32 , A61M1/00 , A61B17/20
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.
摘要翻译：交叉流血栓切除术导管和用于从血管或其他体腔破裂和去除血栓或其他材料的系统。从导管远端的环形环喷射发生器或其他喷射发射器发射的高速盐水喷射器通过流入孔夹带流体，并且流动阻力产生背压，该背压驱动跨径流通过径向流出孔，并周向地将正常和牵引力施加在血管或其它体腔中的血栓形成沉积物或病变上，从而分离和输送通过流入孔夹带的血栓颗粒，于是高速喷射器将血栓颗粒浸入，排气腔或再次通过外流孔再循环。

4. 发明授权

US06805684B2 Thrombectomy catheter and system 失效
公开(公告)号：US06805684B2
公开(公告)日：2004-10-19
申请号：US09930795
申请日：2001-08-16
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B1720
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.

5. 发明授权

US06676627B1 Crossflow thrombectomy catheter and system 失效
标题翻译：血栓切除导管及系统
公开(公告)号：US06676627B1
公开(公告)日：2004-01-13
申请号：US09417395
申请日：1999-10-13
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B1720
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.
摘要翻译：交叉流血栓切除术导管和用于从血管或其他体腔破裂和去除血栓或其他材料的系统。从导管远端的环形环喷射发生器或其他喷射发射器发射的高速盐水喷射器通过流入孔夹带流体，并且流动阻力产生背压，该背压驱动跨径流通过径向流出孔，并周向地将正常和牵引力施加在血管或其它体腔中的血栓形成沉积物或病变上，从而分离和输送通过流入孔夹带的血栓颗粒，于是高速喷射器将血栓颗粒浸入，排气腔或再次通过外流孔再循环。

6. 发明授权

US07169161B2 Guidewire having occlusive device and repeatably crimpable proximal end 有权
标题翻译：导丝具有闭塞装置和可重复卷曲的近端
公开(公告)号：US07169161B2
公开(公告)日：2007-01-30
申请号：US10012891
申请日：2001-11-06
申请人： Michael J. Bonnette , Eric J. Thor , Mark L. Jenson , Rick C. Kravic , Hieu V. Le
发明人： Michael J. Bonnette , Eric J. Thor , Mark L. Jenson , Rick C. Kravic , Hieu V. Le
IPC分类号： A61M25/10
CPC分类号： A61M25/10184 , A61M25/09 , A61M25/10185 , A61M2025/09008
摘要： A tubular guidewire assembly having a distal occlusive device and an extended crimpable section proximate a proximal end that is adapted to connect to a gas inflation/evacuation system. The extended crimpable section can be selectively sealed at one of a plurality of separate locations to form an airtight seal of the tubular guidewire assembly. Each time a deflation of the occlusive device is desired in order to reestablish blood flow to a vessel downstream of the occlusive device, the extended crimpable section preferably is cut distal to the location of the last seal to quickly deflate the occlusive device.
摘要翻译：一种管状导丝组件，其具有远端闭塞装置和靠近近端的伸缩卷曲部分，其适于连接到气体充气/抽空系统。扩展的可卷曲部分可以选择性地密封在多个分开的位置中的一个处，以形成管状导丝组件的气密密封。每次需要闭塞装置的放气以便重新建立到闭塞装置下游的血管的血液流动时，伸出的可卷曲部分优选地被切割到最后密封的位置的远侧，以快速地缩小闭塞装置。

7. 发明授权

US06942678B2 Gas inflation/evacuation system and sealing system for guidewire assembly having occlusive device 失效
标题翻译：用于具有闭塞装置的导丝组件的气体充气/排气系统和密封系统
公开(公告)号：US06942678B2
公开(公告)日：2005-09-13
申请号：US10007788
申请日：2001-11-06
申请人： Michael J. Bonnette , Eric J. Thor , Mark L. Jenson
发明人： Michael J. Bonnette , Eric J. Thor , Mark L. Jenson
IPC分类号： A61F2/958 , A61M25/10
CPC分类号： A61M25/10184 , A61M25/09 , A61M25/10185 , A61M25/104 , A61M29/02 , A61M39/06 , A61M2025/09008
摘要： A gas inflation/evacuation system and sealing system for use with occlusive devices such as occlusive balloons in vascular procedures. The gas inflation/evacuation system is removably connectible to a proximal portion of a guidewire assembly and includes an evacuation system to evacuate the guidewire assembly and an inflation system for introducing a biocompatible gas under pressure into the guidewire assembly to inflate an occlusive device a plurality of times. A sealing system is also removably connectible to the proximal portion of the guidewire assembly and selectively seals an extended sealable section at the proximal portion of the guidewire assembly at one of a plurality of separate locations to form an airtight seal of the guidewire assembly. Each time a deflation of the occlusive device is desired in order to reestablish blood flow to the vessel downstream of the occlusive device, the extended sealable section at the proximal portion of the guidewire assembly preferably is cut distal to the location of the last seal to quickly deflate the occlusive device.
摘要翻译：用于闭塞装置的气体充气/抽空系统和密封系统，例如血管手术中的闭塞气囊。气体充气/抽空系统可移除地连接到导丝组件的近端部分，并且包括抽空系统以抽出导丝组件和用于将压力下的生物相容性气体引入导丝组件的膨胀系统，以使闭塞装置多个次密封系统也可移除地连接到导丝组件的近端部分，并且在多个分开的位置之一处选择性地密封导丝组件的近端部分处的延伸的可密封部分，以形成导丝组件的气密密封。每次需要闭塞装置的放气以便重新建立到闭塞装置下游的血管的血流时，导丝组件的近端部分处的延伸的可密封部分优选地被切割成远离最后密封的位置，以快速放气闭塞装置。

8. 发明授权

US07334681B2 Packaging system with oxygen sensor for gas inflation/evacuation system and sealing system 失效
标题翻译：用于气体充气/抽空系统和密封系统的氧气传感器的包装系统
公开(公告)号：US07334681B2
公开(公告)日：2008-02-26
申请号：US11654741
申请日：2007-01-18
申请人： Michael J. Bonnette , Eric J. Thor , Mark L. Jenson
发明人： Michael J. Bonnette , Eric J. Thor , Mark L. Jenson
IPC分类号： B65D85/20 , A61M25/10
CPC分类号： A61M25/002 , A61M25/0009 , A61M25/10182 , A61M25/10184 , A61M25/10185 , A61M2025/09008 , B65D79/02 , B65D81/2076 , Y10S206/807 , Y10T436/207497
摘要： A storable gas inflation/evacuation system and sealing system. The systems are removably connectible to a proximal portion of a guidewire assembly which has an occlusive balloon at a distal portion. The invention includes provision for indicating the presence of oxygen which is undesirable. The storable aspect concerns a sealable container isolating systems components from ambient atmosphere and an oxygen-sensitive material located within the sealable container. The oxygen-sensitive material is initially inactive but activated by exposure to radiation so as to visually change in response to post-radiation oxygen exposure.
摘要翻译：可储存的气体充气/排气系统和密封系统。该系统可拆卸地连接到导丝组件的近端部分，导丝组件在远侧部分具有闭塞气囊。本发明包括用于指示不合乎需要的氧的存在。可存储的方面涉及可密封的容器，隔离系统部件与环境大气和位于可密封容器内的氧敏感材料。氧敏感材料最初是无活性的，但是通过暴露于辐射而被激活，以便根据后辐射氧暴露而视觉上改变。

9. 发明授权

US09254124B2 Self-orientating suture wound closure device 有权
标题翻译：自定向缝合伤口闭合装置
公开(公告)号：US09254124B2
公开(公告)日：2016-02-09
申请号：US12026207
申请日：2008-02-05
申请人： William J. Drasler , Tracee Eidenschink , Joseph M. Thielen , Mark L. Jenson , Anu Sadasiva
发明人： William J. Drasler , Tracee Eidenschink , Joseph M. Thielen , Mark L. Jenson , Anu Sadasiva
IPC分类号： A61B17/04 , A61B17/00 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0057 , A61B17/0469 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/047 , A61B2017/0472 , A61B2017/3484 , A61B2090/067 , A61B2090/0811
摘要： A device is disclosed for providing an indication as to the relative position of a vessel or artery opening thereby facilitating the choice of which several closure techniques to use. A disclosed device includes an outer tube and a collapsible foot slidably disposed within a distal end of the outer tube. The device may further include one or more threaded suture needles, a biodegradable plug or other wound closing device that is connected to another shaft. The collapsed or folded foot is pushed distally out of the tube and through the opening in the vessel whereupon the foot expands. Pulling the expanded foot in the proximal direction provides an indication as to the orientation of the opening in the vessel, which assists in determining the type of closing procedure to be carried out.
摘要翻译：公开了一种用于提供关于血管或动脉开口的相对位置的指示的装置，从而便于选择使用哪些闭合技术。所公开的装置包括外管和可滑动地设置在外管的远端内的可折叠的脚。该装置还可以包括一个或多个螺纹缝合针，可生物降解的塞子或其它连接到另一轴的闭合装置。折叠或折叠的脚从管中向远侧推出并穿过容器中的足部膨胀的开口。沿着近端方向拉动扩张的脚提供关于容器中的开口的取向的指示，这有助于确定要执行的关闭程序的类型。

10. 发明授权

US09044350B2 Alignment sheath apparatus and method 有权
标题翻译：对准护套装置及方法
公开(公告)号：US09044350B2
公开(公告)日：2015-06-02
申请号：US11507103
申请日：2006-08-21
申请人： Mark L. Jenson , William J. Drasler , Tracee Eidenschink
发明人： Mark L. Jenson , William J. Drasler , Tracee Eidenschink
IPC分类号： A61F2/954 , A61F2/856 , A61F2/86 , A61F2/852 , A61F2/06
CPC分类号： A61F2/856 , A61F2/852 , A61F2/86 , A61F2/954 , A61F2002/067 , A61F2220/005 , A61F2220/0058 , A61F2230/001 , A61F2230/0043 , A61F2250/006
摘要： The invention is direction to an alignment apparatus comprising a central sheath, an alignment sheath, and at least one stent. The central sheath and the alignment sheath each have a wall and a distal end where the wall of the alignment sheath is engaged to the wall of the central sheath. The wall of the central sheath defines a central lumen that has a central guide wire extending therethrough and the wall of the alignment sheath defines an alignment lumen that has an alignment guide wire extending therethrough. The distal end of the alignment sheath is positioned proximally to the distal end of the central sheath. The alignment apparatus has at least one stent disposed about one of the alignment guide wire or the central guide wire. The at least one stent has a pre-delivered state so that when the at least one stent is in the pre-delivered state, it is contained within at least one of the central sheath and the alignment sheath.
摘要翻译：本发明是包括中心护套，对准护套和至少一个支架的对准装置的方向。中心护套和对准护套均具有壁和远端，其中对准护套的壁与中心护套的壁接合。中心护套的壁限定了具有延伸穿过其中的中心导丝的中心管，并且对准护套的壁限定了具有延伸穿过其中的对准导丝的对准内腔。对准护套的远端位于中央护套的远端的近侧。对准装置具有至少一个支架，其布置在对准引导线或中心引导线之一附近。至少一个支架具有预输送状态，使得当至少一个支架处于预输送状态时，其被包含在至少一个中心护套和对准护套中。

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