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1. 发明申请

US20100174143A1 DUAL SEAL WITH BELLOWS 审中-公开
标题翻译：双重密封与BELLOWS
公开(公告)号：US20100174143A1
公开(公告)日：2010-07-08
申请号：US12628609
申请日：2009-12-01
申请人： Michael E. Abrams , Christopher A. Battles , Paul DiCesare , Danial P. Ferreira , Gregory R. Hires
发明人： Michael E. Abrams , Christopher A. Battles , Paul DiCesare , Danial P. Ferreira , Gregory R. Hires
IPC分类号： A61B1/00
CPC分类号： A61B17/3462 , A61B2017/3445 , A61B2017/3449 , A61B2017/3466
摘要： A seal assembly which includes a housing defining a longitudinal axis, a proximal portion and a distal portion and including a bellows disposed along a length thereof. A first sealing membrane and a second sealing membrane associated with the proximal portion of the housing, each sealing membrane configured to create a substantially fluid-tight seal around a surgical instrument inserted therethrough. The bellows configured to allow at least a portion of the housing to move radially with respect to the longitudinal axis.
摘要翻译：一种密封组件，其包括限定纵向轴线的壳体，近侧部分和远侧部分，并且包括沿其长度设置的波纹管。与壳体的近侧部分相关联的第一密封膜和第二密封膜，每个密封膜构造成围绕插入其中的外科器械产生基本上流体密封的密封。波纹管被配置成允许壳体的至少一部分相对于纵向轴线径向移动。

2. 发明授权

US07736593B2 Device and methods for collection of biological fluid sample and treatment of selected components 有权
标题翻译：用于收集生物流体样品和处理所选组分的装置和方法
公开(公告)号：US07736593B2
公开(公告)日：2010-06-15
申请号：US10912263
申请日：2004-08-05
申请人： Ajit N. Dastane , Dimitrios Manoussakis , Christopher A. Battles , Paul DiCesare , Jeffrey Radziunas
发明人： Ajit N. Dastane , Dimitrios Manoussakis , Christopher A. Battles , Paul DiCesare , Jeffrey Radziunas
IPC分类号： G01N1/18
CPC分类号： B01L3/50825 , A61B5/15003 , A61B5/150236 , A61B5/150251 , A61B5/150351 , A61B5/150755 , A61B5/154 , A61B5/417 , A61B10/0045 , B01F13/002 , B01F15/00512 , B01L3/50215 , B01L2200/16 , B01L2300/042 , B01L2300/047 , B01L2300/0609 , B01L2400/0683 , G01N33/491 , Y10T428/13 , Y10T436/25375 , Y10T436/255
摘要： A collection device and a method for collecting a biological sample, particularly whole blood, includes a separating member to separate the whole blood into its components, and at least reagent positioned to selectively interact with a component of the separated sample. The reagent is able to selectively interact with the plasma/serum, and is prevented from contacting or interacting with the whole blood.
摘要翻译：收集装置和用于收集生物样品，特别是全血的收集装置和方法包括分离构件，以将全血分离成其组分，并且至少包含试剂，定位成选择性地与分离的样品的组分相互作用。试剂能够选择性地与血浆/血清相互作用，并且被阻止与全血接触或相互作用。

3. 发明授权

US08449479B2 Squeeze activated medical puncturing device 有权
标题翻译：挤压激活的医疗穿刺装置
公开(公告)号：US08449479B2
公开(公告)日：2013-05-28
申请号：US11568603
申请日：2005-04-29
申请人： Jeffrey Radzuinas , Paul DiCesare , Christopher A. Battles
发明人： Jeffrey Radzuinas , Paul DiCesare , Christopher A. Battles
IPC分类号： A61B5/00
CPC分类号： A61B5/150832 , A61B5/150022 , A61B5/150259 , A61B5/150412 , A61B5/150442 , A61B5/150503 , A61B5/150564 , A61B5/150618 , A61B5/150717 , A61B5/150885 , A61B5/15111 , A61B5/15117 , A61B5/1513 , A61B5/15144
摘要： The medical puncturing device (10) includes a housing (12) having a proximal end (18) and a distal end (16) and a skin puncturing assembly (14) within the housing. The skin puncturing assembly includes a movable carrier (50) and a skin puncturing element (52). The skin puncturing element is adapted to puncture the skin of a patient. The carrier is movable from a retracted position wherein a distal tip of the skin puncturing element is disposed within the housing, to a puncturing position wherein the distal tip is exposed to puncture the skin of the patient. The carrier is moved from the retracted position to the puncturing position upon radial deformation of the housing. An internal guide (42) may be provided within the housing for guiding the movement of the carrier from the retracted position to the puncturing position.
摘要翻译：医疗穿刺装置（10）包括在壳体内具有近端（18）和远端（16）以及皮肤穿刺组件（14）的壳体（12）。皮肤穿刺组件包括可移动的载体（50）和皮肤穿刺元件（52）。皮肤穿刺元件适于穿刺患者的皮肤。所述托架可以从缩回位置移动，其中所述皮肤穿刺元件的远侧末端设置在所述外壳内，到达穿刺位置，其中所述远端尖端暴露以刺穿所述患者的皮肤。当壳体径向变形时，托架从缩回位置移动到穿刺位置。内部引导件（42）可以设置在壳体内，用于将托架的运动从缩回位置引导到穿刺位置。

4. 发明申请

US20110112438A1 Squeeze Activated Medical Puncturing Device 有权
标题翻译：挤压活化医疗穿刺装置
公开(公告)号：US20110112438A1
公开(公告)日：2011-05-12
申请号：US11568603
申请日：2005-04-29
申请人： Jeffrey Radzuinas , Paul DiCesare , Christopher A. Battles
发明人： Jeffrey Radzuinas , Paul DiCesare , Christopher A. Battles
IPC分类号： A61B5/151
CPC分类号： A61B5/150832 , A61B5/150022 , A61B5/150259 , A61B5/150412 , A61B5/150442 , A61B5/150503 , A61B5/150564 , A61B5/150618 , A61B5/150717 , A61B5/150885 , A61B5/15111 , A61B5/15117 , A61B5/1513 , A61B5/15144
摘要： The medical puncturing device (10) includes a housing (12) having a proximal end (18) and a distal end (16) and a skin puncturing assembly (14) within the housing. The skin puncturing assembly includes a movable carrier (50) and a skin puncturing element (52). The skin puncturing element is adapted to puncture the skin of a patient. The carrier is movable from a retracted position wherein a distal tip of the skin puncturing element is disposed within the housing, to a puncturing position wherein the distal tip is exposed to puncture the skin of the patient. The carrier is moved from the retracted position to the puncturing position upon radial deformation of the housing. An internal guide (42) may be provided within the housing for guiding the movement of the carrier from the retracted position to the puncturing position.
摘要翻译：医疗穿刺装置（10）包括在壳体内具有近端（18）和远端（16）以及皮肤穿刺组件（14）的壳体（12）。皮肤穿刺组件包括可移动的载体（50）和皮肤穿刺元件（52）。皮肤穿刺元件适于穿刺患者的皮肤。所述托架可以从缩回位置移动，其中所述皮肤穿刺元件的远侧末端设置在所述外壳内，到达穿刺位置，其中所述远端尖端暴露以刺穿所述患者的皮肤。当壳体径向变形时，托架从缩回位置移动到穿刺位置。内部引导件（42）可以设置在壳体内，用于将托架的运动从缩回位置引导到穿刺位置。

5. 发明授权

US09283361B2 Implantable drug delivery devices for genitourinary sites 有权
标题翻译：用于泌尿生殖部位的植入式药物输送装置
公开(公告)号：US09283361B2
公开(公告)日：2016-03-15
申请号：US13813745
申请日：2011-08-03
申请人： Paul DiCesare , Jeffrey Radziunas , Andrew Barnes , Eric Britschock , David Sutton
发明人： Paul DiCesare , Jeffrey Radziunas , Andrew Barnes , Eric Britschock , David Sutton
IPC分类号： A61M31/00
CPC分类号： A61M31/002
摘要： Implantable drug delivery devices are provided lo have a deployment shape for implantation in the body and a retention shape for retention in the body. The device may have one or more elongated drug reservoirs containing a drug, mid the drug reservoir may be formed from a deformable material. In one case, a first filament is attached to the first end of the drug reservoir and second filament is attached to the second end of the drug reservoir, wherein a fastener is positioned about the first and second filaments to permit shortening and prevent lengthening of the filaments with reference to the ends of the daig reservoir, as a means for transforming the device from the implantation shape to the retention shape.
摘要翻译：可植入药物递送装置具有用于植入体内的展开形状和用于保持在体内的保持形状。该装置可以具有包含药物的一个或多个细长的药物储存器，药物储存器的中部可以由可变形材料形成。在一种情况下，第一丝被附着到药物储存器的第一端并且第二丝连接到药物储存器的第二端，其中紧固件围绕第一和第二长丝定位以允许缩短和防止延长参考daig储存器的端部的细丝作为将装置从植入形状转换成保持形状的手段。

6. 发明授权

US07740616B2 Implantable catheter and method of using same 有权
标题翻译：可植入导管及其使用方法
公开(公告)号：US07740616B2
公开(公告)日：2010-06-22
申请号：US11392257
申请日：2006-03-29
申请人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
发明人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
IPC分类号： A61M25/02
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter for implantation into a patient having a catheter tube having a distal end, a means for trimming the distal end of the catheter tube after subcutaneous insertion of the tip of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube. The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端的导管的患者的导管，用于在将导管内腔的尖端皮下插入患者体内的期望位置之后修整导管管的远端的装置，以形成修剪的端部以及用于选择性地定位导管管的修剪端部的每个相应内腔与一个附接管的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

7. 发明申请

US20060241661A1 Devices and methods for fastening tissue layers 有权
公开(公告)号：US20060241661A1
公开(公告)日：2006-10-26
申请号：US11471513
申请日：2006-06-21
申请人： Robert DeVries , William Shaw , Kristian Dimatteo , Gerhard Buess , Daniel Kalanovic , Marc Schurr , Roy Sullivan , Marc Tassy , John Griego , Patrick Gutileus , Paul DiCesare
发明人： Robert DeVries , William Shaw , Kristian Dimatteo , Gerhard Buess , Daniel Kalanovic , Marc Schurr , Roy Sullivan , Marc Tassy , John Griego , Patrick Gutileus , Paul DiCesare
IPC分类号： A61B17/08
CPC分类号： A61B17/08 , A61B1/2736 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06109 , A61B17/0643 , A61B17/068 , A61B17/10 , A61B17/29 , A61B2017/00827 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/061 , A61B2017/081 , A61B2017/306
摘要： Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The device may include, for example, an elongated tubular member having a proximal end for extending outside of the body and a distal end for positioning proximate the multiple tissue layers, a grasper configured for positioning proximate the distal end of the tubular member and for grasping at least one of the multiple tissue layers, a device coupled to the distal end of the tubular member for folding the multiple tissue layers together, a tissue fastener configured to be inserted into the tissue layers to hold the tissue layers together, and a fastener head for inserting the tissue fastener into the tissue layers.

8. 发明申请

US20050149077A1 Devices and methods for performing a vascular anastomosis 审中-公开
标题翻译：用于进行血管吻合的装置和方法
公开(公告)号：US20050149077A1
公开(公告)日：2005-07-07
申请号：US11059169
申请日：2005-02-16
申请人： Hanson Gifford , Lee Bolduc , Jeffrey Stein , Paul DiCesare , Peter Costa , William Holmes
发明人： Hanson Gifford , Lee Bolduc , Jeffrey Stein , Paul DiCesare , Peter Costa , William Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00 , A61B17/08
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis
摘要翻译：一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触靶容器的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合

9. 外观设计

USD475135S1 Disposable scalpel 失效
标题翻译：一次性手术刀
公开(公告)号：USD475135S1
公开(公告)日：2003-05-27
申请号：US29156378
申请日：2002-02-28
申请人： Glade Harold Howell , Simon Cohn , Charles Hwang , John R. Montgomery , Paul DiCesare
设计人： Glade Harold Howell , Simon Cohn , Charles Hwang , John R. Montgomery , Paul DiCesare
CPC分类号： A61B17/3211 , A61B2017/32113

10. 外观设计

USD470587S1 Disposable scalpel 失效
公开(公告)号：USD470587S1
公开(公告)日：2003-02-18
申请号：US29156380
申请日：2002-02-28
申请人： Glade Harold Howell , Simon Cohn , Charles Hwang , John D. Montgomery , Paul DiCesare
设计人： Glade Harold Howell , Simon Cohn , Charles Hwang , John D. Montgomery , Paul DiCesare
CPC分类号： A61B17/3211 , A61B2017/32113

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