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1. 发明申请

US20100100074A1 IMPLANTABLE CATHETHER AND METHOD OF USING SAME 有权
标题翻译：可植入的导管及其使用方法
公开(公告)号：US20100100074A1
公开(公告)日：2010-04-22
申请号：US12643562
申请日：2009-12-21
申请人： A. DAVID SMITH , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
发明人： A. DAVID SMITH , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
IPC分类号： A61M25/16 , A61B17/3209
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter for implantation into a patient having a catheter tube having a distal end, a means for trimming the distal end of the catheter tube after subcutaneous insertion of the tip of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube. The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端的导管的患者的导管，用于在将导管内腔的尖端皮下插入患者体内的期望位置之后修整导管管的远端的装置，以形成修剪的端部以及用于选择性地定位导管管的修剪端部的每个相应内腔与一个附接管的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

2. 发明授权

US07740616B2 Implantable catheter and method of using same 有权
标题翻译：可植入导管及其使用方法
公开(公告)号：US07740616B2
公开(公告)日：2010-06-22
申请号：US11392257
申请日：2006-03-29
申请人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
发明人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
IPC分类号： A61M25/02
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter for implantation into a patient having a catheter tube having a distal end, a means for trimming the distal end of the catheter tube after subcutaneous insertion of the tip of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube. The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端的导管的患者的导管，用于在将导管内腔的尖端皮下插入患者体内的期望位置之后修整导管管的远端的装置，以形成修剪的端部以及用于选择性地定位导管管的修剪端部的每个相应内腔与一个附接管的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

3. 发明授权

US07905875B2 Implantable catheter and method of using same 有权
标题翻译：可植入导管及其使用方法
公开(公告)号：US07905875B2
公开(公告)日：2011-03-15
申请号：US12643562
申请日：2009-12-21
申请人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
发明人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
IPC分类号： A61M31/00
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter for implantation into a patient having a catheter tube having a distal end, a means for trimming the distal end of the catheter tube after subcutaneous insertion of the tip of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube. The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端的导管的患者的导管，用于在将导管内腔的尖端皮下插入患者体内的期望位置之后修整导管管的远端的装置，以形成修剪的端部以及用于选择性地定位导管管的修剪端部的每个相应内腔与一个附接管的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

4. 发明授权

US09283361B2 Implantable drug delivery devices for genitourinary sites 有权
标题翻译：用于泌尿生殖部位的植入式药物输送装置
公开(公告)号：US09283361B2
公开(公告)日：2016-03-15
申请号：US13813745
申请日：2011-08-03
申请人： Paul DiCesare , Jeffrey Radziunas , Andrew Barnes , Eric Britschock , David Sutton
发明人： Paul DiCesare , Jeffrey Radziunas , Andrew Barnes , Eric Britschock , David Sutton
IPC分类号： A61M31/00
CPC分类号： A61M31/002
摘要： Implantable drug delivery devices are provided lo have a deployment shape for implantation in the body and a retention shape for retention in the body. The device may have one or more elongated drug reservoirs containing a drug, mid the drug reservoir may be formed from a deformable material. In one case, a first filament is attached to the first end of the drug reservoir and second filament is attached to the second end of the drug reservoir, wherein a fastener is positioned about the first and second filaments to permit shortening and prevent lengthening of the filaments with reference to the ends of the daig reservoir, as a means for transforming the device from the implantation shape to the retention shape.
摘要翻译：可植入药物递送装置具有用于植入体内的展开形状和用于保持在体内的保持形状。该装置可以具有包含药物的一个或多个细长的药物储存器，药物储存器的中部可以由可变形材料形成。在一种情况下，第一丝被附着到药物储存器的第一端并且第二丝连接到药物储存器的第二端，其中紧固件围绕第一和第二长丝定位以允许缩短和防止延长参考daig储存器的端部的细丝作为将装置从植入形状转换成保持形状的手段。

5. 发明授权

US07736593B2 Device and methods for collection of biological fluid sample and treatment of selected components 有权
标题翻译：用于收集生物流体样品和处理所选组分的装置和方法
公开(公告)号：US07736593B2
公开(公告)日：2010-06-15
申请号：US10912263
申请日：2004-08-05
申请人： Ajit N. Dastane , Dimitrios Manoussakis , Christopher A. Battles , Paul DiCesare , Jeffrey Radziunas
发明人： Ajit N. Dastane , Dimitrios Manoussakis , Christopher A. Battles , Paul DiCesare , Jeffrey Radziunas
IPC分类号： G01N1/18
CPC分类号： B01L3/50825 , A61B5/15003 , A61B5/150236 , A61B5/150251 , A61B5/150351 , A61B5/150755 , A61B5/154 , A61B5/417 , A61B10/0045 , B01F13/002 , B01F15/00512 , B01L3/50215 , B01L2200/16 , B01L2300/042 , B01L2300/047 , B01L2300/0609 , B01L2400/0683 , G01N33/491 , Y10T428/13 , Y10T436/25375 , Y10T436/255
摘要： A collection device and a method for collecting a biological sample, particularly whole blood, includes a separating member to separate the whole blood into its components, and at least reagent positioned to selectively interact with a component of the separated sample. The reagent is able to selectively interact with the plasma/serum, and is prevented from contacting or interacting with the whole blood.
摘要翻译：收集装置和用于收集生物样品，特别是全血的收集装置和方法包括分离构件，以将全血分离成其组分，并且至少包含试剂，定位成选择性地与分离的样品的组分相互作用。试剂能够选择性地与血浆/血清相互作用，并且被阻止与全血接触或相互作用。

6. 发明申请

US20060241661A1 Devices and methods for fastening tissue layers 有权
公开(公告)号：US20060241661A1
公开(公告)日：2006-10-26
申请号：US11471513
申请日：2006-06-21
申请人： Robert DeVries , William Shaw , Kristian Dimatteo , Gerhard Buess , Daniel Kalanovic , Marc Schurr , Roy Sullivan , Marc Tassy , John Griego , Patrick Gutileus , Paul DiCesare
发明人： Robert DeVries , William Shaw , Kristian Dimatteo , Gerhard Buess , Daniel Kalanovic , Marc Schurr , Roy Sullivan , Marc Tassy , John Griego , Patrick Gutileus , Paul DiCesare
IPC分类号： A61B17/08
CPC分类号： A61B17/08 , A61B1/2736 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06109 , A61B17/0643 , A61B17/068 , A61B17/10 , A61B17/29 , A61B2017/00827 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/061 , A61B2017/081 , A61B2017/306
摘要： Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The device may include, for example, an elongated tubular member having a proximal end for extending outside of the body and a distal end for positioning proximate the multiple tissue layers, a grasper configured for positioning proximate the distal end of the tubular member and for grasping at least one of the multiple tissue layers, a device coupled to the distal end of the tubular member for folding the multiple tissue layers together, a tissue fastener configured to be inserted into the tissue layers to hold the tissue layers together, and a fastener head for inserting the tissue fastener into the tissue layers.

7. 发明申请

US20050149077A1 Devices and methods for performing a vascular anastomosis 审中-公开
标题翻译：用于进行血管吻合的装置和方法
公开(公告)号：US20050149077A1
公开(公告)日：2005-07-07
申请号：US11059169
申请日：2005-02-16
申请人： Hanson Gifford , Lee Bolduc , Jeffrey Stein , Paul DiCesare , Peter Costa , William Holmes
发明人： Hanson Gifford , Lee Bolduc , Jeffrey Stein , Paul DiCesare , Peter Costa , William Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00 , A61B17/08
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis
摘要翻译：一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触靶容器的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合

8. 外观设计

USD475135S1 Disposable scalpel 失效
标题翻译：一次性手术刀
公开(公告)号：USD475135S1
公开(公告)日：2003-05-27
申请号：US29156378
申请日：2002-02-28
申请人： Glade Harold Howell , Simon Cohn , Charles Hwang , John R. Montgomery , Paul DiCesare
设计人： Glade Harold Howell , Simon Cohn , Charles Hwang , John R. Montgomery , Paul DiCesare
CPC分类号： A61B17/3211 , A61B2017/32113

9. 外观设计

USD470587S1 Disposable scalpel 失效
公开(公告)号：USD470587S1
公开(公告)日：2003-02-18
申请号：US29156380
申请日：2002-02-28
申请人： Glade Harold Howell , Simon Cohn , Charles Hwang , John D. Montgomery , Paul DiCesare
设计人： Glade Harold Howell , Simon Cohn , Charles Hwang , John D. Montgomery , Paul DiCesare
CPC分类号： A61B17/3211 , A61B2017/32113

10. 发明授权

US06497325B1 Device for separating components of a fluid sample 有权
标题翻译：用于分离流体样品的组分的装置
公开(公告)号：US06497325B1
公开(公告)日：2002-12-24
申请号：US09454267
申请日：1999-12-03
申请人： Paul DiCesare , Jeffrey Karg , Fu-Chung Lin
发明人： Paul DiCesare , Jeffrey Karg , Fu-Chung Lin
IPC分类号： B01D2126
CPC分类号： B01L3/50215
摘要： A device and method is provided for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents. The constituents include a container, a liner in the container and a composite element in the liner for separating the fractions of a fluid sample. The separator comprises a specific density at a target density range as defined by separable fluid components densities. A fluid sample is delivered to the liner and then the device is subjected to centrifugation whereby the centrifugal load causes the liner to deform and the composite element migrates into the fluid sample and stabilizes between the heavier and lighter fractions of the fluid sample. The liner will resiliently return to its initial configuration upon termination of the centrifugal load such that the liner sealingly engages the composite element and separates the heavier and lighter fractions of the fluid sample.
摘要翻译：提供了用于分离流体样品的较重和较轻馏分的装置和方法。该装置包括多个成分。组分包括容器，容器中的衬垫和用于分离流体样品的级分的衬垫中的复合元件。分离器包括由可分离的流体组分密度所限定的目标密度范围的特定密度。将流体样品输送到衬套，然后使装置进行离心，由此离心负载导致衬套变形，并且复合元件迁移到流体样品中并且在流体样品的较重和较轻部分之间稳定。衬垫将在离心负载终止时弹性地返回到其初始构型，使得衬套密封地接合复合元件并分离流体样品的较重和较轻的部分。

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