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    • 6. 发明授权
    • Particulate encapsulation of liquid beads
    • 液体珠的颗粒包封
    • US06413548B1
    • 2002-07-02
    • US09568272
    • 2000-05-10
    • Monica A. HamerJames J. MartiWilliam A. Hendrickson
    • Monica A. HamerJames J. MartiWilliam A. Hendrickson
    • A61K914
    • A61K8/11A61K8/25A61K8/676A61K9/501A61K9/5031A61K9/5089A61K2800/412A61Q19/00B01J13/02Y10T428/2984Y10T428/2985Y10T428/2991Y10T428/2998
    • Various materials, including generally non-compatible materials may be provided from a single delivery system by a unique encapsulation system. An encapsulation system is advantageously constructed as a core of aqueous liquid having at least 5% by weight water therein, and an encapsulant surrounding the core to form a stable encapsulated particle, the encapsulant comprising at least one layer of hydrophobic particles in contact with and surrounding the core, the core and hydrophobic particles providing an encapsulated system that has an average weight average particle diameter of from 0.05 to 25 micrometers and can support its own weight. The encapsulation system may be provided by a novel method of manufacture comprising providing a mass of hydrophobic particles having average mass diameter size of between 0.05 and 25 micrometers, providing droplets of an aqueous medium to the mass of particles, gently mixing the fine particles of aqueous medium and the hydrophobic particles to form a stable encapsulant system of droplets of the aqueous medium encapsulated by a shell of particles.
    • 可以通过独特的封装系统从单个递送系统提供各种材料,包括通常不兼容的材料。 封装系统有利地被构造为具有至少5重量%水中的水的含水液体的核心,以及包围核心以形成稳定的包封颗粒的密封剂,所述密封剂包含至少一层与所述疏水性颗粒接触并包围 芯,芯和疏水性颗粒提供具有0.05至25微米的平均重量平均粒径并且可以支撑其自身重量的封装体系。 包封系统可以通过一种新的制造方法提供,包括提供大量平均质量直径尺寸为0.05至25微米的疏水性颗粒,向颗粒物质提供水性介质的液滴,轻轻地将水性微粒 介质和疏水颗粒以形成由颗粒壳包封的水性介质的液滴的稳定的密封剂系统。
    • 8. 发明授权
    • Process for patterning powders into thick layers
    • 将粉末图案化成厚层的方法
    • US5817374A
    • 1998-10-06
    • US656089
    • 1996-05-31
    • Robert H. DetigWilliam A. Hendrickson
    • Robert H. DetigWilliam A. Hendrickson
    • B05C19/00B05D1/00B05D1/32B05D5/06D21H19/68D21H23/50D21H23/64H05K3/10B05D1/06
    • B05C19/00B05D1/007B05D1/32B05D5/067D21H19/68H05K3/102D21H23/50D21H23/64
    • Particles are applied to the surfaces of materials, especially in the form of discontinuous or patterned coatings on the surfaces of sheet materials by a process comprising the steps of: a) providing a support, b) placing a bed of non-adhered particles on the support, the particles being capable of being moved by an electric field of less than 100 KV/cm, c) placing a mask with a first and second surface over the bed of non-adhered particles, the mask having holes which pass from the first to the second surface, the first surface facing the bed of non-adhered particles without the mask touching the bed of non-adhered particles, the holes in the mask having a size which would allow passage of individual particles from the bed of non-adhered particles through the holes, d) placing a receptor material capable of at least temporarily retaining an electric charge adjacent to the second surface of the mask, which second surface faces away from the bed of non-adhered particles, e) applying an electrical charge to the receptor material which is at least temporarily retained by the receptor material, f) applying an electrical field between the mask and the support, the electrical field being of at least sufficient strength to cause individual particles from the bed of non-adhered particles to move off the first substrate and impact the mask, g) allowing some of the individual particles which move off of the support to enter the holes in the mask and contact the receptor material, and h) the contract by individual particles to the receptor material causing at least some of the particles contacting the receptor material to adhere to the receptor material at least by charge attraction of the individual particles to charge on the receptor material.
    • 颗粒通过包括以下步骤的方法施加到材料的表面,特别是以不连续或图案化的涂层的形式,其包括以下步骤:a)提供载体,b)将非粘附颗粒床放置在 支撑,能够通过小于100KV / cm的电场移动的颗粒,c)将具有第一和第二表面的掩模放置在非附着颗粒的床上,所述掩模具有从第一 到第二表面,第一表面面向非附着颗粒床,而不用掩模接触非粘附颗粒床,掩模中的孔具有允许单个颗粒从未粘附的床通过的尺寸 颗粒通过孔,d)放置能够至少暂时保持与掩模的第二表面相邻的电荷的受体材料,该第二表面背离非附着颗粒的床,e) 对受体材料至少暂时保持的受体材料的电荷,f)在掩模和支撑体之间施加电场,电场至少具有足够的强度,以使来自未粘附床的单个颗粒 颗粒离开第一基底并撞击掩模,g)允许从载体移出的一些单个颗粒进入掩模中的孔并接触受体材料,以及h)单个颗粒对受体的收缩 使至少一些与受体材料接触的颗粒的材料至少通过各个颗粒的电荷吸引而附着到受体材料上,以对受体材料充电。