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1. 发明授权

US07224411B2 Digital projection equipment and techniques 有权
标题翻译：数字投影设备和技术
公开(公告)号：US07224411B2
公开(公告)日：2007-05-29
申请号：US09980068
申请日：2001-05-30
申请人： Michael A. Gibbon , Samuel Z. Zhou , Graham H. Moss , Dermot J. Quinn , Steven Wilding , Brian Eckersley , Sean Adkins , Sergei G. Anikitchev , Steven Read
发明人： Michael A. Gibbon , Samuel Z. Zhou , Graham H. Moss , Dermot J. Quinn , Steven Wilding , Brian Eckersley , Sean Adkins , Sergei G. Anikitchev , Steven Read
IPC分类号： H04N5/74
CPC分类号： H04N9/317 , G02B27/1066 , G02B27/143 , G02B27/283 , G03B21/008 , G03B21/2013 , G03B21/2073
摘要： Apparatus and techniques for enhancing characteristics of electronic projection systems are detailed. Included among the techniques are both superimposition of sub-images and tiling of superimposed images, the combination of which can be advantageous in improving resolution of projected images. Pre-modulators and polarizing beam splitters also may be used as parts of the innovative systems.
摘要翻译：详细说明了用于增强电子投影系统特性的装置和技术。这些技术中包括的是副图像的叠加和叠加的图像的平铺，其组合可以有利于提高投影图像的分辨率。预调制器和偏振分束器也可用作创新系统的一部分。

2. 发明授权

US07224335B2 DMD-based image display systems 有权
标题翻译：基于DMD的图像显示系统
公开(公告)号：US07224335B2
公开(公告)日：2007-05-29
申请号：US10220626
申请日：2001-03-15
申请人： Michael A. Gibbon , Steven Read , Samuel Ziheng Zhou , Sean Adkins
发明人： Michael A. Gibbon , Steven Read , Samuel Ziheng Zhou , Sean Adkins
IPC分类号： G09G3/34
CPC分类号： G09G3/346 , G09G1/06 , G09G3/001 , G09G3/2014 , G09G3/2018 , G09G2300/02 , G09G2310/0235 , G09G2320/0261 , G09G2340/0428 , H04N5/7416 , H04N5/7458 , H04N9/3105 , H04N9/3123 , H04N9/3126
摘要： A projection system having a controller and a plurality of reflective SLMs operatively coupled to the controller to receive image data from the controller. The reflective SLMs arc aligned in series to receive light form a light source and to reflect imaging light correlated to the image data.
摘要翻译：一种具有控制器和多个反射SLM的投影系统，可操作地耦合到控制器以从控制器接收图像数据。反射SLM串联对准以接收来自光源的光并反射与图像数据相关的成像光。

3. 发明授权

US06919990B2 Methods and systems for low loss separation and combination of light 有权
标题翻译：低损耗分离和光组合的方法和系统
公开(公告)号：US06919990B2
公开(公告)日：2005-07-19
申请号：US10258995
申请日：2001-04-18
申请人： Serguei G. Anikitchev , Steven Read , Graham H. Moss
发明人： Serguei G. Anikitchev , Steven Read , Graham H. Moss
IPC分类号： G02B27/10 , H04N5/74 , H04N9/31 , G02B27/14 , G03B21/00 , G09G3/14
CPC分类号： G02B27/143 , G02B27/1026 , G02B27/126 , G02B27/144 , H04N5/7416 , H04N5/7458 , H04N9/3105
摘要： A display system is disclosed that includes a light source, an integrator rod receiving a light beam from the light source and producing an integrated light beam, a beam splitting device splitting the integrated light beam into at least a first cone of light and a second cone of light, the cones of light having complementary intensity distributions, and at least a first spatial light modulator and a second spatial light modulator, wherein the first spatial light modulator is capable of selectively reflecting portions of the first cone of light in an ON direction and the second spatial light modulator is capable of selectively reflecting portions of the second cone of light in an ON direction. The display system further includes a combining device for combining the selectively reflected portions of the cones of light in the ON direction and projection optics for projecting the combined reflected cones of light.
摘要翻译：公开了一种显示系统，其包括光源，接收来自光源的光束并产生集成光束的积分器杆，将所述集成光束分成至少第一光锥和第二锥体的分束装置的光，具有互补强度分布的光的锥形，以及至少第一空间光调制器和第二空间光调制器，其中第一空间光调制器能够选择性地反射第一锥形光在ON方向上的部分，第二空间光调制器能够选择性地反射第二光锥的部分在ON方向上。该显示系统还包括一个组合装置，用于将ON方向上的锥形光纤的选择反射部分与用于投射组合的反射光锥的投影光学装置组合。

4. 发明申请

US20140228251A1 siRNA Targeting Catenin, Beta-1 (CTNNB1) 有权
标题翻译： siRNA靶向联蛋白，β-1（CTNNB1）
公开(公告)号：US20140228251A1
公开(公告)日：2014-08-14
申请号：US13764825
申请日：2013-02-12
申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
发明人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
IPC分类号： C07H21/02
CPC分类号： C12N15/00 , C12N15/113 , C12N15/1135 , C12N2310/14 , C12N2320/11 , C12N2320/31
摘要： Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for CTNNB1.
摘要翻译：通过使用siRNA技术，有效的序列特异性基因沉默是可能的。通过合理设计选择特定的siRNA，可以最大限度地产生有效的基因沉默试剂，以及沉默基因的方法。公开了通过合理设计siRNA产生的方法，组合物和试剂盒，包括针对CTNNB1的核苷酸序列的那些。

5. 发明授权

US08567953B2 Systems and methods for projecting composite images 有权
标题翻译：用于投影复合图像的系统和方法
公开(公告)号：US08567953B2
公开(公告)日：2013-10-29
申请号：US11912524
申请日：2006-04-26
申请人： Matthew O'Dor , Steven Read , Anton Baljet , Philip Insull
发明人： Matthew O'Dor , Steven Read , Anton Baljet , Philip Insull
IPC分类号： H04N13/04 , G03B21/14
CPC分类号： G09G5/377 , G06T15/00 , H04N9/3147 , H04N13/324 , H04N13/327 , H04N13/337 , H04N13/359 , H04N13/363
摘要： Embodiments of the present invention comprise electronic projection systems and methods. One embodiment of the present invention comprises a method of creating composite images with a projection system comprising a first projector and at least a second projector, comprising generating a correspondence map of pixels for images by determining offsets between pixels from at least a second image from the second projector and corresponding pixels from a first image from the first projector, receiving a source image, warping the source image based at least in part on the correspondence map to produce a warped image, and displaying the source image by the first projector and displaying the warped image by the second projector to create a composite image.
摘要翻译：本发明的实施例包括电子投影系统和方法。本发明的一个实施例包括一种用包括第一投影仪和至少第二投影仪的投影系统创建合成图像的方法，包括通过确定来自所述图像的至少第二图像的像素之间的偏移来生成图像的像素的对应图，第二投影仪和来自第一投影仪的第一图像的对应像素，接收源图像，至少部分地基于对应图来扭曲源图像以产生翘曲图像，以及通过第一投影仪显示源图像，由第二台投影机翘曲的图像创建一个合成图像。

6. 发明申请

US20130023446A1 siRNA Targeting Beta Secretase (BACE) 审中-公开
标题翻译： siRNA靶向β分泌酶（BACE）
公开(公告)号：US20130023446A1
公开(公告)日：2013-01-24
申请号：US13613910
申请日：2012-09-13
申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
发明人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
IPC分类号： C07H21/02 , C40B40/06
CPC分类号： C12N15/113 , C12N15/111 , C12N15/1135 , C12N2310/11 , C12N2310/14 , C12N2320/11 , G16B20/00
摘要： Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for BACE.
摘要翻译：通过使用siRNA技术，有效的序列特异性基因沉默是可能的。通过合理设计选择特定的siRNA，可以最大限度地产生有效的基因沉默试剂，以及沉默基因的方法。公开了通过合理设计siRNA产生的方法，组合物和试剂盒，包括针对BACE的核苷酸序列的那些。

7. 发明授权

US08304528B2 SiRNA targeting fructose-1, 6-bisphosphatase 1 (FBP1) 有权
标题翻译：靶向果糖-1,6-二磷酸酶1（FBP1）的SiRNA
公开(公告)号：US08304528B2
公开(公告)日：2012-11-06
申请号：US12592872
申请日：2009-12-03
申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
发明人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04
CPC分类号： C12N15/113 , C12N15/111 , C12N15/1135 , C12N2310/11 , C12N2310/14 , C12N2320/11 , G06F19/18
摘要： Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for FBP1.
摘要翻译：通过使用siRNA技术，有效的序列特异性基因沉默是可能的。通过合理设计选择特定的siRNA，可以最大限度地产生有效的基因沉默试剂，以及沉默基因的方法。公开了通过合理设计siRNA产生的方法，组合物和试剂盒，包括针对FBP1的核苷酸序列的那些。

8. 发明申请

US20120270751A1 siRNA Targeting Diacylglycerol O-Acyltransferase Homolog 2 (DGAT2) 审中-公开
标题翻译： siRNA靶向二酰基甘油O-酰基转移酶同源物2（DGAT2）
公开(公告)号：US20120270751A1
公开(公告)日：2012-10-25
申请号：US13539630
申请日：2012-07-02
申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
发明人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
IPC分类号： C40B40/06 , C07H21/02
CPC分类号： C12N15/113 , C12N15/111 , C12N15/1135 , C12N2310/11 , C12N2310/14 , C12N2320/11 , G16B20/00
摘要： Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for DGAT2.
摘要翻译：通过使用siRNA技术，有效的序列特异性基因沉默是可能的。通过合理设计选择特定的siRNA，可以最大限度地产生有效的基因沉默试剂，以及沉默基因的方法。公开了通过合理设计siRNA产生的方法，组合物和试剂盒，包括针对DGAT2的核苷酸序列的那些。

9. 发明申请

US20120258889A1 siRNA Targeting Kinase Insert Domain Receptor (KDR) 有权
标题翻译： siRNA靶向激酶插入片段受体（KDR）
公开(公告)号：US20120258889A1
公开(公告)日：2012-10-11
申请号：US13524015
申请日：2012-06-15
申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
发明人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
IPC分类号： C07H21/02 , C40B40/06
CPC分类号： C12N15/113 , C12N15/111 , C12N15/1135 , C12N2310/11 , C12N2310/14 , C12N2320/11 , G06F19/18
摘要： Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for KDR.
摘要翻译：通过使用siRNA技术，有效的序列特异性基因沉默是可能的。通过合理设计选择特定的siRNA，可以最大限度地产生有效的基因沉默试剂，以及沉默基因的方法。公开了通过合理设计siRNA产生的方法，组合物和试剂盒，包括针对KDR的核苷酸序列的那些。

10. 发明授权

US08232385B2 siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) 有权
标题翻译： siRNA靶向细胞周期蛋白依赖性激酶抑制剂1B（p27，Kip1）（CDKN1B）
公开(公告)号：US08232385B2
公开(公告)日：2012-07-31
申请号：US13135443
申请日：2011-07-05
申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
发明人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
IPC分类号： C07H21/04 , C07H21/02 , A61K48/00
CPC分类号： C07H21/02 , A61K31/713 , C07H21/00 , C12N15/111 , C12N15/113 , C12N15/1135 , C12N15/1136 , C12N15/1137 , C12N15/1138 , C12N2310/14 , C12N2320/10 , C12N2320/11 , C12N2330/30 , C12Y304/21047 , G06F19/18
摘要： Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for CDKN1B.
摘要翻译：通过使用siRNA技术，有效的序列特异性基因沉默是可能的。通过合理设计选择特定的siRNA，可以最大限度地产生有效的基因沉默试剂，以及沉默基因的方法。公开了通过合理设计siRNA产生的方法，组合物和试剂盒，包括针对CDKN1B的核苷酸序列的那些。

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