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1. 发明授权

US08362771B2 Establishment of parameters to adjust a magnetic field shim for a magnetic resonance examination of a patient 有权
标题翻译：建立调整磁场垫片的参数，进行磁共振检查
公开(公告)号：US08362771B2
公开(公告)日：2013-01-29
申请号：US12687958
申请日：2010-01-15
申请人： Melanie Dornhaus , Stephan Kannengiesser
发明人： Melanie Dornhaus , Stephan Kannengiesser
IPC分类号： G01V3/00
CPC分类号： G01R33/3875 , G01R33/243 , G01R33/4835 , G01R33/5617 , G01R33/56375 , G01R33/56383
摘要： A fast, efficient, qualitatively high-grade shim is enabled in a magnetic resonance apparatus having a displaceable patient bed and an examination region of the patient that is to be examined is larger than an imaging region of the magnetic resonance apparatus. Field inhomogeneities are measured while the examination region is moved through the imaging region by a continuous displacement of the patient bed with the patient positioned thereon. Information representing field inhomogeneities is acquired at multiple positions of the patient bed from respective magnetic resonance signals received at these positions, by excitation of multiple respective slices before the readout of the echo of the first of these slices, with one echo train composed of multiple echoes being generated per excitation signal. Shim parameters of the magnetic resonance apparatus are adjusted dependent on the measured information.
摘要翻译：在具有可位移的患者床的磁共振装置中能够实现快速，高效，定性高档的垫片，并且待检查的患者的检查区域大于磁共振装置的成像区域。当检测区域通过患者定位在其上的患者床的连续移位而移动通过成像区域时，测量场不均匀性。通过在读出这些切片中的第一个的回波之前激励多个相应的切片，在由多个回波组成的一个回波串的情况下，通过在多个相应切片的激发，从患者床的多个位置获取表示场不均匀性的信息，每个激励信号产生。根据测量信息调整磁共振设备的Shim参数。

2. 发明申请

US20100182007A1 ESTABLISHMENT OF PARAMETERS TO ADJUST A MAGNETIC FIELD SHIM FOR A MAGNETIC RESONANCE EXAMINATION OF A PATIENT 有权
标题翻译：建立用于调整患者的磁共振检查的磁场的参数
公开(公告)号：US20100182007A1
公开(公告)日：2010-07-22
申请号：US12687958
申请日：2010-01-15
申请人： Melanie Dornhaus , Stephan Kannengiesser
发明人： Melanie Dornhaus , Stephan Kannengiesser
IPC分类号： G01R33/48
CPC分类号： G01R33/3875 , G01R33/243 , G01R33/4835 , G01R33/5617 , G01R33/56375 , G01R33/56383
摘要： A fast, efficient, qualitatively high-grade shim is enabled in a magnetic resonance apparatus and a method to set shim parameters of a magnetic resonance apparatus, to prepare the implementation of a magnetic resonance examination of a patient with an imaging medical magnetic resonance apparatus having a displaceable patient bed, wherein an examination region of the patient that is to be examined is larger than an imaging region of the magnetic resonance apparatus.Field inhomogeneities are measured while the examination region is moved through the imaging region by a continuous displacement of the patient bed with the patient positioned thereon. Information representing field inhomogeneities (B0 map) is acquired at multiple positions of the patient bed from respective magnetic resonance signals received at these positions. Information representing field inhomogeneities is acquired by excitation of multiple respective slices before the readout of the echo of the first of these slices, with one echo train composed of multiple echoes being generated per excitation signal.Shim parameters of the magnetic resonance apparatus are adjusted dependent on the measured information.A magnetic resonance examination of the examination region is implemented with the apparatus shimmed according to the shim parameters.
摘要翻译：一种磁共振装置和一种设置磁共振装置的垫片参数的方法能够实现快速，高效，定性高等级的垫片，以准备用具有成像医用磁共振装置的成像医用磁共振装置实施磁共振检查，可移位的患者床，其中待检查的患者的检查区域大于磁共振设备的成像区域。当检测区域通过患者定位在其上的患者床的连续移位而移动通过成像区域时，测量场不均匀性。在患者床的多个位置从在这些位置处接收的各个磁共振信号中获取表示场不均匀性（B0图）的信息。表示场不均匀性的信息通过在读出第一个这些片的回波之前激励多个相应的片，通过每个激励信号产生由多个回波组成的一个回波串来获取。根据测量信息调整磁共振设备的Shim参数。检查区域的磁共振检查是在设备根据垫片参数进行光滑化的情况下进行的。

3. 发明授权

US09194925B2 Fat and iron quantification using a multi-step adaptive fitting approach with multi-echo magnetic resonance imaging 有权
标题翻译：脂肪和铁定量使用多步自适应拟合方法与多回波磁共振成像
公开(公告)号：US09194925B2
公开(公告)日：2015-11-24
申请号：US14054903
申请日：2013-10-16
申请人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser
发明人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser
IPC分类号： G01R33/50 , G01R33/48
CPC分类号： G01R33/4828 , G01R33/50
摘要： A computer-implemented method for quantifying fat and iron in anatomical tissue includes acquiring a plurality of multi-echo signal datasets representative of the anatomical tissue using a magnetic resonance (MR) pulse sequence. A plurality of multi-echo signal datasets are selected from the plurality of multi-echo signal datasets and used to determine a first water magnitude value and a first fat magnitude value. In response to determining that the multi-echo signal datasets include at least three multi-echo datasets, a first stage analysis is performed. This first stage analysis comprises selecting a first effective transverse relaxation rate value. Next, first algorithm inputs comprising the first water magnitude value, the first fat magnitude value, and the first effective transverse relation rate value are created. Then, a non-linear fitting algorithm is performed based on the first algorithm inputs to calculate a second water magnitude value, a second fat magnitude value, and a second effective transverse relaxation rate value. A first proton density fat fraction value is then determined based on the second water magnitude value and the second fat magnitude value.
摘要翻译：用于在解剖组织中量化脂肪和铁的计算机实现的方法包括使用磁共振（MR）脉冲序列获取代表解剖组织的多个多回波信号数据集。从多个多回波信号数据集中选择多个多回波信号数据集，并用于确定第一水量值和第一脂肪量值。响应于确定多回波信号数据集包括至少三个多回波数据集，执行第一阶段分析。该第一阶段分析包括选择第一有效横向松弛率值。接下来，创建包括第一水量值，第一脂肪量值和第一有效横向关系速率值的第一算法输入。然后，基于第一算法输入来执行非线性拟合算法，以计算第二水量值，第二脂肪量值和第二有效横向松弛率值。然后基于第二水量值和第二脂肪量值来确定第一质子密度脂肪分数值。

4. 发明申请

US20140161336A1 Dynamic Adaptation of a Degree of Signal Compression for MRT Image Processing 有权
标题翻译： MRT图像处理信号压缩度的动态适应
公开(公告)号：US20140161336A1
公开(公告)日：2014-06-12
申请号：US14088386
申请日：2013-11-23
申请人： Stephan Biber , Stephan Kannengiesser
发明人： Stephan Biber , Stephan Kannengiesser
IPC分类号： G06T11/00 , G06T7/00
CPC分类号： G01R33/5608 , G01R33/3415 , G01R33/5611
摘要： An apparatus and a method for generating an image from N reception signal data sets of signals received by a plurality of coils of a magnetic resonance tomography appliance from a region of a body to be examined using an image processing computer are provided. The apparatus includes a degree-of-compression determining device. A ratio N/M of the number N of N reception signal data sets generated from the signals received by the plurality of coils to a smaller number M of mode data sets is defined taking account of a plurality of parameters. The plurality of parameters at least also represent system resources of the image processing computer. Using a compression computer, the N reception signal data sets are compressed into M mode data sets. After this, the M mode data sets are used by the image processing computer for generating the image of the region of the body.
摘要翻译：提供了一种用于从使用图像处理计算机的被检体的区域从磁共振断层摄影装置的多个线圈接收的N个接收信号数据组生成图像的装置和方法。该装置包括压缩度确定装置。通过考虑多个参数来定义从多个线圈接收到的信号产生的N个接收信号数据集合的数目N的比N / M到模式数据集的较小数量M. 多个参数至少也表示图像处理计算机的系统资源。使用压缩计算机，N个接收信号数据集被压缩成M个模式数据集。之后，M模式数据集由图像处理计算机用于生成身体区域的图像。

5. 发明授权

US08598873B2 Magnetic resonance method and apparatus for time-resolved acquisition of magnetic resonance data 有权
标题翻译：用于时间分辨采集磁共振数据的磁共振方法和装置
公开(公告)号：US08598873B2
公开(公告)日：2013-12-03
申请号：US12700191
申请日：2010-02-04
申请人： Stephan Kannengiesser , Peter Schmitt , Michael Zenge
发明人： Stephan Kannengiesser , Peter Schmitt , Michael Zenge
IPC分类号： A61B5/055 , G01R33/563 , G01R33/561
CPC分类号： G01R33/56375 , A61B5/0555 , G01R33/5619 , G01R33/56308 , G01R33/56383
摘要： In a method and apparatus for time-resolved acquisition of magnetic resonance (MR) data, an examination subject is continuously moved through the examination region of an MR scanner, and MR signals are acquired. Prior to the acquisition of MR signals, a phase coding that corresponds to a position for data entry in k-space is carried out. An interruption of the movement of the subject takes place at a predetermined table position, and the acquisition of MR signals is continued over the course of a predetermined time period, while the subject is at rest in the predetermined position. At least while the subject is at rest, the phase coding causes acquisition of a predetermined number of MR signals for filling a first region of k-space to alternate with MR data and a predetermined number of MR signals for filling a second region of k-space.
摘要翻译：在用于时间分辨获取磁共振（MR）数据的方法和装置中，检查对象连续移动通过MR扫描器的检查区域，并且获取MR信号。在获取MR信号之前，执行对应于k空间中的数据输入位置的相位编码。被检体的动作的中断发生在规定的工作台位置，并且在预定时间段内持续进行MR信号的采集，同时被检体在预定位置处于静止状态。至少在被摄体处于静止状态时，相位编码使得获得预定数量的MR信号用于填充k空间的第一区域以与MR数据交替并且预定数量的MR信号用于填充k-空间的第二区域，空间。

6. 发明申请

US20070013374A1 Method and apparatus for improved transmission-side accelerated PPA-based volume-selective magnetic resonance imaging 有权
标题翻译：用于改进传输侧加速PPA体积选择性磁共振成像的方法和装置
公开(公告)号：US20070013374A1
公开(公告)日：2007-01-18
申请号：US11408552
申请日：2006-04-21
申请人： Mark Griswold , Stephan Kannengiesser
发明人： Mark Griswold , Stephan Kannengiesser
IPC分类号： G01V3/00 , A61B5/05
CPC分类号： G01R33/5611 , G01R33/5612 , G01R33/583
摘要： In a method for determining transmission coil-specific RF excitation pulses for component coils of a transmission coil array for accelerated, PPA-based volume-selective magnetic resonance excitation of a tissue region of a patient, and a magnetic resonance tomography apparatus operating according to the method, a first series of volume-selective RF excitation pulses along a first transmission trajectory in transmission κ-space is successively individually radiated by the component coils of the transmission coil array and the resulting magnetic resonance signals are received, and a second series of volume-selected RF excitation pulses along a further reduced transmission trajectory in transmission κ-space is simultaneously radiated by all component coils of the transmission coil array and the resulting magnetic resonance signals are received, and a complete transmission trajectory in transmission K-space is then determined from which combination coefficients are calculated, and the coil specific RF excitation pulses are then calculated from the combination coefficients in order to produce a desired excitation profile.
摘要翻译：在用于确定用于加速的基于PPA的体积选择性磁共振激励患者的组织区域的传输线圈阵列的分量线圈的传输线圈特定RF激励脉冲的方法中，以及根据该方法操作的磁共振断层摄影装置方法中，沿传输线圈阵列中的第一传输轨迹的第一系列体积选择性RF激励脉冲被传输线圈阵列的分量线圈连续单独辐射，并且接收所得到的磁共振信号，并且接收第二系列体积通过传输线圈阵列的所有分量线圈同时辐射沿着传输卡巴空间中进一步减小的传输轨迹的选择的RF激励脉冲，并且接收所得到的磁共振信号，然后确定传输K空间中的完整传输轨迹从中计算组合系数，然后从组合系数计算线圈特定的RF激励脉冲，以便产生期望的激励分布。

7. 发明申请

US20050251023A1 Method and MR apparatus for PPA MR imaging with radial data acquisition 有权
标题翻译：用于具有径向数据采集的PPA MR成像的方法和MR装置
公开(公告)号：US20050251023A1
公开(公告)日：2005-11-10
申请号：US11119478
申请日：2005-04-29
申请人： Stephan Kannengiesser , Thomas Mertelmeier , Arnulf Oppelt
发明人： Stephan Kannengiesser , Thomas Mertelmeier , Arnulf Oppelt
IPC分类号： A61B6/00 , G01N23/00 , G01R33/561 , G21K1/12
CPC分类号： G01R33/5611
摘要： In a method and for MR apparatus PPA imaging with radial data acquisition in magnetic resonance tomography, k-space is under-scanned by acquiring a number of projections φ with a coil array of M component coils, a shift operator C(±nΔk) is determined for a projection φi on the basis of measured magnetizations along a projection φi±α0 that encompasses with φi an angle α0, with n=1, 2, . . . , M−1, the shift operator C(±nΔk) is applied to individual points of projection φi in order to obtain calculated projection points, the determination and the application of the shift operator C(±nΔk) are repeated for all projections φ, and an image is reconstructed in the spatial domain on the basis of the projections, which have been completed purely computationally.
摘要翻译：在磁共振断层成像中利用径向数据采集的方法和MR装置PPA成像中，通过用M个分量线圈的线圈阵列获取多个投影phi，使k空间被扫描，移位算子C（±nDeltak）为基于沿着具有角度α0，其中n = 1,2，...包围的投影phi±α0的测量磁化来确定投影phii。。。，M-1，将移位算子C（±nDeltak）应用于投影phii的各个点，以获得计算的投影点，对于所有投影phi重复移位算子C（±nDeltak）的确定和应用，并且基于已经完全在计算上完成的投影，在空间域中重建图像。

8. 发明授权

US09297873B2 Method to select an undersampling scheme for magnetic resonance imaging, and magnetic resonance imaging method and system using such a selected undersampling scheme 有权
标题翻译：选择用于磁共振成像的欠采样方案的方法，以及使用这种选择的欠采样方案的磁共振成像方法和系统
公开(公告)号：US09297873B2
公开(公告)日：2016-03-29
申请号：US13627042
申请日：2012-09-26
申请人： Kai Tobias Block , Stephan Kannengiesser , Marcel Dominik Nickel
发明人： Kai Tobias Block , Stephan Kannengiesser , Marcel Dominik Nickel
IPC分类号： G01R33/561
CPC分类号： G01R33/5611
摘要： In a method to select an undersampling scheme of k-space and an associated set of reconstruction kernels to acquire reduced magnetic resonance (MR) data sets with multiple coils, a calibration data set is acquired for each of the respective coils, a noise covariance is determined from autocorrelations and correlations of the noise of the various coils. At least one set of reconstruction kernels is calculated for each of the multiple undersampling schemes from the calibration data sets of the various coils. For each set of reconstruction kernels, a characteristic value is calculated from the noise covariance and the respective reconstruction kernels of the coils, with the characteristic value being proportional to a spatial mean value of a signal noise of an MR image. A selected undersampling scheme and a selected set of reconstruction kernels are selected based on the calculated characteristic values.
摘要翻译：在选择k空间的欠采样方案和相关联的一组重建内核以获取具有多个线圈的减小的磁共振（MR）数据集的方法中，针对各个线圈获取校准数据集，噪声协方差为根据各种线圈的噪声的自相关性和相关性确定。根据各种线圈的校准数据集，对于多个欠采样方案中的每一个计算至少一组重构内核。对于每组重建内核，根据噪声协方差和线圈的相应重建内核计算特征值，其特征值与MR图像的信号噪声的空间平均值成比例。基于所计算的特征值来选择所选的欠采样方案和所选择的重构内核集合。

9. 发明申请

US20140126795A1 FAT AND IRON QUANTIFICATION USING A MULTI-STEP ADAPTIVE FITTING APPROACH WITH MULTI-ECHO MAGNETIC RESONANCE IMAGING 有权
标题翻译：使用多步自适应拟合方法与多重磁共振成像的脂肪和铁定量
公开(公告)号：US20140126795A1
公开(公告)日：2014-05-08
申请号：US14054903
申请日：2013-10-16
申请人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser
发明人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser
IPC分类号： G01R33/48 , G06T7/00
CPC分类号： G01R33/4828 , G01R33/50
摘要： A computer-implemented method for quantifying fat and iron in anatomical tissue includes acquiring a plurality of multi-echo signal datasets representative of the anatomical tissue using a magnetic resonance (MR) pulse sequence. A plurality of multi-echo signal datasets are selected from the plurality of multi-echo signal datasets and used to determine a first water magnitude value and a first fat magnitude value. In response to determining that the multi-echo signal datasets include at least three multi-echo datasets, a first stage analysis is performed. This first stage analysis comprises selecting a first effective transverse relaxation rate value. Next, first algorithm inputs comprising the first water magnitude value, the first fat magnitude value, and the first effective transverse relation rate value are created. Then, a non-linear fitting algorithm is performed based on the first algorithm inputs to calculate a second water magnitude value, a second fat magnitude value, and a second effective transverse relaxation rate value. A first proton density fat fraction value is then determined based on the second water magnitude value and the second fat magnitude value.
摘要翻译：用于在解剖组织中量化脂肪和铁的计算机实现的方法包括使用磁共振（MR）脉冲序列获取代表解剖组织的多个多回波信号数据集。从多个多回波信号数据集中选择多个多回波信号数据集，并用于确定第一水量值和第一脂肪量值。响应于确定多回波信号数据集包括至少三个多回波数据集，执行第一阶段分析。该第一阶段分析包括选择第一有效横向松弛率值。接下来，创建包括第一水量值，第一脂肪量值和第一有效横向关系速率值的第一算法输入。然后，基于第一算法输入来执行非线性拟合算法，以计算第二水量值，第二脂肪量值和第二有效横向松弛率值。然后基于第二水量值和第二脂肪量值来确定第一质子密度脂肪分数值。

10. 发明申请

US20140125336A1 Adaptive and Interactive Assessment of Tissue Properties in MR Imaging 有权
标题翻译： MR成像中组织性质的自适应和互动评估
公开(公告)号：US20140125336A1
公开(公告)日：2014-05-08
申请号：US14054914
申请日：2013-10-16
申请人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser
发明人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser
IPC分类号： G01R33/48 , G01R33/50
CPC分类号： G01R33/4828 , G01R33/50
摘要： Embodiments relate to evaluating properties of tissues with magnetic resonance imaging (MRI). A MR image is used to measure a characteristic that influences a particular chemical property of a tissue. In an exemplary embodiment, tissue transverse relaxation values or relaxation rates, which can readily be measured from MR images, are used to evaluate iron deposition in tissue. Iron deposition influences the tissue transverse relaxation values (T2 or T2*) or relaxation rates (R2=1/T2 or R2*=1/T2*). A clinically relevant R2CR* map is calculated based on the known values of the effective R2eff*, the water R2w*, and the fat R2f* by incorporating the most relevant value for each individual image element of a plurality of image elements of an MR image of the tissue. The clinically relevant R2CR* map provides an accurate evaluation of iron deposition in any region of the tissue with the use of one map.
摘要翻译：实施例涉及评估具有磁共振成像（MRI）的组织的性质。 MR图像用于测量影响组织的特定化学性质的特征。在示例性实施例中，可以容易地从MR图像测量的组织横向松弛值或松弛率用于评估组织中的铁沉积。铁沉积影响组织横向弛豫值（T2或T2 *）或松弛率（R2 = 1 / T2或R2 * = 1 / T2 *）。基于有效R2eff *，水R2w *和脂肪R2f *的已知值，通过对MR图像的多个图像元素的每个单独图像元素合并最相关值来计算临床相关的R2CR *图的组织。临床上相关的R2CR *图谱使用一张地图提供组织任何区域铁沉积的准确评估。

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