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    • 1. 发明授权
    • Ordering projections for magnetic resonance
    • 磁共振的订购预测
    • US09086466B2
    • 2015-07-21
    • US13446361
    • 2012-04-13
    • Mark GriswoldGregory R. Lee
    • Mark GriswoldGregory R. Lee
    • G01R33/48G01R33/563
    • G01R33/4826G01R33/563
    • Example apparatus and methods order projections in a 3D MRI acquisition to achieve improved equidistant spacing or to achieve improved adherence to a target distribution. The equidistant or target spacing may exist in k-space and/or in kt-space. In one embodiment, the improved equidistant spacing is a substantially uniform spacing. The substantially uniform spacing may be achieved using a modification of a charge repulsion analysis that treats points of projections that intersect the surface of a 3D volume to be imaged as point charges distributed on the 3D volume. In another embodiment, the target spacing may be uniform, non-uniform, uniform in parts and non-uniform in other parts, and other combinations.
    • 示例性装置和方法在3D MRI采集中排序投影以实现改进的等距间距或实现改善对目标分布的依从性。 等距或目标间距可存在于k空间和/或kt空间中。 在一个实施例中,改进的等距间距是基本均匀的间距。 可以使用电荷排斥分析的修改来实现基本上均匀的间隔,所述电荷排斥分析将待映射的3D体积的表面相交的投影点作为分布在3D体积上的点电荷进行处理。 在另一个实施例中,目标间隔可以是均匀的,不均匀的,部分均匀的,在其他部分中不均匀,以及其它组合。
    • 4. 发明申请
    • Method for MRT imaging on the basis of conventional PPA reconstruction methods
    • 基于常规PPA重建方法的MRT成像方法
    • US20060284812A1
    • 2006-12-21
    • US11409373
    • 2006-04-21
    • Mark GriswoldVladimir JellusStephan Kannengiesser
    • Mark GriswoldVladimir JellusStephan Kannengiesser
    • G09G3/36
    • G01R33/5611
    • In a method and apparatus for generating a magnetic resonance image of a contiguous region of a human body on the basis of partial parallel acquisition (PPA) by excitation of nuclear spins and measurement of radio-frequency signals indicating the excited spins, the spin excitation is implemented in steps with measurement of an RF response signal simultaneously in each of a number of N component coils. a number of response signals thus are acquired that, for each component coil, form an incomplete data set (40) of acquired RF signals. Additional acquired calibration data points exist for each incomplete data set. The N incomplete data sets are acquired to a subset of M reduced, incomplete data sets on the basis of an N×M reduction matrix, so that M reduced, incomplete data sets are obtained, M complete data sets are formed on the basis of an N×M reconstruction matrix with the non-measured lines of the M reduced, incomplete data sets being reconstructed from all N incomplete data sets. A spatial transformation of the completed reduced data sets is then implemented in order to form a complete image data set from each completed, reduced data set.
    • 在通过激励核自旋的部分并行采集(PPA)和表示激发的自旋的射频信号的测量来产生人体的连续区域的磁共振图像的方法和装置中,自旋激发是 在多个N个分量线圈的每一个中同时测量RF响应信号的步骤实现。 因此,对于每个分量线圈,获得多个响应信号,形成所获取的RF信号的不完整数据集(40)。 对于每个不完整的数据集,存在额外的获取的校准数据点。 N个不完整的数据集基于N×M个缩减矩阵被获取到M个不完整的数据集的子集,从而获得M个减少的不完整的数据集,M个完整数据集是基于N×M重建形成的 矩阵,其中M个未测量的线减少,不完整的数据集从所有N个不完整的数据集重建。 然后实现完成的缩减数据集的空间变换,以便从每个完成的简化数据集合形成完整的图像数据集。
    • 5. 发明授权
    • Magnetic resonance imaging method and apparatus employing partial parallel acquisition, wherein each coil produces a complete k-space datasheet
    • 使用部分并行采集的磁共振成像方法和装置,其中每个线圈产生完整的k空间数据表
    • US06841998B1
    • 2005-01-11
    • US10117396
    • 2002-04-05
    • Mark Griswold
    • Mark Griswold
    • G01R33/561G01V3/00
    • G01R33/5611
    • In a method and apparatus for magnetic resonance imaging of an interconnected region of a human body on the basis of a partially parallel acquisition (PPA) by excitation of nuclear spins and measurement of the radio-frequency signals produced by the excited nuclear spins, a number of spin excitations and measurements of an RF response signal are implemented simultaneously in every component coil of a number of RF reception coils. As a result a number of response signals are acquired that form a reduced dataset of received RF signals for each component coil. Additional calibration data points are acquired for each reduced dataset. A complete image dataset is formed for each component coil on the basis of the reduced dataset for that component coil and at least one further, reduced dataset of a different component coil. A spatial transformation of the image dataset of each component coil is implemented in order to form a complete image of each component coil.
    • 在通过激励核自旋的部分并行采集(PPA)和由激励的核自旋产生的射频信号的测量的人体的互连区域的磁共振成像的方法和装置中, 的自旋激励和RF响应信号的测量在多个RF接收线圈的每个分量线圈中同时实现。 结果,获得了多个响应信号,其形成每个分量线圈的接收的RF信号的减少的数据集。 为每个缩减的数据集获取额外的校准数据点。 基于用于该组件线圈的减少的数据集和不同组件线圈的至少一个另外的减少的数据集,为每个分量线圈形成完整的图像数据集。 实现每个分量线圈的图像数据集的空间变换,以形成每个分量线圈的完整图像。
    • 6. 发明授权
    • Coil array autocalibration MR imaging
    • US06289232B1
    • 2001-09-11
    • US09050404
    • 1998-03-30
    • Peter M. JakobDaniel K. SodicksonMark Griswold
    • Peter M. JakobDaniel K. SodicksonMark Griswold
    • A61B5055
    • G01R33/5611
    • A magnetic resonance (MR) imaging apparatus and technique exploits spatial information inherent in a surface coil array to increase MR image acquisition speed, resolution and/or field of view. Magnetic resonance response signals are acquired simultaneously in the component coils of the array and, using an autocalibration procedure, are formed into two or more signals to fill a corresponding number of lines in the signal measurement data matrix. In a Fourier embodiment, lines of the k-space matrix required for image production are formed using a set of separate, preferably linear combinations of the component coil signals to substitute for spatial modulations normally produced by phase encoding gradients. One or a few additional gradients are applied to acquire autocalibration (ACS) signals extending elsewhere in the data space, and the measured signals are fitted to the ACS signals to develop weights or coefficients for filling additional lines of the matrix from each measurement set. The ACS lines may be taken offset from or in a different orientation than the measured signals, for example, between or across the measured lines. Furthermore, they may be acquired at different positions in k-space, may be performed at times before, during or after the principal imaging sequence, and may be selectively acquired to optimized the fitting for a particular tissue region or feature size. The in vivo fitting procedure is readily automated or implemented in hardware, and produces an enhancement of image speed and/or quality even in highly heterogeneous tissue. A dedicated coil assembly automatically performs the calibration procedure and applies it to measured lines to produce multiple correctly spaced output signals. One application of the internal calibration technique to a subencoding imaging process applies the ACS in the central region of a sparse set of measured signals to quickly form a full FOV low resolution image. The full FOV image is then used to determine coil sensitivity related information and dealias folded images produced from the sparse set.
    • 9. 发明申请
    • Nuclear Magnetic Resonance (NMR) Fingerprinting
    • 核磁共振(NMR)指纹图谱
    • US20130265047A1
    • 2013-10-10
    • US13623104
    • 2012-09-19
    • Mark GriswoldNicole SieberlichVikas GulaniDan Ma
    • Mark GriswoldNicole SieberlichVikas GulaniDan Ma
    • G01R33/56
    • G01R33/56G01R33/4828G01R33/50G01R33/56341
    • Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic configured to repetitively and variably sample a (k, t, E) space associated with an object to acquire a set of NMR signals. Members of the set of NMR signals are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The varying parameters may include flip angle, echo time, RF amplitude, and other parameters. The NMR apparatus may also include a signal logic configured to produce an NMR signal evolution from the NMR signals, and a characterization logic configured to characterize a resonant species in the object as a result of comparing acquired signals to reference signals.
    • 描述了与NMR指纹图谱相关联的装置,方法和其它实施例。 一个示例NMR装置包括NMR逻辑,其被配置为重复地且可变地采样与物体相关联的(k,t,E)空间,以获得一组NMR信号。 一组NMR信号的成员与(k,t,E)空间中的不同点相关联。 t和/或E以非常数方式变化进行采样。 变化的参数可以包括翻转角,回波时间,RF幅度和其他参数。 NMR装置还可以包括被配置为从NMR信号产生NMR信号演化的信号逻辑,以及被配置为通过将获取的信号与参考信号进行比较的结果来表征对象中的共振物种的表征逻辑。
    • 10. 发明申请
    • RELAXOMETRY
    • 放大镜
    • US20120262165A1
    • 2012-10-18
    • US13085690
    • 2011-04-13
    • Mark GRISWOLDNicole SeiberlichDan Ma
    • Mark GRISWOLDNicole SeiberlichDan Ma
    • G01R33/48
    • G01R33/50G01R33/5611G01R33/5614
    • Apparatus, methods, and other embodiments associated with multi-scale orthogonal matching pursuit (OMP) for magnetic resonance imaging (MRI) relaxometry are described. One example method includes controlling a nuclear magnetic resonance (NMR) apparatus to cause selected nuclei in an item to resonate by applying radio frequency (RF) energy to the item and then acquiring multiple series of magnetic resonance (MR) images of the item, the series of MR images having different scales. The example method includes controlling the NMR apparatus to produce a combined signal evolution from a first signal evolution associated with a first series of MR images and a second signal evolution associated with a second series of MR images and to characterize relaxation of the selected nuclei in the item as a function of an OMP that compares the combined signal evolution to a set of combined comparative signal evolutions.
    • 描述了与用于磁共振成像(MRI)松弛度测量的多尺度正交匹配追踪(OMP)相关联的装置,方法和其它实施例。 一个示例性方法包括通过对物品施加射频(RF)能量,然后获取物品的多个系列的磁共振(MR)图像来控制核磁共振(NMR)装置来引起物品中的选定的核共振, 具有不同尺度的一系列MR图像。 该示例性方法包括控制NMR装置以从与第一系列MR图像相关联的第一信号演变和与第二系列MR图像相关联的第二信号演变产生组合信号演变,并且表征所选择的核的松弛 作为OMP的函数的项目,其将组合信号演进与一组组合的比较信号演变进行比较。