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1. 发明公开

US20240058125A1 TRANSCATHETER DELIVERY SYSTEM AND METHOD WITH CONTROLLED EXPANSION AND CONTRACTION OF PROSTHETIC HEART VALVE 审中-公开
公开(公告)号：US20240058125A1
公开(公告)日：2024-02-22
申请号：US18385338
申请日：2023-10-30
申请人： Medtronic, Inc.
发明人： Matthew Rust , Padraig Savage , Gianfranco Pellegrini , Finn Rinne
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/2439 , A61F2002/9505
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.

2. 发明申请

US20140277419A1 Anti-Paravalvular Leakage Component for a Transcatheter Valve Prosthesis 有权
标题翻译：用于经导管瓣假体的抗瓣膜渗漏组件
公开(公告)号：US20140277419A1
公开(公告)日：2014-09-18
申请号：US13795066
申请日：2013-03-12
申请人： MEDTRONIC, INC.
发明人： Kshitija Garde , Philip Haarstad , Igor Kovalsky , Stephen Nash , Michael Krivoruchko , Gianfranco Pellegrini , Finn Rinne , Matthew Rust , Jeffrey Sandstrom , Padraig Savage , Adam Shipley , William Steinberg
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2403 , A61F2/2412 , A61F2/2418 , A61F2250/0069
摘要： A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.
摘要翻译：经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。在压缩构型中，每个支柱远离支架远端延伸。在展开的构造中，每个支柱向近端延伸远离支架的远端。在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

3. 发明授权

US09649191B2 Stents for prosthetic heart valves 有权
公开(公告)号：US09649191B2
公开(公告)日：2017-05-16
申请号：US14100984
申请日：2013-12-09
申请人： Medtronic, Inc.
发明人： Padraig Savage , Gianfranco Pellegrini , Finn Rinne , Matthew Rust , Michael Krivoruchko
IPC分类号： A61F2/24 , A61F2/848
CPC分类号： A61F2/24 , A61F2/2418 , A61F2/848 , A61F2002/8483 , A61F2220/0016 , A61F2230/0054 , A61F2230/008
摘要： A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

4. 发明申请

US20210077256A1 STENTS FOR PROSTHETIC HEART VALVES 有权
公开(公告)号：US20210077256A1
公开(公告)日：2021-03-18
申请号：US17086511
申请日：2020-11-02
申请人： Medtronic, Inc.
发明人： Gianfranco M. Pellegrini , Mike Krivoruchko , Finn Rinne , Matthew Rust
IPC分类号： A61F2/24
摘要： A prosthetic valve including a wire frame having a generally tubular body portion, an interior area, a longitudinal axis, a first end comprising a plurality of crowns, and a second end comprising a greater number of crowns than the first end. The wire frame includes a plurality of adjacent rows of modified diamond-shaped structures extending between the first and second ends. The prosthetic valve further includes a valve structure that includes a plurality of leaflets and that is attached within the interior area of the wire frame.

5. 发明申请

US20170100246A1 TRANSCATHETER DELIVERY SYSTEM AND METHOD WITH CONTROLLED EXPANSION AND CONTRACTION OF PROSTHETIC HEART VALVE 审中-公开
公开(公告)号：US20170100246A1
公开(公告)日：2017-04-13
申请号：US15387071
申请日：2016-12-21
申请人： Medtronic, Inc.
发明人： Matthew Rust , Savage Padraig , Gianfranco Pellegrini , Finn Rinne
IPC分类号： A61F2/24
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.

6. 发明授权

US11020223B2 Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve 有权
公开(公告)号：US11020223B2
公开(公告)日：2021-06-01
申请号：US15387071
申请日：2016-12-21
申请人： Medtronic, Inc.
发明人： Matthew Rust , Savage Padraig , Gianfranco Pellegrini , Finn Rinne
IPC分类号： A61F2/24 , A61F2/95 , A61F2/966
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.

7. 发明授权

US10231832B2 Stents for prosthetic heart valves 有权
公开(公告)号：US10231832B2
公开(公告)日：2019-03-19
申请号：US15482032
申请日：2017-04-07
申请人： Medtronic, Inc.
发明人： Padraig Savage , Gianfranco Pellegrini , Finn Rinne , Matthew Rust , Michael Krivoruchko
IPC分类号： A61F2/24
摘要： A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

8. 发明授权

US08986375B2 Anti-paravalvular leakage component for a transcatheter valve prosthesis 有权
标题翻译：用于经导管瓣膜假体的抗瓣膜泄漏组件
公开(公告)号：US08986375B2
公开(公告)日：2015-03-24
申请号：US13795066
申请日：2013-03-12
申请人： Medtronic, Inc.
发明人： Kshitija Garde , Philip Haarstad , Igor Kovalsky , Stephen Nash , Gianfranco Pellegrini , Finn Rinne , Matthew Rust , Jeffrey Sandstrom , Padraig Savage , William Steinberg
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2403 , A61F2/2412 , A61F2/2418 , A61F2250/0069
摘要： A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.
摘要翻译：经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。在压缩构型中，每个支柱远离支架远端延伸。在展开的构造中，每个支柱向近端延伸远离支架的远端。在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

9. 发明申请

US20140142693A1 Valve Prosthesis Frames 审中-公开
标题翻译：瓣膜假体框架
公开(公告)号：US20140142693A1
公开(公告)日：2014-05-22
申请号：US13681594
申请日：2012-11-20
申请人： MEDTRONIC, INC
发明人： Michael Krivoruchko , Karan Punga , Finn Rinne
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2220/005 , A61F2230/0013 , A61F2230/008 , A61F2250/0036
摘要： A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.
摘要翻译：假体可以包括可折叠的可再膨胀框架，其包括限定第一排和第二排可膨胀单元的第一组，第二组和第三组支柱。在一些实施例中，第一，第二和第三组支柱的支柱可以是锥形的。在一些实施例中，框架可以包括中间部分和靠近中间部分的流入部分。流入部分可以包括与中间部分相邻的凹形鞍形部分和向外张开的部分。

10. 发明授权

US11833045B2 Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve 有权
公开(公告)号：US11833045B2
公开(公告)日：2023-12-05
申请号：US17327981
申请日：2021-05-24
申请人： Medtronic, Inc.
发明人： Matthew Rust , Padraig Savage , Gianfranco Pellegrini , Finn Rinne
IPC分类号： A61F2/24 , A61F2/95 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/2439 , A61F2002/9505 , A61F2002/9665 , A61F2230/008 , A61F2230/0054
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.

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