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1. 发明申请

US20110201608A1 SUBSTITUTED NAPHTHYRIDINES AND USE THEREOF AS MEDICINES 审中-公开
标题翻译：取代的萘啶酮及其作为药物的用途
公开(公告)号：US20110201608A1
公开(公告)日：2011-08-18
申请号：US13057288
申请日：2009-07-23
申请人： Matthias Hoffmann , Thierry Bouyssou , Georg Dahamnn , Harald Engelhardt , Dennis Fiegen , Sandra Handschum , Silke Hobbie , Takeshi Kono , Ulrich Reiser , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
发明人： Matthias Hoffmann , Thierry Bouyssou , Georg Dahamnn , Harald Engelhardt , Dennis Fiegen , Sandra Handschum , Silke Hobbie , Takeshi Kono , Ulrich Reiser , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
IPC分类号： A61K31/5377 , C07D471/04 , A61K31/496 , A61P11/06 , A61P19/02 , A61P1/04 , A61P17/06 , A61P35/00 , A61P17/00 , A61P11/00
CPC分类号： C07D471/04 , C07D487/04 , C07D487/10 , C07D513/04
摘要： The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 denotes a group A selected from among —O—R3, —NR3R4, —CR3R4R5, -(ethyne)-R3, —S—R3, —SO—R3 and SO2—R3 or R1 denotes a group B selected from among C6-10-aryl, five- to ten-membered, mono- or bicyclic heteroaryl with 1-3 heteroatoms selected independently of one another from among N, O and S; while this heteroaryl is linked to the structure according to formula 1 via either a C atom or an N atom, three- to ten-membered, mono- or bicyclic, saturated or partially saturated heterocyclic group with 1-3 heteroatoms selected independently of one another from among N, O and S, while this heterocyclic group is linked to the structure according to formula 1 via either a C atom or an N atom, and 5- to 11-membered spiro group which may optionally contain 1, 2 or 3 heteroatoms selected independently of one another from among N, O and S, while this spiro group is linked to the structure according to formula 1 via either a C atom or an N atom, while this group B may optionally be substituted as described in claim 1 and wherein R2 is and R3, R4, R5, R6, R6′, R7, R8, R9, R10, V, n and m may have the meanings given in claim 1, as well as pharmaceutical compositions containing these compounds.
摘要翻译：本发明涉及式1的新取代的萘啶，以及其药学上可接受的盐，非对映异构体，对映异构体，外消旋体，水合物或溶剂化物，其中R1表示选自-O-R3，-NR3R4，-CR3R4R5，（乙炔）-R 3，-S-R 3，-SO-R 3和SO 2 -R 3或R 1表示选自C 6-10 - 芳基，5至10元，单 - 或双环杂芳基和1-3 从N，O和S中彼此独立地选择的杂原子; 而该杂芳基通过C原子或N原子连接到根据式1的结构，具有1-3个互相独立选择的杂原子的三至十元，单环或二环，饱和或部分饱和的杂环基 N，O和S中的至少一个，而该杂环基通过C原子或N原子与根据式1的结构连接，并且可以任选地含有1,2或3个杂原子的5至11元螺环 N，O和S彼此独立地选择，而该螺环通过C原子或N原子连接到根据式1的结构，而该基团B可以任选地被如权利要求1和其中R2是和R3，R4，R5，R6，R6'，R7，R8，R9，R10，V，n和m可以具有权利要求1中给出的含义，以及含有这些化合物的药物组合物。

2. 发明申请

US20110263549A1 4-DIMETHYLAMINO-PHENYL-SUBSTITUTED NAPHTHYRIDINES, AND USE THEREOF AS MEDICAMENTS 有权
标题翻译： 4-二甲基苯胺基 - 取代的萘啶，并作为药物使用
公开(公告)号：US20110263549A1
公开(公告)日：2011-10-27
申请号：US13057330
申请日：2009-07-23
申请人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
发明人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
IPC分类号： A61K31/573 , A61K31/4375 , A61P11/00 , A61P19/10 , A61P1/04 , A61P31/14 , A61P7/06 , A61P25/00 , C07D471/04 , A61P19/02
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to novel substituted naphthyridines of formula 1 as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates, or solvates thereof. In formula 1, R1 can represent a group A selected from among the group comprising —O—R3, —NR3 R4, —CR3R4R5, -(ethyne)-R3, —S—R3, —SO—R3, and SO2—R3, or R1 represents a group B selected from among the group comprising: —C6-10-aryl;—a five-membered to ten-membered, monocyclic or bicyclic heteroaryl containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heteroaryl is linked to the structure according to formula 1 via a C atom or an N atom;—a three-membered to ten-membered, monocyclic or bicyclic, saturated or partially saturated heterocycle containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heterocycle is linked to the structure according to formula 1 via a C atom or an N atom; and—a 5-membered to 11-membered spiro group which can optionally contain 1, 2, or 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said spiro group is linked to the structure according to formula 1 via a C atom or an N atom, wherein said group B can be optionally substituted as described in claims 1, and R3,R4,R5,R6, and m can have the meanings indicated in claim 1. The invention also relates to pharmaceutical compositions containing said compounds.
摘要翻译：本发明涉及式1的新型取代萘啶以及其药理学上可接受的盐，非对映异构体，对映异构体，外消旋物，水合物或溶剂合物。在式1中，R 1可以表示选自-O-R 3，-NR 3 R 4，-CR 3 R 4 R 5， - （乙炔）-R 3，-S-R 3，-SO-R 3和SO 2 -R 3的基团A，或R 1表示选自包括以下基团的基团：-C 6-10 - 芳基; - 含有1至3个独立地选自以下的杂原子的五元至十元单环或双环杂芳基：N，O，和S，其中所述杂芳基通过C原子或N原子连接到根据式1的结构; - 含有1至3个独立选择的杂原子的三元至十元单环或双环饱和或部分饱和的杂环包括N，O和S的基团，其中所述杂环通过C原子或N原子连接到根据式1的结构; 和可以任选地含有1,2或3个独立地选自包括N，O和S的基团的杂原子的5元至11元螺环，其中所述螺环与根据式1的结构连接通过C原子或N原子，其中所述基团B可以如权利要求1所述任选被取代，并且R 3，R 4，R 5，R 6和m可以具有权利要求1中所示的含义。本发明还涉及药物组合物含有所述化合物。

3. 发明授权

US08957088B2 4-dimethylamino-phenyl-substituted naphthyridines, and use thereof as medicaments 有权
标题翻译： 4-二甲基氨基 - 苯基取代的萘啶，及其用作药物
公开(公告)号：US08957088B2
公开(公告)日：2015-02-17
申请号：US14071016
申请日：2013-11-04
申请人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
发明人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
IPC分类号： A61K31/4375 , C07D471/04 , C07D519/00
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 and R6 may have the meanings as described in claim 1, as well as medicaments which contain these compounds. Further, the invention relates to methods of treating a disease selected from asthma, COPD, allergic rhinitis, adult respiratory distress syndrome, bronchitis, allergic dermatitis, contact dermatitis, idiopathic thrombocytopenic purpura, rheumatoid arthritis and allergic rhinoconjunctivitis by administrating an appropriate amount of a compound of formula 1 to a patient in need thereof.
摘要翻译：本发明涉及式1的新的取代的萘啶，以及其药学上可接受的盐，非对映异构体，对映异构体，外消旋体，水合物或溶剂合物，其中R 1和R 6可以具有权利要求1所述的含义，以及含有这些化合物。此外，本发明涉及通过施用适量的化合物治疗选自哮喘，COPD，变应性鼻炎，成人呼吸窘迫综合征，支气管炎，过敏性皮炎，接触性皮炎，特发性血小板减少性紫癜，类风湿性关节炎和过敏性鼻炎的疾病的方法式1给有需要的患者。

4. 发明授权

US08604049B2 4-dimethylamino-phenyl-substituted naphthyridines, and use thereof as medicaments 有权
标题翻译： 4-二甲基氨基 - 苯基取代的萘啶，及其用作药物
公开(公告)号：US08604049B2
公开(公告)日：2013-12-10
申请号：US13057330
申请日：2009-07-23
申请人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
发明人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
IPC分类号： A61K31/573 , A61K31/4375 , A61P11/00 , A61P19/10 , A61P1/04 , A61P31/14 , A61P7/06 , A61P25/00 , A61P19/02 , C07D471/04
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to novel substituted naphthyridines of formula 1 as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates, or solvates thereof. In formula 1, R1 can represent a group A selected from among the group comprising —O—R3, —NR3R4, —CR3R4R5, -(ethyne)-R3, —S—R3, —SO—R3, and SO2—R3, or R1 represents a group B selected from among the group comprising: —C6-10-aryl; —a five-membered to ten-membered, monocyclic or bicyclic heteroaryl containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heteroaryl is linked to the structure according to formula 1 via a C atom or an N atom; —a three-membered to ten-membered, monocyclic or bicyclic, saturated or partially saturated heterocycle containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heterocycle is linked to the structure according to formula 1 via a C atom or an N atom; and —a 5-membered to 11-membered spiro group which can optionally contain 1, 2, or 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said spiro group is linked to the structure according to formula 1 via a C atom or an N atom, wherein said group B can be optionally substituted as described in claims 1, and R3, R4, R5, R6, and m can have the meanings indicated in claim 1. The invention also relates to pharmaceutical compositions containing said compounds.
摘要翻译：本发明涉及式1的新型取代萘啶以及其药理学上可接受的盐，非对映异构体，对映异构体，外消旋物，水合物或溶剂合物。在式1中，R 1可以表示选自-O-R 3，-NR 3 R 4，-CR 3 R 4 R 5， - （乙炔）-R 3，-S-R 3，-SO-R 3和SO 2 -R 3的基团A，或 R 1表示选自以下的基团B：-C 6-10 - 芳基; 包含1至3个独立地选自N，O和S的杂原子的五元至十元单环或二环杂芳基，其中所述杂芳基通过C原子连接至根据式1的结构，或一个N原子; 包含1-3个独立地选自包括N，O和S的杂原子的3至10元，单环或双环饱和或部分饱和的杂环，其中所述杂环与根据式1的结构连接通过C原子或N原子; 和可以任选地含有1,2或3个独立地选自N，O和S的组的杂原子的5元至11元螺环，其中所述螺环与根据式1的结构连接通过C原子或N原子，其中所述基团B可以如权利要求1所述任选被取代，并且R 3，R 4，R 5，R 6和m可以具有权利要求1中所示的含义。本发明还涉及药物组合物含有所述化合物。

5. 发明授权

US08935554B2 Hand held electronic device with user controlled power saving feature 有权
标题翻译：手持电子设备，具有用户控制的省电功能
公开(公告)号：US08935554B2
公开(公告)日：2015-01-13
申请号：US13394592
申请日：2010-08-25
申请人： Kazuhiro Yanase , Takeshi Kono , Motoki Kobayashi
发明人： Kazuhiro Yanase , Takeshi Kono , Motoki Kobayashi
IPC分类号： G06F1/00 , G06F1/16 , G06F1/32
CPC分类号： G06F1/1677 , A63F2300/1043 , A63F2300/204 , A63F2300/636 , G06F1/1624 , G06F1/3203 , H04M1/0235 , H04M1/0245 , H04M1/236 , H04M1/67 , H04W52/0254 , Y02D70/00
摘要： An opening/closing detection unit detects a transition of an electronic device from an open state to a closed state or from the closed state to the open state. An electrical-power control unit sets an operation mode of an application processing unit that executes an application. When a transition from the open state to the closed state is detected while a hold switch is in an OFF state, the electrical-power control unit switches an operation mode of an application processing unit from a normal mode to a sleep mode. On the other hand, when a transition from the open state to the closed state is detected while the hold switch is in an ON state, the electrical-power control unit does not switch the operation mode of the application processing unit from the normal mode to the sleep mode.
摘要翻译：打开/关闭检测单元检测电子设备从打开状态到关闭状态或从关闭状态到打开状态的转变。电力控制单元设置执行应用的应用处理单元的操作模式。当保持开关处于OFF状态时，当检测到从打开状态到关闭状态的转变时，电力控制单元将应用处理单元的操作模式从正常模式切换到睡眠模式。另一方面，当保持开关处于接通状态时，当检测到从打开状态到关闭状态的转变时，电力控制单元不将应用处理单元的操作模式从正常模式切换到睡眠模式。

6. 发明申请

US20110213986A1 Method for Activating Content and Content Reproduction Apparatus 审中-公开
标题翻译：激活内容和内容再现设备的方法
公开(公告)号：US20110213986A1
公开(公告)日：2011-09-01
申请号：US13000548
申请日：2010-04-20
申请人： Kazuhiro Kanee , Muneki Shimada , Takeshi Kono , Takao Tenma , Shinji Noda
发明人： Kazuhiro Kanee , Muneki Shimada , Takeshi Kono , Takao Tenma , Shinji Noda
IPC分类号： G06F21/22
CPC分类号： G06F9/44589 , G06F21/10 , G06F21/14 , G06F21/51 , G06F21/572 , G06F2221/2109
摘要： A firmware verification section verifies whether a firmware for controlling the activating of contents has been falsified or not, prior to the activating of the contents; a decoding key setting section sets a key to the firmware; the key is used to decode an encrypted activation program for activating the contents, when the firmware has not been falsified; and an activation program decoding section decodes the encrypted activation program by using the firmware with the key set to the firmware.
摘要翻译：在激活内容之前，固件验证部分验证用于控制内容激活的固件是否已被伪造; 解码密钥设置部分将密钥设置为固件; 当固件未被伪造时，该密钥用于解码用于激活内容的加密激活程序; 并且激活程序解码部分通过使用设置有固件的密钥的固件解码加密的激活程序。

7. 发明授权

US06824258B2 Liquid container, liquid supply system and ink jet recording apparatus utilizing the same, and method of mounting liquid container on recording apparatus 有权
标题翻译：液体容器，液体供应系统和使用该液体容器的喷墨记录装置，以及将液体容器安装在记录装置上的方法
公开(公告)号：US06824258B2
公开(公告)日：2004-11-30
申请号：US10067358
申请日：2002-02-07
申请人： Hajime Yamamoto , Eiichiro Shimizu , Takeshi Kono , Masaya Uetsuki , Nobuyuki Hatasa , Hiroshi Koshikawa , Tatsuo Nanjo
发明人： Hajime Yamamoto , Eiichiro Shimizu , Takeshi Kono , Masaya Uetsuki , Nobuyuki Hatasa , Hiroshi Koshikawa , Tatsuo Nanjo
IPC分类号： B41J2175
CPC分类号： B41J2/17553 , B41J2/17513 , B41J2/17523 , B41J2/17546
摘要： A liquid container which supplies ink to its exterior until the ink is almost depleted and allows simple detection of the remaining ink amount, is constructed to distribute components of the ink even after a prolonged standing. The liquid container is provided with a connecting portion for connection to an ink deriving tube and an air introduction tube of an ink jet printer. Both the ink deriving tube and the air introduction tube are positioned for connection to the connecting portion at a position deviated from a center of the bottom of the liquid container. The deviation facilitates mixing of ink components as ink is supplied from the container.
摘要翻译：即使在长时间站立之后，也可以构成向其外部供墨，直到油墨几乎耗尽并容易简单地检测剩余油墨量的液体容器。液体容器设置有用于连接到墨水导出管和喷墨打印机的空气引入管的连接部分。导墨管和空气导入管都位于与液体容器的底部中心偏离的位置处连接到连接部分。当墨水从容器供应时，该偏差便于油墨组分的混合。

8. 发明授权

US08647815B1 Method of manufacturing copper electrode 有权
标题翻译：铜电极的制造方法
公开(公告)号：US08647815B1
公开(公告)日：2014-02-11
申请号：US13558912
申请日：2012-07-26
申请人： Masakatsu Kuroki , Takeshi Kono
发明人： Masakatsu Kuroki , Takeshi Kono
IPC分类号： G03F7/26
CPC分类号： C23C18/1216
摘要： A method for manufacturing an electrode comprising the steps of: applying onto a substrate a conductive paste to form a conductive paste layer comprising; (i) 100 parts by weight of a copper powder coated with a metal oxide selected from the group consisting of silicon oxide (SiO2), zinc oxide (ZnO), aluminum oxide (Al2O3), titanium oxide (TiO2), magnesium oxide (MgO) and a mixture thereof; (ii) 5 to 30 parts by weight of a boron powder; and (iii) 0.1 to 10 parts by weight of a glass frit; dispersed in (iv) an organic vehicle; and firing the conductive paste in air.
摘要翻译：一种用于制造电极的方法，包括以下步骤：在基底上施加导电膏以形成导电浆料层，其包括：（i）100重量份涂覆有选自氧化硅（SiO 2），氧化锌（ZnO），氧化铝（Al 2 O 3），氧化钛（TiO 2），氧化镁（MgO））及其混合物; （ii）5〜30重量份的硼粉末; 和（iii）0.1至10重量份的玻璃料; 分散在（iv）有机载体中; 并在空气中烧制导电膏。

9. 发明申请

US20120239955A1 ELECTRONIC DEVICE 有权
标题翻译：电子设备
公开(公告)号：US20120239955A1
公开(公告)日：2012-09-20
申请号：US13394592
申请日：2010-08-25
申请人： Kazuhiro Yanase , Takeshi Kono , Motoki Kobayashi
发明人： Kazuhiro Yanase , Takeshi Kono , Motoki Kobayashi
IPC分类号： G06F1/32 , G06F1/16
CPC分类号： G06F1/1677 , A63F2300/1043 , A63F2300/204 , A63F2300/636 , G06F1/1624 , G06F1/3203 , H04M1/0235 , H04M1/0245 , H04M1/236 , H04M1/67 , H04W52/0254 , Y02D70/00
摘要： An opening/closing detection unit detects a transition of an electronic device from an open state to a closed state or from the closed state to the open state. An electrical-power control unit sets an operation mode of an application processing unit that executes an application. When a transition from the open state to the closed state is detected while a hold switch is in an OFF state, the electrical-power control unit switches an operation mode of an application processing unit from a normal mode to a sleep mode. On the other hand, when a transition from the open state to the closed state is detected while the hold switch is in an ON state, the electrical-power control unit does not switch the operation mode of the application processing unit from the normal mode to the sleep mode.
摘要翻译：打开/关闭检测单元检测电子设备从打开状态到关闭状态或从关闭状态到打开状态的转变。电力控制单元设置执行应用的应用处理单元的操作模式。当保持开关处于OFF状态时，当检测到从打开状态到关闭状态的转变时，电力控制单元将应用处理单元的操作模式从正常模式切换到睡眠模式。另一方面，当保持开关处于接通状态时，当检测到从打开状态到关闭状态的转变时，电力控制单元不将应用处理单元的操作模式从正常模式切换到睡眠模式。

10. 发明授权

US4949033A LSI system including a plurality of LSI circuit chips mounted on a board 失效
标题翻译： LSI系统包括安装在板上的多个LSI电路芯片
公开(公告)号：US4949033A
公开(公告)日：1990-08-14
申请号：US354364
申请日：1989-05-19
申请人： Takeshi Kono , Tatsuro Yoshimura
发明人： Takeshi Kono , Tatsuro Yoshimura
IPC分类号： G01R31/319 , G01R31/28 , G01R31/316
CPC分类号： G01R31/2818 , G01R31/316
摘要： An LSI system includes; a multi-layer print board; and a plurality of LSI circuit chips mounted on the multi-layer printed circuit board, each including a plurality of pins, a reference voltage terminal, a pin scan out terminal and a plurality of pin scan out circuits corresponding to the pins on a one-to-one basis. The multi-layer printed circuit board includes a reference voltage feeding layer formed therein in a form of a mesh or a sheet, at least one further layer overlying the reference voltage feeding layer and a plurality of through holes extending through each such further layer. By electrically connecting each reference voltage terminal of the plurality of LSI circuit chips through a corresponding through hole to the reference voltage feeding layer, a substantially equal reference voltage can be fed to each LSI and the voltage drop thereof is reduced.

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