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1. 发明授权

US08957088B2 4-dimethylamino-phenyl-substituted naphthyridines, and use thereof as medicaments 有权
标题翻译： 4-二甲基氨基 - 苯基取代的萘啶，及其用作药物
公开(公告)号：US08957088B2
公开(公告)日：2015-02-17
申请号：US14071016
申请日：2013-11-04
申请人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
发明人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
IPC分类号： A61K31/4375 , C07D471/04 , C07D519/00
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 and R6 may have the meanings as described in claim 1, as well as medicaments which contain these compounds. Further, the invention relates to methods of treating a disease selected from asthma, COPD, allergic rhinitis, adult respiratory distress syndrome, bronchitis, allergic dermatitis, contact dermatitis, idiopathic thrombocytopenic purpura, rheumatoid arthritis and allergic rhinoconjunctivitis by administrating an appropriate amount of a compound of formula 1 to a patient in need thereof.
摘要翻译：本发明涉及式1的新的取代的萘啶，以及其药学上可接受的盐，非对映异构体，对映异构体，外消旋体，水合物或溶剂合物，其中R 1和R 6可以具有权利要求1所述的含义，以及含有这些化合物。此外，本发明涉及通过施用适量的化合物治疗选自哮喘，COPD，变应性鼻炎，成人呼吸窘迫综合征，支气管炎，过敏性皮炎，接触性皮炎，特发性血小板减少性紫癜，类风湿性关节炎和过敏性鼻炎的疾病的方法式1给有需要的患者。

2. 发明申请

US20140148484A1 PYRAZOLE COMPOUNDS FOR TREATING HAIRLOSS 审中-公开
标题翻译：用于治疗头发的吡咯化合物
公开(公告)号：US20140148484A1
公开(公告)日：2014-05-29
申请号：US14082257
申请日：2013-11-18
申请人： Andreas SCHNAPP , Jeffrey Adam ENCINAS , Andy FOWLER , Takeshi KONO , Katsuhiro UTO
发明人： Andreas SCHNAPP , Jeffrey Adam ENCINAS , Andy FOWLER , Takeshi KONO , Katsuhiro UTO
IPC分类号： A61K8/49 , A61Q7/00
CPC分类号： A61Q7/00 , A61K8/494 , A61K31/415 , C07D231/12
摘要： The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof for use in the treatment or prevention of hairloss, wherein W, L1, L2, X, L3, Y, R1 and R2 have one of the meanings as indicated in the specification and claims, to pharmaceutical compositions containing said compounds or pharmaceutically acceptable salts thereof, to the use of said compounds or pharmaceutically acceptable salts thereof for the manufacture of a medicament useful for the treatment or prevention of hairloss, to a method of treating or preventing hairloss as well as to a method of stimulating hair growth.
摘要翻译：本发明涉及用于治疗或预防脱发的式（I）化合物或其药学上可接受的盐，其中W，L 1，L 2，X，L 3，Y，R 1和R 2具有如说明书和权利要求书，涉及含有所述化合物或其药学上可接受的盐的药物组合物用于制备用于治疗或预防脱发的药物的所述化合物或其药学上可接受的盐，治疗或预防的方法脱发以及刺激头发生长的方法。

3. 发明授权

US08647815B1 Method of manufacturing copper electrode 有权
标题翻译：铜电极的制造方法
公开(公告)号：US08647815B1
公开(公告)日：2014-02-11
申请号：US13558912
申请日：2012-07-26
申请人： Masakatsu Kuroki , Takeshi Kono
发明人： Masakatsu Kuroki , Takeshi Kono
IPC分类号： G03F7/26
CPC分类号： C23C18/1216
摘要： A method for manufacturing an electrode comprising the steps of: applying onto a substrate a conductive paste to form a conductive paste layer comprising; (i) 100 parts by weight of a copper powder coated with a metal oxide selected from the group consisting of silicon oxide (SiO2), zinc oxide (ZnO), aluminum oxide (Al2O3), titanium oxide (TiO2), magnesium oxide (MgO) and a mixture thereof; (ii) 5 to 30 parts by weight of a boron powder; and (iii) 0.1 to 10 parts by weight of a glass frit; dispersed in (iv) an organic vehicle; and firing the conductive paste in air.
摘要翻译：一种用于制造电极的方法，包括以下步骤：在基底上施加导电膏以形成导电浆料层，其包括：（i）100重量份涂覆有选自氧化硅（SiO 2），氧化锌（ZnO），氧化铝（Al 2 O 3），氧化钛（TiO 2），氧化镁（MgO））及其混合物; （ii）5〜30重量份的硼粉末; 和（iii）0.1至10重量份的玻璃料; 分散在（iv）有机载体中; 并在空气中烧制导电膏。

4. 发明授权

US08604049B2 4-dimethylamino-phenyl-substituted naphthyridines, and use thereof as medicaments 有权
标题翻译： 4-二甲基氨基 - 苯基取代的萘啶，及其用作药物
公开(公告)号：US08604049B2
公开(公告)日：2013-12-10
申请号：US13057330
申请日：2009-07-23
申请人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
发明人： Dennis Fiegen , Sandra Handschuh , Silke Hobbie , Matthias Hoffmann , Takeshi Kono , Yayoi Sato , Andreas Schnapp , Annette Schuler-Metz
IPC分类号： A61K31/573 , A61K31/4375 , A61P11/00 , A61P19/10 , A61P1/04 , A61P31/14 , A61P7/06 , A61P25/00 , A61P19/02 , C07D471/04
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to novel substituted naphthyridines of formula 1 as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates, or solvates thereof. In formula 1, R1 can represent a group A selected from among the group comprising —O—R3, —NR3R4, —CR3R4R5, -(ethyne)-R3, —S—R3, —SO—R3, and SO2—R3, or R1 represents a group B selected from among the group comprising: —C6-10-aryl; —a five-membered to ten-membered, monocyclic or bicyclic heteroaryl containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heteroaryl is linked to the structure according to formula 1 via a C atom or an N atom; —a three-membered to ten-membered, monocyclic or bicyclic, saturated or partially saturated heterocycle containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heterocycle is linked to the structure according to formula 1 via a C atom or an N atom; and —a 5-membered to 11-membered spiro group which can optionally contain 1, 2, or 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said spiro group is linked to the structure according to formula 1 via a C atom or an N atom, wherein said group B can be optionally substituted as described in claims 1, and R3, R4, R5, R6, and m can have the meanings indicated in claim 1. The invention also relates to pharmaceutical compositions containing said compounds.
摘要翻译：本发明涉及式1的新型取代萘啶以及其药理学上可接受的盐，非对映异构体，对映异构体，外消旋物，水合物或溶剂合物。在式1中，R 1可以表示选自-O-R 3，-NR 3 R 4，-CR 3 R 4 R 5， - （乙炔）-R 3，-S-R 3，-SO-R 3和SO 2 -R 3的基团A，或 R 1表示选自以下的基团B：-C 6-10 - 芳基; 包含1至3个独立地选自N，O和S的杂原子的五元至十元单环或二环杂芳基，其中所述杂芳基通过C原子连接至根据式1的结构，或一个N原子; 包含1-3个独立地选自包括N，O和S的杂原子的3至10元，单环或双环饱和或部分饱和的杂环，其中所述杂环与根据式1的结构连接通过C原子或N原子; 和可以任选地含有1,2或3个独立地选自N，O和S的组的杂原子的5元至11元螺环，其中所述螺环与根据式1的结构连接通过C原子或N原子，其中所述基团B可以如权利要求1所述任选被取代，并且R 3，R 4，R 5，R 6和m可以具有权利要求1中所示的含义。本发明还涉及药物组合物含有所述化合物。

5. 发明申请

US20120239955A1 ELECTRONIC DEVICE 有权
标题翻译：电子设备
公开(公告)号：US20120239955A1
公开(公告)日：2012-09-20
申请号：US13394592
申请日：2010-08-25
申请人： Kazuhiro Yanase , Takeshi Kono , Motoki Kobayashi
发明人： Kazuhiro Yanase , Takeshi Kono , Motoki Kobayashi
IPC分类号： G06F1/32 , G06F1/16
CPC分类号： G06F1/1677 , A63F2300/1043 , A63F2300/204 , A63F2300/636 , G06F1/1624 , G06F1/3203 , H04M1/0235 , H04M1/0245 , H04M1/236 , H04M1/67 , H04W52/0254 , Y02D70/00
摘要： An opening/closing detection unit detects a transition of an electronic device from an open state to a closed state or from the closed state to the open state. An electrical-power control unit sets an operation mode of an application processing unit that executes an application. When a transition from the open state to the closed state is detected while a hold switch is in an OFF state, the electrical-power control unit switches an operation mode of an application processing unit from a normal mode to a sleep mode. On the other hand, when a transition from the open state to the closed state is detected while the hold switch is in an ON state, the electrical-power control unit does not switch the operation mode of the application processing unit from the normal mode to the sleep mode.
摘要翻译：打开/关闭检测单元检测电子设备从打开状态到关闭状态或从关闭状态到打开状态的转变。电力控制单元设置执行应用的应用处理单元的操作模式。当保持开关处于OFF状态时，当检测到从打开状态到关闭状态的转变时，电力控制单元将应用处理单元的操作模式从正常模式切换到睡眠模式。另一方面，当保持开关处于接通状态时，当检测到从打开状态到关闭状态的转变时，电力控制单元不将应用处理单元的操作模式从正常模式切换到睡眠模式。

6. 发明授权

US4949033A LSI system including a plurality of LSI circuit chips mounted on a board 失效
标题翻译： LSI系统包括安装在板上的多个LSI电路芯片
公开(公告)号：US4949033A
公开(公告)日：1990-08-14
申请号：US354364
申请日：1989-05-19
申请人： Takeshi Kono , Tatsuro Yoshimura
发明人： Takeshi Kono , Tatsuro Yoshimura
IPC分类号： G01R31/319 , G01R31/28 , G01R31/316
CPC分类号： G01R31/2818 , G01R31/316
摘要： An LSI system includes; a multi-layer print board; and a plurality of LSI circuit chips mounted on the multi-layer printed circuit board, each including a plurality of pins, a reference voltage terminal, a pin scan out terminal and a plurality of pin scan out circuits corresponding to the pins on a one-to-one basis. The multi-layer printed circuit board includes a reference voltage feeding layer formed therein in a form of a mesh or a sheet, at least one further layer overlying the reference voltage feeding layer and a plurality of through holes extending through each such further layer. By electrically connecting each reference voltage terminal of the plurality of LSI circuit chips through a corresponding through hole to the reference voltage feeding layer, a substantially equal reference voltage can be fed to each LSI and the voltage drop thereof is reduced.

7. 发明授权

US08682048B2 Image processing device, image processing method, computer-readable recording device 有权
标题翻译：图像处理装置，图像处理方法，计算机可读记录装置
公开(公告)号：US08682048B2
公开(公告)日：2014-03-25
申请号：US13343796
申请日：2012-01-05
申请人： Masashi Hirota , Yamato Kanda , Makoto Kitamura , Takeshi Kono
发明人： Masashi Hirota , Yamato Kanda , Makoto Kitamura , Takeshi Kono
IPC分类号： G06K9/00 , A61B1/04
CPC分类号： G06T7/12 , G06T7/11 , G06T2207/10068 , G06T2207/30028 , G06T2207/30092
摘要： In an image processing device that discriminates between a mucosal region and a non-mucosal region that are contained in an intraluminal image, the image processing device includes a residue candidate region detecting unit that detects a residue candidate region to be discriminated whether the candidate region is a mucosal region or not, on the basis of a feature data of each pixel that constitutes the intraluminal image, a structure edge region detecting unit that detects a structure edge contained in the intraluminal image, and an approximate structure edge line calculating unit and an overlap deciding unit that discriminate whether the residue candidate region is a mucosal region or not, based on a relative positional relationship between the structure edge and the residue candidate region.
摘要翻译：在区分管腔内图像中所含的粘膜区域和非粘膜区域的图像处理装置中，图像处理装置包括：残差候选区域检测单元，其对残留候选区域进行检测，判别候选区域是否为基于构成管腔内图像的每个像素的特征数据的粘膜区域，检测管腔内图像中包含的结构边缘的结构边缘区域检测单元，以及近似结构边缘线计算单元和重叠区域基于结构边缘和残留候选区域之间的相对位置关系来区分残留候选区域是否为粘膜区域的判定单元。

8. 发明申请

US20120190459A1 GAME APPARATUS, GAME INTERRUPTION PROGRAM, STORAGE MEDIUM STORED WITH GAME INTERRUPTION PROGRAM 有权
标题翻译：游戏设备，游戏中断程序，存储游戏中断程序的存储介质
公开(公告)号：US20120190459A1
公开(公告)日：2012-07-26
申请号：US13392141
申请日：2010-07-21
申请人： Motoki Kobayashi , Takeshi Kono
发明人： Motoki Kobayashi , Takeshi Kono
IPC分类号： A63F9/24
CPC分类号： A63F13/493 , A63F13/10 , A63F2300/206 , A63F2300/636
摘要： A game execution unit 101 of a game apparatus 2 executes game processing in conformity with predetermined setting information including a game program, and terminates the game processing in progress in response to a command for temporary interruption from a user. A storage control unit 102 restores the state at the time of game termination by the game execution unit 101, and stores in a storage unit 107 interruption information allowing resumption of the game processing in conformity with the command for temporary interruption from the user. A setting changing unit 103 changes the predetermined setting information in response to a change command from the user. The storage control unit 102 deletes the interruption information stored in the storage unit 107 in accordance with setting change carried out by the setting changing unit 103.
摘要翻译：游戏装置2的游戏执行单元101根据包括游戏程序的预定设置信息来执行游戏处理，并且响应于用户的临时中断命令终止正在进行的游戏处理。存储控制单元102恢复由游戏执行单元101进行的游戏终止时的状态，并且在存储单元107中存储允许恢复游戏处理的中断信息，这符合从用户暂时中断的命令。设置改变单元103响应于来自用户的改变命令改变预定设置信息。存储控制单元102根据由设置改变单元103执行的设置改变删除存储在存储单元107中的中断信息。

9. 发明授权

US07805596B2 Highly integrated multiprocessor system 有权
标题翻译：高度集成的多处理器系统
公开(公告)号：US07805596B2
公开(公告)日：2010-09-28
申请号：US10587553
申请日：2005-10-31
申请人： Shinji Noda , Takeshi Kono
发明人： Shinji Noda , Takeshi Kono
IPC分类号： G06F9/00 , G06F9/44
CPC分类号： G06F9/4812 , G06F9/322 , G06F9/3879
摘要： In a multi-processor system (100), when a first processor interrupt generation unit (24) has executed a call command or a jump command in a main routine being executed, it generates an interrupt to a second processor. Upon reception of the interrupt from the interrupt generation unit (24), the second processor saves the return address for returning to the main routing upon completion of the subroutine processing called by the call command in a main memory area (54) other than the first processor or generates a call destination address and a jump destination address and reports it to the first processor. Thus, the first processor can be a small-size circuit capable of flexibly performing processing.
摘要翻译：在多处理器系统（100）中，当第一处理器中断产生单元（24）执行正在执行的主程序中的调用命令或跳转命令时，它向第二处理器产生中断。在从中断生成单元（24）接收到中断时，第二处理器在除了第一个主存储区域（54）之外的主存储区域（54）中完成由呼叫命令调用的子程序处理之后，保存用于返回主路由的返回地址处理器或生成呼叫目的地地址和跳转目标地址并将其报告给第一处理器。因此，第一处理器可以是能够灵活地执行处理的小尺寸电路。

10. 发明授权

US06805437B2 Liquid supply system, ink jet recording head, ink jet recording apparatus and liquid filling method 有权
标题翻译：液体供应系统，喷墨记录头，喷墨记录装置和液体填充方法
公开(公告)号：US06805437B2
公开(公告)日：2004-10-19
申请号：US10066623
申请日：2002-02-06
申请人： Akihiro Yamanaka , Mitsuru Kurata , Yutaka Koizumi , Hiroyuki Maeda , Takeaki Shima , Akira Goto , Takeshi Kono , Tetsuto Kageyama , Itaru Watanabe , Hiroki Tajima , Yasushi Iijima , Toshihiro Sasaki
发明人： Akihiro Yamanaka , Mitsuru Kurata , Yutaka Koizumi , Hiroyuki Maeda , Takeaki Shima , Akira Goto , Takeshi Kono , Tetsuto Kageyama , Itaru Watanabe , Hiroki Tajima , Yasushi Iijima , Toshihiro Sasaki
IPC分类号： B41J219
CPC分类号： B41J2/17509
摘要： The invention prevents drawbacks resulting from the bubble generated at the downstream side of the filter, while minimizing the waste in the ink. The recording head has a sub tank for storing ink supplied from the exterior, and a liquid chamber storing the ink supplied from the sub tank and supplying ink directly to a nozzle for ink discharge. A filter is provided between the sub tank and the liquid chamber. The liquid chamber holds ink of a predetermined amount in such a manner that the ink therein is separated by gas between the filter and the liquid chamber.
摘要翻译：本发明防止了在过滤器的下游侧产生的气泡的缺点，同时使油墨中的废物最小化。记录头具有用于存储从外部供应的油墨的副罐和储存从副罐供给的油墨并将油墨直接供给到用于油墨排出的喷嘴的液体室。在副罐和液室之间提供过滤器。液体室保持预定量的油墨，使得其中的油墨在过滤器和液体室之间被气体分离。

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