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1. 发明申请

US20080304994A1 Scroll Fluid Machine 审中-公开
标题翻译：涡旋流体机
公开(公告)号：US20080304994A1
公开(公告)日：2008-12-11
申请号：US12136804
申请日：2008-06-11
申请人： Masaru OHTAHARA , Masashi Miyake , Kenji Tojo , Kazuo Sakurai
发明人： Masaru OHTAHARA , Masashi Miyake , Kenji Tojo , Kazuo Sakurai
IPC分类号： F04C18/02 , F04C29/02
CPC分类号： F04C18/0215 , F04C23/008 , F04C27/007
摘要： A scroll fluid machine is configured by engaging a fixed scroll and an orbiting scroll having spiral bodies formed on base plates. A seal member is provided between a rear surface of the orbiting scroll and a frame member arranged opposite thereto to divide a rear side chamber into an inner space and an outer space. The inner space inside the seal member is subjected to a pressure substantially corresponding to a discharge pressure, and the outer space is subjected to a pressure lower than that of an inner back pressure chamber to press the orbiting scroll against the fixed scroll. The scroll members are formed such that the width of a groove and the thickness of a tooth of the spiral body formed inside the seal member are larger than those of the spiral body formed outside the seal member.
摘要翻译：涡旋流体机构通过使固定涡旋件和具有形成在基板上的螺旋体的绕动涡旋盘构成。在动涡旋盘的后表面和与其相对设置的框架构件之间设置密封构件，以将后侧室分成内部空间和外部空间。密封构件内的内部空间经受基本上对应于排出压力的压力，并且外部空间受到比内侧背压室低的压力，以将动涡旋件压靠在固定涡旋件上。涡旋构件形成为使得形成在密封构件内部的槽的宽度和螺旋体的齿的厚度大于形成在密封构件外部的螺旋体的宽度。

2. 发明授权

US5277564A Closed type scroll compressor with spherical slide bearing for the oil tube 失效
标题翻译：闭式涡旋压缩机，带有油管球面滑动轴承
公开(公告)号：US5277564A
公开(公告)日：1994-01-11
申请号：US913833
申请日：1992-07-16
申请人： Takahiro Tamura , Kazuo Sakurai , Masashi Miyake , Mutsunori Matsunaga
发明人： Takahiro Tamura , Kazuo Sakurai , Masashi Miyake , Mutsunori Matsunaga
IPC分类号： F04C18/02 , F04C28/02 , F04C29/00 , F04C29/02 , F04C29/12 , F16L27/04 , F04C18/04 , F04C23/00
CPC分类号： F04C29/023 , F04C18/0215 , F16L27/04
摘要： A closed type scroll compressor has a drive shaft supported by a frame through bearings lubricated with a lubricating oil supplied from an oil reservoir via a lubricating oil passage bore formed in the drive shaft. The end of the drive shaft in which the upstream end of the lubricating oil passage bore opens is connected to the oil reservoir through a joint tube which is supported by supporting structures including a combination of a spherical slide bearing and slide bearing and capable of taking up any mounting error or displacement of the drive shaft in any direction. The compressor can be assembled easily without any risk of uneven or local contact of each sliding portion.
摘要翻译：封闭式涡旋压缩机具有由框架支撑的驱动轴，所述驱动轴通过经由形成在所述驱动轴中的润滑油通道孔从由储油器供应的润滑油润滑的轴承。驱动轴的端部，其中润滑油通道孔的上游端打开，其通过连接管连接到储油器，接头管由支撑结构支撑，该支撑结构包括球形滑动轴承和滑动轴承的组合，并且能够承载驱动轴在任何方向的任何安装误差或位移。可以容易地组装压缩机，而不会有每个滑动部分不均匀或局部接触的风险。

3. 发明授权

US09801929B2 Immune tolerance inducer 有权
公开(公告)号：US09801929B2
公开(公告)日：2017-10-31
申请号：US14237763
申请日：2012-07-13
申请人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
发明人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
IPC分类号： A61K31/70 , C07H21/02 , C07H21/04 , A61K39/00 , A61K31/7105 , A61K31/716 , C12N15/11 , C12N15/113 , C12N5/00
CPC分类号： A61K39/0013 , A61K31/7105 , A61K31/716 , A61K2039/57 , C12N15/111 , C12N15/113 , C12N15/1138 , C12N2310/315 , C12N2320/32 , C12N2320/50 , C12N2310/14 , C12N2310/3519
摘要： An object of the present invention is to provide a drug and a method for effectively inducing donor-specific immune tolerance in a recipient in transplantation therapy. A complex of an siRNA for a costimulatory factor and schizophyllan is delivered to a Dectin-1 expressing cell which specifically recognizes schizophyllan to regulate the function of the Dectin-1 expressing cell, and therefore can induce immunosuppression effect as well as induce immune tolerance effectively.

4. 发明授权

US09713636B2 Nucleic acid/polysaccharide complex 有权
公开(公告)号：US09713636B2
公开(公告)日：2017-07-25
申请号：US14001694
申请日：2012-02-15
申请人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
发明人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
IPC分类号： A61K31/70 , C07H21/02 , C07H21/04 , A61K39/00 , A61K31/7105 , A61K31/716 , C12N15/11 , C12N15/113 , C12N5/00
CPC分类号： A61K39/0013 , A61K31/7105 , A61K31/716 , A61K2039/57 , C12N15/111 , C12N15/113 , C12N15/1138 , C12N2310/315 , C12N2320/32 , C12N2320/50 , C12N2310/14 , C12N2310/3519
摘要： A highly stable nucleic acid-polysaccharide complex of an siRNA and schizophyllan is formed by adding polydeoxyadenine in which at least part of the phosphodiester link portion is phosphorothioated to an siRNA and allowing the siRNA and schizophyllan to form a complex.

5. 发明授权

US07935683B2 Polysaccharide-carbon nanotube complex 失效
标题翻译：多糖 - 碳纳米管复合物
公开(公告)号：US07935683B2
公开(公告)日：2011-05-03
申请号：US11579403
申请日：2006-05-16
申请人： Masami Mizu , Seiji Shinkai , Teruaki Hasegawa , Munenori Numata , Tomohisa Fujisawa , Kazuo Sakurai
发明人： Masami Mizu , Seiji Shinkai , Teruaki Hasegawa , Munenori Numata , Tomohisa Fujisawa , Kazuo Sakurai
IPC分类号： A61K31/715 , A61K31/716 , C08B37/00 , B82B1/00 , B82B3/00
CPC分类号： C08B37/0024 , B82Y30/00 , B82Y40/00 , C01B32/168 , C01B2202/02 , C08B33/00 , C08B37/0057 , Y10S977/75 , Y10S977/753
摘要： Disclosed is a complex which comprises a carbon nanotube and a modified polysaccharide having a backbone chain with the side thereof being introduced with monosaccharide or oligosaccharide residues. The polysaccharide is preferably β-1,3-glucan. The complex is prepared by admixing a solution of the modified polysaccharide dissolved in an aprotic polar solvent or a strong alkali solution with an aqueous dispersion of the carbon nanotube, and incubating the mixture.
摘要翻译：公开了一种络合物，其包含碳纳米管和具有主链的改性多糖，其侧面被引入单糖或寡糖残基。多糖优选为-1,3-β-葡聚糖。通过将溶解在非质子极性溶剂或强碱溶液中的改性多糖的溶液与碳纳米管的水性分散体混合并将该混合物混合来制备络合物。

6. 发明授权

US5110268A Lubricant supply system of a scroll fluid machine 失效
标题翻译：滚动流体机械的润滑剂供应系统
公开(公告)号：US5110268A
公开(公告)日：1992-05-05
申请号：US620613
申请日：1990-12-03
申请人： Kazuo Sakurai , Takahiro Tamura
发明人： Kazuo Sakurai , Takahiro Tamura
IPC分类号： F01C1/02 , F04C18/02 , F04C29/02
CPC分类号： F01C1/0215 , F04C18/0215 , F04C29/02
摘要： A scroll compressor has a scroll mechanism disposed in a closed container and driven by a motor through a crank shaft rotatably supported at two points by first and second bearings disposed adjacent the opposite ends of the motor. The bearing which is remote from the scroll mechanism comprises a sliding bearing. The first end of the crank shaft remote from the scroll mechanism has a peripheral surface disposed in sliding engagement with the sliding bearing and formed therein with a lubricant supply groove communicated with an axial lubricant supply hole formed in the crank shaft and having a closed end adjacent the first end of the crank shaft and opened in an end face of a crank pin section thereof. The sliding bearing is communicated with a lubricant reservoir formed by a lower part of the container. The lubricant in the reservoir is subjected to the pressure of a compressed fluid discharged from the scroll mechanism and is forcibly fed into the lubricant supply groove through the sliding bearing.
摘要翻译：涡旋压缩机具有设置在密闭容器中的涡旋机构，并且由电动机驱动，所述曲轴通过与所述马达的相对端相邻设置的第一和第二轴承可旋转地支撑在两点上。远离涡旋机构的轴承包括滑动轴承。曲柄轴远离涡旋机构的第一端具有与滑动轴承滑动接合的周面，并在其中形成有与形成在曲轴中的轴向润滑剂供给孔连通并具有相邻的封闭端的润滑剂供给槽曲柄轴的第一端并在其曲柄销部分的端面中敞开。滑动轴承与由容器的下部形成的润滑剂储存器连通。储存器中的润滑剂受到从涡旋机构排出的压缩流体的压力，并通过滑动轴承强制地进入润滑剂供给槽。

7. 发明授权

US4997350A Scroll fluid machine with bearing lubrication 失效
标题翻译：滚动式流体机，带轴承润滑
公开(公告)号：US4997350A
公开(公告)日：1991-03-05
申请号：US306401
申请日：1989-02-06
申请人： Takahiro Tamura , Kazuo Sakurai
发明人： Takahiro Tamura , Kazuo Sakurai
IPC分类号： F04C29/02
CPC分类号： F04C29/025
摘要： A compressor unit composed of a fixed scroll and an orbiting scroll which are engaged with each other, and a variable speed motor are disposed in a hermetic chamber. A first bearing is provided in an engagement portion between a crankshaft and the orbiting scroll in an intermediate pressure chamber provided on a back surface of the orbiting scroll for applying thereto an intermediate pressure between a discharge pressure and a suction pressure. The crankshaft is supported by a second bearing provided close to the orbiting scroll and a third bearing provided close to the motor. The first, second and third bearings are lubricated by force of a differential pressure between the discharge pressure and the intermediate pressure through an oil passage. The oil passage is in communication at one end thereof with the lubricant oil on which the discharge pressure is applied, and opens at the other end thereof into the intermediate pressure chamber. Thus, a wear and a sticking of the bearings are prevented even in a low speed region and a high speed region where it is impossible to supply oil with a conventional centrifugal pump.
摘要翻译：由彼此接合的固定涡旋盘和绕动涡旋件构成的压缩机单元和变速马达设置在密封室中。第一轴承设置在设置在绕动涡盘的后表面上的中间压力室中的曲轴和绕动涡旋件之间的接合部分中，用于向排出压力和吸入压力施加中间压力。曲轴由靠近绕动涡盘设置的第二轴承和靠近马达设置的第三轴承支撑。第一，第二和第三轴承由排出压力和通过油路的中间压力之间的压差的力来润滑。油路在其一端与施加有排出压力的润滑油连通，并且在其另一端开入中间压力室。因此，即使在不能用现有的离心泵供给油的低速区域和高速区域也能够防止轴承的磨损和粘附。

8. 发明授权

US4818198A Scroll fluid machine with oil feed passages 失效
标题翻译：带进油通道的滚动流体机
公开(公告)号：US4818198A
公开(公告)日：1989-04-04
申请号：US120098
申请日：1987-11-13
申请人： Takahiro Tamura , Kazuo Sakurai
发明人： Takahiro Tamura , Kazuo Sakurai
IPC分类号： F01C1/02 , F01C1/04 , F01C21/04 , F04B39/02 , F04C18/02 , F04C29/02 , F04C18/04
CPC分类号： F04C29/025 , F04C18/0215
摘要： A scroll fluid machine comprising a pair of fixed and orbiting scrolls having their respective wraps in mesh with each other. A drive shaft engaging the orbiting scroll is connected to an electric motor and is supported by a frame. An end plate of the oribiting scroll is slidably held between the frame and an end plate of the fixed scroll. A first feed oil passage is formed in at least one of the end plate of the fixed scroll and the frame. The first passage has one end communicates with an oil reservoir defined at a bottom of the housing and the other end opening on a sliding surface contacting with the orbiting scroll. A second feed oil passage formed in the end plate of the orbiting scroll has one end always communicating with the other end of the first passage. The other end of the second passage is located in the vicinity of the axis of the orbiting scroll. A third feed oil passage formed in the drive shaft has one end communicating with the other end of the second passage.
摘要翻译：一种涡旋流体机械，包括一对具有彼此啮合的相互缠绕的固定和绕动的涡卷。接合绕动涡旋件的驱动轴连接到电动机并由框架支撑。蜗杆蜗杆的端板可滑动地保持在框架和固定涡卷的端板之间。第一进料油通道形成在固定涡旋件的端板和框架中的至少一个中。第一通道的一端与限定在壳体的底部的油储存器连通，而另一端开口与与绕动涡旋件接触的滑动表面连通。形成在绕动涡旋盘的端板中的第二进料油通道具有总是与第一通道的另一端连通的一端。第二通道的另一端位于绕动涡盘的轴线附近。形成在驱动轴上的第三供给油通道具有与第二通道的另一端连通的一端。

9. 发明申请

US20140128448A1 NUCLEIC ACID/POLYSACCHARIDE COMPLEX 有权
标题翻译：核酸/多糖复合物
公开(公告)号：US20140128448A1
公开(公告)日：2014-05-08
申请号：US14001694
申请日：2012-02-15
申请人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
发明人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
IPC分类号： C12N15/113
CPC分类号： A61K39/0013 , A61K31/7105 , A61K31/716 , A61K2039/57 , C12N15/111 , C12N15/113 , C12N15/1138 , C12N2310/315 , C12N2320/32 , C12N2320/50 , C12N2310/14 , C12N2310/3519
摘要： An object of the present invention is to provide a highly stable nucleic acid-polysaccharide complex of an siRNA and schizophyllan. A nucleic acid-polysaccharide complex is formed by adding polydeoxyadenine in which at least part of the phosphodiester link portion is phosphorothioated to an siRNA and allowing the siRNA and schizophyllan to form a complex.
摘要翻译：本发明的目的是提供siRNA和分裂片菌素的高度稳定的核酸 - 多糖复合物。核酸 - 多糖复合物是通过加入其中至少部分磷酸二酯连接部分被硫代磷酸化的多脱氧腺嘌呤形成的，并允许siRNA和裂刺菌素形成复合物。

10. 发明申请

US20130267576A1 (NUCLEIC ACID)-POLYSACCHARIDE COMPLEX 审中-公开
标题翻译：（核酸） - 多糖复合物
公开(公告)号：US20130267576A1
公开(公告)日：2013-10-10
申请号：US13810533
申请日：2011-07-12
申请人： Kazuo Sakurai
发明人： Kazuo Sakurai
IPC分类号： C12N15/113
CPC分类号： C12N15/113 , A61K31/7088 , A61K31/715 , A61K47/61 , C07H21/04 , C08B37/00 , C08B37/0024 , C12N15/111 , C12N2310/11 , C12N2310/315 , C12N2310/3517 , C12N2320/51 , C12N2320/53
摘要： The present invention provides a nucleic acid-polysaccharide complex that is highly stable and has reduced cytotoxicity in a high yield. That is, the present invention provides a nucleic acid-polysaccharide complex of an antisense DNA having polydeoxyadenine (dA) as a polysaccharide binding site and a polysaccharide having a β-1,3-glucan skeleton wherein at least part of phosphodiester links of the polydeoxyadenine is phosphorothioated (provided that the phosphodiester links of the antisense DNA and the polydeoxyadenine are not entirely phosphorothioated).
摘要翻译：本发明提供高度稳定且以高产率降低的细胞毒性的核酸 - 多糖复合物。也就是说，本发明提供了具有多脱氧腺嘌呤（dA）作为多糖结合位点的反义DNA和具有β-1,3-葡聚糖骨架的多糖的核酸 - 多糖复合物，其中多脱氧腺嘌呤的至少部分磷酸二酯连接是硫代磷酸化的（条件是反义DNA和多脱氧腺嘌呤的磷酸二酯链不完全硫代磷酸化）。

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