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1. 发明授权

US5157004A Polypeptides and production thereof 失效
标题翻译：多肽及其生产
公开(公告)号：US5157004A
公开(公告)日：1992-10-20
申请号：US575552
申请日：1990-08-29
申请人： Masao Sakaguchi , Susumu Honda , Osamu Nishimura
发明人： Masao Sakaguchi , Susumu Honda , Osamu Nishimura
IPC分类号： A61K38/00 , C07K14/57
CPC分类号： C07K14/57 , A61K38/00
摘要： The present invention provides a novel polypeptide which shows higher IFN-.gamma. activity than intact IFN-.gamma. and a method of producing the same.The polypeptides not only possesses a remarkable antiviral activity, antitumor activity, immunopotentiating activity etc. but also is highly stable, therefore, it can be used advantageously as pharmaceuticals etc.
摘要翻译：本发明提供了一种与完整IFN-γ相比显示更高的IFN-γ活性的新型多肽及其制备方法。该多肽不仅具有显着的抗病毒活性，抗肿瘤活性，免疫增强活性等，而且高度稳定，因此可有利地用作药物等。

2. 发明授权

US4980455A Novel polypeptides and production thereof 失效
标题翻译：新型多肽及其生产
公开(公告)号：US4980455A
公开(公告)日：1990-12-25
申请号：US136712
申请日：1987-12-22
申请人： Masao Sakaguchi , Susumu Honda , Osamu Nishimura
发明人： Masao Sakaguchi , Susumu Honda , Osamu Nishimura
IPC分类号： C12N15/09 , A61K38/00 , A61K38/21 , A61P43/00 , C07H21/04 , C07K1/22 , C07K14/52 , C07K14/555 , C07K14/57 , C12N1/20 , C12P21/02 , C12R1/19 , C12R1/865 , C12R1/91
CPC分类号： C07K14/57 , A61K38/00
摘要： The present invention provides a novel polypeptide which shows higher IFN-.gamma. activity than intact IFN-.gamma. and a method of producing the same.The polypeptides not only possess a remarkable antiviral activity, antitumor activity, immunopotentiating activity but also is highly stable, therefore, it can be used advantageously as pharmaceuticals.

3. 发明授权

US08802756B2 Low-charging fiber and method for producing the same 有权
标题翻译：低充电纤维及其制造方法
公开(公告)号：US08802756B2
公开(公告)日：2014-08-12
申请号：US13816058
申请日：2011-08-12
申请人： Yukako Kageyama , Susumu Honda , Makoto Satake , Hiroaki Kaneko
发明人： Yukako Kageyama , Susumu Honda , Makoto Satake , Hiroaki Kaneko
IPC分类号： C08K5/52
CPC分类号： D01F8/14 , C08K5/521 , D01D5/0007 , D01F1/09 , D01F6/625 , D01F6/92 , D04H1/4326 , D04H1/435 , D04H1/728
摘要： An object to be achieved by the invention is to provide a biodegradable low-charging fiber. The prevent inventors have found that when a specific amount of a specific phospholipid that is not known to have antistatic properties is added to a biodegradable polymer, and the resulting mixture is formed into a fiber having a smooth surface, low-charging properties are developed. The invention has thus been accomplished. The invention is a fiber having an average surface porosity of less than 3% and made of a biodegradable polymer that contains a specific amount of a specific phospholipid.
摘要翻译：本发明要实现的目的是提供一种可生物降解的低充电纤维。防止发明人已经发现，将特定量的不知道具有抗静电特性的特定磷脂加入可生物降解的聚合物中，并将所得混合物形成为具有光滑表面的纤维时，开发了低充电性能。从而完成了本发明。本发明是平均表面孔隙率小于3％并由含有特定量的特定磷脂的可生物降解的聚合物制成的纤维。

4. 发明申请

US20120243081A1 MICROSCOPE 有权
标题翻译：显微镜
公开(公告)号：US20120243081A1
公开(公告)日：2012-09-27
申请号：US13423634
申请日：2012-03-19
申请人： Susumu Honda
发明人： Susumu Honda
IPC分类号： G02B21/06
CPC分类号： G02B21/002 , G02B7/005 , G02B7/006 , G02B21/16 , G02B26/101
摘要： A microscope includes: an objective lens radiating laser light and illumination light onto a specimen; a first detection optical system detecting first observation light produced from the specimen when the laser light is radiated; a second detection optical system detecting second observation light produced from the specimen when the illumination light is radiated; optical elements placed so as to be capable of being inserted into or removed from a light path of the first detection optical system or the second detection optical system; a rotating turret selectively switching the optical elements to be inserted into the light path; a storage section storing correction information about a relative misalignment between the first observation light and the second observation light caused when the optical elements are switched; and a control section correcting the relative misalignment between the first observation light and the second observation light based on the correction information.
摘要翻译：显微镜包括：物镜，将激光和照明光照射到样本上; 第一检测光学系统，当激光照射时，检测从样本产生的第一观察光; 第二检测光学系统，当照射光照射时，检测从样本产生的第二观察光; 光学元件放置成能够插入或从第一检测光学系统或第二检测光学系统的光路中移除; 旋转转台选择性地切换要插入到光路中的光学元件; 存储部分，其存储关于当所述光学元件被切换时引起的所述第一观察光和所述第二观察光之间的相对未对准的校正信息; 以及控制部，其基于所述校正信息来校正所述第一观察光与所述第二观察光之间的相对未对准。

5. 发明申请

US20090221734A1 RESIN COMPOSITION AND PROCESS FOR THE PRODUCTION THEREOF 审中-公开
标题翻译：树脂组合物及其生产方法
公开(公告)号：US20090221734A1
公开(公告)日：2009-09-03
申请号：US12279018
申请日：2007-02-09
申请人： Hiroaki Kuwahara , Susumu Honda , Yoshio Bando , Chunyi Zhi , Chengchun Tang , Dmitri Golberg
发明人： Hiroaki Kuwahara , Susumu Honda , Yoshio Bando , Chunyi Zhi , Chengchun Tang , Dmitri Golberg
IPC分类号： C08K3/38
CPC分类号： C08J5/005 , B82Y30/00 , C08J3/203 , C08J3/2053 , C08J5/18 , C08J2377/00 , C08J2379/08 , C08K7/24
摘要： The object of this invention is to provide a polyamide resin composition excellent in insulating properties, mechanical properties and dimensional stability. This invention is a resin composition containing 100 parts by weight of a polyamide resin and 0.01 to 50 parts by weight of boron nitride nanotubes. The invention also includes a formed article from the resin composition and processes for the production of the resin composition and the formed article.
摘要翻译：本发明的目的是提供绝缘性能，机械性能和尺寸稳定性优异的聚酰胺树脂组合物。本发明是含有100重量份聚酰胺树脂和0.01〜50重量份氮化硼纳米管的树脂组合物。本发明还包括来自树脂组合物的成型制品和用于生产树脂组合物和成型制品的方法。

6. 发明申请

US20070273877A1 Examination Apparatus, Fluoroscopy Apparatus, Examination Method, And Experimental Method 有权
标题翻译：检查装置，荧光检查装置，检查方法和实验方法
公开(公告)号：US20070273877A1
公开(公告)日：2007-11-29
申请号：US10594311
申请日：2005-03-29
申请人： Yoshihiro Kawano , Keiji Shimizu , Minoru Sukekawa , Tsuyoshi Mochizuki , Susumu Honda , Kazuhiro Hayashi
发明人： Yoshihiro Kawano , Keiji Shimizu , Minoru Sukekawa , Tsuyoshi Mochizuki , Susumu Honda , Kazuhiro Hayashi
IPC分类号： G01J3/30 , G02B21/36
CPC分类号： G01N21/6458 , G02B21/248
摘要： Even when the magnifying power is reduced, an image can be obtained at high resolution without significantly reducing the numerical aperture, and examination accuracy is improved. There is provided a microscope examination apparatus including a light source for emitting excitation light or illumination light to a specimen placed on a stage; an objective lens opposing the stage and capable of focusing fluorescence or reflected light from the specimen; an image-forming lens for forming an image of the specimen obtained by the objective lens; and an image-capturing unit for capturing the image of the specimen forming by the image-forming lens, wherein a plurality of the objective lenses having different magnifying powers is provided, and an objective-lens switching mechanism for switching among the objective lenses is provided, and wherein a plurality of the image-forming lenses having different magnifying powers is provided, and an image-forming-lens switching mechanism for switching among the image-forming lenses 5a and 5b is provided.
摘要翻译：即使放大倍数减小，也能够以高分辨率获得图像，而不会显着降低数值孔径，提高了检查精度。提供了一种显微镜检查装置，其包括用于向放置在台架上的样本发射激发光或照明光的光源; 与舞台相对并且能够聚焦来自样本的荧光或反射光的物镜; 用于形成由所述物镜获得的所述样本的图像的图像形成透镜; 以及图像捕获单元，用于捕获由图像形成透镜形成的样本的图像，其中提供具有不同放大倍率的多个物镜，并且提供用于在物镜之间切换的物镜切换机构并且其中提供了具有不同放大倍率的多个图像形成透镜，并且提供了用于在成像透镜5a和5b之间切换的图像形成透镜切换机构。

7. 发明申请

US20070031663A1 Wholly aromatic polyamide fiber and process for producing the same 审中-公开
标题翻译：全芳族聚酰胺纤维及其制造方法
公开(公告)号：US20070031663A1
公开(公告)日：2007-02-08
申请号：US10571270
申请日：2004-09-13
申请人： Susumu Honda , Hideaki Nitta , Shunichi Matsumura , Yasushige Yagura , Hiroshi Fujita , Sadahito Hashidate
发明人： Susumu Honda , Hideaki Nitta , Shunichi Matsumura , Yasushige Yagura , Hiroshi Fujita , Sadahito Hashidate
IPC分类号： D02G3/00
CPC分类号： D01F1/10 , D01F6/905 , Y10T428/2913 , Y10T428/2927 , Y10T428/2973
摘要： A wholly aromatic polyamide fiber which has excellent mechanical properties (toughness factor) and can be produced while attaining a satisfactory operation stability in the fiber formation step. The fiber comprises 100 parts by mass of a wholly aromatic polyamide and 0.05 to 20 parts by mass of particles of a lamellar clay mineral, e.g., hectorite, saponite, stevensite, beidellite, montmorillonite, or swelling mica.
摘要翻译：一种全芳香族聚酰胺纤维，其具有优异的机械性能（韧性因子），并且可以在纤维形成步骤中获得令人满意的操作稳定性的同时制备。纤维包括100质量份全芳族聚酰胺和0.05至20质量份的层状粘土矿物例如锂蒙脱石，皂石，碳酸钙，贝得石，蒙脱石或膨润云母的颗粒。

8. 发明申请

US20060051579A1 Carbon nanotube coated with aromatic condensation polymer 失效
标题翻译：涂有芳香族缩聚物的碳纳米管
公开(公告)号：US20060051579A1
公开(公告)日：2006-03-09
申请号：US10542641
申请日：2004-01-19
申请人： Masayuki Chokai , Hiroaki Kuwahara , Satoru Ohmori , Shunichi Matsumura , Kazuhiko Sato , Susumu Honda
发明人： Masayuki Chokai , Hiroaki Kuwahara , Satoru Ohmori , Shunichi Matsumura , Kazuhiko Sato , Susumu Honda
IPC分类号： D02G3/00
CPC分类号： C09C1/565 , B82Y30/00 , B82Y40/00 , C01B32/168 , C01P2002/82 , C01P2004/13 , C01P2004/54 , C01P2004/64 , C08K9/08 , D01F11/14 , Y10T428/2933 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995 , Y10T428/2996 , Y10T428/2998
摘要： Coated carbon nanotubes coated with 0.01-100 parts by weight of at least one type of aromatic condensation polymer selected from the group consisting of wholly aromatic polyamides, wholly aromatic polyesters, aromatic polyester carbonates, aromatic polycarbonates, semi-aromatic polyesters and wholly aromatic azoles, with respect to 100 parts by weight of the carbon nanotubes, as well as a process for their production. Aromatic condensation polymer compositions comprising 0.01-100 parts by weight of the coated carbon nanotubes and 100 parts by weight of an aromatic condensation polymer, and molded articles formed using them.
摘要翻译：包含0.01-100重量份至少一种选自全芳族聚酰胺，全芳族聚酯，芳族聚酯碳酸酯，芳族聚碳酸酯，半芳族聚酯和全芳族唑的芳族缩聚物的涂覆碳纳米管，相对于100重量份的碳纳米管，以及它们的制造方法。包含0.01-100重量份涂覆的碳纳米管和100重量份的芳族缩聚物的芳族缩聚物组合物和使用它们形成的模制品。

9. 发明授权

US06956018B2 Polyoxyalkylene monoalkyl ether, process for producing the same, polymerizable polyoxyalkylene monoalkyl ether derivative, polymer of said derivative and dispersant comprising said polymer 有权
标题翻译：聚氧化烯单烷基醚，其制备方法，可聚合的聚氧化烯单烷基醚衍生物，所述衍生物的聚合物和包含所述聚合物
公开(公告)号：US06956018B2
公开(公告)日：2005-10-18
申请号：US10888992
申请日：2004-07-13
申请人： Akinori Itoh , Susumu Honda , Tatsuya Matsui , Yoshihiro Hayashi
发明人： Akinori Itoh , Susumu Honda , Tatsuya Matsui , Yoshihiro Hayashi
IPC分类号： C08F283/06 , C08G65/26 , C08L71/02 , C11D1/72 , C07C43/15 , C08J3/02 , C11D3/37
CPC分类号： C08G65/2609 , C08F283/06 , C08F283/065 , C08L71/02 , C08L2666/04
摘要： A polymerizable polyoxyalkylene monoalkyl ether derivative prepared by using a polyoxyalklene monoalkyl ether which gives, in gel permeation chromatography, a chromatogram which satisfies a relation expressed by an equation: S1/S0≦0.15, wherein S1 represents the area under a portion of the chromatogram from the start of elution to the earliest elution time when the intensity of the refractive index has a value of L/3, L representing the shortest distance between the greatest maximum point of the intensity of the refractive index and the base line and S0 represents the area under a portion of the chromatogram from the start of elution to an elution time when the intensity of the refractive index has the greatest maximum value; a process for producing the above ether comprising adjusting the content of water in a reactor, which is used in addition polymerization of alkylene oxides with addition to a monohydric alcohol, so as to satisfy an equation: Wi×(Cf−Ci)/V≦10, wherein the content of water in the reactor is obtained by placing a solvent having a content of water Ci (ppm) in an amount Wi (g) in the reactor having an inner volume V (ml), stirring the solvent to clean the reactor, removing the solvent from the reactor and obtaining a content of water Cf (ppm) in the removed solvent.
摘要翻译：通过使用聚氧化烯单烷基醚制备的可聚合的聚氧化烯单烷基醚衍生物，所述聚氧化烯单烷基醚在凝胶渗透色谱法中得到满足由下列公式表示的关系的色谱图：S＆lt; 1＆lt; > <= 0.15，其中S 1表示当折射率的强度为L / 3时的从洗脱开始到最早洗脱时间的色谱图的一部分的面积，L 代表折射率强度的最大最大点与基线之间的最短距离，S O表示从洗脱开始到洗脱时间的部分色谱图下的面积折射率的强度具有最大的最大值; 一种制备上述醚的方法，包括调节反应器中的水含量，该反应器用于加成环氧烷与一元醇的加成聚合，以满足下式：Wix（Cf-Ci）/ V <= 10，其中反应器中的水含量是通过将具有内容积V（ml）的反应器中具有含量为Wi（g）的水分量（ppm）的溶剂置于内部体积V（ml）中，搅拌溶剂来清洗反应器中，从反应器中除去溶剂，并在去除的溶剂中获得水含量Cf（ppm）。

10. 发明授权

US08791427B2 Biological-specimen observation apparatus 有权
标题翻译：生物标本观察装置
公开(公告)号：US08791427B2
公开(公告)日：2014-07-29
申请号：US12336124
申请日：2008-12-16
申请人： Susumu Honda , Chika Nakajima
发明人： Susumu Honda , Chika Nakajima
IPC分类号： G21K5/10
CPC分类号： G01N21/645 , G01N2021/6421 , G01N2021/6493
摘要： The distribution of a fluorescent material in a specimen can be observed and the fluorescent material can be obtained as clear, highly quantitative image data. A biological-specimen observation apparatus is provided which comprises a stage on which a specimen is mounted; a position detector, provided on the stage, that detects the position of the specimen; a light source that emits excitation light or illumination light onto the specimen mounted on the stage; an objective lens, disposed opposing the stage, that collects fluorescence or reflected light from the specimen; an image-forming lens that forms an image on the specimen, collected by the objective lens; an image acquisition unit that acquires the image on the specimen, formed by the image-forming lens; an image storage unit that stores the image obtained by the image acquisition unit and positional information of the specimen detected by the position detector in association with each other; and an image processing unit that performs combining processing of a plurality of the images stored by the image storage unit on the basis of the positional information stored in association with the images.
摘要翻译：可以观察到荧光材料在样品中的分布，并且可以获得作为清晰，高度定量的图像数据的荧光材料。提供一种生物样本观察装置，其包括安装有试样的台阶; 设置在台架上的检测样本位置的位置检测器; 将激发光或照明光发射到安装在舞台上的样本上的光源; 与舞台相对设置的物镜，其从样本收集荧光或反射光; 在物体上形成图像的图像形成透镜; 图像获取单元，其获取由所述图像形成透镜形成的所述样本上的图像; 图像存储单元，其存储由图像获取单元获得的图像和由位置检测器检测到的样本的位置信息彼此相关联; 以及图像处理单元，其基于与图像相关联地存储的位置信息来执行由图像存储单元存储的多个图像的组合处理。

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