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1. 发明授权

US5556642A Method for producing sustained release microsphere preparation 失效
标题翻译：缓释微球制备方法
公开(公告)号：US5556642A
公开(公告)日：1996-09-17
申请号：US89194
申请日：1993-07-12
申请人： Masao Kobayashi , Yukiko Nishioka , Takehiko Suzuki , Yashuhisa Matsukawa
发明人： Masao Kobayashi , Yukiko Nishioka , Takehiko Suzuki , Yashuhisa Matsukawa
IPC分类号： A61K9/26 , A61K9/14 , A61K9/16 , A61K9/52 , A61K47/34 , A61K9/48 , A61K9/50
CPC分类号： A61K9/146 , A61K9/1694 , Y10S514/963 , Y10T428/2985
摘要： A method for producing sustained release microsphere preparation for water-soluble medicament, which has high incorporation efficiency of the medicament and low initial burst, which comprises dissolving water-soluble pharmaceutical active ingredient and water-insoluble biodegradable polymer in one or two solvents in which both can dissolve, removing the solvent to give a solid dispersion having the water-soluble pharmaceutical active ingredient dispersed into said biodegradable polymer at molecular level, and further, dissolving said solid dispersion in an organic solvent being water-immiscible and having a boiling point of below 100.degree. C., and adding the resulting oil phase into an aqueous phase containing emulsifying agent to give O/W emulsion, and followed by removing the organic solvent from the oil phase of the resulting emulsion.
摘要翻译：一种制备水溶性药物的缓释微球制剂的方法，其具有药物的高掺入效率和低的初始爆发，其包括将水溶性药物活性成分和水不溶性生物可降解聚合物溶解在两种或两种溶剂中可以溶解，除去溶剂，得到分子量分散在所述生物降解性聚合物中的水溶性药物活性成分的固体分散体，进一步将所述固体分散体溶解在与水不混溶并且沸点低于并将得到的油相加入到含有乳化剂的水相中，得到O / W乳液，然后从所得乳液的油相中除去有机溶剂。

2. 发明授权

US5603961A Sustained release multi-core microsphere preparation and method for producing the same 失效
标题翻译：缓释多核微球制备及其制备方法
公开(公告)号：US5603961A
公开(公告)日：1997-02-18
申请号：US128692
申请日：1993-09-30
申请人： Takehiko Suzuki , Yukiko Nishioka , Yasuhisa Matsukawa , Akihiro Matsumoto , Masao Kobayashi
发明人： Takehiko Suzuki , Yukiko Nishioka , Yasuhisa Matsukawa , Akihiro Matsumoto , Masao Kobayashi
IPC分类号： A61K9/16 , A61K9/52 , A61K9/50 , A61K9/14 , B01J13/02
CPC分类号： A61K9/1694 , A61K9/1647 , Y10S514/937 , Y10S514/938 , Y10T428/2985
摘要： Sustained release multi-core microsphere preparation which shows high incorporation efficiency of medicament and can release the medicament at a specific rate, which comprises two or more biodegradable polymers and a pharmaceutically active ingredient, and has the medicament incorporated into microregions which are produced by one of these polymers (the first polymer), and these microregions are distributed in other biodegradable polymers (the second polymer), or a method for producing the same.
摘要翻译：持续释放多芯微球制剂，其显示药物的高掺入效率并且可以以特定速率释放药物，其包含两种或更多种可生物降解的聚合物和药物活性成分，并且将药物并入微区域中，所述微区域由这些聚合物（第一聚合物）和这些微区域分布在其它可生物降解的聚合物（第二聚合物）中，或其制备方法。

3. 发明申请

US20050252535A1 Substrate cleaning apparatus and method 审中-公开
标题翻译：基板清洗装置及方法
公开(公告)号：US20050252535A1
公开(公告)日：2005-11-17
申请号：US10536961
申请日：2004-05-26
申请人： Yukiko Nishioka , Koji Ato , Ryosuke Yonekura , Yoshikazu Ariga
发明人： Yukiko Nishioka , Koji Ato , Ryosuke Yonekura , Yoshikazu Ariga
IPC分类号： H01L21/304 , B08B7/00 , H01L21/00
CPC分类号： H01L21/67028 , H01L21/67051
摘要： A substrate cleaning apparatus is used for cleaning and drying a substrate such as a semiconductor wafer used in a semiconductor fabricating process or the like. The substrate cleaning apparatus includes a substrate holding mechanism (10) configured to hold the substrate (W), and a rotating mechanism (20) configured to rotate the substrate holding mechanism (10). At least one of components of the substrate cleaning apparatus has a surface structure to which droplets are hardly attached.
摘要翻译：基板清洗装置用于清洗和干燥半导体制造工艺等中使用的半导体晶片等基板。基板清洗装置具备：保持基板（W）的基板保持机构（10）和旋转基板保持机构（10）的旋转机构（20）。基板清洗装置的至少一个部件具有难以附着液滴的表面结构。

4. 发明申请

US20100105154A1 METHOD AND APPARATUS FOR PROCESSING SUBSTRATE 审中-公开
标题翻译：用于处理基板的方法和装置
公开(公告)号：US20100105154A1
公开(公告)日：2010-04-29
申请号：US12685820
申请日：2010-01-12
申请人： XINMING WANG , Daisuke Takagi , Akihiko Tashiro , Yukio Fukunaga , Akira Fukunaga , Akira Owatari , Yukiko Nishioka
发明人： XINMING WANG , Daisuke Takagi , Akihiko Tashiro , Yukio Fukunaga , Akira Fukunaga , Akira Owatari , Yukiko Nishioka
IPC分类号： H01L21/66 , H01L21/46
CPC分类号： H01L21/02068 , C23C18/1632 , C23C18/1689 , C23C18/1844 , H01L21/02074 , H01L21/288 , H01L21/67028 , H01L21/76849 , H01L21/76874 , H01L21/76883
摘要： A substrate processing method can securely form a metal film by electroless plating on an exposed surface of a base metal, such as interconnects, with increased throughput and without the formation of voids in the base metal. The substrate processing method includes: cleaning a surface of a substrate having a base metal formed in the surface with a cleaning solution comprising an aqueous solution of a carboxyl group-containing organic acid or its salt and a surfactant as an additive; bringing the surface of the substrate after the cleaning into contact with a processing solution comprising a mixture of the cleaning solution and a solution containing a catalyst metal ion, thereby applying the catalyst to the surface of the substrate; and forming a metal film by electroless plating on the catalyst-applied surface of the substrate.
摘要翻译：基板处理方法可以通过在贱金属（例如互连）的暴露表面上通过无电解电镀牢固地形成金属膜，具有增加的生产量并且在母材中不形成空隙。基板处理方法包括：用包含含羧基的有机酸或其盐和表面活性剂的水溶液作为添加剂的清洗溶液清洗在表面形成的基体金属的基材的表面; 使清洗后的基板的表面与包含清洗液和含有催化剂金属离子的溶液的混合物的处理溶液接触，从而将催化剂施加到基板的表面; 以及通过在基板的催化剂涂覆表面上通过无电镀形成金属膜。

5. 发明申请

US20080000509A1 Cleaning apparatus and cleaning method 审中-公开
标题翻译：清洁装置和清洁方法
公开(公告)号：US20080000509A1
公开(公告)日：2008-01-03
申请号：US11882565
申请日：2007-08-02
申请人： Ryosuke Yonekura , Yukiko Nishioka , Mitsuo Miyashita , Yoshikazu Ariga
发明人： Ryosuke Yonekura , Yukiko Nishioka , Mitsuo Miyashita , Yoshikazu Ariga
IPC分类号： B08B9/00
CPC分类号： H01L21/67051 , B08B3/02 , H01L21/67028
摘要： A cleaning apparatus in which cleaning and drying can be carried out without the risk of reverse contamination of the cleaned object after the drying process. The cleaning apparatus includes a supporting device for supporting an object to be cleaned, and a cleaning cup surrounding the supporting device to prevent splashing of a cleaning liquid. The cleaning apparatus includes a cleaning device for cleaning an inner wall of the cleaning cup with a cleaning liquid.
摘要翻译：可以进行清洁和干燥的清洁装置，而不会在干燥过程之后被清洁物体反向污染的风险。清洁装置包括用于支撑待清洁物体的支撑装置和围绕支撑装置的清洁杯，以防止清洗液体飞溅。清洁装置包括用清洁液清洁清洁杯的内壁的清洁装置。

6. 发明授权

US06932946B2 Ozone generator 有权
标题翻译：臭氧发生器
公开(公告)号：US06932946B2
公开(公告)日：2005-08-23
申请号：US09885102
申请日：2001-06-21
申请人： Ryoichi Shinjo , Minoru Harada , Yukiko Nishioka
发明人： Ryoichi Shinjo , Minoru Harada , Yukiko Nishioka
IPC分类号： C01B13/11 , H01T23/00 , B01J19/08
CPC分类号： C01B13/11 , C01B2201/12 , C01B2201/22
摘要： An ozone generator comprises a pair of spaced opposing electrodes, electrically conductive members connecting the pair of electrodes to a high-voltage alternating-current power source to generate an electric discharge between the electrodes, and a dielectric provided between the opposing electrodes. A gas flow passage for allowing flow of a material gas therethrough is defined by the surfaces of the electrodes. At least one of the surfaces of the pair of electrodes has a plurality of parallel grooves. The material gas flows in a space between the plurality of grooves and the dielectric, in a direction transverse to the grooves.
摘要翻译：臭氧发生器包括一对间隔的相对电极，将该对电极连接到高压交流电源的导电构件，以在电极之间产生放电，以及设置在相对电极之间的电介质。用于允许材料气体流过其中的气体流动通道由电极的表面限定。该对电极的至少一个表面具有多个平行的凹槽。材料气体在横向于槽的方向上在多个槽和电介质之间的空间中流动。

7. 发明申请

US20050050946A1 Cleaning evaluation method for a substrate 失效
标题翻译：基材清洗评估方法
公开(公告)号：US20050050946A1
公开(公告)日：2005-03-10
申请号：US10932083
申请日：2004-09-02
申请人： Yukiko Nishioka , Yoshikazu Ariga
发明人： Yukiko Nishioka , Yoshikazu Ariga
IPC分类号： H01L21/304 , B08B13/00 , G01M99/00 , H01L23/544 , H01L21/66 , G01M19/00
CPC分类号： B08B13/00 , H01L22/34 , H01L2924/0002 , H01L2924/00
摘要： The present invention relates to a cleaning evaluation method for evaluating a surface cleanliness of a substrate which has been cleaned after being polished. This method includes, preparing a dummy substrate having a metal film formed on a surface thereof and a monitor substrate on which a cleaning evaluation is performed, polishing the dummy substrate, after polishing the dummy substrate, polishing the monitor substrate without dressing a polishing surface of a polishing table, cleaning the monitor substrate, and evaluating the surface cleanliness of the monitor substrate which has been cleaned.
摘要翻译：本发明涉及一种用于评价在抛光后被清洗的基板的表面清洁度的清洁评估方法。该方法包括：准备在其表面上形成有金属膜的虚设基板和进行清洁评估的监视基板，对该虚设基板进行研磨后对该虚设基板进行研磨，对该监视基板进行研磨，抛光台，清洁监视器基板，以及评估已清洁的监视器基板的表面清洁度。

8. 发明授权

US07155963B2 Cleaning evaluation method for a substrate 失效
标题翻译：基材清洗评估方法
公开(公告)号：US07155963B2
公开(公告)日：2007-01-02
申请号：US10932083
申请日：2004-09-02
申请人： Yukiko Nishioka , Yoshikazu Ariga
发明人： Yukiko Nishioka , Yoshikazu Ariga
IPC分类号： H01L21/66 , G01M19/00
CPC分类号： B08B13/00 , H01L22/34 , H01L2924/0002 , H01L2924/00
摘要： The present invention relates to a cleaning evaluation method for evaluating a surface cleanliness of a substrate which has been cleaned after being polished. This method includes preparing a dummy substrate having a metal film formed on a surface thereof and a monitor substrate on which a cleaning evaluation is performed, and polishing the dummy substrate. After polishing the dummy substrate, the monitor substrate is polished without dressing a polishing surface of a polishing table, the monitor substrate is cleaned, and the surface cleanliness of the monitor substrate which has been cleaned is evaluated.
摘要翻译：本发明涉及一种用于评价在抛光后被清洗的基板的表面清洁度的清洁评估方法。该方法包括制备在其表面上形成有金属膜的虚拟基板和在其上执行清洁评估的监视器基板，以及抛光该虚设基板。在抛光虚拟基板之后，在不修整抛光台的研磨面的情况下对监视器基板进行抛光，对显示器基板进行清洁，并对已经清洗的显示器基板的表面清洁度进行评价。

9. 发明申请

US20050020194A1 Method and apparatus for polishing a workpiece 有权
标题翻译：抛光工件的方法和设备
公开(公告)号：US20050020194A1
公开(公告)日：2005-01-27
申请号：US10883772
申请日：2004-07-06
申请人： Tatsuya Kohama , Yukiko Nishioka , Yoshikazu Ariga
发明人： Tatsuya Kohama , Yukiko Nishioka , Yoshikazu Ariga
IPC分类号： B24B1/00 , B24B53/017 , B24B57/02 , H01L21/304
CPC分类号： B24B37/04 , B24B57/02
摘要： A method and apparatus for polishing a workpiece are set forth which can polish the workpiece at a constant rate at a stable condition even when plural workpieces are continually polished. The method comprises dressing a polishing surface of a polishing table while supplying a dressing solution. After the dressing, the dressing solution remaining on the polishing surface is removed by rotating the polishing table at a dewatering rotation speed while stopping the supply of the dressing solution. Then, the workpiece is polished by making the workpiece slidingly contact with the polishing surface while supplying a polishing solution to the polishing surface.
摘要翻译：阐述了一种用于抛光工件的方法和装置，即使当多个工件被连续抛光时，其可以以稳定的状态以恒定的速度抛光工件。该方法包括在提供敷料溶液的同时修整抛光台的抛光表面。修整后，通过在停止供给敷料溶液的同时以脱水转速旋转研磨台，除去留在研磨面上的敷料液。然后，通过使工件与研磨面滑动接触，同时向研磨面供给研磨液，抛光工件。

10. 发明授权

US5688289A Method of laundering clothes and textiles 失效
标题翻译：洗衣服和纺织品的方法
公开(公告)号：US5688289A
公开(公告)日：1997-11-18
申请号：US637342
申请日：1996-04-25
申请人： Yukiko Nishioka , Ryoichi Shinjo , Yoshihiro Ishii , Tadao Yamanaka
发明人： Yukiko Nishioka , Ryoichi Shinjo , Yoshihiro Ishii , Tadao Yamanaka
IPC分类号： D06F17/12 , D06F35/00 , D06L4/50 , D06L3/04
CPC分类号： D06F35/006 , D06L3/04
摘要： An improved method of laundering clothes and textiles comprises: providing a washing machine having a tub furnished with a fixed outer shell 11 and an inner cylinder 12 that is provided within the outer shell 11, that is rotatably supported on a horizontal rotating shaft 13 and that has a plurality of orifices in the outer peripheral wall through which a washing solution can pass; putting the clothes and textiles into the inner cylinder 12; charging the outer shell 11 with a washing solution Q having a polyelectrolyte containing detergent dissolved therein; and laundering the clothes and textiles with ozone gas from an ozonizer 21 being introduced from an ozone gas supply port 24a directly into the washing solution Q at a temperature of from about 40.degree. C. to less than 50.degree. C., preferably from about 40.degree. C. to about 45.degree. C. between the outer shell 11 and inner cylinder 12. The method has such a great laundering power that severe soiling of the collar and yellowing can be removed in a regular washing cycle without employing any preliminary or post treatments. In addition, the method can be implemented with existing commercial washing machines with ozone being readily introduced into washing solutions even if no special means is employed to mix them with ozone gas.
摘要翻译：一种改进的衣物和纺织品洗涤方法包括：提供一种洗衣机，其具有装有固定外壳11和设置在外壳11内的内筒12的桶，该外筒11可旋转地支撑在水平旋转轴13上，并且在外周壁上具有多个孔，洗涤液可以穿过该孔; 将衣服和纺织品放入内筒12中; 用溶解有聚电解质的洗涤剂的洗涤液Q对外壳11进行充电; 用来自臭氧气体21的臭氧气体从臭氧气体供给口24a直接进入洗涤液Q的臭氧气体在约40℃至小于50℃的温度下洗涤衣物和纺织品，优选约40℃ 在外壳11和内筒12之间的温度为约-45℃。该方法具有如此大的洗涤能力，即可以在常规洗涤循环中清除衣领的严重污染并且不会使用任何预处理或后处理。此外，该方法可以用现有的商业洗衣机来实现，即使没有采用特殊方法将臭氧与臭氧气体混合，臭氧也容易引入洗涤溶液中。

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