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1. 发明授权

US07183069B2 Reagent, method and apparatus for measuring amylase activity 有权
标题翻译：用于测量淀粉酶活性的试剂，方法和仪器
公开(公告)号：US07183069B2
公开(公告)日：2007-02-27
申请号：US10383007
申请日：2003-03-06
申请人： Masaki Yamaguchi , Hiroshi Yoshida , Nobutaka Kusaba , Yasufumi Mizuno
发明人： Masaki Yamaguchi , Hiroshi Yoshida , Nobutaka Kusaba , Yasufumi Mizuno
IPC分类号： C12Q1/40
CPC分类号： G01N33/52 , C12Q1/40
摘要： An object of the present invention is to provide a means for measuring amylase activity existing in biological samples such as saliva in a more convenient manner and is particularly to provide a means (reagent for measurement, method for measurement and apparatus) by which a sample containing high concentrations of amylase is measured. There has been found a means (reagent for measurement, method for measurement and apparatus), whereby amylase activity in an amylase sample having a high activity value can be quite conveniently measured by making an oligosaccharide substrate carry on a support in an enzymatic method for measuring amylase activity using a modified oligosacharide substrate, whereupon the present invention has been achieved.
摘要翻译：本发明的目的是提供一种用于以更方便的方式测量存在于生物样品例如唾液中的淀粉酶活性的方法，并且特别地提供一种用于测量的装置（测量方法，测量方法和装置），通过该装置测量高浓度的淀粉酶。已经发现了一种方法（用于测量的试剂，测量方法和装置），其中具有高活性值的淀粉酶样品中的淀粉酶活性可以通过使寡糖底物在酶法测量中进行支持而非常方便地测量使用改性的寡糖基底的淀粉酶活性，从而实现了本发明。

2. 发明授权

US07186696B2 Reagent and method for measuring amylase 有权
标题翻译：试剂和测定淀粉酶的方法
公开(公告)号：US07186696B2
公开(公告)日：2007-03-06
申请号：US10379094
申请日：2003-03-04
申请人： Masaki Yamaguchi , Hiroshi Yoshida , Nobutaka Kusaba
发明人： Masaki Yamaguchi , Hiroshi Yoshida , Nobutaka Kusaba
IPC分类号： A01N43/04
CPC分类号： C12Q1/40 , C12Q1/54
摘要： An object of the present invention is to provide a means for the measurement of amylase activity that exists in a biological sample such as saliva in a more convenient manner and particularly to provide a means (method and reagent) where a sample containing amylase in high concentration is directly measured without dilution. In the present invention, there has been found a method, which is an enzymatic method using a modified oligosaccharide substrate, comprising adding saccharide such as oligosaccharide that is competitive to the oligosaccharide substrate whereupon amylase activity in an amylase sample having a high activity value can be directly measured without dilution, and a result, the present invention has been achieved.
摘要翻译：本发明的目的是提供一种用于以更方便的方式测定存在于生物样品如唾液中的淀粉酶活性的方法，特别是提供一种方法（方法和试剂），其中含有高浓度淀粉酶的样品直接测量而不稀释。在本发明中，已经发现了使用改性的寡糖底物的酶法，其包括向寡糖底物添加竞争性低聚糖等糖类，由此具有高活性值的淀粉酶样品中的淀粉酶活性可以是不经稀释直接测量，结果，本发明已经实现。

3. 发明授权

US06566064B1 Method for anticipating sensitivity to medicine for osteoporosis 失效
标题翻译：预测骨质疏松症药物敏感度的方法
公开(公告)号：US06566064B1
公开(公告)日：2003-05-20
申请号：US09572891
申请日：2000-05-18
申请人： Masataka Shiraki , Yasuyoshi Ouchi , Takayuki Hosoi , Nobutaka Kusaba , Toshiaki Baba , Hiroshi Yoshida
发明人： Masataka Shiraki , Yasuyoshi Ouchi , Takayuki Hosoi , Nobutaka Kusaba , Toshiaki Baba , Hiroshi Yoshida
IPC分类号： C12Q168
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/156
摘要： A method for anticipating sensitivity to a medicine for osteoporosis is provided which is characterized by analyzing respective genetic polymorphisms of a vitamin D receptor gene, an estrogen receptor gene, and an apolipoprotein E gene from a genome DNA contained in a sample obtained from a human, and anticipating, based on the analyzed combination of the genetic polymorphisms, that the sample is derived from an individual who shows a specific priority to sensitivities to a plurality of remedies for osteoporosis. A reagent for simultaneously detecting genetic polymorphisms is also provided which contains amplification primers and/or detection probes specific to respective genes of the vitamin D receptor gene, apolipoprotein E gene, and estrogen receptor gene. Further, a method for simultaneously detecting these genes, and a method for selecting remedies for bone disease based on the genetic polymorphisms are provided. According to the method of the present invention, a diagnosis as to which remedy, or medicine, for osteoporosis a subject patient has higher sensitivity can be made before the administration of the medicine so that selection of an appropriate medicine is possible and the QOL (quality of life) of the patient can be improved.
摘要翻译：本发明提供一种用于预测对于骨质疏松症药物的敏感性的方法，其特征在于分析来自人获得的样品中含有的基因组DNA中的维生素D受体基因，雌激素受体基因和载脂蛋白E基因的遗传多态性，并且基于所分析的遗传多态性的组合，预期样品来源于对多种骨质疏松症的治疗方案具有特定优先权的个体。还提供了用于同时检测遗传多态性的试剂，其包含对维生素D受体基因，载脂蛋白E基因和雌激素受体基因的各自基因特异的扩增引物和/或检测探针。此外，提供了同时检测这些基因的方法，以及基于遗传多态性选择骨疾病补救方法。根据本发明的方法，可以在给药之前进行对患者具有较高敏感性的骨质疏松症的补救或药物的诊断，以便选择合适的药物是可行的，并且生活质量的生命）可以改善。

4. 发明授权

US09596124B2 Assistance device of network system 有权
标题翻译：网络系统辅助装置
公开(公告)号：US09596124B2
公开(公告)日：2017-03-14
申请号：US14005324
申请日：2011-03-23
申请人： Hiromi Sasaki , Hiroshi Yoshida , Takeshi Jinkawa , Masaki Namie , Hirohito Mizumoto , Yutaka Tahara , Shigenori Sawada
发明人： Hiromi Sasaki , Hiroshi Yoshida , Takeshi Jinkawa , Masaki Namie , Hirohito Mizumoto , Yutaka Tahara , Shigenori Sawada
IPC分类号： G06F15/16 , H04L12/24 , H04L12/40 , H04L12/403 , H04L29/12
CPC分类号： H04L41/04 , H04L12/40006 , H04L12/403 , H04L41/0853 , H04L41/0866 , H04L41/12 , H04L41/145 , H04L61/2038
摘要： A design assistance device includes: a design information storage section configured to store design information containing at least information of slave devices and information of a topology in a network system in accordance with a design created by a user; an actual configuration information generation section configured to generate actual configuration information containing at least the information of the slave devices and the information of the topology in the actual network system; a comparison section configured to compare the design information and the actual configuration information; and an output section configured to generate a comparison screen indicating the respective configurations of the designed network system and the actual network system along with their commonalities and differences and outputting the comparison screen to a display device. Thus, a technology can be provided which assists the user to easily compare the designed network configuration and the actual machine's network configuration.
摘要翻译：设计辅助装置包括：设计信息存储部分，被配置为根据由用户创建的设计，在网络系统中存储至少包含从设备信息和拓扑信息的设计信息; 实际配置信息生成部，被配置为生成至少包含所述从设备的信息和所述实际网络系统中的拓扑的信息的实际配置信息; 配置为比较设计信息和实际配置信息的比较部分; 以及输出部，其被配置为生成指示所设计的网络系统和实际网络系统的各自配置及其共同点和差异的比较屏幕，并将比较屏幕输出到显示设备。因此，可以提供一种技术，其帮助用户容易地比较设计的网络配置和实际机器的网络配置。

5. 发明授权

US09273370B2 Hot-rolled steel sheet, cold-rolled steel sheet, galvanized steel sheet, and methods of manufacturing the same 有权
标题翻译：热轧钢板，冷轧钢板，镀锌钢板及其制造方法
公开(公告)号：US09273370B2
公开(公告)日：2016-03-01
申请号：US13811902
申请日：2011-07-27
申请人： Nobuhiro Fujita , Kunio Hayashi , Riki Okamoto , Manabu Takahashi , Tetsuo Kishimoto , Hiroshi Yoshida
发明人： Nobuhiro Fujita , Kunio Hayashi , Riki Okamoto , Manabu Takahashi , Tetsuo Kishimoto , Hiroshi Yoshida
IPC分类号： C22C38/58 , C22C38/54 , C22C38/52 , C21D8/02 , C23C2/06 , C23C2/28 , C22C38/00 , C22C38/04 , B21B35/00 , C22C38/02 , C22C38/06 , C22C38/08 , C22C38/10 , C22C38/12 , C22C38/14 , C22C38/16 , C22C38/18 , C22C38/20 , C22C38/22 , C22C38/24 , C22C38/26 , C22C38/28 , C22C38/30 , C22C38/32 , C22C38/34 , C22C38/38 , C22C38/40 , C22C38/42 , C22C38/44 , C22C38/46 , C22C38/48 , C22C38/50 , C23C2/02 , C25D5/36 , C23C2/40
CPC分类号： C25D3/22 , B21B35/00 , B32B15/013 , C21D6/004 , C21D6/005 , C21D6/007 , C21D6/008 , C21D8/0205 , C21D8/0226 , C21D8/0236 , C21D8/0247 , C21D8/0263 , C21D8/0273 , C21D9/46 , C21D2201/05 , C21D2211/00 , C21D2211/001 , C21D2211/002 , C21D2211/005 , C21D2211/009 , C22C38/001 , C22C38/002 , C22C38/004 , C22C38/005 , C22C38/008 , C22C38/02 , C22C38/04 , C22C38/06 , C22C38/08 , C22C38/10 , C22C38/105 , C22C38/12 , C22C38/14 , C22C38/16 , C22C38/18 , C22C38/20 , C22C38/22 , C22C38/24 , C22C38/26 , C22C38/28 , C22C38/30 , C22C38/32 , C22C38/34 , C22C38/38 , C22C38/40 , C22C38/42 , C22C38/44 , C22C38/46 , C22C38/48 , C22C38/50 , C22C38/52 , C22C38/54 , C22C38/58 , C23C2/02 , C23C2/06 , C23C2/28 , C23C2/40 , C25D5/36
摘要： A hot-rolled steel sheet has an average value of the X-ray random intensity ratio of a {100} to {223} orientation group at least in a sheet thickness central portion that is in a sheet thickness range of ⅝ to ⅜ from a steel sheet surface of 1.0 to 6.0, an X-ray random intensity ratio of a {332} crystal orientation of 1.0 to 5.0, rC which is an r value in a direction perpendicular to a rolling direction of 0.70 to 1.10, and r30 which is an r value in a direction that forms an angle of 30° with respect to the rolling direction of 0.70 to 1.10.
摘要翻译：热轧钢板至少在片材厚度范围的板厚中央部具有{100} <011>〜{223} <110>取向基团的X射线随机强度比的平均值从1.0〜6.0的钢板表面的⅝至⅝，{332} <113>晶体取向的X射线随机强度比为1.0〜5.0，rC为与轧制方向垂直的方向的r值为0.70〜1.10，r30为相对于轧制方向为30°的方向的r值，为0.70〜1.10。

6. 发明授权

US09234861B2 Electrode for electrochemical measurement, electrolysis cell for electrochemical measurement, analyzer for electrochemical measurement, and methods for producing same 有权
标题翻译：电化学测定用电极，电化学测定用电解槽，电化学测定用分析装置及其制造方法
公开(公告)号：US09234861B2
公开(公告)日：2016-01-12
申请号：US13992514
申请日：2011-12-06
申请人： Hiroshi Kanemoto , Haruo Akahoshi , So Oguchi , Kenta Imai , Taku Sakazume , Hiroshi Yoshida
发明人： Hiroshi Kanemoto , Haruo Akahoshi , So Oguchi , Kenta Imai , Taku Sakazume , Hiroshi Yoshida
IPC分类号： G01N27/30 , C25B11/04 , H01M4/92 , G01N27/327 , G01N33/49
CPC分类号： G01N27/307 , C25B11/0426 , C25B11/0431 , C25B11/0473 , C25B11/0484 , C25F3/16 , C25F7/00 , G01N27/30 , G01N27/3271 , G01N27/403 , G01N33/4915 , H01M4/92 , H01M4/921 , H01M4/923 , H01M4/925
摘要： Provided are an electrode, an electrolysis cell, and an electrochemical analyzer that improve the long-term stability of analysis data. A working electrode, a counter electrode, and reference electrode are disposed in an electrolysis cell. The working electrode is obtained by forming a lead wire in a composite material having platinum or a platinum alloy as a base material, in which a metal oxide is dispersed, or in a laminated material obtained by laminating a valve metal and platinum such that the cross sectional crystal texture in the thickness direction of the platinum is formed in layers and the thickness of each layer of the platinum is 5 micrometers or less. The metal oxide is selected from among zirconium oxide, tantalum oxide, and niobium oxide, and the metal oxide content of the platinum or the platinum alloy is 0.005 to 1 wt % in terms of the zirconium, tantalum, or niobium metal.
摘要翻译：提供了提高分析数据的长期稳定性的电极，电解槽和电化学分析装置。工作电极，对电极和参比电极设置在电解槽中。工作电极是通过在具有铂或铂合金作为其中分散有金属氧化物的基材的复合材料中形成引线而获得的，或者通过层压阀金属和铂得到的层压材料，使得交叉铂的厚度方向上的截面晶体结构形成层，铂层的厚度为5微米以下。金属氧化物选自氧化锆，氧化钽和氧化铌，铂或铂合金的金属氧化物含量以锆，钽或铌金属换算为0.005〜1重量％。

7. 发明授权

US09064616B2 Conductive paste 有权
标题翻译：导电胶
公开(公告)号：US09064616B2
公开(公告)日：2015-06-23
申请号：US14005994
申请日：2012-04-05
申请人： Hiroshi Yoshida , Naoto Shindo , Tadashi Kanasaku , Shoko Masuda
发明人： Hiroshi Yoshida , Naoto Shindo , Tadashi Kanasaku , Shoko Masuda
IPC分类号： H01B1/22 , H01L31/00 , C03C8/18 , C09D5/24 , C03C8/02 , H01L31/0224
CPC分类号： H01B1/22 , C03C3/122 , C03C8/02 , C03C8/18 , C09D5/24 , H01L31/022425 , Y02E10/50
摘要： A conductive paste includes a conductive powder containing at least one of copper and nickel as a main component, a glass frit, and an organic vehicle, wherein the glass frit is a tellurium-based glass frit that essentially does not contain any lead component and contains tellurium as a network former in an amount of 35 to 70 mol % in terms of oxide, the tellurium-based glass frit containing silver as an essential component. The above conductive paste can provide favorable characteristics and favorably be used in the formation of light-receiving surface electrodes of a solar cell element even when the conductive paste includes one or more of copper and nickel as its conductive component.
摘要翻译：导电浆料包括含有铜和镍中的至少一种作为主要成分的导电粉末，玻璃料和有机载体，其中玻璃料是基本上不含任何铅成分的碲基玻璃料，碲作为网络前体，以氧化物计为35〜70摩尔％，以含有银为主要成分的碲系玻璃料。即使当导电浆料包括一种或多种铜和镍作为其导电组分时，上述导电浆料可以提供有利的特性，并且有利地用于形成太阳能电池元件的光接收表面电极。

8. 发明授权

US08867681B2 Transmission system, transmission device, and clock synchronization method 有权
标题翻译：传输系统，传输设备和时钟同步方法
公开(公告)号：US08867681B2
公开(公告)日：2014-10-21
申请号：US13248215
申请日：2011-09-29
申请人： Hiroshi Yoshida
发明人： Hiroshi Yoshida
IPC分类号： H04L7/00 , G06F1/12 , H04J3/06
CPC分类号： G06F1/12 , H04J3/0685
摘要： A transmission system which couples a plurality of transmission devices to a control device includes a first transmission device which is one of the plurality of transmission devices; a first calculation circuit which calculates a first difference value indicating a frequency difference value between a common clock supplied from the control device and a first clock as a clock used in the first transmission device; and a transmitter which reports the first difference value to a second transmission device other than the first transmission device, wherein the second transmission device comprises: a second calculation circuit which calculates a second difference value indicating a frequency difference value between the common clock and a second clock used in the second transmission device, and a frequency controller which controls an oscillator generating the second clock so that the second difference value approaches the first difference value reported from the first transmission device.
摘要翻译：将多个传输设备耦合到控制设备的传输系统包括作为多个传输设备之一的第一传输设备; 第一计算电路，其计算指示从所述控制装置提供的公共时钟与所述第一时钟之间的频率差值作为所述第一发送装置中使用的时钟的第一差值; 以及向所述第一发送装置以外的第二发送装置报告所述第一差分值的发送机，其中，所述第二发送装置包括：第二计算电路，其计算表示所述公共时钟与第二发送装置之间的频率差值的第二差分值在第二发送装置中使用的时钟，以及频率控制器，其控制产生第二时钟的振荡器，使得第二差值接近从第一发送装置报告的第一差值。

9. 发明申请

US20140133316A1 Parameter Estimation Device, Parameter Estimation Method, and Parameter Estimation Program 有权
标题翻译：参数估计装置，参数估计方法和参数估计方案
公开(公告)号：US20140133316A1
公开(公告)日：2014-05-15
申请号：US14129034
申请日：2012-06-12
申请人： Hiroshi Yoshida
发明人： Hiroshi Yoshida
IPC分类号： H04L12/26
CPC分类号： H04L43/0888 , H04L43/04 , H04L47/25
摘要： A parameter estimation device 600 includes: a communication throughput acquiring part 601 for acquiring communication throughput that is an amount of data transmitted per unit time; and a function specification parameter estimating part 602 for estimating a function specification parameter for specifying a probability density function where communication throughput at a second time point later than a first time point is a random variable, based on the communication throughput acquired by the first time point.
摘要翻译：参数估计装置600包括：通信吞吐量获取部601，用于获取作为每单位时间发送的数据量的通信吞吐量; 以及功能指定参数估计部602，用于基于第一时间点获取的通信吞吐量，估计用于指定在第一时间点之后的第二时间点的通信吞吐量为随机变量的概率密度函数的功能指定参数。

10. 发明授权

US08628869B2 Magnetic media and magnetic recording devices using fluorine compounds 有权
标题翻译：使用氟化合物的磁介质和磁记录装置
公开(公告)号：US08628869B2
公开(公告)日：2014-01-14
申请号：US13361896
申请日：2012-01-30
申请人： Mina Amo , Katsumi Mabuchi , Hiroshi Yoshida , Bruno Marchon , Qing Dai
发明人： Mina Amo , Katsumi Mabuchi , Hiroshi Yoshida , Bruno Marchon , Qing Dai
IPC分类号： G11B5/66
CPC分类号： C07D249/18 , C07D403/12 , C07D403/14 , G11B5/725
摘要： According to one embodiment, a lubricant includes a perfluoropolyether having a chemical structure of: wherein Rf is at least one of: —CF2O(CF2CF2O)m(CF2O)nCF2— and —CF2CF2O(CF2CF2CF2O)kCF2CF2—, with m representing 0 or a positive integer, n representing 0 or a positive integer, and k representing 0 or a positive integer, and wherein R1 to R4 are selected from a group consisting of —H or with at least one of R1 to R4 being
摘要翻译：根据一个实施方案，润滑剂包括具有以下化学结构的全氟聚醚：其中Rf为至少一种：-CF 2 O（CF 2 CF 2 O）m（CF 2 O）n CF 2 - 和-CF 2 CF 2 O（CF 2 CF 2 CF 2 O）k CF 2 CF 2 - ，其中m表示0或正整数，n表示0或正整数，k表示0或正整数，并且其中R 1至R 4选自-H或与R 1至R 4中的至少一个为

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