专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08252895B2 Cyclic peptide compounds 失效
标题翻译：环肽化合物
公开(公告)号：US08252895B2
公开(公告)日：2012-08-28
申请号：US12840488
申请日：2010-07-21
申请人： Masahiro Neya , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
发明人： Masahiro Neya , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
IPC分类号： C07K7/64
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种具有抗丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，涉及其制备方法，其包括在温和酸性条件和以下氨基酸变化反应等，涉及包含其的药物组合物，以及在人或动物中预防和/或治疗丙型肝炎的方法。

2. 发明授权

US07872097B2 Cyclic peptide compounds 有权
标题翻译：环肽化合物
公开(公告)号：US07872097B2
公开(公告)日：2011-01-18
申请号：US12083551
申请日：2006-10-26
申请人： Masahiro Neya , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
发明人： Masahiro Neya , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
IPC分类号： C07K7/64
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种具有抗丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，涉及其制备方法，其包括在温和酸性条件和以下氨基酸变化反应等，涉及包含其的药物组合物，以及在人或动物中用于预防和/或治疗丙型肝炎的方法。

3. 发明申请

US20100286033A1 NEW CYCLIC PEPTIDE COMPOUNDS 失效
标题翻译：新型循环肽化合物
公开(公告)号：US20100286033A1
公开(公告)日：2010-11-11
申请号：US12840488
申请日：2010-07-21
申请人： Masahiro NEYA , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
发明人： Masahiro NEYA , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
IPC分类号： A61K38/12 , C07K7/06 , C07K7/50 , A61P31/12
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种具有抗丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，涉及其制备方法，其包括在温和酸性条件和以下氨基酸变化反应等，涉及包含其的药物组合物，以及在人或动物中用于预防和/或治疗丙型肝炎的方法。

4. 发明申请

US20090170755A1 Cyclic Peptide Compounds 有权
标题翻译：环肽化合物
公开(公告)号：US20090170755A1
公开(公告)日：2009-07-02
申请号：US12083551
申请日：2006-10-26
申请人： Masahiro Neya , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
发明人： Masahiro Neya , Seiji Yoshimura , Kazunori Kamijyo , Takuya Makino , Minoru Yasuda , Toshio Yamanaka , Eisaku Tsujii , Yukiko Yamagishi
IPC分类号： A61K38/12 , C07K7/64 , C07K7/06 , A61P31/12
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种具有抗丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，涉及其制备方法，其包括在温和酸性条件和以下氨基酸变化反应等，涉及包含其的药物组合物，以及在人或动物中预防和/或治疗丙型肝炎的方法。

5. 发明授权

US08603975B2 Cyclic peptide compounds 有权
标题翻译：环肽化合物
公开(公告)号：US08603975B2
公开(公告)日：2013-12-10
申请号：US12598404
申请日：2008-04-25
申请人： Toshio Yamanaka , Hidenori Ohki , Junya Ishida , Ayako Toda , Yu Harayama , Takuya Makino , Shigeki Kunikawa , Hiroaki Mizuno , Hiroaki Ohtake
发明人： Toshio Yamanaka , Hidenori Ohki , Junya Ishida , Ayako Toda , Yu Harayama , Takuya Makino , Shigeki Kunikawa , Hiroaki Mizuno , Hiroaki Ohtake
IPC分类号： A61K38/12 , A61P31/12
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种基于对丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，其制备方法，包含其的药物组合物，以及在人或动物中预防和/或治疗丙型肝炎的方法。

6. 发明申请

US20100120672A1 CYCLIC PEPTIDE COMPOUNDS 有权
标题翻译：环肽类化合物
公开(公告)号：US20100120672A1
公开(公告)日：2010-05-13
申请号：US12598404
申请日：2008-04-25
申请人： Toshio Yamanaka , Hidenori Ohki , Junya Ishida , Ayako Toda , Yu Harayama , Takuya Makino , Shigeki Kunikawa , Hiroaki Mizuno , Hiroaki Ohtake
发明人： Toshio Yamanaka , Hidenori Ohki , Junya Ishida , Ayako Toda , Yu Harayama , Takuya Makino , Shigeki Kunikawa , Hiroaki Mizuno , Hiroaki Ohtake
IPC分类号： A61K38/12 , C07K7/64 , A61P31/12
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种基于对丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，其制备方法，包含其的药物组合物，以及在人或动物中预防和/或治疗丙型肝炎的方法。

7. 发明授权

US07061455B2 Optical switching element, and switching device and image display apparatus each using the optical switching element 失效
公开(公告)号：US07061455B2
公开(公告)日：2006-06-13
申请号：US11102740
申请日：2005-04-11
申请人： Takuya Makino
发明人： Takuya Makino
IPC分类号： G09G3/34
CPC分类号： G02B26/0841 , G02B26/02
摘要： An optical switching element having a simple configuration and high response and capable of performing gradation display by area gradation is provided. In a state where a light extracting portion is in contact with an upper substrate, light enters the light extracting portion from the upper substrate, emits from the back face of the light extracting portion, is passed through a lower substrate, and becomes transmission light. In a state where the light extracting portion is attracted by the lower substrate side, the incident light is totally reflected by a total reflection face, and total reflection light emits from a V-shaped groove. The incident light can be switched in two directions and obtained as the transmission light and the total reflection light. To display one pixel, in the light extracting portion and a plurality of other light extracting portions, the incident light is selectively taken by being switched between two directions of the transmission light and the total reflection light, thereby enabling the gradation display by area gradation to be performed.

8. 发明申请

US20060098311A1 Micro-mirror and a method for fabricating the same 失效
公开(公告)号：US20060098311A1
公开(公告)日：2006-05-11
申请号：US11297929
申请日：2005-12-08
申请人： Masaki Hara , Takuya Makino , Kazuhito Hori , Kazuhiro Hane , Minoru Sasaki
发明人： Masaki Hara , Takuya Makino , Kazuhito Hori , Kazuhiro Hane , Minoru Sasaki
IPC分类号： G02B7/182
CPC分类号： G02B26/0866 , G02B26/0833 , Y10S359/904
摘要： A micro-mirror for deflecting an incident light is disclosed, wherein the micro-mirror comprises: a mirror section for reflecting an incident light issued from a laser diode; a hinge section including a fixed section and a movable section each having a flat surface; and a drive section having a bi-morph structure made of two or more of materials having different heat expansion coefficient for deflecting said mirror section to change relative angle to said incident light.

9. 发明申请

US20100256048A1 POLYPEPTIDE COMPOUND 审中-公开
标题翻译：多肽化合物
公开(公告)号：US20100256048A1
公开(公告)日：2010-10-07
申请号：US12740129
申请日：2008-10-28
申请人： Masaki Tomishima , Hiroshi Morikawa , Takuya Makino , Masashi Imanishi , Natsuko Kayakiri , Toru Asano , Takanobu Araki , Toshiya Nakagawa
发明人： Masaki Tomishima , Hiroshi Morikawa , Takuya Makino , Masashi Imanishi , Natsuko Kayakiri , Toru Asano , Takanobu Araki , Toshiya Nakagawa
IPC分类号： A61K38/12 , C07K7/54 , A61P31/10
CPC分类号： C07K7/56 , A61K38/00
摘要： [Problems] To provide an antibacterial agent, particularly a novel polypeptide compound having an antifungal action. [Means for Solution] As a result of an extensive study on a novel antifungal agent, the inventors have found that an excellent anti-deep-fungal activity is exhibited by introducing a cyclohexylmethylamino group or a piperidylmethylamino group as a partial structure of a natural polypeptide compound, and completed the present invention. The compound of the present invention has an excellent antibacterial activity and is therefore useful as an agent for preventing or treating various fungal infections.
摘要翻译： [问题]提供抗菌剂，特别是具有抗真菌作用的新型多肽化合物。 [解决方案]作为对新型抗真菌剂的广泛研究的结果，本发明人发现通过引入环己基甲基氨基或哌啶基甲基氨基作为天然多肽的部分结构，显示出优异的抗深度真菌活性化合物，完成了本发明。本发明的化合物具有优异的抗菌活性，因此可用作预防或治疗各种真菌感染的药剂。

10. 发明授权

US07000686B2 Heat transport device and electronic device 失效
标题翻译：热输送装置和电子装置
公开(公告)号：US07000686B2
公开(公告)日：2006-02-21
申请号：US11043132
申请日：2005-01-27
申请人： Takuya Makino , Masaki Hara
发明人： Takuya Makino , Masaki Hara
IPC分类号： F28D15/02
CPC分类号： H01L23/427 , F28D15/043 , H01L2924/0002 , H01L2924/00
摘要： A heat transport device includes an evaporator, a condenser, and a vapor channel and a plurality of liquid channels that connect the evaporator and the condenser. The evaporator generates a capillary force to circulate working fluid. This structure prevents the performance deterioration and malfunction due to the entry of vapor-phase working fluid into the liquid channels. Since the cross-sectional areas of the liquid channels gradually decrease from the condenser toward the evaporator, the capillary force at the liquid channels can be increased, and vapor-phase working fluid is prevented from entering the liquid channels. Wicks and the portions of the liquid channels adjacent thereto are filled with liquid-phase working fluid even after dryout occurs, stable operation is achieved.
摘要翻译：热传输装置包括蒸发器，冷凝器和蒸汽通道以及连接蒸发器和冷凝器的多个液体通道。蒸发器产生毛细管力以循环工作流体。这种结构防止由于气相工作流体进入液体通道而引起的性能劣化和故障。由于液体通道的横截面积从冷凝器朝向蒸发器逐渐减小，所以可以增加液体通道处的毛细管力，并且防止气相工作流体进入液体通道。即使在干燥发生之后，芯子和与其相邻的液体通道的部分填充有液相工作流体，因此实现了稳定的操作。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式